Cormorant Asset Management, LP More: the full row for Cormorant Asset Management, LP 2,375,000 $12.6M 0.95% 0 13F-HR Timeline ORBIMED ADVISORS LLC in group ORBIMED ADVISORS LLC More: the full row for ORBIMED ADVISORS LLC 1,172,287 $6.22M 0.15% 0 13F-HR Timeline Group Octagon Capital Advisors LP More: the full row for Octagon Capital Advisors LP 1,115,000 $5.92M 1.17% 0 13F-HR/A Timeline BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 846,062 $4.49M <0.01% -27,312 13F-HR Timeline Group VANGUARD GROUP INC in group VANGUARD GROUP INC More: the full row for VANGUARD GROUP INC 672,057 $3.57M <0.01% +12,855 13F-HR Timeline Group Prosight Management, LP More: the full row for Prosight Management, LP 575,136 $3.05M 1% +305,136 13F-HR Timeline RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 345,200 $1.83M <0.01% +206,100 13F-HR Timeline Exome Asset Management LLC More: the full row for Exome Asset Management LLC 289,690 $1.54M 1.38% new 13F-HR/A Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 271,514 $1.44M <0.01% +7,982 13F-HR Timeline Group ARMISTICE CAPITAL, LLC More: the full row for ARMISTICE CAPITAL, LLC 250,000 $1.33M 0.04% +14,000 13F-HR Timeline STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 223,470 $1.19M <0.01% -5,130 13F-HR Timeline Group COMERICA BANK More: the full row for COMERICA BANK 200,001 $1.06M <0.01% +200,000 13F-HR Timeline ACADIAN ASSET MANAGEMENT LLC in group ACADIAN ASSET MANAGEMENT LLC More: the full row for ACADIAN ASSET MANAGEMENT LLC 190,093 $1.01M <0.01% new 13F-HR Timeline Group TWO SIGMA INVESTMENTS, LP group of 2 filers holding More: the full row for TWO SIGMA INVESTMENTS, LP 157,304 $835K +12,102 Timeline MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. in group Mirae Asset Global Investment… More: the full row for MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 129,043 $685K <0.01% -33,919 13F-HR Timeline Group TANG CAPITAL MANAGEMENT LLC in group TANG CAPITAL MANAGEMENT LLC More: the full row for TANG CAPITAL MANAGEMENT LLC 127,520 $677K 0.04% -115,133 13F-HR Timeline Group AQR CAPITAL MANAGEMENT LLC in group AQR CAPITAL MANAGEMENT LLC More: the full row for AQR CAPITAL MANAGEMENT LLC 107,983 $573K <0.01% new 13F-HR Timeline Group MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 101,607 $540K <0.01% -285,046 13F-HR Timeline Group NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 99,883 $530K <0.01% -3,381 13F-HR Timeline Group Atle Fund Management AB More: the full row for Atle Fund Management AB 98,304 $522K 0.23% 0 13F-HR Timeline CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 92,991 $494K <0.01% new 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 90,844 $482K <0.01% +1,467 13F-HR Timeline Group CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 88,525 $470K <0.01% -9,357 13F-HR/A Timeline Group PRELUDE CAPITAL MANAGEMENT, LLC More: the full row for PRELUDE CAPITAL MANAGEMENT, LLC 80,347 $427K 0.04% new 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 76,611 $407K <0.01% +14,980 13F-HR Timeline Group HighVista Strategies LLC More: the full row for HighVista Strategies LLC 75,292 $400K 0.15% 0 13F-HR Timeline Velan Capital Investment Management LP More: the full row for Velan Capital Investment Management LP 59,000 $313K 0.32% +2,300 13F-HR Timeline GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 57,936 $308K <0.01% +762 13F-HR/A Timeline Group AlphaQuest LLC More: the full row for AlphaQuest LLC 56,390 $299K 0.03% new 13F-HR Timeline Nuveen, LLC in group TIAA More: the full row for Nuveen, LLC 45,689 $243K <0.01% 13F-HR Timeline Group Stonepine Capital Management, LLC More: the full row for Stonepine Capital Management, LLC 35,000 $186K 0.18% new 13F-HR Timeline SCHRODER INVESTMENT MANAGEMENT GROUP More: the full row for SCHRODER INVESTMENT MANAGEMENT GROUP 31,295 $173K <0.01% 0 13F-HR Timeline Aberdeen Group plc in group Aberdeen Group plc More: the full row for Aberdeen Group plc 26,894 $143K <0.01% 0 13F-HR Timeline Group Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 23,206 $123K <0.01% -1 13F-HR Timeline Group Verition Fund Management LLC More: the full row for Verition Fund Management LLC 22,485 $119K <0.01% new 13F-HR Timeline JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 21,861 $116K <0.01% -12,271 13F-HR/A Timeline Group SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 18,218 $96.7K <0.01% -11,596 13F-HR Timeline Group SEI INVESTMENTS CO in group SEI INVESTMENTS CO More: the full row for SEI INVESTMENTS CO 17,589 $93.4K <0.01% new 13F-HR/A Timeline Group BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 16,579 $88K <0.01% -14,896 13F-HR Timeline Group WEXFORD CAPITAL LP More: the full row for WEXFORD CAPITAL LP 15,400 $81.8K 0.02% -29,621 13F-HR Timeline RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 15,139 $80.4K <0.01% +25 13F-HR/A Timeline OCCUDO QUANTITATIVE STRATEGIES LP More: the full row for OCCUDO QUANTITATIVE STRATEGIES LP 13,073 $72.2K 0.01% new 13F-HR Timeline BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 12,470 $66.2K <0.01% -5,686 13F-HR/A Timeline Group Mariner, LLC in group Mariner, LLC More: the full row for Mariner, LLC 12,290 $65.3K <0.01% new 13F-HR Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 8,298 $44.1K <0.01% -912 13F-HR Timeline Group DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 7,045 $37.4K <0.01% -1,161 13F-HR Timeline Group Avanza Fonder AB More: the full row for Avanza Fonder AB 7,150 $37.2K <0.01% 0 13F-HR Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 6,648 $35.3K <0.01% +204 13F-HR Timeline Group ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 6,419 $34K <0.01% -25,221 13F-HR/A Timeline Group SIMPLEX TRADING, LLC More: the full row for SIMPLEX TRADING, LLC 5,873 $31K <0.01% +4,974 13F-HR Timeline Corebridge Financial, Inc. in group Corebridge Financial, Inc. More: the full row for Corebridge Financial, Inc. 5,772 $30.6K <0.01% -20 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 5,725 $30.4K <0.01% +448 13F-HR Timeline Group NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 4,100 $21.2K <0.01% 0 13F-HR/A Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 3,652 $19.4K <0.01% -23,731 13F-HR Timeline Group FMR LLC in group FMR LLC More: the full row for FMR LLC 3,371 $17.9K <0.01% +3,219 13F-HR Timeline Group Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 2,831 $15K <0.01% -1,895 13F-HR Timeline Group CWM, LLC in group CWM, LLC More: the full row for CWM, LLC 2,752 $15K <0.01% +2,698 13F-HR Timeline Group Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 2,043 $10.8K <0.01% 0 13F-HR Timeline JTC Employer Solutions Trustee Ltd More: the full row for JTC Employer Solutions Trustee Ltd 1,106 $6K <0.01% 0 13F-HR Timeline Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 1,103 $5.86K <0.01% 0 13F-HR Timeline Group Ameritas Investment Partners, Inc. in group Ameritas Investment Partners,… More: the full row for Ameritas Investment Partners, Inc. 996 $5.29K <0.01% 0 13F-HR Timeline Group CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 867 $4.6K <0.01% 0 13F-HR Timeline Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 511 $2.71K <0.01% +438 13F-HR Timeline GAMMA Investing LLC More: the full row for GAMMA Investing LLC 456 $2.42K <0.01% +250 13F-HR/A Timeline AMALGAMATED BANK More: the full row for AMALGAMATED BANK 352 $2K <0.01% 0 13F-HR Timeline MAI Capital Management More: the full row for MAI Capital Management 185 $983 <0.01% 0 13F-HR Timeline MassMutual Private Wealth & Trust, FSB More: the full row for MassMutual Private Wealth & Trust, FSB 148 $786 <0.01% new 13F-HR Timeline EverSource Wealth Advisors, LLC in group EverSource Wealth Advisors, L… More: the full row for EverSource Wealth Advisors, LLC 100 $531 <0.01% +99 13F-HR Timeline Group ORG Partners LLC More: the full row for ORG Partners LLC 100 $503 <0.01% new 13F-HR Timeline OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 89 $472 <0.01% +76 13F-HR Timeline Group Sterling Capital Management LLC More: the full row for Sterling Capital Management LLC 86 $457 <0.01% -58 13F-HR Timeline Golden State Wealth Management, LLC More: the full row for Golden State Wealth Management, LLC 73 $388 <0.01% 0 13F-HR/A Timeline JONES FINANCIAL COMPANIES LLLP in group JONES FINANCIAL COMPANIES LLLP More: the full row for JONES FINANCIAL COMPANIES LLLP 63 $348 <0.01% -34 13F-HR/A Timeline Group FEDERATED HERMES, INC. in group FEDERATED HERMES, INC. More: the full row for FEDERATED HERMES, INC. 64 $340 <0.01% new 13F-HR Timeline Group SBI Securities Co., Ltd. More: the full row for SBI Securities Co., Ltd. 62 $329 <0.01% -41 13F-HR Timeline CURIO WEALTH, LLC More: the full row for CURIO WEALTH, LLC 1 $271 <0.01% -22 13F-HR Timeline HighMark Wealth Management LLC More: the full row for HighMark Wealth Management LLC 41 $218 <0.01% 0 13F-HR Timeline Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 29 $154 <0.01% +9 13F-HR Timeline Group VISION FINANCIAL MARKETS LLC More: the full row for VISION FINANCIAL MARKETS LLC 14 $75 <0.01% 0 13F-HR Timeline Fortis Group Advisors, LLC More: the full row for Fortis Group Advisors, LLC 14 $74 <0.01% 0 13F-HR Timeline NewEdge Advisors, LLC More: the full row for NewEdge Advisors, LLC 9 $47 <0.01% +1 13F-HR Timeline EASTERN BANK More: the full row for EASTERN BANK 6 $32 <0.01% new 13F-HR Timeline NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO in group NORTHWESTERN MUTUAL INVESTMEN… More: the full row for NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO 2 $11 <0.01% new 13F-HR Timeline Group BFSG, LLC More: the full row for BFSG, LLC 1 $6 <0.01% 0 13F-HR Timeline CIBC Private Wealth Group LLC in group CIBC Bancorp USA Inc. More: the full row for CIBC Private Wealth Group LLC 1 $5 <0.01% 0 13F-HR Timeline Group CONCOURSE FINANCIAL GROUP SECURITIES, I… More: the full row for CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0 $0 0 13F-HR Timeline Value filed as zero, left out of ratios. Amount filed as zero, left out of ratios.