GILEAD SCIENCES, INC. in group GILEAD SCIENCES, INC. More: the full row for GILEAD SCIENCES, INC. 16,707,477 $501M 23.67% 0 13F-HR Timeline Group TANG CAPITAL MANAGEMENT LLC in group TANG CAPITAL MANAGEMENT LLC More: the full row for TANG CAPITAL MANAGEMENT LLC 3,785,991 $114M 5.77% -135,228 13F-HR Timeline Group Madison Avenue Partners, LP More: the full row for Madison Avenue Partners, LP 2,465,179 $74M 3.22% +252,010 13F-HR Timeline EcoR1 Capital, LLC More: the full row for EcoR1 Capital, LLC 1,667,119 $50M 2.14% 0 13F-HR Timeline Prosight Management, LP More: the full row for Prosight Management, LP 1,550,000 $46.5M 7.63% +475,888 13F-HR Timeline AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 1,424,674 $42.7M 0.01% -26,565 13F-HR/A Timeline Group DME Capital Management, LP in group DME Capital Management, LP More: the full row for DME Capital Management, LP 482,746 $14.5M 0.45% 0 13F-HR Timeline Group SEGALL BRYANT & HAMILL, LLC More: the full row for SEGALL BRYANT & HAMILL, LLC 426,412 $12.8M 0.18% -21,684 13F-HR/A Timeline Point72 Asset Management, L.P. in group Point72 Asset Management, L.P. More: the full row for Point72 Asset Management, L.P. 332,125 $9.96M 0.02% -154,084 13F-HR Timeline Group RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 315,400 $9.46M 0.01% +4,800 13F-HR Timeline BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 312,106 $9.36M <0.01% -2,163 13F-HR Timeline Group D. E. Shaw & Co., Inc. in group D. E. Shaw & Co., Inc. More: the full row for D. E. Shaw & Co., Inc. 215,718 $6.47M 0.01% -59,281 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 175,289 $5.26M <0.01% -174,155 13F-HR Timeline Group DAFNA Capital Management LLC More: the full row for DAFNA Capital Management LLC 130,175 $3.91M 0.89% 0 13F-HR Timeline CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 124,428 $3.73M <0.01% +35,032 13F-HR Timeline Group MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 107,912 $3.24M <0.01% -231,442 13F-HR Timeline Group OLD MISSION CAPITAL LLC More: the full row for OLD MISSION CAPITAL LLC 95,591 $2.87M 0.07% new 13F-HR Timeline Man Group plc in group Man Group plc More: the full row for Man Group plc 80,209 $2.41M <0.01% +32,628 13F-HR Timeline Group Hudson Bay Capital Management LP in group Hudson Bay Capital Management… More: the full row for Hudson Bay Capital Management LP 77,500 $2.33M 0.01% -92,500 13F-HR Timeline Group Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 66,536 $2M 0.05% +65,988 13F-HR Timeline Group ALPS ADVISORS INC in group ALPS ADVISORS INC More: the full row for ALPS ADVISORS INC 53,661 $1.61M 0.01% -130 13F-HR Timeline Group ACADIAN ASSET MANAGEMENT LLC in group ACADIAN ASSET MANAGEMENT LLC More: the full row for ACADIAN ASSET MANAGEMENT LLC 45,942 $1.37M <0.01% +38,401 13F-HR Timeline Group GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 45,371 $1.36M <0.01% +34,227 13F-HR Timeline Group HRT FINANCIAL LP More: the full row for HRT FINANCIAL LP 45,168 $1.35M <0.01% new 13F-HR Timeline AMERICAN CENTURY COMPANIES INC in group AMERICAN CENTURY COMPANIES INC More: the full row for AMERICAN CENTURY COMPANIES INC 38,790 $1.16M <0.01% +12,061 13F-HR Timeline Group BAROMETER CAPITAL MANAGEMENT INC. More: the full row for BAROMETER CAPITAL MANAGEMENT INC. 38,100 $1.14M 0.39% +1,000 13F-HR Timeline Crossmark Global Holdings, Inc. More: the full row for Crossmark Global Holdings, Inc. 32,607 $978K 0.01% -370 13F-HR Timeline Monaco Asset Management SAM More: the full row for Monaco Asset Management SAM 27,520 $826K 0.26% -5,000 