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Disclosery

XERS XERIS BIOPHARMA HOLDINGS INC

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COM (common), issuer CIK 1867096

224 managers (230 13F filers) reported a position in XERS shares at 2025-09-30, 96,876,870 shares in all. 58 filers opened a position and 28 filers sold out during the quarter.

Managers
224
13F filers
230
New
58
Added
77
Reduced
61
Sold out
28
Shares held by filers
96,876,870

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
BlackRock, Inc.in group BlackRock, Inc.11,927,699$97.1M<0.01%+391,37813F-HRTimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding9,843,478$80.1M+26,541Timeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.5,839,886$47.5M0.04%+2,004,47913F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC4,140,174$33.7M<0.01%+489,48613F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP3,738,329$30.4M<0.01%-44,87113F-HRTimelineGroup
Qube Research & Technologies Ltd3,274,834$26.7M0.04%+185,06313F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY3,219,701$26.2M<0.01%-422,88313F-HR/ATimelineGroup
Nuveen, LLCin group TIAA2,827,874$23M0.01%+227,43213F-HRTimelineGroup
Driehaus Capital Management LLC2,619,129$21.3M0.15%+548,05413F-HRTimeline
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding2,507,821$20.4M+236,343Timeline
UBS Group AGgroup of 2 filers holding1,966,193$16M+1,700,709Timeline
Rosalind Advisors, Inc.1,795,766$14.6M5.17%-359,82813F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC1,795,455$14.6M<0.01%-476,03113F-HRTimelineGroup
Parkman Healthcare Partners LLC1,791,674$14.6M1.6%-315,80913F-HRTimeline
Connor, Clark & Lunn Investment Managem…1,698,757$13.8M0.04%+470,79813F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC1,622,840$13.2M0.02%-432,50013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/1,594,866$13M<0.01%-68,62413F-HR/ATimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\1,567,645$12.8M<0.01%+830,71813F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co1,446,619$11.8M<0.01%+879,08113F-HRTimelineGroup
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC1,434,204$11.7M0.01%-122,42513F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP1,363,129$11.1M<0.01%+69,59913F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc1,357,427$11M<0.01%-446,77613F-HRTimelineGroup
KENNEDY CAPITAL MANAGEMENT LLC1,211,583$9.86M0.22%+395,43613F-HRTimeline
VOLORIDGE INVESTMENT MANAGEMENT, LLC1,034,553$8.42M0.03%+40,17213F-HRTimeline
Knott David M Jr1,015,000$8.26M3.46%-45,00013F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC983,600$8.01M0.01%-65,39313F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC921,103$7.5M0.01%+537,86613F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC913,758$7.44M0.01%+882,59313F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO905,076$7.37M<0.01%-127,18613F-HR/ATimelineGroup
ESSEX INVESTMENT MANAGEMENT CO LLC750,034$6.11M0.93%+24,26013F-HRTimeline
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.704,383$5.73M0.01%+13,00213F-HRTimelineGroup
CenterBook Partners LP698,204$5.68M0.28%-896,02513F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC679,081$5.53M0.01%+394,51413F-HRTimelineGroup
Walleye Capital LLCin group Walleye Capital LLC623,962$5.08M0.04%+380,68713F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC603,244$4.91M0.06%-153,15913F-HR/ATimelineGroup
Informed Momentum Co LLC603,101$4.85M0.56%+16,23613F-HRTimeline
Invesco Ltd.in group Invesco Ltd.583,108$4.75M<0.01%+496,91413F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS581,719$4.74M<0.01%+565,40913F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…580,962$4.73M<0.01%+181,67113F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC524,749$4.27M<0.01%-2,408,87113F-HRTimelineGroup
