Skip to content
Disclosery

IONS IONIS PHARMACEUTICALS INC

Follow

Stock (common), issuer CIK 874015

486 managers (498 13F filers) reported a position in IONS shares at 2026-03-31, 172,601,809 shares in all. 63 filers opened a position and 66 filers sold out during the quarter.

Managers
486
13F filers
498
New
63
Added
179
Reduced
158
Sold out
66
Shares held by filers
172,601,809

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2026

Filers in the available 13F reports with a share position at 2026-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/26,585$2M<0.01%-9,77713F-HRTimelineGroup
STEMPOINT CAPITAL LP26,385$1.98M0.38%new13F-HR/ATimeline
XPONANCE LLC26,384$1.98M0.01%+3,44313F-HRTimeline
PROFUND ADVISORS LLC26,287$1.97M0.07%-38613F-HRTimeline
Jain Global LLC26,285$1.97M0.03%-329,97413F-HRTimeline
FLORIDA FINANCIAL ADVISORS, LLC25,886$1.94M0.47%new13F-HRTimeline
Qsemble Capital Management, LP25,758$1.93M0.15%-1,82113F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP26,723$1.93M<0.01%+20,24013F-HRTimelineGroup
LAZARD ASSET MANAGEMENT LLCin group LAZARD ASSET MANAGEMENT LLC25,410$1.91M<0.01%-20,99213F-HRTimelineGroup
TEACHERS RETIREMENT SYSTEM OF THE STATE…24,083$1.81M0.01%013F-HRTimeline
Man Group plcin group Man Group plc24,013$1.8M<0.01%-142,02913F-HRTimelineGroup
Amundiin group Amundi23,958$1.8M<0.01%-436,98913F-HRTimelineGroup
Natixis Investment Managersgroup of 2 filers holding23,721$1.78M-4,257Timeline
Voleon Capital Management LP23,047$1.73M0.04%+18,75913F-HRTimeline
WOLVERINE ASSET MANAGEMENT LLCin group WOLVERINE ASSET MANAGEMENT LLC22,815$1.71M0.03%-7,70013F-HRTimelineGroup
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co22,135$1.67M<0.01%+1,24113F-HRTimelineGroup
Informed Momentum Co LLC20,608$1.55M0.18%-33,30613F-HRTimeline
ALLSTATE CORPin group ALLSTATE CORP20,565$1.54M0.02%new13F-HRTimelineGroup
READYSTATE ASSET MANAGEMENT LP20,436$1.53M0.09%new13F-HRTimeline
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.in group LANDSCAPE CAPITAL MANAGEMENT,…20,146$1.51M0.1%-4,00913F-HRTimelineGroup
Legato Capital Management LLC19,840$1.49M0.14%+13,68513F-HRTimeline
Calamos Advisors LLCin group Calamos Advisors LLC19,781$1.49M0.01%-13,40813F-HRTimelineGroup
FORA Capital, LLC19,693$1.48M0.11%new13F-HRTimeline
Nicollet Investment Management, Inc.19,646$1.48M0.51%-87713F-HRTimeline
AlphaCentric Advisors LLC19,587$1.47M1.47%+1,06413F-HRTimeline
DNB Asset Management ASin group DNB Asset Management AS19,060$1.43M0.01%+4,22213F-HRTimelineGroup
Dana Investment Advisors, Inc.18,487$1.39M0.04%+46113F-HRTimeline
INCEPTIONR LLC16,821$1.26M0.3%-1,02913F-HRTimeline
NORTH STAR ASSET MANAGEMENT INC16,610$1.25M0.05%013F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…15,589$1.17M<0.01%013F-HRTimeline
Caption Management, LLC15,591$1.17M0.06%new13F-HRTimeline
BROWN ADVISORY INCin group BROWN ADVISORY INC15,105$1.13M<0.01%+14013F-HRTimelineGroup
