Skip to content
Disclosery

HRTX HERON THERAPEUTICS INC

Follow

COM (common), issuer CIK 818033

168 managers (170 13F filers) reported a position in HRTX shares at 2025-12-31, 156,477,593 shares in all. 21 filers opened a position and 25 filers sold out during the quarter.

Managers
168
13F filers
170
New
21
Added
56
Reduced
44
Sold out
25
Shares held by filers
156,477,593

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Rubric Capital Management LP30,046,828$39.1M0.47%+946,10013F-HRTimeline
Clearline Capital LP12,235,239$15.9M1.2%+2,522,71213F-HRTimeline
ADAGE CAPITAL PARTNERS GP, L.L.C.in group ADAGE CAPITAL PARTNERS GP, L.…11,185,325$14.5M0.02%+946,10013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.10,218,236$13.3M<0.01%+230,77613F-HRTimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding9,835,280$12.8M+1,360,675Timeline
Velan Capital Investment Management LP8,753,290$11.4M6.62%013F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC7,169,908$9.32M0.01%+6,921,40513F-HRTimelineGroup
PALISADE CAPITAL MANAGEMENT, LP6,326,113$8.22M0.24%-1,001,33413F-HRTimeline
TANG CAPITAL MANAGEMENT LLCin group TANG CAPITAL MANAGEMENT LLC6,250,000$8.12M0.4%+2,800,00013F-HRTimelineGroup
Tejara Capital Ltd5,131,426$6.67M2.77%+541,71113F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC4,081,222$5.31M<0.01%+438,24013F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP3,778,043$4.91M<0.01%+126,54013F-HRTimelineGroup
JW Asset Management, LLC3,671,073$4.77M1.55%+378,44013F-HRTimeline
Congress Park Capital LLC3,067,475$3.99M1.19%+177,31813F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.3,004,640$3.91M<0.01%-83,85213F-HRTimelineGroup
Focus Partners Wealthin group Focus Partners Wealth148,470$3.57M<0.01%+129,85513F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND2,576,716$3.35M<0.01%013F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC2,095,045$2.72M<0.01%-613,41213F-HRTimelineGroup
UBS Group AGin group UBS Group AG2,091,669$2.72M<0.01%-842,41213F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC1,915,900$2.49M<0.01%-939,09913F-HRTimeline
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding1,519,080$1.97M+644,730Timeline
Pale Fire Capital SEin group Pale Fire Capital1,469,655$1.91M0.25%+998,46513F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co1,415,336$1.84M<0.01%+138,29513F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC1,367,891$1.78M<0.01%+1,147,58313F-HRTimelineGroup
Stonepine Capital Management, LLC1,237,802$1.61M1.27%+387,70213F-HRTimeline
Monaco Asset Management SAM1,233,022$1.6M0.48%+230,54613F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP1,091,411$1.42M<0.01%-66,16213F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC989,796$1.29M<0.01%-335,00613F-HR/ATimelineGroup
MORGAN STANLEYin group MORGAN STANLEY963,851$1.25M<0.01%-1,504,19013F-HR/ATimelineGroup
CM Management, LLC750,000$975K0.82%013F-HRTimeline
Orchard Capital Management, LLC680,432$885K0.77%+3,14213F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC677,947$881K<0.01%+462,84013F-HRTimelineGroup
Richmond Brothers, Inc.572,118$744K0.47%013F-HRTimeline
NEXPOINT ASSET MANAGEMENT, L.P.in group NEXPOINT ASSET MANAGEMENT, L.…475,750$618K0.04%013F-HRTimelineGroup
PANAGORA ASSET MANAGEMENT INC440,252$572K<0.01%new13F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp418,477$544K<0.01%+6,00313F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC376,300$489K<0.01%-1,560,38913F-HRTimelineGroup
Nuveen, LLCin group TIAA347,065$451K<0.01%013F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…340,246$442K<0.01%+11,27913F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.307,861$400K<0.01%+76,46613F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC303,209$394K<0.01%+23,85213F-HRTimelineGroup
Apeiron RIA LLC259,968$359K0.07%+37,09013F-HRTimeline
Palumbo Wealth Management LLC259,413$337K0.08%+42,90713F-HRTimeline
Cyndeo Wealth Partners, LLC248,087$323K0.02%013F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC242,000$315K0.01%-458,00013F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd240,197$312K0.01%+209,70013F-HRTimelineGroup
Quadrature Capital Ltdin group Quadrature Capital Ltd227,784$296K<0.01%new13F-HRTimelineGroup
