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Disclosery

LKFT LAKEFRONT BIOTHERAPEUTICS NV

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SPON ADR (ADR), issuer CIK 1421876

90 managers (91 13F filers) reported a position in LKFT shares at 2025-12-31, 31,396,161 shares in all. 13 filers opened a position and 16 filers sold out during the quarter.

Managers
90
13F filers
91
New
13
Added
28
Reduced
33
Sold out
16
Shares held by filers
31,396,161

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
GILEAD SCIENCES, INC.in group GILEAD SCIENCES, INC.16,707,477$551M28.45%013F-HRTimelineGroup
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC3,921,219$128M6.33%-229,97513F-HRTimelineGroup
Madison Avenue Partners, LP2,213,169$72.4M3.11%+17,39413F-HRTimeline
EcoR1 Capital, LLC1,667,119$54.5M2.49%013F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC1,451,239$47.5M0.01%+34,30513F-HRTimelineGroup
Prosight Management, LP1,074,112$35.1M7.26%-75,88813F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.486,209$15.9M0.02%+42,34013F-HRTimelineGroup
DME Capital Management, LPin group DME Capital Management, LP482,746$15.8M0.55%013F-HRTimelineGroup
SEGALL BRYANT & HAMILL, LLC448,096$14.7M0.2%-39,10013F-HRTimeline
UBS Group AGin group UBS Group AG349,444$11.4M<0.01%+196,44513F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC339,354$11.1M0.01%+186,45213F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.314,269$10.3M<0.01%+74,42613F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC310,600$10.2M0.02%-45,60013F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.274,999$8.99M0.01%+73,83013F-HRTimelineGroup
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…170,000$5.56M0.03%-75,00013F-HRTimelineGroup
DAFNA Capital Management LLC130,175$4.26M0.99%013F-HRTimeline
NORGES BANK90,000$2.94M<0.01%new13F-HRTimeline
KOTLER KEVIN90,000$2.94M2.17%13F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC89,396$2.92M<0.01%+73,42713F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY68,285$2.23M<0.01%+4,22213F-HR/ATimelineGroup
FMR LLCin group FMR LLC56,969$1.86M<0.01%+2,95813F-HRTimelineGroup
ALPS ADVISORS INCin group ALPS ADVISORS INC53,791$1.76M0.01%+21,88613F-HRTimelineGroup
Man Group plcin group Man Group plc47,581$1.56M<0.01%+11,38413F-HRTimelineGroup
VOLORIDGE INVESTMENT MANAGEMENT, LLC43,856$1.43M0.01%-43,71613F-HRTimeline
Massar Capital Management, LP39,000$1.28M0.25%new13F-HRTimeline
Crossmark Global Holdings, Inc.32,977$1.08M0.02%+8013F-HRTimeline
Monaco Asset Management SAM32,520$1.06M0.32%-1,01613F-HRTimeline
Western Standard LLC32,000$1.05M0.48%new13F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/30,969$1.01M<0.01%+2013F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC29,000$948K0.01%-22,30013F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding27,660$904K-3,499Timeline
BAROMETER CAPITAL MANAGEMENT INC.37,100$884K0.21%+9,48313F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC26,729$874K<0.01%-87413F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd23,219$759K0.02%+11,16213F-HRTimelineGroup
MOODY NATIONAL BANK TRUST DIVISIONin group MOODY NATIONAL BANK TRUST DIV…20,849$682K0.07%013F-HRTimelineGroup
PRELUDE CAPITAL MANAGEMENT, LLC19,305$631K0.05%-2213F-HRTimeline
QRG CAPITAL MANAGEMENT, INC.16,170$529K0.01%+1,07713F-HRTimeline
Quadrature Capital Ltdin group Quadrature Capital Ltd15,006$491K0.01%-11,23913F-HRTimelineGroup
Erste Asset Management GmbHin group Erste Asset Management GmbH14,000$464K<0.01%013F-HRTimelineGroup