LMR Partners LLPin group LMR Partners LLP15,000$1.13M0.01%013F-HRTimelineGroup
M&G PLCin group M&G PLC14,423$1.08M0.01%013F-HRTimelineGroup
IQ EQ FUND MANAGEMENT (IRELAND) Ltd14,389$1.08M0.08%-77913F-HRTimeline
Bleakley Financial Group, LLC14,316$1.07M0.02%+44113F-HRTimeline
CANADA PENSION PLAN INVESTMENT BOARD14,100$1.06M<0.01%new13F-HRTimeline
Dynasty Wealth Management, LLC14,080$1.06M0.01%+9013F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…13,545$1.02M<0.01%-27113F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding13,302$988K+702Timeline
Westmount Partners, LLC12,961$973K0.24%013F-HRTimeline
TRUIST FINANCIAL CORPin group TRUIST FINANCIAL CORP12,846$965K<0.01%+18713F-HRTimelineGroup
HIGHLAND CAPITAL MANAGEMENT, LLC12,819$963K0.05%new13F-HRTimeline
Annis Gardner Whiting Capital Advisors,…12,801$961K0.15%013F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE12,601$946K<0.01%-4,11513F-HRTimelineGroup
SBI Okasan Asset Management Co.Ltd.12,600$914K0.04%013F-HRTimeline
AMALGAMATED BANK12,054$905K0.01%-40113F-HRTimeline
OPPENHEIMER ASSET MANAGEMENT INC.in group OPPENHEIMER ASSET MANAGEMENT …11,853$890K0.01%+58913F-HRTimelineGroup
Summit Trail Advisors, LLC11,549$867K0.01%+1,60613F-HRTimeline
HORIZON KINETICS ASSET MANAGEMENT LLC11,428$858K0.01%-52413F-HRTimeline
Cetera Investment Advisers11,280$847K<0.01%+42413F-HRTimeline
Plancorp, LLC11,208$843K0.02%013F-HRTimeline
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…11,123$835K<0.01%-87513F-HRTimelineGroup
Capstone Capital Management Ltd21,447$832K0.84%new13F-HRTimeline
FIFTH THIRD BANCORPin group FIFTH THIRD BANK, NATIONAL AS…11,011$827K<0.01%+3,12313F-HRTimelineGroup
&PARTNERS10,909$819K<0.01%+1,18613F-HRTimeline
MONTANOVA CAPITAL, LLC10,800$811K0.02%013F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…10,445$784K0.22%+1,99113F-HRTimelineGroup
VIRGINIA RETIREMENT SYSTEMS ET Al10,300$773K0.01%-30013F-HRTimeline
Federation des caisses Desjardins du Qu…10,005$751K<0.01%-2,54813F-HRTimeline
Thrivent Financial for Lutheransin group Thrivent Financial for Luther…9,962$748K<0.01%013F-HRTimelineGroup
ASSETMARK, INCin group ASSETMARK, INC9,574$719K<0.01%+92413F-HRTimelineGroup
Vident Advisory, LLCin group Vident Advisory, LLC9,489$713K0.01%-74613F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…9,224$693K<0.01%-45013F-HRTimelineGroup
Swiss Life Asset Management Ltdin group Swiss Life Asset Management L…9,175$689K<0.01%+2,27213F-HRTimelineGroup
Aigen Investment Management, LP8,790$660K0.17%-7113F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.8,710$654K<0.01%-2,93613F-HRTimelineGroup
Savant Capital, LLCin group Savant Capital, LLC8,461$635K<0.01%+1,27213F-HRTimelineGroup
denkapparat Operations GmbH8,364$628K0.26%013F-HRTimeline
Utah Retirement Systems8,300$623K0.01%013F-HRTimeline
SECTORAL ASSET MANAGEMENT INC7,200$617K0.51%-1,16513F-HRTimeline
