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Disclosery

PYXS PYXIS ONCOLOGY INC

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Stock (common), issuer CIK 1782223

76 managers (78 13F filers) reported a position in PYXS shares at 2026-03-31, 27,569,875 shares in all. 11 filers opened a position and 14 filers sold out during the quarter.

Managers
76
13F filers
78
New
11
Added
11
Reduced
36
Sold out
14
Shares held by filers
27,569,875

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

Each filer's latest stake. The shares are the aggregate the reporting persons state, which can include entities that file no 13F.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2026

Filers in the available 13F reports with a share position at 2026-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Pfizer Inc7,032,770$9.21M3.86%013F-HRTimeline
Laurion Capital Management LP4,997,333$7.3M0.68%+200,85413F-HRTimeline
GordonMD Global Investments LPin group GordonMD Global Investments LP4,121,870$6.02M4.19%013F-HRTimelineGroup
VANGUARD GROUP INCgroup of 3 filers holding2,355,649$3.44MnewTimeline
Atle Fund Management AB197,036$1.62M0.52%-420,20913F-HRTimeline
Palo Alto Investors LP1,010,510$1.48M0.23%-26,91113F-HRTimeline
683 Capital Management, LLCin group 683 Capital Management, LLC896,263$1.31M0.12%+4,35313F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC888,680$1.3M<0.01%+160,30013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.788,839$1.15M<0.01%+4,76213F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC598,121$874K<0.01%+20,91013F-HRTimelineGroup
Longaeva Partners L.P.503,214$735K0.04%013F-HRTimeline
JACOBS LEVY EQUITY MANAGEMENT, INC460,997$673K<0.01%new13F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC397,625$581K<0.01%-345,48213F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP354,417$517K<0.01%-35,34713F-HRTimelineGroup
Decheng Capital LLC326,810$477K0.07%013F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC304,459$445K<0.01%-481,55113F-HRTimelineGroup
UBS Group AGin group UBS Group AG254,124$371K<0.01%-138,64213F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP248,837$363K<0.01%+7,20013F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd200,096$292K0.01%-88,93713F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC144,256$209K<0.01%new13F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp133,996$196K<0.01%-31,04813F-HRTimelineGroup
NewEdge Wealth, LLC116,006$169K<0.01%013F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP101,948$149K<0.01%013F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC81,260$119K<0.01%+8,56013F-HRTimeline
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP73,300$107K<0.01%-32,22813F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY69,688$102K<0.01%-19,53413F-HRTimelineGroup
PANAGORA ASSET MANAGEMENT INC69,424$101K<0.01%new13F-HRTimeline
Cable Car Capital, LP61,606$89.9K0.03%013F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC61,249$89.4K<0.01%-182,34013F-HRTimelineGroup
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP50,537$73.8K<0.01%new13F-HRTimelineGroup
TORONTO DOMINION BANKin group TORONTO DOMINION BANK50,000$73K<0.01%-25,00013F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC49,825$72.7K<0.01%-10,56013F-HRTimelineGroup
UNIVERSITY OF CHICAGO48,731$71.1K0.02%013F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC46,920$68.5K<0.01%-39,22513F-HRTimelineGroup
J. Derek Lewis & Associates Inc.43,000$62.8K0.01%-10,00013F-HR/ATimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…41,201$60.2K<0.01%-67,21313F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC34,755$50.7K<0.01%-5,00013F-HRTimeline
LPL Financial LLC33,554$49K<0.01%-1,54813F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.32,006$46.7K<0.01%-156,13013F-HRTimelineGroup
Cetera Investment Advisers27,260$39.8K<0.01%013F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP25,912$37.8K<0.01%-24,15413F-HRTimelineGroup
Graham Capital Management, L.P.22,748$33.2K<0.01%-161,19413F-HRTimeline
Maia Wealth LLC21,277$31.1K0.01%-68213F-HRTimeline
Catalyst Funds Management Pty Ltd20,400$29.8K0.01%new13F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC17,537$25.6K<0.01%new13F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/16,807$24.5K<0.01%-571,04413F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.13,721$20K<0.01%-3,50313F-HRTimelineGroup
TWO SIGMA SECURITIES, LLC13,474$19.7K<0.01%new13F-HRTimeline
FMR LLCin group FMR LLC11,912$17.4K<0.01%-94613F-HRTimelineGroup
PACES FERRY WEALTH ADVISORS, LLC11,440$16.7K0.01%013F-HRTimeline
Qube Research & Technologies Ltd11,286$16.5K<0.01%-134,52713F-HRTimeline
China Universal Asset Management Co., L…11,049$16.1K<0.01%+90313F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…10,332$15.1K<0.01%-47813F-HRTimelineGroup
NewEdge Advisors, LLC10,250$15K<0.01%013F-HR/ATimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…6,500$9.49K<0.01%new13F-HRTimelineGroup
Winthrop Capital Management, LLC6,000$9K<0.01%013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA5,839$9K<0.01%-49,71213F-HRTimelineGroup
HAGER INVESTMENT MANAGEMENT SERVICES, L…5,000$7.3K<0.01%new13F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO5,173$6.57K<0.01%-34113F-HR/ATimelineGroup
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…3,248$4.74K<0.01%+22213F-HR/ATimelineGroup
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.3,181$4.64K<0.01%+1,28713F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC1,740$2.54K<0.01%-1,16213F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS1,654$2.42K<0.01%-22,62513F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.1,316$1.92K<0.01%+3913F-HRTimeline
NISA INVESTMENT ADVISORS, LLC961$1.4K<0.01%013F-HRTimeline
Physician Wealth Advisors, Inc.943$1.38K<0.01%013F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management743$1.08K<0.01%-7,48413F-HRTimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP500$655<0.01%013F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN285$416<0.01%-2,00013F-HR/ATimelineGroup
SIMPLEX TRADING, LLC253$369<0.01%-9,53713F-HRTimeline
Cornerstone Financial Management LLC172$251<0.01%013F-HR/ATimeline
CWM, LLCin group CWM, LLC34$50<0.01%-3613F-HRTimelineGroup
Arax Advisory Partners1$20<0.01%-1313F-HRTimeline
Ascentis Independent Advisorsin group Ascentis Wealth Management, L…10$14<0.01%new13F-HRTimelineGroup
Caitong International Asset Management …4$6<0.01%new13F-HRTimeline
SBI Securities Co., Ltd.1$1<0.01%013F-HRTimeline

Events

  • GordonMD Global Investments LP and 3 other reporting persons reported 20,441,948 PYXS shares, 16.4% of the class, as of 2026-10-01, in a 13G/A filed 2026-10-09. 0000919574-26-006818

    Accepted , ingested

  • Coastlands Capital LP and 4 other reporting persons reported 6,448,907 PYXS shares, 5.42% of the class, as of 2026-10-01, in a 13G filed 2026-10-05. 0001104659-26-113597

    Accepted , ingested

  • GordonMD Global Investments LP and 3 other reporting persons reported 27,988,714 PYXS shares, 17.5% of the class, as of 2026-10-01, in a 13G/A filed 2026-10-02. 0000919574-26-006608

    Accepted , ingested