Cormorant Asset Management, LP More: the full row for Cormorant Asset Management, LP 2,375,000 $16.4M 1.22% 0 13F-HR Timeline ORBIMED ADVISORS LLC in group ORBIMED ADVISORS LLC More: the full row for ORBIMED ADVISORS LLC 1,172,287 $8.09M 0.2% 0 13F-HR Timeline Group Octagon Capital Advisors LP More: the full row for Octagon Capital Advisors LP 1,115,000 $7.69M 1.69% 0 13F-HR Timeline VANGUARD GROUP INC in group VANGUARD GROUP INC More: the full row for VANGUARD GROUP INC 599,495 $4.14M <0.01% -72,562 13F-HR Timeline Group Prosight Management, LP More: the full row for Prosight Management, LP 579,893 $4M 0.98% +4,757 13F-HR Timeline BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 352,409 $2.43M <0.01% -493,653 13F-HR Timeline Group Exome Asset Management LLC More: the full row for Exome Asset Management LLC 277,317 $1.91M 1.58% -12,373 13F-HR/A Timeline COMERICA BANK More: the full row for COMERICA BANK 200,001 $1.38M 0.01% 0 13F-HR Timeline ARMISTICE CAPITAL, LLC More: the full row for ARMISTICE CAPITAL, LLC 192,000 $1.32M 0.05% -58,000 13F-HR Timeline Atle Fund Management AB More: the full row for Atle Fund Management AB 175,582 $1.21M 0.52% +77,278 13F-HR Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 159,162 $1.1M <0.01% +57,555 13F-HR Timeline Group MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 158,999 $1.1M <0.01% +82,388 13F-HR Timeline Group RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 153,539 $1.06M <0.01% -191,661 13F-HR Timeline ACADIAN ASSET MANAGEMENT LLC in group ACADIAN ASSET MANAGEMENT LLC More: the full row for ACADIAN ASSET MANAGEMENT LLC 152,271 $1.05M <0.01% -37,822 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 134,091 $926K <0.01% -137,423 13F-HR Timeline Group TANG CAPITAL MANAGEMENT LLC in group TANG CAPITAL MANAGEMENT LLC More: the full row for TANG CAPITAL MANAGEMENT LLC 127,520 $880K 0.04% 0 13F-HR Timeline Group MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. in group Mirae Asset Global Investment… More: the full row for MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 119,056 $821K <0.01% -9,987 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 91,843 $634K <0.01% +999 13F-HR Timeline Group PRELUDE CAPITAL MANAGEMENT, LLC More: the full row for PRELUDE CAPITAL MANAGEMENT, LLC 80,347 $554K 0.05% 0 13F-HR Timeline HighVista Strategies LLC More: the full row for HighVista Strategies LLC 75,292 $520K 0.19% 0 13F-HR Timeline Aberdeen Group plc in group Aberdeen Group plc More: the full row for Aberdeen Group plc 72,226 $498K <0.01% +45,332 13F-HR Timeline Group BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 71,893 $496K <0.01% +55,314 13F-HR Timeline Group CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 68,148 $470K <0.01% -20,377 13F-HR Timeline Group TWO SIGMA INVESTMENTS, LP group of 2 filers holding More: the full row for TWO SIGMA INVESTMENTS, LP 61,841 $427K -95,463 Timeline Velan Capital Investment Management LP More: the full row for Velan Capital Investment Management LP 59,000 $407K 0.41% 0 13F-HR Timeline STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 55,092 $380K <0.01% -168,378 13F-HR Timeline Group GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 43,674 $301K <0.01% -14,262 13F-HR Timeline Group SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 43,332 $299K <0.01% +25,114 13F-HR Timeline Group NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 31,651 $218K <0.01% -68,232 13F-HR Timeline Group AlphaQuest LLC More: the full row for AlphaQuest LLC 31,536 $218K 0.02% -24,854 13F-HR Timeline AQR CAPITAL MANAGEMENT LLC in group AQR CAPITAL MANAGEMENT LLC More: the full row for AQR CAPITAL MANAGEMENT LLC 28,407 $196K <0.01% -79,576 13F-HR Timeline Group Y-Intercept (Hong Kong) Ltd More: the full row for Y-Intercept (Hong Kong) Ltd 20,437 $141K <0.01% new 13F-HR Timeline Baker Avenue Asset Management, LP More: the full row for Baker Avenue Asset Management, LP 20,000 $138K <0.01% new 13F-HR Timeline MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 19,871 $137K <0.01% new 13F-HR Timeline Group JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 18,878 $130K <0.01% -2,983 13F-HR Timeline Group Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 17,898 $123K <0.01% new 13F-HR/A Timeline Group Aster Capital Management (DIFC) Ltd More: the full row for Aster Capital Management (DIFC) Ltd 16,509 $114K 0.03% new 13F-HR Timeline Mariner, LLC in group Mariner, LLC More: the full row for Mariner, LLC 15,551 $107K <0.01% +3,261 13F-HR Timeline Group Corton Capital Inc. More: the full row for Corton Capital Inc. 