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Disclosery

XERS XERIS BIOPHARMA HOLDINGS INC

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COM (common), issuer CIK 1867096

220 managers (224 13F filers) reported a position in XERS shares at 2025-12-31, 100,812,097 shares in all. 30 filers opened a position and 40 filers sold out during the quarter.

Managers
220
13F filers
224
New
30
Added
79
Reduced
76
Sold out
40
Shares held by filers
100,812,097

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
BlackRock, Inc.in group BlackRock, Inc.12,639,318$99.2M<0.01%+711,61913F-HRTimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding11,186,677$87.8M+1,343,199Timeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.7,574,850$59.5M0.05%+1,734,96413F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC4,275,989$33.6M<0.01%+135,81513F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP4,116,924$32.3M<0.01%+378,59513F-HRTimelineGroup
Qube Research & Technologies Ltd3,498,197$27.5M0.04%+223,36313F-HRTimeline
Driehaus Capital Management LLC2,980,567$23.4M0.16%+361,43813F-HRTimeline
Nuveen, LLCin group TIAA2,806,806$22M0.01%-21,06813F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY2,707,783$21.3M<0.01%-511,91813F-HR/ATimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding2,582,001$20.3M+74,180Timeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…2,286,598$17.9M<0.01%+1,705,63613F-HRTimelineGroup
Rosalind Advisors, Inc.2,111,700$16.6M6.04%+315,93413F-HRTimeline
Parkman Healthcare Partners LLC1,691,585$13.3M1.26%-100,08913F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC1,568,421$12.3M<0.01%-227,03413F-HR/ATimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co1,403,824$11M<0.01%-42,79513F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc1,396,265$11M<0.01%+38,83813F-HRTimelineGroup
CenterBook Partners LP1,391,590$10.9M0.53%+693,38613F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP1,386,829$10.9M<0.01%+23,70013F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding1,253,279$9.84M-712,914Timeline
Granahan Investment Management, LLC1,223,404$9.6M0.41%+873,23613F-HRTimeline
KENNEDY CAPITAL MANAGEMENT LLC1,213,969$9.53M0.2%+2,38613F-HRTimeline
Connor, Clark & Lunn Investment Managem…1,058,692$8.31M0.02%-640,06513F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC971,598$7.62M0.01%+50,49513F-HRTimelineGroup
Knott David M Jr970,000$7.61M3.53%-45,00013F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC957,579$7.52M<0.01%-26,02113F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\940,592$7.38M<0.01%-627,05313F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO895,059$7.03M<0.01%-10,01713F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC859,051$6.74M<0.01%+334,30213F-HRTimelineGroup
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.854,888$6.71M0.01%+150,50513F-HRTimelineGroup
VOLORIDGE INVESTMENT MANAGEMENT, LLC811,129$6.37M0.02%-223,42413F-HRTimeline
NORGES BANK800,700$6.29M<0.01%new13F-HRTimeline
Ishara Investments LP800,000$6.28M7.31%13F-HRTimeline
ESSEX INVESTMENT MANAGEMENT CO LLC734,532$5.77M0.88%-15,50213F-HRTimeline
ALGERT GLOBAL LLC718,844$5.64M0.09%+560,88413F-HR/ATimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/717,914$5.64M<0.01%-876,95213F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC619,660$4.86M0.01%-1,003,18013F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC618,949$4.86M0.01%-815,25513F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.608,080$4.77M0.01%new13F-HRTimelineGroup
HEALTHCARE OF ONTARIO PENSION PLAN TRUS…537,483$4.22M0.01%+283,48313F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC482,832$3.79M0.01%-196,24913F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC458,329$3.6M<0.01%+58,25013F-HRTimelineGroup
