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Disclosery

Opaleye Management Inc.: ZYME position timeline

Available 13F reports, 13D and 13G stakes and each Form 3, 4 and 5 line of Opaleye Management Inc. on ZYME, newest first. How the timeline and the estimate are built.

Opaleye Management Inc. held 0 ZYME shares at 2026-03-31 per its 13F-HR filed 2026-05-15.

the latest 13F is the newest step

  1. period ended2026-03-31
    13F 0 shares
    Change vs previous 13F -108,929 shares

    13F-HR 0001420506-26-001151 filed by Opaleye Management Inc.
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

    Exited: the 13F for this period no longer lists the position.

  2. period ended2025-12-31
    13F/A 108,929 shares
    Change vs previous 13F +8,929 shares

    0.38% of the 13F portfolio, value $2,868,101.

    13F-HR/A 0001493152-26-016299 filed by Opaleye Management Inc.
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  3. period ended2025-09-30
    13F 100,000 shares
    Change vs previous 13F -110,000 shares

    0.24% of the 13F portfolio, value $1,708,000.

    13F-HR 0001493152-25-023429 filed by Opaleye Management Inc.
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  4. period ended2025-06-30
    13F/A 210,000 shares
    Change vs previous 13F +35,000 shares

    0.53% of the 13F portfolio, value $2,635,500.

    13F-HR/A 0001641172-25-024301 filed by Opaleye Management Inc.
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  5. period ended2025-03-31
    13F 175,000 shares
    Change vs previous 13F not available

    0.46% of the 13F portfolio, value $2,084,250.

    13F-HR 0001641172-25-010914 filed by Opaleye Management Inc.
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).