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Disclosery

PYXS PYXIS ONCOLOGY INC

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Stock (common), issuer CIK 1782223

75 managers (75 13F filers) reported a position in PYXS shares at 2025-06-30, 27,457,801 shares in all. 15 filers opened a position and 30 filers sold out during the quarter.

Managers
75
13F filers
75
New
15
Added
20
Reduced
24
Sold out
30
Shares held by filers
27,457,801

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

Each filer's latest stake. The shares are the aggregate the reporting persons state, which can include entities that file no 13F.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2025

Filers in the available 13F reports with a share position at 2025-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Pfizer Inc7,032,770$7.74M1.34%013F-HRTimeline
Laurion Capital Management LP3,625,974$3.99M0.46%013F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC3,539,860$3.89M<0.01%+1,054,58413F-HRTimelineGroup
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC2,500,000$2.75M0.14%+1,400,00013F-HRTimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding2,149,396$2.36M-300,319Timeline
Palo Alto Investors LP1,037,421$1.14M0.24%013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.926,805$1.02M<0.01%-2,345,16913F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc913,045$1M<0.01%013F-HRTimelineGroup
683 Capital Management, LLCin group 683 Capital Management, LLC545,000$600K0.06%-5,00013F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC510,963$562K<0.01%-598,13513F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC417,822$460K<0.01%-164,31413F-HRTimeline
UBS Group AGin group UBS Group AG396,096$436K<0.01%-74813F-HRTimelineGroup
PIER 88 INVESTMENT PARTNERS LLC367,170$404K0.08%-23,79013F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC336,084$370K<0.01%new13F-HRTimelineGroup
Decheng Capital LLC326,810$359K0.09%013F-HRTimeline
SCHULHOFF & CO INC275,000$302K0.13%+153,00013F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC224,274$247K<0.01%+63,44413F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP186,055$205K<0.01%-746,14313F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp165,044$182K<0.01%-107,72513F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY160,174$176K<0.01%-286,30813F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP147,771$163K<0.01%new13F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC142,295$157K<0.01%+61,50013F-HRTimeline
Y-Intercept (Hong Kong) Ltd133,047$146K<0.01%new13F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…114,359$126K<0.01%+49,47113F-HRTimelineGroup
NewEdge Wealth, LLC116,006$124K<0.01%013F-HRTimeline
Qube Research & Technologies Ltd103,063$113K<0.01%+57,93513F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP102,216$112K<0.01%-271,50013F-HRTimelineGroup
FMR LLCin group FMR LLC94,846$104K<0.01%+8,19113F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC86,763$95.4K<0.01%+46,49313F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA86,365$95K<0.01%-10,29413F-HR/ATimelineGroup
Cable Car Capital, LP61,606$67.8K0.03%013F-HR/ATimeline
COMMONWEALTH EQUITY SERVICES, LLC61,155$67K<0.01%+17,90513F-HRTimeline
HRT FINANCIAL LP50,668$55K<0.01%new13F-HRTimeline
UNIVERSITY OF CHICAGO48,731$53.6K0.05%013F-HRTimeline
Jain Global LLC48,649$53.5K<0.01%new13F-HRTimeline
Velan Capital Investment Management LP40,000$44K0.04%new13F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP36,516$40.2K<0.01%013F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd36,380$40K<0.01%new13F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC35,428$39K<0.01%+20,51413F-HR/ATimelineGroup
Cetera Investment Advisers28,760$31.6K<0.01%+90013F-HRTimeline
Catalyst Funds Management Pty Ltd23,200$25.5K0.01%new13F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/22,069$24.3K<0.01%-18,25413F-HRTimelineGroup
Point72 Asia (Singapore) Pte. Ltd.19,228$21.2K<0.01%new13F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC18,942$20K<0.01%-65,18013F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.17,721$19.5K<0.01%-4,65813F-HR/ATimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…14,657$16.1K<0.01%+3,49913F-HRTimelineGroup
LPL Financial LLC14,199$15.6K<0.01%-1,90013F-HRTimeline
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…13,790$15.2K<0.01%new13F-HR/ATimelineGroup
DRW Securities, LLC13,042$14.3K<0.01%new13F-HRTimeline
China Universal Asset Management Co., L…12,442$13.7K<0.01%+51413F-HRTimeline
Quadrature Capital Ltdin group Quadrature Capital Ltd12,334$13.6K<0.01%new13F-HRTimelineGroup
SIMPLEX TRADING, LLC12,615$13K<0.01%+3,81013F-HRTimeline
MERCER GLOBAL ADVISORS INC /ADV10,004$11K<0.01%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC8,927$9.82K<0.01%-26,11313F-HRTimelineGroup
CWM, LLCin group CWM, LLC6,536$7K<0.01%+3,15013F-HRTimelineGroup
Winthrop Capital Management, LLC6,000$7K<0.01%013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC4,854$5.34K<0.01%-49,25513F-HR/ATimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC3,231$3.55K<0.01%new13F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding2,393$2.63K-28,856Timeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO2,068$2.27K<0.01%-26,06713F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS1,833$2.02K<0.01%-1,83413F-HRTimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP1,500$1.65K<0.01%013F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.1,429$1.57K<0.01%013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC961$1.06K<0.01%+66113F-HRTimeline
Physician Wealth Advisors, Inc.943$1.04K<0.01%new13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN699$769<0.01%-29,19113F-HRTimelineGroup
GROUP ONE TRADING LLC602$662<0.01%-2,40813F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…591$650<0.01%+10713F-HRTimelineGroup
True Wealth Design, LLC276$304<0.01%+26913F-HRTimeline
NewEdge Advisors, LLC250$275<0.01%013F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…64$70<0.01%013F-HRTimelineGroup
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…12$13<0.01%013F-HRTimelineGroup
SBI Securities Co., Ltd.1$1<0.01%-113F-HRTimeline
Caitong International Asset Management …1$1<0.01%-213F-HRTimeline
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.

Events

  • GordonMD Global Investments LP and 3 other reporting persons reported 20,441,948 PYXS shares, 16.4% of the class, as of 2026-10-01, in a 13G/A filed 2026-10-09. 0000919574-26-006818

    Accepted , ingested

  • Coastlands Capital LP and 4 other reporting persons reported 6,448,907 PYXS shares, 5.42% of the class, as of 2026-10-01, in a 13G filed 2026-10-05. 0001104659-26-113597

    Accepted , ingested

  • GordonMD Global Investments LP and 3 other reporting persons reported 27,988,714 PYXS shares, 17.5% of the class, as of 2026-10-01, in a 13G/A filed 2026-10-02. 0000919574-26-006608

    Accepted , ingested