CASTLEARK MANAGEMENT LLC445,950$3.5M0.1%new13F-HRTimeline
FMR LLCin group FMR LLC439,705$3.45M<0.01%+79,52713F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp434,262$3.41M<0.01%-5,57613F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC409,820$3.22M<0.01%-27,79213F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO399,347$3.13M<0.01%+278,17113F-HRTimelineGroup
CANADA PENSION PLAN INVESTMENT BOARD390,600$3.07M<0.01%+14,90013F-HRTimeline
Voss Capital, LP371,709$2.92M0.16%new13F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…364,786$2.86M<0.01%+113,40813F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC362,751$2.85M<0.01%+16,11213F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD357,453$2.81M0.01%+6,92413F-HRTimeline
Jump Financial, LLCin group Jump Financial, LLC341,068$2.68M0.03%-262,17613F-HRTimelineGroup
HRT FINANCIAL LP332,326$2.61M0.01%+259,78313F-HRTimeline
Swiss National Bank318,400$2.5M<0.01%+8,00013F-HRTimeline
Harvest Investment Services, LLC292,677$2.3M0.43%-32,87813F-HRTimeline
IHT Wealth Management, LLC263,531$2.07M0.05%+5,35613F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS258,368$2.03M<0.01%-323,35113F-HRTimelineGroup
Apella Capital, LLC245,897$1.93M0.04%+235,89713F-HRTimeline
Legato Capital Management LLC237,431$1.86M0.16%+20,62613F-HRTimeline
Schonfeld Strategic Advisors LLC234,723$1.84M0.01%-69,78113F-HRTimeline
ARROWSTREET CAPITAL, LIMITED PARTNERSHIPin group ARROWSTREET CAPITAL, LIMITED …214,786$1.69M<0.01%new13F-HRTimelineGroup
Trexquant Investment LP213,581$1.68M0.01%-15,83913F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC211,419$1.66M<0.01%+6,20613F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC197,815$1.55M<0.01%+7213F-HRTimeline
RHUMBLINE ADVISERS189,567$1.49M<0.01%-24,17713F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC177,822$1.4M<0.01%-735,93613F-HRTimelineGroup
CAXTON ASSOCIATES LLP174,102$1.37M0.03%-107,23513F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/173,463$1.36M<0.01%+6,67513F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN170,796$1.34M<0.01%+73,60013F-HRTimelineGroup
DIADEMA PARTNERS LP170,568$1.34M0.8%+95,81513F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…151,171$1.19M<0.01%-71513F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC150,559$1.18M<0.01%+45,06613F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.144,830$1.14M<0.01%013F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC143,463$1.13M<0.01%-10,70513F-HRTimelineGroup
POLEN CAPITAL MANAGEMENT LLC133,416$1.05M<0.01%+22513F-HRTimeline
GROUP ONE TRADING LLC123,561$970K0.03%+117,53713F-HRTimeline
GLOBEFLEX CAPITAL L P123,184$967K0.15%013F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources121,428$953K<0.01%+12,28613F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding117,355$921K+18,797Timeline
Creative Planningin group Creative Planning116,538$915K<0.01%-10,44213F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.112,130$880K<0.01%-470,97813F-HRTimelineGroup
SG Americas Securities, LLC110,180$865K<0.01%+26,96613F-HRTimeline
Faithward Advisors, LLC106,730$838K0.12%new13F-HRTimeline
THOMPSON SIEGEL & WALMSLEY LLC100,884$792K0.01%013F-HRTimeline
Resolute Capital Asset Partners LLC100,000$785K0.38%new13F-HRTimeline
Calamos Advisors LLCin group Calamos Advisors LLC99,117$778K<0.01%-37,98013F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC98,746$775K<0.01%+28,49113F-HRTimelineGroup
Round Rock Advisors LLC96,816$760K0.11%+33,04413F-HR/ATimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…92,416$725K0.01%-39,74413F-HRTimelineGroup
Y-Intercept (Hong Kong) Ltd90,645$712K0.02%+8,46413F-HRTimeline
Engineers Gate Manager LP89,404$702K0.01%-20,59013F-HRTimeline