Aquatic Capital Management LLC13,712$448K0.01%-3,80413F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP11,200$366K<0.01%-27,26013F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC11,144$364K<0.01%-54,99713F-HR/ATimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS11,098$363K<0.01%-75613F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC8,861$290K<0.01%+1313F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC7,851$257K<0.01%013F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC7,541$246K<0.01%new13F-HRTimelineGroup
RHUMBLINE ADVISERS6,972$228K<0.01%+3,37213F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…6,968$228K<0.01%new13F-HRTimelineGroup
Ascent Group, LLCin group Ascent Group, LLC6,237$204K0.01%-7613F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA5,355$175K<0.01%-23,07413F-HRTimelineGroup
QUADRANT CAPITAL GROUP LLC3,520$115K<0.01%-36013F-HRTimeline
China Universal Asset Management Co., L…2,356$77K0.01%-15513F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC2,355$77K<0.01%-36,64713F-HRTimelineGroup
Arax Advisory Partners2,335$76.4K<0.01%+1,77813F-HRTimeline
VAN ECK ASSOCIATES CORPin group VAN ECK ASSOCIATES CORP1,968$64K<0.01%+75013F-HRTimelineGroup
SIGNATUREFD, LLC1,641$53.7K<0.01%-19913F-HRTimeline
GAMMA Investing LLC1,250$40.9K<0.01%-22313F-HRTimeline
State of Wyoming1,227$40.1K<0.01%+27113F-HRTimeline
CACTI ASSET MANAGEMENT LLC1,000$33.1K<0.01%013F-HRTimeline
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…702$23K<0.01%+14813F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…548$17.9K<0.01%-4913F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC404$13.2K<0.01%-13,44913F-HRTimelineGroup
Smartleaf Asset Management LLC389$12.7K<0.01%new13F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.370$12.1K<0.01%-25513F-HRTimelineGroup
DV EQUITIES, LLC332$10.9K<0.01%13F-HRTimeline
Larson Financial Group LLC288$9.42K<0.01%+13213F-HRTimeline
GF FUND MANAGEMENT CO. LTD.282$9.22K<0.01%-2313F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…281$9.19K<0.01%013F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO239$7.82K<0.01%+16813F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\182$5.95K<0.01%+8813F-HRTimelineGroup
Farther Finance Advisors, LLC145$4.74K<0.01%+14413F-HRTimeline
Allworth Financial LP139$4.55K<0.01%-4413F-HRTimeline
Parallel Advisors, LLC103$3.37K<0.01%-5013F-HRTimeline
SageView Advisory Group, LLC80$2.62K<0.01%new13F-HRTimeline
SIMPLEX TRADING, LLC74$2.42K<0.01%-18013F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.51$2K<0.01%013F-HRTimelineGroup
MAI Capital Management52$1.7K<0.01%013F-HRTimeline
Crewe Advisors LLC46$1.5K<0.01%013F-HRTimeline
Wilmington Savings Fund Society, FSB36$1.18K<0.01%new13F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…32$1.05K<0.01%-27713F-HRTimelineGroup
BESSEMER GROUP INCin group BESSEMER GROUP INC41$1K<0.01%new13F-HRTimelineGroup
MANNING & NAPIER ADVISORS LLC26$848<0.01%new13F-HRTimeline
TD PRIVATE CLIENT WEALTH LLC24$785<0.01%013F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…22$719<0.01%-413F-HRTimelineGroup
ASSETMARK, INCin group ASSETMARK, INC22$719<0.01%-2013F-HRTimelineGroup
Signature Equity Partners, LLC22$719<0.01%13F-HRTimeline
IMA Advisory Services, Inc.15$490<0.01%new13F-HRTimeline
NewEdge Advisors, LLC6$196<0.01%013F-HRTimeline
HUNTINGTON NATIONAL BANKin group HUNTINGTON NATIONAL BANK4$131<0.01%new13F-HRTimelineGroup
Caitong International Asset Management …4$131<0.01%new13F-HR/ATimeline