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Disclosery

LXRX LEXICON PHARMACEUTICALS INC

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COMMON STOCK (common), issuer CIK 1062822

133 managers (137 13F filers) reported a position in LXRX shares at 2026-03-31, 323,381,236 shares in all. 25 filers opened a position and 15 filers sold out during the quarter.

Managers
133
13F filers
137
New
25
Added
41
Reduced
26
Sold out
15
Shares held by filers
323,381,236

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2026

Filers in the available 13F reports with a share position at 2026-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Artal Group S.A.in group Artal Group S.A.154,734,327$241M23.89%+18,553,84613F-HRTimelineGroup
FMR LLCin group FMR LLC45,056,338$70.3M<0.01%+7,222,13113F-HRTimelineGroup
Siren, L.L.C.in group Siren, L.L.C.44,303,518$69.1M1.92%+5,384,61513F-HRTimelineGroup
Sessa Capital IM, L.P.17,912,961$27.9M0.53%+14,912,96113F-HRTimeline
VANGUARD GROUP INCgroup of 5 filers holding11,546,657$18M+11,480,090Timeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.7,814,606$12.2M0.02%+7,530,58113F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC4,944,731$7.71M0.01%+122,99813F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.3,322,219$5.18M<0.01%+129,77113F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC3,169,111$4.95M<0.01%+669,08913F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC2,665,938$4.16M<0.01%+941,63413F-HRTimelineGroup
UBS Group AGin group UBS Group AG2,483,182$3.87M<0.01%-524,05513F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP2,376,304$3.71M<0.01%+1,113,93713F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…2,121,164$3.31M<0.01%+913,92213F-HRTimelineGroup
CIBC Bancorp USA Inc.in group CIBC Bancorp USA Inc.1,800,000$2.81M<0.01%13F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC1,600,500$2.5M<0.01%+1,337,24613F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co1,311,298$2.05M<0.01%+256,17513F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP1,199,632$1.87M<0.01%+562,32413F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC1,094,901$1.71M<0.01%-616,07413F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC1,070,517$1.67M<0.01%+149,31313F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP964,038$1.5M<0.01%+79,30013F-HRTimelineGroup
GSA CAPITAL PARTNERS LLP930,089$1.45M0.09%-66,14613F-HRTimeline
Ishara Investments LP902,000$1.41M1.42%+22,00013F-HRTimeline
Hennion & Walsh Asset Management, Inc.848,138$1.32M0.04%-53,08413F-HRTimeline
MACKENZIE FINANCIAL CORP772,677$1.21M<0.01%new13F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC750,000$1.17M0.07%new13F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/526,103$821K<0.01%+424,00613F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.512,426$799K<0.01%-82,45713F-HRTimelineGroup
Compagnie Lombard Odier SCmA510,000$796K0.01%+100,00013F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP494,666$772K<0.01%+82,50213F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC445,288$693K<0.01%-194,84213F-HRTimelineGroup
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC399,700$624K0.03%new13F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd314,614$491K0.01%+218,52413F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY219,862$343K<0.01%+26,82713F-HRTimelineGroup
Catalyst Funds Management Pty Ltd207,900$324K0.05%+167,60013F-HRTimeline