Redmile Group, LLCin group Redmile Group, LLC451,099$3.67M0.36%013F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp439,838$3.58M<0.01%+62,71113F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC437,612$3.56M<0.01%new13F-HRTimelineGroup
Divisadero Street Capital Management, LPin group Divisadero Street Capital Man…406,334$3.31M0.15%new13F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC400,079$3.26M<0.01%+358,68913F-HRTimelineGroup
CANADA PENSION PLAN INVESTMENT BOARD375,700$3.06M<0.01%new13F-HRTimeline
FMR LLCin group FMR LLC360,178$2.93M<0.01%+33,75813F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD350,529$2.85M0.01%+72,50913F-HRTimeline
Granahan Investment Management, LLC350,168$2.85M0.12%new13F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC346,639$2.82M<0.01%-77,60913F-HR/ATimelineGroup
Harvest Investment Services, LLC325,555$2.65M0.53%+213,58513F-HRTimeline
Swiss National Bank310,400$2.53M<0.01%new13F-HRTimeline
Schonfeld Strategic Advisors LLC304,504$2.48M0.02%-84,56213F-HRTimeline
CAXTON ASSOCIATES LLP281,337$2.29M0.06%new13F-HRTimeline
IHT Wealth Management, LLC258,175$2.1M0.05%-5,63013F-HRTimeline
HEALTHCARE OF ONTARIO PENSION PLAN TRUS…254,000$2.07M<0.01%+2,00013F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…251,378$2.05M<0.01%+128,18913F-HRTimelineGroup
Trexquant Investment LP229,420$1.87M0.02%new13F-HRTimeline
Legato Capital Management LLC216,805$1.76M0.19%013F-HRTimeline
RHUMBLINE ADVISERS213,744$1.74M<0.01%-1,94713F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC205,213$1.67M<0.01%-3,93313F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC197,743$1.61M<0.01%013F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/166,788$1.36M<0.01%+13,51713F-HRTimeline
ALGERT GLOBAL LLC157,960$1.29M0.02%new13F-HR/ATimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC154,168$1.25M<0.01%+5,14013F-HRTimelineGroup
MACKENZIE FINANCIAL CORP152,161$1.24M<0.01%+14,06913F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…151,886$1.24M<0.01%+141,72513F-HRTimeline
ALLIANCEBERNSTEIN L.P.144,830$1.18M<0.01%013F-HRTimeline
Calamos Advisors LLCin group Calamos Advisors LLC137,097$1.12M<0.01%new13F-HRTimelineGroup
DARK FOREST CAPITAL MANAGEMENT LP136,731$1.11M0.04%new13F-HR/ATimeline
POLEN CAPITAL MANAGEMENT LLC133,191$1.08M<0.01%+19713F-HRTimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…132,160$1.08M0.02%-72,86413F-HRTimelineGroup
Inspire Investing, LLCin group Inspire Investing, LLC128,494$1.05M0.1%new13F-HRTimelineGroup
Creative Planningin group Creative Planning126,980$1.03M<0.01%+9,22513F-HRTimelineGroup
GLOBEFLEX CAPITAL L P123,184$1M0.15%+42,75313F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO121,176$986K<0.01%+4,64213F-HRTimelineGroup
DEERFIELD MANAGEMENT COMPANY, L.P.in group DEERFIELD MANAGEMENT COMPANY,…120,900$984K0.02%+98,32613F-HRTimelineGroup
Roundview Capital LLC120,000$977K0.06%013F-HRTimeline
Engineers Gate Manager LP109,994$895K0.01%+71,95413F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources109,142$888K<0.01%+5,86413F-HRTimelineGroup
FRED ALGER MANAGEMENT, LLCin group FRED ALGER MANAGEMENT, LLC108,936$887K<0.01%new13F-HRTimelineGroup
IEQ CAPITAL, LLC107,953$879K<0.01%-54213F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC105,493$859K<0.01%-48,44413F-HRTimelineGroup
Campbell & CO Investment Adviser LLC103,616$843K0.06%-28,76613F-HRTimeline
THOMPSON SIEGEL & WALMSLEY LLC100,884$821K0.01%-165,50313F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding98,558$802K-324,731Timeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN97,196$791K<0.01%+16,83013F-HRTimelineGroup
WINTON GROUP Ltdin group WINTON GROUP Ltd90,793$739K0.03%new13F-HRTimelineGroup
ExodusPoint Capital Management, LP86,920$708K0.01%new13F-HRTimeline
