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Disclosery

VRTX VERTEX PHARMACEUTICALS INC

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COM (common), issuer CIK 875320

1,632 managers (1,675 13F filers) reported a position in VRTX shares at 2025-12-31, 241,593,776 shares in all. 163 filers opened a position and 101 filers sold out during the quarter.

Managers
1,632
13F filers
1,675
New
163
Added
620
Reduced
566
Sold out
101
Shares held by filers
241,593,776

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
KEYNOTE FINANCIAL SERVICES LLC1,166$529K0.3%+1213F-HRTimeline
DGS Capital Management, LLCin group DGS Capital Management, LLC1,161$526K0.09%+30713F-HRTimelineGroup
WRAPMANAGER INC1,156$524K0.18%-2313F-HRTimeline
Redhawk Wealth Advisors, Inc.1,156$524K0.06%+4613F-HRTimeline
Williams Jones Wealth Management, LLC.1,155$524K0.01%+2113F-HRTimeline
Venture Visionary Partners LLC1,154$523K0.02%+19713F-HRTimeline
TOBAM1,154$523K0.13%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
Meadowbrook Advisors Group, LLC1,151$522K0.29%13F-HRTimeline
Resurgent Financial Advisors LLC1,149$521K0.26%new13F-HRTimeline
Second Line Capital, LLC1,144$519K0.11%+2913F-HRTimeline
SmartHarvest Portfolios, LLC1,142$518K0.18%13F-HRTimeline
Legato Capital Management LLC1,141$517K0.04%new13F-HRTimeline
LCM Capital Management Inc1,135$515K0.25%-1013F-HRTimeline
DAVIS R M INC1,135$514K0.01%+36013F-HRTimeline
First Commonwealth Financial Corp /PA/in group First Commonwealth Financial …1,134$514K0.08%-113F-HRTimelineGroup
WESTFIELD CAPITAL MANAGEMENT CO LP1,132$513K<0.01%new13F-HRTimeline
WBI INVESTMENTS, LLCin group WBI INVESTMENTS, LLC1,114$505K0.13%new13F-HRTimelineGroup
REGIONS FINANCIAL CORPin group REGIONS FINANCIAL CORP1,109$503K<0.01%+46213F-HRTimelineGroup
MONETA GROUP INVESTMENT ADVISORS LLC1,107$502K<0.01%-7013F-HRTimeline
Sage Capital Advisors,llc1,104$500K0.12%+5313F-HRTimeline
Founders Financial Alliance, LLC1,101$499K0.09%+5613F-HRTimeline
Fairfield Financial Advisors, LTD1,098$498K0.16%+35513F-HRTimeline
Bridgewater Advisors Inc.1,076$496K0.03%+713F-HRTimeline
HARBOR INVESTMENT ADVISORY, LLC1,094$496K0.04%-5913F-HRTimeline
Kenora Financial, LLC1,091$495K0.17%013F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…1,091$494K0.02%+15913F-HRTimelineGroup
Larson Financial Group LLC1,087$493K0.02%+22413F-HRTimeline
NorthRock Partners, LLC1,085$492K0.01%-2,36713F-HRTimeline
NorthCrest Asset Manangement, LLC1,095$492K0.01%-27113F-HRTimeline
OPTIMIZE FINANCIAL INC.1,084$491K0.25%+1213F-HRTimeline
Cynosure Group, LLC1,079$489K0.05%+16113F-HRTimeline
ALBION FINANCIAL GROUP /UT1,077$488K0.03%-3213F-HRTimeline
INDEPENDENT FINANCIAL GROUP, LLC1,069$485K0.01%-12213F-HRTimeline
EntryPoint Capital, LLC1,066$483K0.19%new13F-HRTimeline
Jacobi Capital Management LLC1,061$481K0.03%+1913F-HRTimeline
GUARDIAN WEALTH ADVISORS, LLC / NC1,053$477K0.03%+213F-HRTimeline
Ramiah Investment Group1,044$473K0.41%+7413F-HRTimeline
INVESTMENT MANAGEMENT CORP /VA/ /ADV1,043$473K0.4%+1613F-HRTimeline
Optas, LLC1,035$469K0.07%+27113F-HRTimeline
Parsonex Advisory Services, Inc.1,031$467K0.3%+1313F-HRTimeline
FLOW TRADERS U.S. LLC1,029$467K0.02%new13F-HRTimeline
Sunbelt Securities, Inc.1,026$465K0.03%-1213F-HRTimeline
Dynasty Wealth Management, LLC1,013$459K<0.01%new13F-HRTimeline
GeoWealth Management, LLC1,010$458K0.02%-813F-HRTimeline
TOWNSQUARE CAPITAL LLC1,007$457K0.1%+15213F-HRTimeline
AGH Wealth Advisors, LLC1,006$456K0.34%+7113F-HRTimeline
KLINGENSTEIN FIELDS & CO LP1,005$456K0.02%013F-HRTimeline
Parkside Financial Bank & Trust1,002$454K0.03%+30813F-HRTimeline
SCHWARTZ INVESTMENT COUNSEL INC1,000$453K0.02%013F-HRTimeline
WASHINGTON GROWTH STRATEGIES LLC998$452K0.29%013F-HRTimeline
Alta Advisers Ltdin group Alta Advisers Ltd991$449K0.16%-28013F-HRTimelineGroup