LOS ANGELES CAPITAL MANAGEMENT LLC248,567$283K<0.01%+2,15413F-HRTimeline
RHUMBLINE ADVISERS203,319$264K<0.01%-21,33413F-HRTimeline
ALLIANCEBERNSTEIN L.P.198,550$258K<0.01%013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN179,620$234K<0.01%+56,48813F-HRTimelineGroup
Quinn Opportunity Partners LLC175,344$228K0.01%013F-HRTimeline
GROUP ONE TRADING LLC145,167$189K0.01%new13F-HRTimeline
Capital Planning Advisors, LLC144,095$187K0.03%013F-HRTimeline
GSA CAPITAL PARTNERS LLP135,089$176K0.02%+34,90813F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/134,445$175K<0.01%-597,62813F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC120,199$156K<0.01%+8,52713F-HRTimelineGroup
SIMPLEX TRADING, LLC114,604$149K<0.01%+87,73413F-HRTimeline
Biltmore Family Office, LLC100,000$130K0.02%013F-HRTimeline
Integrated Wealth Concepts LLC95,174$124K<0.01%-2,42113F-HRTimeline
Connor, Clark & Lunn Investment Managem…94,009$122K<0.01%+10,31413F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\93,081$121K<0.01%+7,92313F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…87,754$114K<0.01%-4,67213F-HRTimelineGroup
SEARLE & CO.86,250$112K0.03%013F-HRTimeline
FMR LLCin group FMR LLC84,197$109K<0.01%+36,80313F-HRTimelineGroup
GLENMEDE TRUST CO NAin group GLENMEDE TRUST CO NA82,189$107K<0.01%13F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/76,638$100K<0.01%013F-HRTimeline
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…71,369$92.8K<0.01%-49113F-HRTimelineGroup
Redwood Family Wealth LLC64,500$83.8K0.08%13F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO62,396$81.1K<0.01%-1,230,04813F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC59,426$77.2K<0.01%-62013F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC59,369$77.2K<0.01%-13,99613F-HRTimeline
State of Wyoming58,624$76.2K0.01%new13F-HRTimeline
Cornerstone Select Advisors, LLC58,070$75.5K0.05%-1,00013F-HRTimeline
LPL Financial LLC55,889$72.7K<0.01%+5,25613F-HRTimeline
Headlands Technologies LLC51,287$66.7K0.01%+31,43113F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …48,659$63.3K<0.01%-3,30913F-HRTimelineGroup
Atom Investors LP48,178$62.6K<0.01%new13F-HRTimeline
Abel Hall, LLC46,176$60K0.01%new13F-HRTimeline
CAPTRUST FINANCIAL ADVISORS41,590$54.1K<0.01%-7,36613F-HRTimeline
Prospera Financial Services Inc40,565$52.7K<0.01%-11,10013F-HRTimeline
Police & Firemen's Retirement System of…38,352$49.9K<0.01%013F-HRTimeline
Caitong International Asset Management …35,106$45.6K0.01%+27,04013F-HR/ATimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…35,036$45.5K<0.01%new13F-HRTimelineGroup
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC33,381$43.9K<0.01%-5313F-HR/ATimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS32,870$42.7K<0.01%-345,71813F-HRTimelineGroup
Concurrent Investment Advisors, LLCin group Concurrent Investment Advisor…31,923$41.5K<0.01%new13F-HRTimelineGroup
King Wealth Management Group30,799$40K<0.01%+1,00013F-HRTimeline
Anfield Capital Management, LLCin group Anfield Capital Management, L…30,000$39K0.01%013F-HRTimelineGroup
CoreCap Advisors, LLC28,409$36.9K<0.01%013F-HRTimeline
ProShare Advisors LLC28,075$36.5K<0.01%+1,91613F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP27,955$36.3K<0.01%+3,86713F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC27,653$35.9K<0.01%013F-HRTimelineGroup
Valeo Financial Advisors, LLC26,697$34.7K<0.01%013F-HRTimeline
Cambridge Investment Research Advisors,…26,422$34K<0.01%-20013F-HRTimeline
ACT Advisors, LLC.25,808$33.5K0.01%+22713F-HRTimeline
Parkway Wealth Management Group, LLC25,000$32.5K<0.01%13F-HRTimeline
SG Americas Securities, LLC24,377$32K<0.01%+6,85813F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC20,914$27.2K<0.01%+2913F-HRTimeline
Argent Advisors, Inc.20,000$26K0.01%013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…19,393$25.2K<0.01%+7,88013F-HRTimelineGroup
Mariner, LLCin group Mariner, LLC18,999$24.7K<0.01%-16,90013F-HRTimelineGroup
Advisory Services Network, LLC18,874$24.5K<0.01%+18,11413F-HRTimeline
StoneX Group Inc.in group StoneX Group Inc.18,809$24.5K<0.01%new13F-HRTimelineGroup
