Cormorant Asset Management, LP More: the full row for Cormorant Asset Management, LP 17,878,594 $207M 14.29% new 13F-HR Timeline DEERFIELD MANAGEMENT COMPANY, L.P. in group DEERFIELD MANAGEMENT COMPANY,… More: the full row for DEERFIELD MANAGEMENT COMPANY, L.P. 4,885,446 $56.6M 0.87% new 13F-HR Timeline Group Omega Fund Management, LLC More: the full row for Omega Fund Management, LLC 3,289,661 $38.1M 17.13% new 13F-HR Timeline WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 2,961,263 $34.3M 0.01% new 13F-HR Timeline Group EcoR1 Capital, LLC More: the full row for EcoR1 Capital, LLC 2,823,126 $32.7M 1.57% new 13F-HR Timeline Alphabet Inc. in group Alphabet Inc. More: the full row for Alphabet Inc. 2,823,126 $32.7M 1.36% new 13F-HR Timeline Group ENAVATE SCIENCES GP, LLC More: the full row for ENAVATE SCIENCES GP, LLC 2,626,946 $30.4M 9.29% new 13F-HR Timeline CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 2,538,141 $29.4M 0.02% new 13F-HR Timeline Group BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 2,048,552 $23.7M <0.01% new 13F-HR Timeline Group NOVO HOLDINGS A/S More: the full row for NOVO HOLDINGS A/S 1,961,317 $22.7M 1.46% new 13F-HR Timeline Paradigm Biocapital Advisors LP in group Paradigm Biocapital Advisors … More: the full row for Paradigm Biocapital Advisors LP 1,866,141 $21.6M 0.64% new 13F-HR Timeline Group ADAGE CAPITAL PARTNERS GP, L.L.C. in group ADAGE CAPITAL PARTNERS GP, L.… More: the full row for ADAGE CAPITAL PARTNERS GP, L.L.C. 1,487,621 $17.2M 0.03% new 13F-HR Timeline Group EVENTIDE ASSET MANAGEMENT, LLC More: the full row for EVENTIDE ASSET MANAGEMENT, LLC 1,082,362 $12.4M 0.2% new 13F-HR Timeline Laurion Capital Management LP More: the full row for Laurion Capital Management LP 1,045,800 $12.1M 1.65% new 13F-HR Timeline Octagon Capital Advisors LP More: the full row for Octagon Capital Advisors LP 1,043,110 $12.1M 1.89% new 13F-HR Timeline PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 885,042 $10.2M <0.01% new 13F-HR Timeline VANGUARD GROUP INC in group VANGUARD GROUP INC More: the full row for VANGUARD GROUP INC 647,599 $7.5M <0.01% new 13F-HR Timeline Group Aisling Capital Management LP More: the full row for Aisling Capital Management LP 564,625 $6.54M 1.43% new 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 541,602 $6.27M <0.01% new 13F-HR Timeline Group ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 501,228 $5.8M 0.57% new 13F-HR Timeline Group SILVERARC CAPITAL MANAGEMENT, LLC in group SILVERARC CAPITAL MANAGEMENT,… More: the full row for SILVERARC CAPITAL MANAGEMENT, LLC 457,414 $5.3M 0.77% new 13F-HR Timeline Group ARMISTICE CAPITAL, LLC More: the full row for ARMISTICE CAPITAL, LLC 412,000 $4.77M 0.15% new 13F-HR Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 369,563 $4.06M <0.01% new 13F-HR Timeline Group Casdin Capital, LLC More: the full row for Casdin Capital, LLC 282,312 $3.27M 0.27% new 13F-HR Timeline CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 279,350 $3.23M <0.01% new 13F-HR Timeline Group Ikarian Capital, LLC in group Ikarian Capital, LLC More: the full row for Ikarian Capital, LLC 245,231 $2.84M 0.57% new 13F-HR Timeline Group STEMPOINT CAPITAL LP More: the full row for STEMPOINT CAPITAL LP 186,614 $2.16M 0.44% new 13F-HR Timeline STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 176,695 $2.05M <0.01% new 13F-HR Timeline Group FMR LLC in group FMR LLC More: the full row for FMR LLC 162,077 $1.88M <0.01% new 13F-HR Timeline Group Sio Capital Management, LLC More: the full row for Sio Capital Management, LLC 130,628 $1.51M 0.38% new 13F-HR Timeline TD Asset Management Inc More: the full row for TD Asset Management Inc 130,062 $1.51M <0.01% new 13F-HR Timeline Woodline Partners LP More: the full row for Woodline Partners LP 103,707 $1.2M 0.01% new 13F-HR Timeline MOORE CAPITAL MANAGEMENT, LP More: the full row for MOORE CAPITAL MANAGEMENT, LP 100,000 $1.16M 0.02% new 13F-HR Timeline BOOTHBAY FUND MANAGEMENT, LLC More: the full row for BOOTHBAY FUND MANAGEMENT, LLC 96,551 $1.12M 0.03% new 13F-HR Timeline NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 95,957 $1.11M <0.01% new 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 52,226 $605K <0.01% new 13F-HR Timeline Group XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 23,384 $271K 0.01% new 13F-HR Timeline Group China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 5,000 $57.9K <0.01% new 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 1,329 $15.4K <0.01% new 13F-HR/A Timeline Group MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 861 $9.97K <0.01% new 13F-HR/A Timeline Group FNY Investment Advisers, LLC More: the full row for FNY Investment Advisers, LLC 100 $1K <0.01% new 13F-HR Timeline ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 16 $0 0% new 13F-HR Timeline Group Value filed as zero, left out of ratios.