12,516 $86.4K 0.1% new 13F-HR Timeline Jain Global LLC More: the full row for Jain Global LLC 12,369 $85.3K <0.01% new 13F-HR Timeline HRT FINANCIAL LP More: the full row for HRT FINANCIAL LP 11,548 $79K <0.01% new 13F-HR Timeline ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 9,135 $62K <0.01% +2,716 13F-HR/A Timeline Group Avanza Fonder AB More: the full row for Avanza Fonder AB 7,150 $49.3K <0.01% 0 13F-HR Timeline Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 4,833 $33.3K <0.01% +2,002 13F-HR Timeline Group SIMPLEX TRADING, LLC More: the full row for SIMPLEX TRADING, LLC 2,819 $19K <0.01% -3,054 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 2,256 $15.6K <0.01% -1,396 13F-HR Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 1,657 $11.4K <0.01% -6,641 13F-HR Timeline Group CWM, LLC in group CWM, LLC More: the full row for CWM, LLC 1,599 $11K <0.01% -1,153 13F-HR Timeline Group FMR LLC in group FMR LLC More: the full row for FMR LLC 1,455 $10K <0.01% -1,916 13F-HR Timeline Group JTC Employer Solutions Trustee Ltd More: the full row for JTC Employer Solutions Trustee Ltd 1,106 $8K <0.01% 0 13F-HR Timeline FEDERATED HERMES, INC. in group FEDERATED HERMES, INC. More: the full row for FEDERATED HERMES, INC. 1,130 $7.8K <0.01% +1,066 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 983 $6.78K <0.01% -4,742 13F-HR Timeline Group Versant Capital Management, Inc More: the full row for Versant Capital Management, Inc 601 $4.15K <0.01% new 13F-HR Timeline BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 591 $4.08K <0.01% -11,879 13F-HR/A Timeline Group RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 482 $3.33K <0.01% -14,657 13F-HR Timeline RAYMOND JAMES FINANCIAL INC in group RAYMOND JAMES FINANCIAL INC More: the full row for RAYMOND JAMES FINANCIAL INC 434 $2.99K <0.01% new 13F-HR Timeline Group GAMMA Investing LLC More: the full row for GAMMA Investing LLC 336 $2.32K <0.01% -120 13F-HR Timeline EverSource Wealth Advisors, LLC in group EverSource Wealth Advisors, L… More: the full row for EverSource Wealth Advisors, LLC 330 $2.28K <0.01% +230 13F-HR Timeline Group NISA INVESTMENT ADVISORS, LLC More: the full row for NISA INVESTMENT ADVISORS, LLC 287 $1.98K <0.01% new 13F-HR Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 251 $1.73K <0.01% -6,397 13F-HR Timeline Group JONES FINANCIAL COMPANIES LLLP in group JONES FINANCIAL COMPANIES LLLP More: the full row for JONES FINANCIAL COMPANIES LLLP 213 $1.58K <0.01% +150 13F-HR Timeline Group MAI Capital Management More: the full row for MAI Capital Management 185 $1.28K <0.01% 0 13F-HR Timeline Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 126 $869 <0.01% +97 13F-HR Timeline Group OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 125 $800 <0.01% +36 13F-HR/A Timeline Group Essential Partners LLC More: the full row for Essential Partners LLC 109 $752 <0.01% 13F-HR Timeline ORG Partners LLC More: the full row for ORG Partners LLC 100 $716 <0.01% 0 13F-HR Timeline Golden State Wealth Management, LLC More: the full row for Golden State Wealth Management, LLC 73 $504 <0.01% 0 13F-HR Timeline SBI Securities Co., Ltd. More: the full row for SBI Securities Co., Ltd. 54 $373 <0.01% -8 13F-HR Timeline Brooklyn Investment Group More: the full row for Brooklyn Investment Group 41 $283 <0.01% new 13F-HR/A Timeline HighMark Wealth Management LLC More: the full row for HighMark Wealth Management LLC 41 $283 <0.01% 0 13F-HR Timeline IFP Advisors, Inc More: the full row for IFP Advisors, Inc 15 $213 <0.01% new 13F-HR Timeline CURIO WEALTH, LLC More: the full row for CURIO WEALTH, LLC 23 $159 <0.01% +22 13F-HR Timeline VISION FINANCIAL MARKETS LLC More: the full row for VISION FINANCIAL MARKETS LLC 14 $97 <0.01% 0 13F-HR Timeline Fortis Group Advisors, LLC More: the full row for Fortis Group Advisors, LLC 14 $97 <0.01% 0 13F-HR Timeline NewEdge Advisors, LLC More: the full row for NewEdge Advisors, LLC 8 $55 <0.01% -1 13F-HR Timeline EASTERN BANK More: the full row for EASTERN BANK 6 $41 <0.01% 0 13F-HR Timeline Scarborough Advisors, LLC More: the full row for Scarborough Advisors, LLC 6 $41 <0.01% new 13F-HR Timeline CIBC Private Wealth Group LLC in group CIBC Bancorp USA Inc. More: the full row for CIBC Private Wealth Group LLC 1 $7 <0.01% 0 13F-HR Timeline Group BFSG, LLC More: the full row for BFSG, LLC 1 $7 <0.01% 0 13F-HR Timeline CONCOURSE FINANCIAL GROUP SECURITIES, I… More: the full row for CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0 $0 0 13F-HR Timeline Value filed as zero, left out of ratios. Amount filed as zero, left out of ratios.