COMMERCE BANKin group COMMERCE BANK8,165$613K<0.01%+5413F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC7,829$588K<0.01%-3,97713F-HRTimeline
Stratos Wealth Partners, LTD.in group Stratos Wealth Partners, LTD.7,715$579K0.01%-2513F-HRTimelineGroup
O'SHAUGHNESSY ASSET MANAGEMENT, LLC7,687$577K<0.01%+65513F-HRTimeline
M&T Bank Corpin group M&T Bank Corp7,671$575K<0.01%-47913F-HR/ATimelineGroup
Cerity Partners LLCin group Cerity Partners LLC7,596$570K<0.01%-16,33113F-HRTimelineGroup
Fiduciary Trust Coin group Fiduciary Trust Co7,399$556K0.01%013F-HRTimelineGroup
Meeder Advisory Services, Inc.group of 2 filers holding7,391$555K-481Timeline
ProShare Advisors LLC7,390$555K<0.01%+23613F-HRTimeline
Maryland State Retirement & Pension Sys…7,380$554K0.01%-90413F-HRTimeline
Ground Swell Capital, LLC7,285$547K1.08%new13F-HRTimeline
Callan Family Office, LLC7,082$532K0.01%-2213F-HRTimeline
SILVERCREST ASSET MANAGEMENT GROUP LLC7,053$530K<0.01%-18913F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC7,019$527K<0.01%+3,68013F-HRTimelineGroup
PSP Research LLC6,800$511K0.36%013F-HRTimeline
Significant Wealth Partners LLC6,664$500K0.62%-10013F-HRTimeline
Wedmont Private Capital6,564$492K0.02%+1,02813F-HRTimeline
J. Safra Sarasin Holding AGin group J. Safra Sarasin Holding AG6,431$483K0.01%-10,97313F-HRTimelineGroup
MERCER GLOBAL ADVISORS INC /ADV6,296$473K<0.01%+74213F-HRTimeline
PRAXIS INVESTMENT MANAGEMENT INC6,232$468K0.03%-53813F-HRTimeline
REGIONS FINANCIAL CORPin group REGIONS FINANCIAL CORP6,122$460K<0.01%+3313F-HRTimelineGroup
Cypress Capital, LLC6,000$451K0.13%-4,00013F-HRTimeline
Frank, Rimerman Advisors LLC5,781$434K0.03%013F-HRTimeline
Tema ETFs LLC5,673$426K0.03%-2,88413F-HRTimeline
Robeco Institutional Asset Management B…in group Robeco Institutional Asset Ma…5,660$425K<0.01%new13F-HRTimelineGroup
COLDSTREAM CAPITAL MANAGEMENT INC5,653$424K0.01%-96613F-HRTimeline
Cynosure Group, LLC5,614$422K0.05%new13F-HRTimeline
Mesirow Financial Investment Management…5,460$410K0.01%new13F-HRTimeline
OneDigital Investment Advisors LLC5,390$405K<0.01%+38413F-HRTimeline
Granite Investment Partners, LLC5,345$401K0.02%+53913F-HRTimeline
Virtu Financial LLCin group Virtu Financial LLC5,342$401K0.02%new13F-HRTimelineGroup
Vontobel Holding Ltd.in group Vontobel Holding Ltd.5,240$393K<0.01%013F-HRTimelineGroup
Atria Investments, Inc5,227$392K<0.01%-42813F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\5,047$379K<0.01%-9413F-HRTimelineGroup
CIBC Asset Management Inc5,017$377K<0.01%013F-HRTimeline
CAPTRUST FINANCIAL ADVISORS5,000$375K<0.01%-29313F-HRTimeline
Moisand Fitzgerald Tamayo, LLC5,000$375K0.04%013F-HRTimeline
Lighthouse Investment Partners, LLCin group Lighthouse Investment Partner…4,970$373K0.01%-8,11213F-HRTimelineGroup
FARALLON CAPITAL MANAGEMENT, L.L.C.4,800$360K<0.01%013F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
NewEdge Advisors, LLC4,786$359K<0.01%-15213F-HR/ATimeline