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.87,800$689K0.01%new13F-HRTimelineGroup
IEQ CAPITAL, LLC86,520$679K<0.01%-21,43313F-HRTimeline
LPL Financial LLC84,861$666K<0.01%+51,55913F-HRTimeline
Informed Momentum Co LLC80,154$629K0.07%-522,94713F-HRTimeline
Quarry LP80,000$628K0.1%-2,50013F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding79,374$623K+1,800Timeline
Quantbot Technologies LP77,648$610K0.02%+8,28313F-HRTimeline
Western Wealth Management, LLC75,675$594K0.03%new13F-HRTimeline
TEACHERS RETIREMENT SYSTEM OF THE STATE…72,907$572K<0.01%new13F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson69,887$548K<0.01%013F-HRTimelineGroup
EntryPoint Capital, LLC68,083$534K0.21%+15,06813F-HRTimeline
Integrated Quantitative Investments LLC66,170$519K0.11%new13F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…65,767$516K<0.01%+33,11513F-HRTimeline
STRS OHIO65,500$514K<0.01%013F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC65,090$511K<0.01%+9,75413F-HRTimeline
WINTON GROUP Ltdin group WINTON GROUP Ltd64,597$507K0.02%-26,19613F-HRTimelineGroup
CWM, LLCin group CWM, LLC55,356$435K<0.01%-8313F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.52,285$410K<0.01%+11,93413F-HRTimelineGroup
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…52,230$410K0.01%-68,67013F-HRTimelineGroup
DARK FOREST CAPITAL MANAGEMENT LP52,043$409K0.02%-84,68813F-HRTimeline
Weiss Asset Management LPin group Weiss Asset Management LP50,001$393K0.01%013F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
Penn Capital Management Company, LLC48,064$377K0.03%new13F-HRTimeline
Man Group plcin group Man Group plc47,775$375K<0.01%new13F-HRTimelineGroup
Campbell & CO Investment Adviser LLC47,454$373K0.02%-56,16213F-HRTimeline
AXQ CAPITAL, LP46,454$365K0.08%+20,09813F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …45,801$360K<0.01%-4,34313F-HRTimelineGroup
Persistent Asset Partners Ltd45,609$358K0.17%+28,40713F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM45,269$355K<0.01%-2,09313F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND43,422$341K<0.01%013F-HRTimeline
AlphaCentric Advisors LLC43,392$341K0.34%13F-HRTimeline
State of Wyoming42,458$333K0.04%+29,55813F-HRTimeline
LJI Wealth Management, LLC42,350$332K0.05%013F-HRTimeline
Police & Firemen's Retirement System of…40,738$320K<0.01%-62413F-HRTimeline
Savvy Advisors, Inc.40,465$318K0.01%013F-HRTimeline
PROFUND ADVISORS LLC38,947$306K0.01%+12,38313F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA38,636$304K<0.01%+2,35113F-HRTimelineGroup
Cetera Investment Advisers38,647$303K<0.01%-1,37113F-HRTimeline
STATE BOARD OF ADMINISTRATION OF FLORID…37,970$298K<0.01%013F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…37,102$291K0.08%+11,35813F-HRTimelineGroup
Ausbil Investment Management Ltd37,000$290K0.17%new13F-HRTimeline
Gotham Asset Management, LLC35,412$278K<0.01%-7,32913F-HRTimeline
ProShare Advisors LLC35,390$278K<0.01%+3,38313F-HRTimeline
GSA CAPITAL PARTNERS LLP34,665$272K0.02%-34,05113F-HRTimeline
Cambridge Investment Research Advisors,…34,642$272K<0.01%013F-HRTimeline
Rafferty Asset Management, LLC33,689$264K<0.01%+16,27813F-HRTimeline
KLP KAPITALFORVALTNING AS33,400$262K<0.01%013F-HRTimeline
DIVERSIFIED TRUST CO32,062$252K<0.01%013F-HRTimeline
VARCOV Co.31,005$243K0.1%13F-HRTimeline
Cerity Partners LLCin group Cerity Partners LLC29,578$232K<0.01%-1,45513F-HRTimelineGroup
WEALTH ENHANCEMENT ADVISORY SERVICES, L…31,105$216K<0.01%-213F-HRTimeline
China Universal Asset Management Co., L…27,037$212K0.02%-1,26813F-HRTimeline
Asset Management Group, Inc.26,480$208K0.03%013F-HRTimeline
FOX RUN MANAGEMENT, L.L.C.26,174$205K0.03%new13F-HRTimeline
Swiss Life Asset Management Ltdin group Swiss Life Asset Management L…26,059$205K<0.01%new13F-HRTimelineGroup
9823 Capital, L.P.24,917$196K0.13%13F-HRTimeline
