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SECTORAL ASSET MANAGEMENT INC

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13F filer, CIK 1274413, MONTREAL, Quebec, Canada

SECTORAL ASSET MANAGEMENT INC reported $162,014,983 across 82 holdings for the quarter ended 2025-09-30, in a 13F-HR filed 2025-11-14. Its ten largest share positions make up 35.02% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001104659-25-112082

Period
2025-09-30
Reported value
$162M
Holdings
82
Top 10 weight
35.02%
New
4
Sold out
16

Largest buys vs the previous quarter

SecurityShares changeApprox. value
SInew+430,282$5.4M
GPCRadded+170,503$4.77M
XBInew+34,000$3.41M
ANABadded+110,585$3.39M
IMTXadded+228,224$1.94M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
LENZexited-977,245-$28.6M
MLYSreduced-348,530-$13.2M
RAPPreduced-136,380-$4.05M
PVLAreduced-46,500-$2.92M
REPLexited-231,650-$2.15M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q3 2025

Share positions as resolved from 13F-HR 0001104659-25-112082, largest first. % of portfolio is the value over $162,014,983, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
CTNMCONTINEUM THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 800,887 shares; 2024Q4: 800,787 shares; 2025Q1: 800,787 shares; 2025Q2: 800,787 shares; 2025Q3: 800,787 shares 800,787$9.41M5.81%0Timeline
LLYELI LILLY & COQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 10,996 shares; 2024Q4: 12,546 shares; 2025Q1: 9,416 shares; 2025Q2: 8,976 shares; 2025Q3: 9,376 shares 9,376$7.15M4.42%+400Timeline
GPCRSTRUCTURE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 24,395 shares; 2024Q4: 49,250 shares; 2025Q1: 33,695 shares; 2025Q2: 51,369 shares; 2025Q3: 221,872 shares 221,872$6.21M3.83%+170,503Timeline
ANABANAPTYSBIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 83,900 shares; 2025Q3: 194,485 shares 194,485$5.96M3.68%+110,585Timeline
SISHOULDER INNOVATIONS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 430,282 shares 430,282$5.4M3.33%newTimeline
RCUSARCUS BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 75,522 shares; 2024Q4: 69,552 shares; 2025Q1: 26,870 shares; 2025Q2: 257,270 shares; 2025Q3: 368,070 shares 368,070$5.01M3.09%+110,800Timeline
IMTXIMMATICS N.VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 332,270 shares; 2025Q3: 560,494 shares 560,494$4.78M2.95%+228,224Timeline
UNHUNITEDHEALTH GROUP INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 13,125 shares; 2024Q4: 14,625 shares; 2025Q1: 12,895 shares; 2025Q2: 16,745 shares; 2025Q3: 13,545 shares 13,545$4.68M2.89%-3,200Timeline
BCAXBICARA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 201,395 shares; 2025Q3: 266,495 shares 266,495$4.21M2.6%+65,100Timeline
ORICORIC PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 20,000 shares; 2025Q2: 231,485 shares; 2025Q3: 328,655 shares 328,655$3.94M2.43%+97,170Timeline
SLDBSOLID BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 421,580 shares; 2025Q3: 633,052 shares 633,052$3.91M2.41%+211,472Timeline
KURAKURA ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 323,572 shares; 2025Q3: 395,872 shares 395,872$3.5M2.16%+72,300Timeline
VTYXVENTYX BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 931,620 shares; 2025Q3: 1,107,267 shares 1,107,267$3.44M2.13%+175,647Timeline
ABBVABBVIE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 15,800 shares; 2024Q4: 18,800 shares; 2025Q1: 14,800 shares; 2025Q2: 14,800 shares; 2025Q3: 14,800 shares 14,800$3.43M2.12%0Timeline