North Dakota State Investment Board4,623$347K0.02%-85713F-HRTimeline
Vise Technologies, Inc.4,305$341K0.01%013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…4,466$335K0.01%+1,20313F-HRTimelineGroup
Checchi Capital Advisers, LLC4,429$333K0.02%+15713F-HRTimeline
CREDIT AGRICOLE S Ain group CREDIT AGRICOLE S A4,410$331K<0.01%013F-HRTimelineGroup
Kestra Advisory Services, LLCin group Kestra Advisory Services, LLC4,372$328K<0.01%-7913F-HRTimelineGroup
R Squared Ltd4,359$327K0.18%new13F-HRTimeline
Prospera Financial Services Inc4,341$326K0.01%-41813F-HRTimeline
Pinnacle Wealth Planning Services, Inc.4,213$316K0.03%+34913F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…4,155$312K<0.01%+1,42913F-HRTimelineGroup
Inspire Advisors, LLCin group Inspire Investing, LLC4,120$309K0.03%-73113F-HRTimelineGroup
WEALTH ENHANCEMENT ADVISORY SERVICES, L…4,125$309K<0.01%-4,13113F-HRTimeline
INTRUST BANK NA4,056$305K0.02%new13F-HRTimeline
Optas, LLC4,034$303K0.05%new13F-HRTimeline
Prime Capital Investment Advisors, LLC3,971$298K<0.01%-1013F-HRTimeline
CONGRESS ASSET MANAGEMENT CO3,946$296K<0.01%new13F-HRTimeline
Sanctuary Advisors, LLC3,918$294K<0.01%-58413F-HRTimeline
AXQ CAPITAL, LP3,846$289K0.04%new13F-HRTimeline
HighTower Advisors, LLC3,797$285K<0.01%-1,32513F-HRTimeline
MACKENZIE FINANCIAL CORP3,795$285K<0.01%-9613F-HRTimeline
ANB BANK3,769$283K0.11%+57613F-HRTimeline
CWM, LLCin group CWM, LLC3,717$279K<0.01%-1,33213F-HRTimelineGroup
Steward Partners Investment Advisory, L…3,639$273K<0.01%+2,57013F-HRTimeline
BERKSHIRE ASSET MANAGEMENT LLC/PA3,637$273K0.01%+713F-HRTimeline
GF FUND MANAGEMENT CO. LTD.3,637$273K<0.01%+45413F-HRTimeline
Marex Group Ltdin group Marex Group Ltd3,610$271K<0.01%+8613F-HRTimelineGroup
WESTFIELD CAPITAL MANAGEMENT CO LP3,502$263K<0.01%+34513F-HRTimeline
Everhart Financial Group, Inc.3,470$261K0.02%+513F-HRTimeline
Perigon Wealth Management, LLC3,430$258K<0.01%new13F-HRTimeline
Eurizon Capital SGR S.p.A.3,514$256K<0.01%+20013F-HRTimeline
MITCHELL & PAHL PRIVATE WEALTH, LLC3,261$245K0.1%-11813F-HRTimeline
NWAM LLC3,238$243K0.01%013F-HRTimeline
Crossmark Global Holdings, Inc.3,199$240K<0.01%+9713F-HRTimeline
MML INVESTORS SERVICES, LLC3,173$238K<0.01%-9113F-HRTimeline
GSA CAPITAL PARTNERS LLP3,172$238K0.01%new13F-HRTimeline
Raab & Moskowitz Asset Management LLC3,115$234K0.05%013F-HRTimeline
Campbell & CO Investment Adviser LLC3,101$233K0.01%+31713F-HRTimeline
QRG CAPITAL MANAGEMENT, INC.3,094$232K<0.01%new13F-HRTimeline
Venturi Wealth Management, LLC3,061$230K0.01%013F-HRTimeline
Larson Financial Group LLC3,031$228K0.01%+69113F-HRTimeline
Argent Trust Co3,018$227K0.01%013F-HRTimeline
EntryPoint Capital, LLC2,963$222K0.07%new13F-HRTimeline
HB Wealth Management, LLC2,926$220K<0.01%+413F-HRTimeline
NORDEN GROUP LLC2,889$217K0.02%-4613F-HRTimeline
Cambria Investment Management, L.P.2,885$217K0.01%-79913F-HRTimeline
B. Riley Wealth Advisors, Inc.2,945$214K0.01%-3013F-HRTimeline