SG Americas Securities, LLC83,214$677K<0.01%+63,92113F-HRTimeline
Aquatic Capital Management LLC83,000$676K0.01%new13F-HRTimeline
Quarry LP82,500$672K0.16%-80,00013F-HRTimeline
Y-Intercept (Hong Kong) Ltd82,181$669K0.02%-254,03313F-HRTimeline
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC80,420$655K0.02%013F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding77,574$631K-10,751Timeline
DIADEMA PARTNERS LP74,753$608K0.42%new13F-HRTimeline
HRT FINANCIAL LP72,543$590K<0.01%new13F-HRTimeline
Round Rock Advisors LLC63,772$582K0.09%new13F-HRTimeline
Bayesian Capital Management, LP70,800$576K0.12%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC70,255$572K<0.01%-7,27913F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson69,887$569K<0.01%new13F-HRTimelineGroup
Quantbot Technologies LP69,365$565K0.02%+26,42013F-HRTimeline
GSA CAPITAL PARTNERS LLP68,716$559K0.05%+6,39413F-HRTimeline
STRS OHIO65,500$533K<0.01%013F-HRTimeline
GPS Wealth Strategies Group, LLC65,089$530K0.06%+16413F-HRTimeline
Palumbo Wealth Management LLC63,189$514K0.16%new13F-HRTimeline
CWM, LLCin group CWM, LLC55,439$451K<0.01%+32813F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC55,336$450K<0.01%-39,10113F-HRTimeline
EntryPoint Capital, LLC53,015$432K0.17%-19,88413F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …50,144$408K<0.01%-4,32813F-HRTimelineGroup
Weiss Asset Management LPin group Weiss Asset Management LP50,001$407K0.01%013F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
OCCUDO QUANTITATIVE STRATEGIES LP47,674$388K0.05%-131,68013F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM47,362$386K<0.01%new13F-HRTimeline
SIMPLEX TRADING, LLC45,931$373K0.01%-30,71313F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND43,422$353K<0.01%013F-HRTimeline
Gotham Asset Management, LLC42,741$348K<0.01%+9,97513F-HRTimeline
LJI Wealth Management, LLC42,350$345K0.06%013F-HRTimeline
Police & Firemen's Retirement System of…41,362$337K<0.01%+9,70313F-HRTimeline
Savvy Advisors, Inc.40,465$329K0.02%013F-HRTimeline
Cetera Investment Advisers40,018$326K<0.01%-6,31413F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.40,351$325K<0.01%-2,35813F-HRTimelineGroup
TEACHER RETIREMENT SYSTEM OF TEXAS39,321$320K<0.01%new13F-HRTimeline
TUDOR INVESTMENT CORP ET AL37,994$309K<0.01%-187,19213F-HR/ATimeline
STATE BOARD OF ADMINISTRATION OF FLORID…37,970$309K<0.01%013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA36,285$295K<0.01%-8,06813F-HRTimelineGroup
Cambridge Investment Research Advisors,…34,642$282K<0.01%013F-HRTimeline
KLP KAPITALFORVALTNING AS33,400$272K<0.01%new13F-HRTimeline
LPL Financial LLC33,302$271K<0.01%-9,75013F-HRTimeline
Semanteon Capital Management, LP32,925$268K0.34%new13F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…32,652$266K<0.01%+29,35313F-HRTimeline
DIVERSIFIED TRUST CO32,062$261K0.01%-138,17313F-HRTimeline
ProShare Advisors LLC32,007$261K<0.01%-4,71613F-HRTimeline
WEALTH ENHANCEMENT ADVISORY SERVICES, L…31,107$258K<0.01%+4,34913F-HRTimeline
Cerity Partners LLCin group Cerity Partners LLC31,033$253K<0.01%+2,90513F-HRTimelineGroup
China Universal Asset Management Co., L…28,305$230K0.02%-3,86213F-HRTimeline
Baader Bank Aktiengesellschaft28,312$230K0.02%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
PROFUND ADVISORS LLC26,564$216K0.01%-15,51613F-HRTimeline
Asset Management Group, Inc.26,480$216K0.04%013F-HRTimeline
AXQ CAPITAL, LP26,356$215K0.08%new13F-HRTimeline
Janney Montgomery Scott LLC26,200$213K<0.01%+1,00013F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…25,744$210K0.06%+4,47013F-HRTimelineGroup
Skandinaviska Enskilda Banken AB (publ)25,000$204K<0.01%new13F-HRTimeline
OMERS ADMINISTRATION Corp24,600$200K<0.01%new13F-HRTimeline
