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Foresite Capital Management VI LLC

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13F filer, CIK 2013341, WEST HOLLYWOOD, CA

Foresite Capital Management VI LLC reported $460,271,345 across 17 holdings for the quarter ended 2026-03-31, in a 13F-HR filed 2026-05-15. Its ten largest share positions make up 90.54% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001104659-26-062467

Period
2026-03-31
Reported value
$460M
Holdings
17
Top 10 weight
90.54%
New
8
Sold out
3

Part of the filer group Foresite Capital Management VI LLC

How groups are built

Largest buys vs the previous quarter

SecurityShares changeApprox. value
NERVnew+1,986,600$12M
CLDXnew+315,913$10M
ATAInew+2,750,000$9.73M
CRNXnew+212,010$7.7M
CRVSadded+450,000$6.58M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
RAPTexited-1,562,500-$52.9M
NTRAexited-67,356-$15.4M
ATAIBECKLEY INCexited-2,750,000-$11.2M
AGIOreduced-5,000-$169K

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q1 2026

Share positions as resolved from 13F-HR 0001104659-26-062467, largest first. % of portfolio is the value over $460,271,345, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
CGONCG ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 2,221,474 shares; 2025Q1: 2,221,474 shares; 2025Q2: 2,221,474 shares; 2025Q3: 2,221,474 shares; 2025Q4: 2,221,474 shares; 2026Q1: 2,221,474 shares 2,221,474$150M32.67%0Timeline
ALMSALUMIS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 4,202,670 shares; 2025Q1: 4,202,670 shares; 2025Q2: 4,247,670 shares; 2025Q3: 4,247,670 shares; 2025Q4: 4,247,670 shares; 2026Q1: 4,247,670 shares 4,247,670$93.6M20.33%0Timeline
CNTACENTESSA PHARMACEUTICALS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 1,253,379 shares; 2025Q1: 1,253,379 shares; 2025Q2: 1,253,379 shares; 2025Q3: 1,314,019 shares; 2025Q4: 1,364,019 shares; 2026Q1: 1,364,019 shares 1,364,019$54.2M11.77%0Timeline
CRVSCORVUS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 1,581,233 shares; 2025Q1: 1,581,233 shares; 2025Q2: 1,731,233 shares; 2025Q3: 1,731,233 shares; 2025Q4: 1,381,233 shares; 2026Q1: 1,831,233 shares 1,831,233$26.8M5.82%+450,000Timeline
DNLIDENALI THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,000,000 shares; 2025Q4: 1,000,000 shares; 2026Q1: 1,209,971 shares 1,209,971$23.2M5.05%+209,971Timeline
AGIOAGIOS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 530,000 shares; 2026Q1: 525,000 shares 525,000$17.8M3.86%-5,000Timeline
VSTMVERASTEM INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 1,276,520 shares; 2025Q3: 2,615,120 shares; 2025Q4: 3,135,120 shares; 2026Q1: 3,146,631 shares 3,146,631$16.7M3.62%+11,511Timeline
KYMRKYMERA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: 146,332 shares; 2025Q1: 146,332 shares; 2025Q2: 146,332 shares; 2025Q3: 146,332 shares; 2025Q4: 146,332 shares; 2026Q1: 146,332 shares 146,332$12.2M2.65%0Timeline
NERVMINERVA NEUROSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 1,986,600 shares 1,986,600$12M2.6%newTimeline
CLDXCELLDEX THERAPEUTICS INC NEWQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 315,913 shares 315,913$10M2.18%newTimeline
ATAIATAIBECKLEY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 2,750,000 shares 2,750,000$9.73M2.12%newTimeline
HNGEHINGE HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: 135,000 shares; 2025Q3: 135,000 shares; 2025Q4: 135,000 shares; 2026Q1: 220,400 shares 220,400$8.5M1.85%+85,400Timeline
CRNXCRINETICS PHARMACEUTICALS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 212,010 shares 212,010$7.7M1.67%newTimeline
OKURONKURE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 1,445,783 shares 1,445,783$5.99M1.3%newTimeline
JBIOJADE BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 320,000 shares 320,000$4.5M0.98%newTimeline
GHRSGH RESEARCH PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 315,492 shares 315,492$4.44M0.96%newTimeline
ZURAZURA BIO LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: not reported; 2026Q1: 450,000 shares 450,000$2.68M0.58%newTimeline

Sold out in Q1 2026

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
RAPTRAPT THERAPEUTICS INC1,562,500$52.9Mshares
NTRANATERA INC67,356$15.4Mshares
ATAIBECKLEY INCATAIBECKLEY INC2,750,000$11.2Mshares

How Q1 2026 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001104659-26-062467 base2026-05-15acceptance time not in the bulk data set