MBXMBX BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 191,825 shares; 2025Q3: 194,898 shares 194,898$3.41M2.11%+3,073Timeline
XBISPDR SERIES TRUSTQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 34,000 shares 34,000$3.41M2.1%newTimeline
ZBIOZENAS BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 210,625 shares; 2025Q3: 152,025 shares 152,025$3.37M2.08%-58,600Timeline
PVLAPALVELLA THERAPEUTICS INC NEQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 95,615 shares; 2025Q3: 49,115 shares 49,115$3.08M1.9%-46,500Timeline
TECXTECTONIC THERAPEUTIC INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 98,970 shares; 2025Q3: 192,770 shares 192,770$3.02M1.87%+93,800Timeline
VRTXVERTEX PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 4,840 shares; 2024Q4: 3,670 shares; 2025Q1: 4,725 shares; 2025Q2: 6,945 shares; 2025Q3: 7,715 shares 7,715$3.02M1.86%+770Timeline
AMGNAMGEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 7,090 shares; 2024Q4: 12,550 shares; 2025Q1: 10,385 shares; 2025Q2: 11,270 shares; 2025Q3: 10,340 shares 10,340$2.92M1.8%-930Timeline
TILINSTIL BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 86,220 shares; 2025Q3: 161,380 shares 161,380$2.88M1.78%+75,160Timeline
ARGXARGENX SEQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,997 shares; 2024Q4: 3,430 shares; 2025Q1: 3,103 shares; 2025Q2: 4,085 shares; 2025Q3: 3,890 shares 3,890$2.87M1.77%-195Timeline
JNJJOHNSON & JOHNSONQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 25,900 shares; 2024Q4: 22,900 shares; 2025Q1: 21,800 shares; 2025Q2: 19,300 shares; 2025Q3: 15,300 shares 15,300$2.84M1.75%-4,000Timeline
ISRGINTUITIVE SURGICAL INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,050 shares; 2024Q4: 3,050 shares; 2025Q1: 5,250 shares; 2025Q2: 5,250 shares; 2025Q3: 5,750 shares 5,750$2.57M1.59%+500Timeline
ONCBEONE MEDICINES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,637 shares; 2024Q4: 2,010 shares; 2025Q1: 2,927 shares; 2025Q2: 7,716 shares; 2025Q3: 7,201 shares 7,201$2.45M1.51%-515Timeline
ABTABBOTT LABORATORIESQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 19,398 shares; 2024Q4: 24,398 shares; 2025Q1: 18,698 shares; 2025Q2: 15,198 shares; 2025Q3: 17,198 shares 17,198$2.3M1.42%+2,000Timeline
REGNREGENERON PHARMACEUTICALSQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 3,400 shares; 2024Q4: 3,400 shares; 2025Q1: 2,773 shares; 2025Q2: 2,773 shares; 2025Q3: 3,968 shares 3,968$2.23M1.38%+1,195Timeline
GILDGILEAD SCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 61,065 shares; 2024Q4: 51,310 shares; 2025Q1: 32,020 shares; 2025Q2: 19,690 shares; 2025Q3: 19,550 shares 19,550$2.17M1.34%-140Timeline
BSXBOSTON SCIENTIFIC CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 33,026 shares; 2024Q4: 32,526 shares; 2025Q1: 24,226 shares; 2025Q2: 21,126 shares; 2025Q3: 22,126 shares 22,126$2.16M1.33%+1,000Timeline
DHRDANAHER CORP DELQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 4,775 shares; 2024Q4: 7,275 shares; 2025Q1: 10,575 shares; 2025Q2: 10,575 shares; 2025Q3: 10,575 shares 10,575$2.1M1.3%0Timeline
PFEPFIZER INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 114,650 shares; 2024Q4: 77,650 shares; 2025Q1: 59,650 shares; 2025Q2: 77,150 shares; 2025Q3: 77,150 shares 77,150$1.97M1.21%0Timeline