Headlands Technologies LLC191,322$298K0.03%+55,20913F-HRTimeline
GROUP ONE TRADING LLC185,006$289K0.01%-39,30213F-HRTimeline
CITIGROUP INCin group CITIGROUP INC166,398$260K<0.01%+74,72813F-HRTimelineGroup
Ikarian Capital, LLCin group Ikarian Capital, LLC164,674$257K0.04%013F-HRTimelineGroup
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…160,499$250K<0.01%new13F-HRTimelineGroup
SCOTIA CAPITAL INC.159,831$249K<0.01%new13F-HRTimeline
Jain Global LLC154,800$241K<0.01%new13F-HRTimeline
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…152,616$238K<0.01%+52,08413F-HRTimelineGroup
JACOBS LEVY EQUITY MANAGEMENT, INC130,020$203K<0.01%new13F-HRTimeline
Bridgewater Advisors Inc.82,209$201K0.01%new13F-HRTimeline
HRT FINANCIAL LP122,780$191K<0.01%+5,23113F-HRTimeline
Cerity Partners LLCin group Cerity Partners LLC110,458$172K<0.01%-34,48613F-HRTimelineGroup
Quadrature Capital Ltdin group Quadrature Capital Ltd110,379$172K<0.01%+91,96513F-HRTimelineGroup
Quarry LP110,000$172K0.03%+22,00013F-HRTimeline
Man Group plcin group Man Group plc108,806$170K<0.01%new13F-HRTimelineGroup
OMERS ADMINISTRATION Corp106,800$167K<0.01%-167,00013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC105,487$165K<0.01%-89,25613F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC96,234$150K<0.01%-48,56613F-HRTimelineGroup
Schonfeld Strategic Advisors LLC75,110$117K<0.01%+62,00213F-HRTimeline
BANK OF NOVA SCOTIAin group BANK OF NOVA SCOTIA73,707$115K<0.01%new13F-HRTimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/70,000$109K<0.01%013F-HRTimelineGroup
LPL Financial LLC69,783$109K<0.01%-17,27413F-HRTimeline
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.68,734$107K<0.01%-23,79613F-HRTimelineGroup
Diametric Capital, LP67,841$106K0.03%new13F-HRTimeline
R Squared Ltd67,526$105K0.06%+20,94713F-HRTimeline
Straight Path Wealth Management62,666$97.8K0.03%013F-HRTimeline
Fortis Group Advisors, LLC50,000$80.5K0.01%013F-HRTimeline
EntryPoint Capital, LLC48,498$75.7K0.02%+14,88013F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC44,315$69.1K<0.01%013F-HRTimeline
WEDBUSH SECURITIES INC40,850$64K<0.01%013F-HRTimeline
Jump Financial, LLCin group Jump Financial, LLC40,246$62.8K<0.01%new13F-HRTimelineGroup
CIBC Asset Management Inc39,520$61.7K<0.01%013F-HRTimeline
ExodusPoint Capital Management, LP37,430$58.4K<0.01%-231,00313F-HRTimeline
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT…35,714$55.7K0.01%013F-HRTimeline
Graham Capital Management, L.P.34,027$53.1K<0.01%-75,87313F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC33,800$52.7K<0.01%013F-HRTimelineGroup
Leonteq Securities AG30,000$46.8K<0.01%013F-HRTimeline
KWB Wealth40,640$46.7K<0.01%013F-HRTimeline
Pathstone Holdings, LLCin group Pathstone Holdings, LLC29,774$46.4K<0.01%-19513F-HRTimelineGroup
PINNACLE ASSOCIATES LTD29,015$45.3K<0.01%013F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp27,459$42.8K<0.01%+8,33513F-HRTimelineGroup
SECURITY NATIONAL BANK OF SIOUX CITY IO…26,650$41.6K0.02%013F-HRTimeline
WINTON GROUP Ltdin group WINTON GROUP Ltd25,500$39.8K<0.01%new13F-HRTimelineGroup
OPPENHEIMER & CO INCin group OPPENHEIMER ASSET MANAGEMENT …23,500$36.7K<0.01%013F-HRTimelineGroup
LMR Partners LLPin group LMR Partners LLP23,305$36.4K<0.01%new13F-HRTimelineGroup
VICTORY CAPITAL MANAGEMENT INC22,679$35.4K<0.01%+1,48813F-HRTimeline
Cambridge Investment Research Advisors,…21,505$34K<0.01%013F-HRTimeline
AXQ CAPITAL, LP20,150$31.4K<0.01%new13F-HRTimeline