Quantinno Capital Management LP24,696$194K<0.01%+7,00213F-HRTimeline
Janney Montgomery Scott LLC24,450$192K<0.01%-1,75013F-HRTimeline
Palumbo Wealth Management LLC24,349$191K0.05%-38,84013F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS23,936$188K<0.01%-15,38513F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…23,196$182K<0.01%013F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL22,186$174K<0.01%-15,80813F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC17,901$174K<0.01%013F-HRTimeline
Van Hulzen Asset Management, LLC20,382$160K0.01%-1,80013F-HRTimeline
ASPIRIANT, LLC20,000$157K<0.01%013F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC17,840$140K<0.01%+58513F-HRTimeline
Modern Wealth Management, LLC17,712$139K<0.01%+813F-HRTimeline
Dynamic Technology Lab Private Ltd17,200$135K0.03%new13F-HRTimeline
Numerai GP LLC17,148$135K0.02%-1,35913F-HRTimeline
Jacksonville Wealth Management, LLC17,000$133K0.09%013F-HRTimeline
CIBC Bancorp USA Inc.group of 2 filers holding16,822$132K+10,158Timeline
Empirical Financial Services, LLC d.b.a…16,070$126K<0.01%+2,42013F-HRTimeline
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.in group LANDSCAPE CAPITAL MANAGEMENT,…15,709$123K0.01%013F-HRTimelineGroup
BAILARD, INC.15,300$120K<0.01%new13F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …14,192$111K<0.01%+1,03713F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…12,827$101K<0.01%013F-HRTimelineGroup
Aigen Investment Management, LP12,262$96.3K0.02%-6,86713F-HRTimeline
XPONANCE LLC12,112$95.1K<0.01%+12713F-HRTimeline
CAPTRUST FINANCIAL ADVISORS11,816$92.8K<0.01%-8813F-HRTimeline
Brooklyn Investment Group12,195$90.6K<0.01%new13F-HRTimeline
O'SHAUGHNESSY ASSET MANAGEMENT, LLC11,423$89.7K<0.01%+1,26313F-HRTimeline
Jain Global LLC11,114$87.2K<0.01%new13F-HRTimeline
Pallas Capital Advisors LLC11,003$86.4K<0.01%-2413F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…10,740$84.3K<0.01%+6,28613F-HRTimelineGroup
Kingsview Wealth Management, LLC10,000$78.5K<0.01%new13F-HRTimeline
Kemnay Advisory Services Inc.8,480$66.6K0.01%new13F-HRTimeline
State of Alaska, Department of Revenue8,457$66K<0.01%013F-HRTimeline
Truvestments Capital LLC8,118$63.7K0.01%+3,97913F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP5,707$44.8K<0.01%+2,92613F-HRTimelineGroup
AMALGAMATED BANK4,824$38K<0.01%-1013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.3,260$25.6K<0.01%-21413F-HRTimeline
Kestra Advisory Services, LLCin group Kestra Advisory Services, LLC3,192$25.1K<0.01%new13F-HRTimelineGroup
WEBSTER BANK, N. A.3,000$23.6K<0.01%-1,00013F-HRTimeline
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…2,821$22.1K<0.01%-4,96813F-HR/ATimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…2,818$22.1K<0.01%+94113F-HRTimelineGroup
Farther Finance Advisors, LLC2,571$20.2K<0.01%+19013F-HRTimeline
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …2,353$18K<0.01%new13F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC2,204$17.3K<0.01%013F-HRTimeline
CREATIVE FINANCIAL DESIGNS INC /ADV2,200$17.3K<0.01%013F-HRTimeline
SBI Securities Co., Ltd.1,907$15K<0.01%-613F-HRTimeline
Caitong International Asset Management …1,714$13.5K<0.01%+1,63413F-HR/ATimeline
Arax Advisory Partners1,632$12.8K<0.01%-14,22713F-HRTimeline
Fortitude Family Office, LLC1,553$12.2K<0.01%013F-HRTimeline
Essential Partners LLC1,288$10.1K<0.01%-13913F-HRTimeline
AlphaQuest LLC1,204$9.45K<0.01%-3,09613F-HRTimeline
Sound Income Strategies, LLC1,149$8.64K<0.01%new13F-HRTimeline
Sterling Capital Management LLC1,020$8.01K<0.01%+64813F-HRTimeline
True Wealth Design, LLC1,011$7.94K<0.01%013F-HRTimeline
Hillsdale Investment Management Inc.1,000$7.85K<0.01%013F-HRTimeline
Activest Wealth Management1,000$7.85K<0.01%013F-HRTimeline