Skip to content
Disclosery

SPRO SPERO THERAPEUTICS INC

Follow

COM (common), issuer CIK 1701108

48 managers (50 13F filers) reported a position in SPRO shares at 2026-03-31, 20,643,241 shares in all. 5 filers opened a position and 13 filers sold out during the quarter.

Managers
48
13F filers
50
New
5
Added
12
Reduced
11
Sold out
13
Shares held by filers
20,643,241

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2026

Filers in the available 13F reports with a share position at 2026-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
GSK plc9,190,606$21.5M3.59%013F-HRTimeline
Pfizer Inc2,362,348$5.5M2.31%013F-HRTimeline
VANGUARD GROUP INCgroup of 3 filers holding2,089,441$4.89MnewTimeline
RENAISSANCE TECHNOLOGIES LLC1,189,235$2.78M<0.01%-90,28713F-HRTimeline
Alphabet Inc.in group Alphabet Inc.889,979$2.08M0.05%013F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP885,631$2.07M<0.01%+513,06113F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC519,922$1.22M<0.01%-9,27313F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.433,202$1.01M<0.01%-41413F-HRTimelineGroup
Anson Funds Management LPin group Anson Funds Management LP421,956$987K0.13%-203,10613F-HR/ATimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC376,458$881K<0.01%-21,40613F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…333,115$779K<0.01%+39,41513F-HRTimelineGroup
GSA CAPITAL PARTNERS LLP278,304$651K0.04%+99,37413F-HRTimeline
STATE STREET CORPin group STATE STREET CORP214,751$503K<0.01%+4,60013F-HRTimelineGroup
Ionic Capital Management LLC195,939$458K0.38%013F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC194,301$455K<0.01%+74,86713F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP157,072$368K<0.01%new13F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP120,984$283K<0.01%013F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC114,800$269K0.01%013F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC106,345$249K<0.01%-51,99913F-HRTimelineGroup
Shay Capital LLC70,354$165K0.02%+10,06513F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.59,668$140K<0.01%+16,08913F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.45,374$106K<0.01%+20,66913F-HRTimelineGroup
Quadrature Capital Ltdin group Quadrature Capital Ltd40,128$93.9K<0.01%+2,32913F-HRTimelineGroup
Capital Asset Advisory Services LLC32,548$92.4K<0.01%013F-HRTimeline
OMERS ADMINISTRATION Corp39,400$92.2K<0.01%-91,72713F-HRTimeline
Verdad Advisers, LP33,455$78.3K0.09%new13F-HRTimeline
SIMPLEX TRADING, LLC30,304$70.9K<0.01%-5,38213F-HRTimeline
Three Seasons Wealth, LLC30,000$70.2K0.03%013F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP29,768$69.2K<0.01%013F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co28,565$66.8K<0.01%013F-HRTimelineGroup
Schonfeld Strategic Advisors LLC20,314$47.5K<0.01%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC19,135$44.8K<0.01%+19,11813F-HRTimelineGroup
Assenagon Asset Management S.A.18,636$43.6K<0.01%013F-HRTimeline
OCCUDO QUANTITATIVE STRATEGIES LP16,421$41.2K<0.01%new13F-HRTimeline
INTREPID FAMILY OFFICE LLC16,279$38.1K0.03%-148,72113F-HRTimeline
Torrey Growth & Income Advisors17,025$37.6K0.02%013F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP7,678$17.9K<0.01%+1,20113F-HRTimelineGroup
FNY Investment Advisers, LLC5,300$12K0.01%013F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY4,552$10.7K<0.01%+4,23913F-HRTimelineGroup
UBS Group AGin group UBS Group AG3,009$7.04K<0.01%-113,43813F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.290$678<0.01%013F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO236$529<0.01%-5,13713F-HR/ATimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN200$468<0.01%013F-HR/ATimelineGroup
US BANCORP \DE\in group US BANCORP \DE\151$353<0.01%013F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS40$94<0.01%013F-HRTimelineGroup
Farther Finance Advisors, LLC10$25<0.01%013F-HRTimeline
SBI Securities Co., Ltd.9$21<0.01%013F-HRTimeline
Caitong International Asset Management …3$7<0.01%new13F-HRTimeline