DIKER MANAGEMENT LLCin group DIKER MANAGEMENT LLC20,000$31.2K0.03%new13F-HRTimelineGroup
Invera Wealth Advisors, LLC20,000$31.2K0.02%013F-HRTimeline
TIAAgroup of 2 filers holding20,000$31.2K0Timeline
CREDIT AGRICOLE S Ain group CREDIT AGRICOLE S A18,975$29.6K<0.01%013F-HRTimelineGroup
Quantessence Capital LLC18,581$29K0.14%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS17,550$27.4K<0.01%+17,53913F-HRTimelineGroup
CTC Alternative Strategies, Ltd.17,544$27.4K0.06%new13F-HRTimeline
PRELUDE CAPITAL MANAGEMENT, LLC17,173$26.8K<0.01%new13F-HRTimeline
CAPTRUST FINANCIAL ADVISORS15,450$24.1K<0.01%+3,71513F-HRTimeline
HBK Sorce Advisory LLC11,786$23.6K<0.01%013F-HRTimeline
Callan Family Office, LLCin group Callan Family Office, LLC14,090$22K<0.01%013F-HRTimelineGroup
TRUIST FINANCIAL CORPin group TRUIST FINANCIAL CORP14,000$21.8K<0.01%013F-HRTimelineGroup
Cetera Investment Advisers12,633$19.7K<0.01%-1,55513F-HRTimeline
WEALTH ENHANCEMENT ADVISORY SERVICES, L…12,388$19.7K<0.01%-1,13213F-HRTimeline
Chemistry Wealth Management LLC12,000$18.7K<0.01%013F-HRTimeline
FWG Holdings, LLC11,350$18K0.01%013F-HRTimeline
Mariner, LLCin group Mariner, LLC11,072$17.3K<0.01%new13F-HRTimelineGroup
Perennial Investment Advisors, LLC10,990$17.1K<0.01%013F-HRTimeline
State of Wyoming10,779$16.8K<0.01%-49,79213F-HRTimeline
CWM, LLCin group CWM, LLC10,402$16.2K<0.01%-2,77713F-HRTimelineGroup
NBT BANK, N.A.in group NBT BANK, N.A.10,000$15.6K<0.01%013F-HRTimelineGroup
Berger Financial Group, Inc10,000$15.6K<0.01%013F-HRTimeline
Talisman Wealth Advisors LLC10,000$15.6K0.01%new13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN7,760$12.1K<0.01%+7,75913F-HR/ATimelineGroup
SBI Securities Co., Ltd.4,081$6.37K<0.01%+1,06313F-HRTimeline
Advisory Services Network, LLC3,242$5.06K<0.01%new13F-HRTimeline
NISA INVESTMENT ADVISORS, LLC2,592$4.04K<0.01%013F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…1,461$2.28K<0.01%013F-HRTimelineGroup
Physician Wealth Advisors, Inc.1,412$2.2K<0.01%013F-HRTimeline
Rialto Wealth Management, LLC1,313$2.05K<0.01%013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA1,551$2K<0.01%-5,21713F-HRTimelineGroup
Avion Wealth1,333$2K<0.01%013F-HRTimeline
Cassaday & Co Wealth Management LLC1,000$1.56K<0.01%new13F-HRTimeline
Fortitude Family Office, LLC706$1.1K<0.01%013F-HRTimeline
Basecamp Wealth Advisors LLC691$1.08K<0.01%013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.663$1.03K<0.01%+2113F-HRTimelineGroup
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…503$785<0.01%+313F-HRTimelineGroup
Steward Partners Investment Advisory, L…500$780<0.01%013F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP356$587<0.01%-75013F-HRTimelineGroup
Caitong International Asset Management …353$551<0.01%+20613F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…335$523<0.01%013F-HRTimelineGroup
Farther Finance Advisors, LLC255$418<0.01%-2,50013F-HRTimeline
Parallel Advisors, LLC247$385<0.01%new13F-HR/ATimeline
SYNTAX RESEARCH, INC.142$222<0.01%013F-HRTimeline
Larson Financial Group LLC100$156<0.01%013F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…48$75<0.01%-11013F-HR/ATimelineGroup
Arax Advisory Partners41$64<0.01%013F-HRTimeline
HM PAYSON & CO37$58<0.01%new13F-HRTimeline
True Wealth Design, LLC2$4<0.01%-4713F-HRTimeline
RHUMBLINE ADVISERS0$2<0.01%013F-HRTimelineAmount filed as zero, left out of ratios.
Covestor Ltd81$00%013F-HRTimelineValue filed as zero, left out of ratios.