INSMINSMED INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 9,681 shares; 2024Q4: 7,371 shares; 2025Q1: 15,230 shares; 2025Q2: 14,880 shares; 2025Q3: 13,425 shares 13,425$1.93M1.19%-1,455Timeline
TMOTHERMO FISHER SCIENTIFIC INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 5,250 shares; 2024Q4: 4,750 shares; 2025Q1: 3,250 shares; 2025Q2: 3,900 shares; 2025Q3: 3,900 shares 3,900$1.89M1.17%0Timeline
QUREUNIQURE NVQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 153,000 shares; 2024Q4: 71,500 shares; 2025Q1: 57,550 shares; 2025Q2: 55,450 shares; 2025Q3: 30,740 shares 30,740$1.79M1.11%-24,710Timeline
BNTXBIONTECH SEQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 13,155 shares; 2024Q4: 18,950 shares; 2025Q1: 17,175 shares; 2025Q2: 16,160 shares; 2025Q3: 17,660 shares 17,660$1.74M1.07%+1,500Timeline
SYKSTRYKER CORPORATIONQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 7,450 shares; 2024Q4: 6,400 shares; 2025Q1: 6,100 shares; 2025Q2: 3,900 shares; 2025Q3: 4,300 shares 4,300$1.59M0.98%+400Timeline
SMMTSUMMIT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 26,700 shares; 2024Q4: 30,000 shares; 2025Q1: 69,240 shares; 2025Q2: 65,220 shares; 2025Q3: 74,070 shares 74,070$1.53M0.94%+8,850Timeline
ALNYALNYLAM PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 9,690 shares; 2024Q4: 8,300 shares; 2025Q1: 5,205 shares; 2025Q2: 3,323 shares; 2025Q3: 3,273 shares 3,273$1.49M0.92%-50Timeline
AZNASTRAZENECA PLC-SPONS ADRQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 21,340 shares; 2024Q4: 14,650 shares; 2025Q1: 18,790 shares; 2025Q2: 18,640 shares; 2025Q3: 18,750 shares 18,750$1.44M0.89%+110Timeline
DXCMDEXCOM INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 10,700 shares; 2024Q4: not reported; 2025Q1: 15,000 shares; 2025Q2: 13,200 shares; 2025Q3: 20,700 shares 20,700$1.39M0.86%+7,500Timeline
MRKMERCK & CO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 24,000 shares; 2024Q4: 24,500 shares; 2025Q1: 26,900 shares; 2025Q2: 20,900 shares; 2025Q3: 16,400 shares 16,400$1.39M0.86%-4,500Timeline
BMRNBIOMARIN PHARMACEUTICAL INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 36,870 shares; 2024Q4: 29,400 shares; 2025Q1: 23,530 shares; 2025Q2: 23,530 shares; 2025Q3: 25,030 shares 25,030$1.36M0.84%+1,500Timeline
RAPPRAPPORT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 179,860 shares; 2025Q3: 43,480 shares 43,480$1.29M0.8%-136,380Timeline
MLYSMINERALYS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 329,513 shares; 2024Q4: 380,883 shares; 2025Q1: 370,513 shares; 2025Q2: 382,415 shares; 2025Q3: 33,885 shares 33,885$1.28M0.79%-348,530Timeline
SNDXSYNDAX PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 63,300 shares; 2025Q3: 79,430 shares 79,430$1.22M0.75%+16,130Timeline
EWEDWARDS LIFESCIENCES CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 25,850 shares; 2024Q4: 7,850 shares; 2025Q1: not reported; 2025Q2: 15,000 shares; 2025Q3: 15,000 shares 15,000$1.17M0.72%0Timeline
TARSTARSUS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 11,300 shares; 2024Q4: 20,300 shares; 2025Q1: 17,250 shares; 2025Q2: 18,535 shares; 2025Q3: 18,405 shares 18,405$1.09M0.68%-130Timeline
MERUS N VMERUS N VQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 15,675 shares; 2025Q3: 11,545 shares 11,545$1.09M0.67%-4,130
TRVITREVI THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 81,800 shares; 2025Q2: 134,150 shares; 2025Q3: 105,950 shares 105,950$969K0.6%-28,200Timeline