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 26,619 $799K <0.01% -41,666 13F-HR Timeline Group Optiver Holding B.V. in group Optiver Holding B.V. More: the full row for Optiver Holding B.V. 26,535 $796K 0.03% new 13F-HR/A Timeline Group TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 25,860 $776K <0.01% +9,500 13F-HR Timeline Group XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 25,404 $762K 0.01% +2,185 13F-HR Timeline Group MOODY NATIONAL BANK TRUST DIVISION in group MOODY NATIONAL BANK TRUST DIV… More: the full row for MOODY NATIONAL BANK TRUST DIVISION 20,849 $625K 0.06% 0 13F-HR Timeline Group BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 20,725 $622K <0.01% -10,244 13F-HR Timeline Group QRG CAPITAL MANAGEMENT, INC. More: the full row for QRG CAPITAL MANAGEMENT, INC. 19,705 $591K 0.01% +3,535 13F-HR Timeline PRELUDE CAPITAL MANAGEMENT, LLC More: the full row for PRELUDE CAPITAL MANAGEMENT, LLC 19,305 $579K 0.04% 0 13F-HR Timeline JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 13,607 $408K <0.01% new 13F-HR Timeline Group VOLORIDGE INVESTMENT MANAGEMENT, LLC More: the full row for VOLORIDGE INVESTMENT MANAGEMENT, LLC 13,505 $405K <0.01% -30,351 13F-HR Timeline Erste Asset Management GmbH in group Erste Asset Management GmbH More: the full row for Erste Asset Management GmbH 14,000 $404K <0.01% 0 13F-HR Timeline Group SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 13,387 $402K <0.01% +6,419 13F-HR Timeline Group Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 12,952 $389K <0.01% new 13F-HR Timeline Group ABC ARBITRAGE SA in group ABC ARBITRAGE SA More: the full row for ABC ARBITRAGE SA 12,744 $382K 0.05% new 13F-HR Timeline Group Aquatic Capital Management LLC More: the full row for Aquatic Capital Management LLC 11,859 $356K 0.01% -1,853 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 11,292 $339K <0.01% +194 13F-HR Timeline Group denkapparat Operations GmbH More: the full row for denkapparat Operations GmbH 10,636 $319K 0.13% new 13F-HR Timeline COMMONWEALTH EQUITY SERVICES, LLC More: the full row for COMMONWEALTH EQUITY SERVICES, LLC 10,499 $315K <0.01% +1,638 13F-HR Timeline Cerity Partners LLC in group Cerity Partners LLC More: the full row for Cerity Partners LLC 10,310 $309K <0.01% new 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 10,150 $304K <0.01% +2,299 13F-HR Timeline Group COMMONWEALTH OF PENNSYLVANIA PUBLIC SCH… More: the full row for COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS 8,273 $248K <0.01% new 13F-HR Timeline Orion Porfolio Solutions, LLC More: the full row for Orion Porfolio Solutions, LLC 7,426 $223K <0.01% new 13F-HR Timeline RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 7,381 $221K <0.01% +409 13F-HR Timeline SIMPLEX TRADING, LLC More: the full row for SIMPLEX TRADING, LLC 7,227 $217K 0.01% +7,153 13F-HR Timeline AXQ CAPITAL, LP More: the full row for AXQ CAPITAL, LP 6,777 $203K 0.03% new 13F-HR Timeline GROUP ONE TRADING LLC More: the full row for GROUP ONE TRADING LLC 5,082 $152K 0.01% new 13F-HR Timeline QUADRANT CAPITAL GROUP LLC More: the full row for QUADRANT CAPITAL GROUP LLC 3,653 $110K <0.01% +133 13F-HR/A Timeline China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 2,631 $78.9K 0.01% +275 13F-HR Timeline VAN ECK ASSOCIATES CORP in group VAN ECK ASSOCIATES CORP More: the full row for VAN ECK ASSOCIATES CORP 2,153 $65K <0.01% +185 13F-HR Timeline Group GAMMA Investing LLC More: the full row for GAMMA Investing LLC 2,005 $60.1K <0.01% +755 13F-HR Timeline SIGNATUREFD, LLC