NICOLET ADVISORY SERVICES, LLCin group NICOLET BANKSHARES INC16,000$23.8K<0.01%013F-HRTimelineGroup
Capital Investment Counsel, Inc18,325$23.8K<0.01%new13F-HRTimeline
Cerity Partners LLCin group Cerity Partners LLC17,063$22.2K<0.01%-34,64913F-HRTimelineGroup
IEQ CAPITAL, LLC16,988$22.1K<0.01%-62,03713F-HRTimeline
HighTower Advisors, LLC16,796$21.8K<0.01%-4,00013F-HRTimeline
J.W. COLE ADVISORS, INC.16,000$20.8K<0.01%013F-HRTimeline
Pekin Hardy Strauss, Inc.15,992$20.8K<0.01%new13F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…15,618$20.3K<0.01%013F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc14,237$18.5K<0.01%013F-HRTimelineGroup
Cetera Investment Advisers13,997$18.2K<0.01%013F-HRTimeline
Cresset Asset Management, LLC13,390$17.4K<0.01%new13F-HRTimeline
MERCER GLOBAL ADVISORS INC /ADV13,380$17.4K<0.01%-13,32913F-HRTimeline
Aigen Investment Management, LP12,717$16.5K<0.01%new13F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO12,685$16.5K<0.01%013F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…12,671$16.5K<0.01%-4,54713F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA11,793$16K<0.01%+5,83213F-HRTimelineGroup
TWO SIGMA SECURITIES, LLC12,136$15.8K<0.01%new13F-HRTimeline
B. Riley Wealth Advisors, Inc.12,117$15.8K<0.01%013F-HRTimeline
XPONANCE LLC11,893$15.5K<0.01%013F-HRTimeline
DLK Investment Management, LLC11,690$15.2K0.01%-10,50013F-HRTimeline
INGALLS & SNYDER LLC11,415$15K<0.01%013F-HRTimeline
CWM, LLCin group CWM, LLC10,628$14K<0.01%-34,38713F-HRTimelineGroup
Venturi Wealth Management, LLC10,500$13.7K<0.01%013F-HRTimeline
Red Door Wealth Management, LLC10,400$13.5K<0.01%new13F-HRTimeline
HB Wealth Management, LLC10,301$13.4K<0.01%-1,16913F-HRTimeline
CIBC WORLD MARKETS CORPin group CIBC Bancorp USA Inc.10,165$13.2K<0.01%13F-HRTimelineGroup
XML Financial, LLC10,000$13K<0.01%013F-HRTimeline
Lido Advisors, LLCin group Lido Advisors, LLC10,072$12.7K<0.01%013F-HRTimelineGroup
HBK Sorce Advisory LLC10,000$12.6K<0.01%013F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…9,458$12.3K<0.01%+94313F-HRTimeline
Allworth Financial LP9,329$12.1K<0.01%+7,77513F-HRTimeline
Sterling Capital Management LLC7,976$10.4K<0.01%-1,43813F-HRTimeline
JTC Employer Solutions Trustee Ltd6,500$8K<0.01%013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.4,968$6.46K<0.01%+1,07713F-HRTimelineGroup
COMERICA BANK4,951$6.44K<0.01%-6813F-HRTimeline
AMALGAMATED BANK4,827$6K<0.01%+78013F-HRTimeline
Global Retirement Partners, LLC4,018$5.22K<0.01%013F-HRTimeline
CITIGROUP INCin group CITIGROUP INC3,478$4.52K<0.01%-2,473,05113F-HRTimelineGroup
Clearstead Advisors, LLC3,200$4.16K<0.01%-1,56113F-HRTimeline
Essential Partners LLC2,200$2.86K<0.01%-6,75113F-HRTimeline
N.E.W. Advisory Services LLC1,619$2.1K<0.01%013F-HRTimeline
BESSEMER GROUP INCin group BESSEMER GROUP INC1,300$2K<0.01%013F-HRTimelineGroup
Optiver Holding B.V.in group Optiver Holding B.V.1,088$1.41K<0.01%-79413F-HRTimelineGroup
HARBOUR INVESTMENTS, INC.1,000$1.3K<0.01%new13F-HRTimeline
Winch Advisory Services, LLC1,000$1.3K<0.01%013F-HRTimeline
Steward Partners Investment Advisory, L…1,000$1.3K<0.01%013F-HRTimeline
GAMMA Investing LLC889$1.16K<0.01%new13F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…641$833<0.01%-1,10413F-HRTimelineGroup
New England Capital Financial Advisors …475$618<0.01%013F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…415$539<0.01%+35413F-HR/ATimelineGroup
SJS Investment Consulting Inc.400$520<0.01%013F-HRTimeline
IFP Advisors, Inc361$469<0.01%-15513F-HRTimeline
Lodestone Wealth Management LLC250$325<0.01%new13F-HRTimeline
Parallel Advisors, LLC200$260<0.01%013F-HRTimeline
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…188$244<0.01%new13F-HR/ATimelineGroup
Pinnacle Wealth Planning Services, Inc.178$231<0.01%new13F-HRTimeline
Arax Advisory Partners129$168<0.01%-33,24513F-HRTimeline
AdvisorNet Financial, Inc110$143<0.01%013F-HRTimeline
EVERMAY WEALTH MANAGEMENT LLC100$130<0.01%013F-HRTimeline
HighMark Wealth Management LLC100$130<0.01%013F-HRTimeline
Fortitude Family Office, LLC79$103<0.01%-1013F-HRTimeline
ROTHSCHILD INVESTMENT LLC55$72<0.01%+2313F-HRTimeline
Farther Finance Advisors, LLC52$68<0.01%new13F-HRTimeline
SBI Securities Co., Ltd.1$1<0.01%013F-HRTimeline