ALHCALIGNMENT HEALTHCARE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 54,500 shares 54,500$951K0.59%newTimeline
FOLDAMICUS THERAPEUTICQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 141,335 shares; 2024Q4: 135,620 shares; 2025Q1: 107,585 shares; 2025Q2: 119,585 shares; 2025Q3: 119,105 shares 119,105$939K0.58%-480Timeline
PRVAPRIVIA HEALTH GROUP INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 52,000 shares; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 36,500 shares 36,500$909K0.56%newTimeline
VERAVERA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 7,428 shares; 2024Q4: 5,700 shares; 2025Q1: 28,348 shares; 2025Q2: 41,418 shares; 2025Q3: 30,188 shares 30,188$877K0.54%-11,230Timeline
BOLDBOUNDLESS BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 678,574 shares; 2024Q4: 678,574 shares; 2025Q1: 678,574 shares; 2025Q2: 678,574 shares; 2025Q3: 678,574 shares 678,574$835K0.52%0Timeline
SPRYARS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 98,640 shares; 2024Q4: 106,007 shares; 2025Q1: 100,205 shares; 2025Q2: 65,785 shares; 2025Q3: 81,785 shares 81,785$822K0.51%+16,000Timeline
RDNTRADNET INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 20,000 shares; 2025Q2: 12,500 shares; 2025Q3: 10,000 shares 10,000$762K0.47%-2,500Timeline
ROIVROIVANT SCIENCES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 45,127 shares; 2024Q4: 34,500 shares; 2025Q1: 48,907 shares; 2025Q2: 50,007 shares; 2025Q3: 50,007 shares 50,007$757K0.47%0Timeline
AVBPARRIVENT BIOPHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 10,090 shares; 2025Q2: 35,580 shares; 2025Q3: 39,235 shares 39,235$724K0.45%+3,655Timeline
ASNDASCENDIS PHARMA A/SQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,141 shares; 2024Q4: 1,600 shares; 2025Q1: 2,091 shares; 2025Q2: 3,471 shares; 2025Q3: 3,601 shares 3,601$716K0.44%+130Timeline
BBIOBRIDGEBIO PHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 15,085 shares; 2024Q4: 11,500 shares; 2025Q1: 16,085 shares; 2025Q2: 16,085 shares; 2025Q3: 13,650 shares 13,650$709K0.44%-2,435Timeline
OMDAOMADA HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 34,500 shares; 2025Q3: 27,500 shares 27,500$608K0.38%-7,000Timeline
IONSIONIS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 9,440 shares; 2024Q4: 7,200 shares; 2025Q1: 9,440 shares; 2025Q2: 9,205 shares; 2025Q3: 9,205 shares 9,205$602K0.37%0Timeline
CYTKCYTOKINETICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 28,593 shares; 2024Q4: 24,500 shares; 2025Q1: 18,068 shares; 2025Q2: 11,723 shares; 2025Q3: 10,223 shares 10,223$562K0.35%-1,500Timeline
HNGEHINGE HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 9,206 shares; 2025Q3: 11,206 shares 11,206$550K0.34%+2,000Timeline
PTCTPTC THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 7,600 shares; 2024Q4: 5,800 shares; 2025Q1: 8,350 shares; 2025Q2: 8,535 shares; 2025Q3: 8,535 shares 8,535$524K0.32%0Timeline
CITHE CIGNA GROUPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 2,250 shares; 2025Q1: not reported; 2025Q2: 1,800 shares; 2025Q3: 1,800 shares 1,800$519K0.32%0Timeline
BMYBRISTOL-MYERS SQUIBB COQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 50,000 shares; 2024Q4: 44,000 shares; 2025Q1: 19,500 shares; 2025Q2: 10,800 shares; 2025Q3: 10,800 shares 10,800$487K0.3%0Timeline
ZLABZAI LAB LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 72,870 shares; 2024Q4: 44,800 shares; 2025Q1: 29,920 shares; 2025Q2: 15,840 shares; 2025Q3: 12,590 shares 12,590$427K0.26%-3,250Timeline
