Skip to content
Disclosery

PYXS PYXIS ONCOLOGY INC

Follow

Stock (common), issuer CIK 1782223

78 managers (79 13F filers) reported a position in PYXS shares at 2025-12-31, 30,196,015 shares in all. 19 filers opened a position and 14 filers sold out during the quarter.

Managers
78
13F filers
79
New
19
Added
25
Reduced
18
Sold out
14
Shares held by filers
30,196,015

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

Each filer's latest stake. The shares are the aggregate the reporting persons state, which can include entities that file no 13F.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Pfizer Inc7,032,770$8.09M3.42%013F-HRTimeline
Laurion Capital Management LP4,796,479$5.52M0.38%+1,170,50513F-HR/ATimeline
GordonMD Global Investments LPin group GordonMD Global Investments LP4,121,870$4.74M3.4%13F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC2,335,768$2.69M<0.01%+171,80613F-HRTimelineGroup
Palo Alto Investors LP1,037,421$1.19M0.17%013F-HRTimeline
683 Capital Management, LLCin group 683 Capital Management, LLC891,910$1.03M0.09%+366,91013F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC786,010$904K<0.01%+482,31013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.784,077$902K<0.01%+100,37513F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC743,107$855K<0.01%-72,22413F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC728,380$838K<0.01%+152,04413F-HRTimeline
Atle Fund Management AB617,245$710K0.23%new13F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/587,851$676K<0.01%-28,07113F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC577,211$664K<0.01%+32,70313F-HRTimelineGroup
Longaeva Partners L.P.503,214$579K0.07%013F-HRTimeline
UBS Group AGin group UBS Group AG392,766$452K<0.01%+19,03913F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP389,764$448K<0.01%new13F-HRTimelineGroup
Decheng Capital LLC326,810$376K0.05%013F-HRTimeline
ExodusPoint Capital Management, LP317,769$365K<0.01%new13F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd289,033$332K0.01%+271,33413F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC243,589$280K<0.01%-93,77013F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP241,637$278K<0.01%+39,58213F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.188,136$216K<0.01%new13F-HRTimelineGroup
Graham Capital Management, L.P.183,942$212K0.01%new13F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp165,044$190K<0.01%013F-HRTimelineGroup
Qube Research & Technologies Ltd145,813$168K<0.01%+115,00513F-HRTimeline
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding128,152$147K+29,127Timeline
NewEdge Wealth, LLC116,006$133K<0.01%013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…108,414$125K<0.01%-29,11713F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP101,948$117K<0.01%+1,17513F-HRTimelineGroup
Quadrature Capital Ltdin group Quadrature Capital Ltd100,536$116K<0.01%new13F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY89,222$103K<0.01%-17,38513F-HR/ATimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC86,145$99.1K<0.01%-39,30913F-HR/ATimelineGroup
TORONTO DOMINION BANKin group TORONTO DOMINION BANK75,000$86.2K<0.01%new13F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC72,700$83.6K<0.01%-4,00013F-HRTimeline
OMERS ADMINISTRATION Corp67,000$77K<0.01%new13F-HRTimeline
Cable Car Capital, LP61,606$70.8K<0.01%013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC60,385$69.4K<0.01%+57,42413F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA55,551$64K<0.01%-22,42913F-HRTimelineGroup
J. Derek Lewis & Associates Inc.53,000$61K0.01%13F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP50,066$57.6K<0.01%+13,55013F-HRTimelineGroup
UNIVERSITY OF CHICAGO48,731$56K0.03%013F-HRTimeline
Velan Capital Investment Management LP40,000$46K0.03%-15,00013F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC39,755$45.7K<0.01%-21,40013F-HRTimeline
HRT FINANCIAL LP39,649$45K<0.01%+24,25113F-HRTimeline
LPL Financial LLC35,102$40.4K<0.01%+21,10013F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC31,936$36.7K<0.01%new13F-HRTimelineGroup
Lighthouse Investment Partners, LLCin group Lighthouse Investment Partner…28,860$33.2K<0.01%new13F-HRTimelineGroup
Avanza Fonder AB27,345$31.4K<0.01%new13F-HRTimeline
Cetera Investment Advisers27,260$31.3K<0.01%-50013F-HRTimeline
Maia Wealth LLC21,959$29.6K0.01%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS24,279$27.9K<0.01%+22,56213F-HRTimelineGroup
Engineers Gate Manager LP22,816$26.2K<0.01%new13F-HRTimeline
FOX RUN MANAGEMENT, L.L.C.22,566$26K<0.01%new13F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.17,224$19.8K<0.01%+2,00313F-HRTimelineGroup
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.16,000$18.4K<0.01%new13F-HRTimelineGroup
FMR LLCin group FMR LLC12,858$14.8K<0.01%-2,59713F-HRTimelineGroup
PACES FERRY WEALTH ADVISORS, LLC11,440$13.2K0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…10,810$12.4K<0.01%-2,17213F-HRTimelineGroup
NewEdge Advisors, LLC10,250$11.8K<0.01%+10,00013F-HRTimeline
China Universal Asset Management Co., L…10,146$11.7K<0.01%-72513F-HRTimeline
SIMPLEX TRADING, LLC9,790$11.3K<0.01%+2,35713F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management8,227$9.46K<0.01%new13F-HRTimelineGroup
Winthrop Capital Management, LLC6,000$7K<0.01%013F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO5,514$6.34K<0.01%+1,00113F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…3,026$3.48K<0.01%+62813F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC2,902$3.34K<0.01%+1,62113F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN2,285$2.63K<0.01%+2,00013F-HRTimelineGroup
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.1,894$2.18K<0.01%new13F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.1,277$1.47K<0.01%-5713F-HRTimeline
NISA INVESTMENT ADVISORS, LLC961$1.1K<0.01%013F-HRTimeline
Physician Wealth Advisors, Inc.943$1.08K<0.01%013F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP500$575<0.01%013F-HRTimelineGroup
Cornerstone Financial Management LLC172$198<0.01%13F-HR/ATimeline
US BANCORP \DE\in group US BANCORP \DE\94$108<0.01%new13F-HRTimelineGroup
Arax Advisory Partners14$16<0.01%013F-HRTimeline
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…12$14<0.01%013F-HR/ATimelineGroup
SBI Securities Co., Ltd.1$1<0.01%-113F-HRTimeline
CWM, LLCin group CWM, LLC70$00%-34413F-HRTimelineGroupValue filed as zero, left out of ratios.

Events

  • GordonMD Global Investments LP and 3 other reporting persons reported 20,441,948 PYXS shares, 16.4% of the class, as of 2026-10-01, in a 13G/A filed 2026-10-09. 0000919574-26-006818

    Accepted , ingested

  • Coastlands Capital LP and 4 other reporting persons reported 6,448,907 PYXS shares, 5.42% of the class, as of 2026-10-01, in a 13G filed 2026-10-05. 0001104659-26-113597

    Accepted , ingested

  • GordonMD Global Investments LP and 3 other reporting persons reported 27,988,714 PYXS shares, 17.5% of the class, as of 2026-10-01, in a 13G/A filed 2026-10-02. 0000919574-26-006608

    Accepted , ingested