More: the full row for SIGNATUREFD, LLC 1,611 $48.3K <0.01% -30 13F-HR Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 1,200 $36K <0.01% new 13F-HR/A Timeline Group CACTI ASSET MANAGEMENT LLC More: the full row for CACTI ASSET MANAGEMENT LLC 1,000 $30K <0.01% 0 13F-HR Timeline State of Wyoming More: the full row for State of Wyoming 991 $29.7K <0.01% -236 13F-HR Timeline Arax Advisory Partners More: the full row for Arax Advisory Partners 874 $26.2K <0.01% -1,461 13F-HR Timeline ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 672 $20K <0.01% -4,683 13F-HR Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 498 $14.9K <0.01% +94 13F-HR Timeline Group OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 483 $14.5K <0.01% +113 13F-HR Timeline Group EverSource Wealth Advisors, LLC in group EverSource Wealth Advisors, L… More: the full row for EverSource Wealth Advisors, LLC 441 $13.2K <0.01% +409 13F-HR/A Timeline Group Smartleaf Asset Management LLC More: the full row for Smartleaf Asset Management LLC 360 $10.4K <0.01% -29 13F-HR Timeline GF FUND MANAGEMENT CO. LTD. More: the full row for GF FUND MANAGEMENT CO. LTD. 318 $9.54K <0.01% +36 13F-HR Timeline Larson Financial Group LLC More: the full row for Larson Financial Group LLC 286 $8.58K <0.01% -2 13F-HR Timeline Farther Finance Advisors, LLC More: the full row for Farther Finance Advisors, LLC 274 $8.15K <0.01% +129 13F-HR Timeline BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 178 $5.34K <0.01% -2,177 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 150 $4.33K <0.01% -89 13F-HR/A Timeline Group US BANCORP \DE\ in group US BANCORP \DE\ More: the full row for US BANCORP \DE\ 144 $4.32K <0.01% -38 13F-HR Timeline Group Allworth Financial LP More: the full row for Allworth Financial LP 137 $4.11K <0.01% -2 13F-HR Timeline Parallel Advisors, LLC More: the full row for Parallel Advisors, LLC 103 $3.09K <0.01% 0 13F-HR/A Timeline BESSEMER GROUP INC in group BESSEMER GROUP INC More: the full row for BESSEMER GROUP INC 102 $3K <0.01% +61 13F-HR Timeline Group MAI Capital Management More: the full row for MAI Capital Management 70 $2.1K <0.01% +18 13F-HR Timeline TD PRIVATE CLIENT WEALTH LLC More: the full row for TD PRIVATE CLIENT WEALTH LLC 61 $1.83K <0.01% +37 13F-HR Timeline Wilmington Savings Fund Society, FSB More: the full row for Wilmington Savings Fund Society, FSB 36 $1.08K <0.01% 0 13F-HR Timeline ASSETMARK, INC in group ASSETMARK, INC More: the full row for ASSETMARK, INC 25 $750 <0.01% +3 13F-HR Timeline Group MANNING & NAPIER ADVISORS LLC More: the full row for MANNING & NAPIER ADVISORS LLC 25 $721 <0.01% -1 13F-HR Timeline Signature Equity Partners, LLC More: the full row for Signature Equity Partners, LLC 23 $690 <0.01% +1 13F-HR Timeline PNC Financial Services Group, Inc. in group PNC Financial Services Group,… More: the full row for PNC Financial Services Group, Inc. 22 $660 <0.01% 0 13F-HR Timeline Group IMA Advisory Services, Inc. More: the full row for IMA Advisory Services, Inc. 15 $450 <0.01% 0 13F-HR Timeline Retirement Wealth Solutions LLC More: the full row for Retirement Wealth Solutions LLC 12 $360 <0.01% new 13F-HR Timeline Tidemark, LLC More: the full row for Tidemark, LLC 10 $300 <0.01% new 13F-HR Timeline NewEdge Advisors, LLC More: the full row for NewEdge Advisors, LLC 6 $180 <0.01% 0 13F-HR/A Timeline CWM, LLC in group CWM, LLC More: the full row for CWM, LLC 3 $90 <0.01% new 13F-HR Timeline Group FMR LLC in group FMR LLC More: the full row for FMR LLC 1 $30 <0.01% -56,968 13F-HR Timeline Group