NBIXNEUROCRINE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 12,515 shares; 2024Q4: 11,800 shares; 2025Q1: 2,905 shares; 2025Q2: 2,960 shares; 2025Q3: 2,960 shares 2,960$416K0.26%0Timeline
MDGLMADRIGAL PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,045 shares; 2024Q4: 570 shares; 2025Q1: 730 shares; 2025Q2: 730 shares; 2025Q3: 730 shares 730$335K0.21%0Timeline
BIIBBIOGEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 6,027 shares; 2024Q4: 3,852 shares; 2025Q1: 2,855 shares; 2025Q2: 2,375 shares; 2025Q3: 2,375 shares 2,375$333K0.21%0Timeline
RPRXROYALTY PHARMA PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 16,430 shares; 2024Q4: 7,200 shares; 2025Q1: 9,280 shares; 2025Q2: 9,280 shares; 2025Q3: 9,280 shares 9,280$327K0.2%0Timeline
UTHRUNITED THERAPEUTICS CORP DELQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 1,060 shares; 2024Q4: 595 shares; 2025Q1: 765 shares; 2025Q2: 765 shares; 2025Q3: 765 shares 765$321K0.2%0Timeline
TEMTEMPUS AI INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 2,160 shares; 2025Q2: 3,760 shares; 2025Q3: 3,760 shares 3,760$303K0.19%0Timeline
JAZZJAZZ PHARMACEUTICALS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 2,274 shares; 2024Q4: 1,750 shares; 2025Q1: 2,274 shares; 2025Q2: 2,274 shares; 2025Q3: 2,244 shares 2,244$296K0.18%-30Timeline
ILMNILLUMINA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 5,745 shares; 2024Q4: 4,370 shares; 2025Q1: 3,682 shares; 2025Q2: 2,782 shares; 2025Q3: 2,727 shares 2,727$259K0.16%-55Timeline
INCYINCYTE CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 2,500 shares; 2025Q1: 6,145 shares; 2025Q2: 6,060 shares; 2025Q3: 3,030 shares 3,030$257K0.16%-3,030Timeline
PCVXVAXCYTE INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 14,540 shares; 2024Q4: 18,950 shares; 2025Q1: 21,040 shares; 2025Q2: 4,205 shares; 2025Q3: 4,205 shares 4,205$151K0.09%0Timeline
MRNAMODERNA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 13,960 shares; 2024Q4: 4,350 shares; 2025Q1: 5,600 shares; 2025Q2: 5,600 shares; 2025Q3: 5,600 shares 5,600$145K0.09%0Timeline
AXSMAXSOME THERAPEUTICS INC.Quarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: 820 shares; 2025Q1: 1,020 shares; 2025Q2: 1,020 shares; 2025Q3: 1,020 shares 1,020$124K0.08%0Timeline
MLTXMOONLAKE IMMUNOTHERAPEUTICSQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: 27,258 shares; 2024Q4: 23,687 shares; 2025Q1: 15,108 shares; 2025Q2: 15,108 shares; 2025Q3: 956 shares 956$6.86K<0.01%-14,152Timeline

Sold out in Q3 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
LENZLENZ THERAPEUTICS INC977,245$28.6Mshares
REPLREPLIMUNE GROUP INC231,650$2.15Mshares
Tourmaline Bio IncTourmaline Bio Inc116,510$1.86Mshares
GMEDGLOBUS MED INC13,500$797Kshares
LEGNLEGEND BIOTECH CORP19,627$697Kshares
CNCCENTENE CORP DEL12,500$678Kshares
KMTSKESTRA MED TECHNOLOGIES LTD35,000$580Kshares
CVRXCVRX INC73,500$432Kshares
SRRKSCHOLAR ROCK HLDG CORP10,380$368Kshares
RVMDREVOLUTION MEDICINES INC6,240$230Kshares
CAICARIS LIFE SCIENCES INC8,350$223Kshares
VTRSVIATRIS INC19,800$177Kshares
MEDPMEDPACE HLDGS INC531$167Kshares
IOBTQIO BIOTECH INC117,691$164Kshares
CRSPCRISPR THERAPEUTICS AG2,540$124Kshares
RXRXRECURSION PHARMACEUTICALS IN11,500$58.2Kshares

How Q3 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001104659-25-112082 base2025-11-14acceptance time not in the bulk data set