Blueshift Asset Management, LLC2,777$209K0.06%-7,66613F-HRTimeline
AlphaCore Capital LLC2,762$207K<0.01%new13F-HRTimeline
Integrated Wealth Concepts LLC2,724$205K<0.01%new13F-HRTimeline
Montis Financial, LLC2,700$203K0.04%013F-HRTimeline
Mitsubishi UFJ Asset Management Co., Lt…in group Mitsubishi UFJ Trust & Bankin…2,693$202K<0.01%-5713F-HRTimelineGroup
New York Life Investment Management LLCin group New York Life Investment Mana…2,688$202K<0.01%new13F-HRTimelineGroup
Fideuram Asset Management (Ireland) dac2,213$182K0.02%new13F-HRTimeline
Ancora Advisors LLCin group Ancora Advisors LLC2,391$180K<0.01%+4913F-HRTimelineGroup
SIGNATUREFD, LLC2,078$156K<0.01%+3713F-HRTimeline
GROUP ONE TRADING LLC1,892$142K<0.01%-1,88613F-HRTimeline
Farther Finance Advisors, LLC1,883$141K<0.01%+68413F-HRTimeline
Parallel Advisors, LLC1,883$141K<0.01%+113F-HR/ATimeline
Advisors Asset Management, Inc.1,878$141K<0.01%-95713F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…1,794$135K<0.01%+65713F-HR/ATimelineGroup
GAMMA Investing LLC1,766$133K0.01%+3313F-HRTimeline
Versant Capital Management, Inc1,555$117K0.01%+5913F-HRTimeline
Sterling Capital Management LLC1,425$107K<0.01%-28813F-HRTimeline
Smartleaf Asset Management LLC1,416$103K<0.01%+2813F-HRTimeline
INTERNATIONAL ASSETS INVESTMENT MANAGEM…1,221$91.7K0.01%+413F-HRTimeline
STEPHENS INC /AR/in group Stephens Investment Managemen…26,761$91.4K<0.01%new13F-HRTimelineGroup
Sunbelt Securities, Inc.1,014$76.1K<0.01%013F-HRTimeline
IFP Advisors, Inc950$71.3K<0.01%-6413F-HRTimeline
MAI Capital Management940$70.6K<0.01%+4013F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC700$52.6K<0.01%013F-HRTimeline
HUNTINGTON NATIONAL BANKin group HUNTINGTON NATIONAL BANK681$51.1K<0.01%-1413F-HRTimelineGroup
Root Financial Partners, LLC681$51.1K<0.01%-65813F-HRTimeline
QUADRANT CAPITAL GROUP LLC616$46.3K<0.01%013F-HR/ATimeline
Advisory Services Network, LLC604$45.4K<0.01%new13F-HRTimeline
Archer Investment Corp600$45.1K0.01%013F-HRTimeline
AdvisorNet Financial, Inc573$43K<0.01%-4013F-HRTimeline
HARBOUR INVESTMENTS, INC.546$41K<0.01%+31813F-HRTimeline
Allworth Financial LP522$39.2K<0.01%-39813F-HRTimeline
Bayforest Capital Ltd413$31K0.03%-67813F-HRTimeline
MATHER GROUP, LLC.410$30.8K<0.01%new13F-HRTimeline
Cassaday & Co Wealth Management LLC400$30K<0.01%new13F-HRTimeline
Ascentis Wealth Management, LLCin group Ascentis Wealth Management, L…400$30K0.01%013F-HRTimelineGroup
Golden State Wealth Management, LLC376$28.2K<0.01%013F-HRTimeline
Destiny Wealth Partners, LLC375$28.2K<0.01%new13F-HRTimeline
Employees Retirement System of Texas378$28K<0.01%-97613F-HRTimeline
CoreCap Advisors, LLC370$27.8K<0.01%013F-HRTimeline
Hilton Head Capital Partners, LLC353$26.5K0.01%-24613F-HRTimeline
BROWN BROTHERS HARRIMAN & COin group BROWN BROTHERS HARRIMAN & CO341$25.6K<0.01%013F-HRTimelineGroup
WELLINGTON-ALTUS USA INC.317$25.1K0.01%-3413F-HRTimeline