Petrus Trust Company, LTA24,351$198K0.02%new13F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…23,196$189K<0.01%new13F-HRTimelineGroup
CIBC Bancorp USA Inc.group of 2 filers holding23,031$187K+16,367Timeline
Van Hulzen Asset Management, LLC22,182$181K0.01%+5,05813F-HRTimeline
Sunpointe, LLC21,000$171K0.06%013F-HRTimeline
Verdence Capital Advisors LLC17,549$163K0.01%new13F-HRTimeline
ASPIRIANT, LLC20,000$163K<0.01%new13F-HRTimeline
Tidal Investments LLCin group Tidal Investments LLC19,485$159K<0.01%new13F-HRTimelineGroup
Aigen Investment Management, LP19,129$156K0.02%new13F-HRTimeline
Numerai GP LLC18,507$151K0.02%new13F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC17,901$146K<0.01%-2,48113F-HRTimeline
Modern Wealth Management, LLC17,704$144K<0.01%013F-HRTimeline
Quantinno Capital Management LP17,694$144K<0.01%+5,12313F-HRTimeline
Rafferty Asset Management, LLC17,411$142K<0.01%-8,49213F-HRTimeline
Quadrature Capital Ltdin group Quadrature Capital Ltd17,289$141K<0.01%-29,46713F-HRTimelineGroup
VICTORY CAPITAL MANAGEMENT INC17,255$140K<0.01%-35313F-HRTimeline
Persistent Asset Partners Ltd17,202$140K0.1%new13F-HR/ATimeline
CAPSTONE INVESTMENT ADVISORS, LLCin group CAPSTONE INVESTMENT ADVISORS,…17,130$139K<0.01%new13F-HRTimelineGroup
Jacksonville Wealth Management, LLC17,000$138K0.1%new13F-HRTimeline
Arax Advisory Partners15,859$129K<0.01%new13F-HRTimeline
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.in group LANDSCAPE CAPITAL MANAGEMENT,…15,709$128K0.01%013F-HRTimelineGroup
PRELUDE CAPITAL MANAGEMENT, LLC15,500$126K0.01%013F-HRTimeline
Atom Investors LP14,968$122K0.01%-3,18713F-HRTimeline
Veery Capital, LLC14,163$115K0.04%013F-HRTimeline
Empirical Financial Services, LLC d.b.a…13,650$111K<0.01%013F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …13,155$107K<0.01%new13F-HRTimelineGroup
State of Wyoming12,900$105K0.01%-22,30613F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…12,827$104K<0.01%-1,37813F-HRTimelineGroup
R Squared Ltd12,709$103K0.04%new13F-HRTimeline
Verition Fund Management LLC12,229$99.5K<0.01%new13F-HRTimeline
XPONANCE LLC11,985$97.6K<0.01%+52513F-HRTimeline
CAPTRUST FINANCIAL ADVISORS11,904$96.9K<0.01%+1,09813F-HRTimeline
Apella Capital, LLC10,000$91.4K<0.01%013F-HRTimeline
Pallas Capital Advisors LLC11,027$89.8K<0.01%+2213F-HRTimeline
MERCER GLOBAL ADVISORS INC /ADV10,466$85.2K<0.01%new13F-HRTimeline
Mariner, LLCin group Mariner, LLC10,404$84.7K<0.01%-1,33313F-HRTimelineGroup
O'SHAUGHNESSY ASSET MANAGEMENT, LLC10,160$82.7K<0.01%new13F-HRTimeline
State of Alaska, Department of Revenue8,457$68K<0.01%new13F-HRTimeline
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…7,789$63.4K<0.01%+5,00013F-HRTimelineGroup
GROUP ONE TRADING LLC6,024$49K<0.01%new13F-HRTimeline
AMALGAMATED BANK4,834$39K<0.01%013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…4,454$36.3K<0.01%-12,94113F-HRTimelineGroup
AlphaQuest LLC4,300$35K<0.01%new13F-HRTimeline
Truvestments Capital LLC4,139$33.7K0.01%+56613F-HRTimeline
WEBSTER BANK, N. A.4,000$32.6K<0.01%+1,00013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.3,474$28.3K<0.01%-34313F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP2,781$22.7K<0.01%+1,30313F-HRTimelineGroup
Farther Finance Advisors, LLC2,381$19.4K<0.01%+2,20013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC2,204$17.9K<0.01%013F-HRTimeline
CREATIVE FINANCIAL DESIGNS INC /ADV2,200$17.9K<0.01%+30013F-HRTimeline
SBI Securities Co., Ltd.1,913$15.6K<0.01%+613F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…1,877$15.3K<0.01%-31413F-HRTimelineGroup
Allworth Financial LP1,765$14.4K<0.01%-31113F-HRTimeline
Fortitude Family Office, LLC1,553$12.6K<0.01%013F-HRTimeline
Essential Partners LLC1,427$11.6K<0.01%+36213F-HRTimeline
TSFG, LLC1,058$9K<0.01%013F-HRTimeline
True Wealth Design, LLC1,011$8.23K<0.01%+4413F-HRTimeline