Curi Capital, LLC991$449K0.01%-7913F-HRTimeline
17 CAPITAL PARTNERS, LLC990$449K0.23%013F-HRTimeline
Clarius Group, LLC983$446K0.03%-413F-HRTimeline
KCM INVESTMENT ADVISORS LLC976$442K0.01%new13F-HRTimeline
DEFINED WEALTH MANAGEMENT, LLC974$442K0.25%+4213F-HRTimeline
SK Wealth Management, LLC927$441K0.12%013F-HRTimeline
Advyzon Investment Management, LLC966$438K0.05%new13F-HRTimeline
Strategic Family Wealth Counselors, L.L…987$436K0.1%new13F-HRTimeline
RICHARDSON FINANCIAL SERVICES INC.952$432K0.14%+1013F-HRTimeline
Ausdal Financial Partners, Inc.938$425K0.02%-57513F-HRTimeline
CONGRESS ASSET MANAGEMENT CO937$425K<0.01%-159,93813F-HRTimeline
CABOT WEALTH MANAGEMENT INC930$422K0.05%-64513F-HRTimeline
Fulton Bank, N.A.927$420K0.01%-9713F-HRTimeline
Elevated Private Wealth, LLC916$415K0.43%13F-HRTimeline
Quotient Wealth Partners, LLC914$414K0.01%-1213F-HRTimeline
FIRST CITIZENS BANK & TRUST CO910$413K0.01%-73013F-HRTimeline
Vantus Wealth LLC908$412K0.3%13F-HRTimeline
GREAT VALLEY ADVISOR GROUP, INC.in group GREAT VALLEY ADVISOR GROUP, I…907$411K0.01%-11813F-HRTimelineGroup
Granite Bay Wealth Management, LLC902$409K0.1%+213F-HRTimeline
Fullerton Fund Management Co Ltd.900$408K0.02%-62213F-HRTimeline
Ancora Advisors LLCin group Ancora Advisors LLC899$408K0.01%+6213F-HRTimelineGroup
RiverFront Investment Group, LLC899$408K0.01%-913F-HRTimeline
Chicago Partners Investment Group LLC867$406K0.01%-14013F-HRTimeline
E Fund Management (Hong Kong) Co., Ltd.860$406K0.14%+61613F-HRTimeline
Aigen Investment Management, LP894$405K0.09%new13F-HRTimeline
WILLNER & HELLER, LLC893$405K0.29%-18213F-HRTimeline
Guardian Asset Advisors, LLC885$401K0.21%+1013F-HRTimeline
Ellevest, Inc.881$399K0.06%-1813F-HRTimeline
Forza Wealth Management, LLC881$399K0.14%013F-HRTimeline
HBK Sorce Advisory LLC835$399K0.01%+17113F-HRTimeline
Independence Bank of Kentucky876$397K0.05%+4013F-HRTimeline
Soltis Investment Advisors LLC874$396K0.03%+11613F-HR/ATimeline
DELTA FINANCIAL ADVISORS LLC872$395K0.1%+5613F-HRTimeline
Prescott Group Capital Management, L.L.…869$394K0.04%013F-HRTimeline
George Kaiser Family Foundation869$394K0.05%013F-HRTimeline
Marble Wealth, LLC865$392K0.05%13F-HRTimeline
Prestige Wealth Management Group LLC858$389K0.07%+78113F-HRTimeline
Freestone Capital Holdings, LLCin group Freestone Capital Holdings, L…849$385K0.01%-6313F-HRTimelineGroup
Moss Adams Wealth Advisors LLC848$385K0.03%+22013F-HRTimeline
Foundations Investment Advisors, LLC847$384K0.01%-1713F-HRTimeline
AA Financial Advisors, LLC846$384K0.07%+8513F-HRTimeline
Douglass Winthrop Advisors, LLC841$381K0.01%-6813F-HRTimeline
YHB Investment Advisors, Inc.841$381K0.03%-5213F-HRTimeline
Purpose Unlimited Inc.in group Purpose Unlimited Inc.835$379K0.02%13F-HRTimelineGroup
Trust Co of the South834$378K0.06%new13F-HRTimeline
Gallacher Capital Management LLC827$375K0.14%-813F-HRTimeline
RFG Advisory, LLC827$375K0.01%new13F-HRTimeline
New Republic Capital, LLC825$374K0.1%new13F-HRTimeline
FSM Wealth Advisors, LLC823$373K0.05%new13F-HRTimeline
PUREfi Wealth, LLC817$370K0.28%-12613F-HRTimeline
BLUEDOOR PRIVATE WEALTH, LLC817$370K0.17%13F-HRTimeline
D.B. Root & Company, LLC813$369K0.09%-14413F-HRTimeline
Meridian Wealth Management, LLC810$367K0.01%+10113F-HRTimeline
Sovran Advisors, LLC833$366K0.03%-49513F-HRTimeline
Balefire, LLC802$364K0.07%new13F-HRTimeline
Arlington Capital Management, Inc.800$363K0.22%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
EVERPAR ADVISORS LLC798$362K0.13%+4513F-HRTimeline
MONTAG A & ASSOCIATES INC797$361K0.02%+58713F-HRTimeline
INTEGRITY ALLIANCE, LLC.790$358K0.01%new13F-HRTimeline
ARTHUR M. COHEN & ASSOCIATES, LLC790$358K0.06%-10013F-HRTimeline
Basecamp Wealth Advisors LLC789$358K0.08%13F-HRTimeline
Chesley Taft & Associates LLC782$355K0.01%+21913F-HRTimeline
Pinnacle Wealth Management Advisory Gro…780$354K0.02%+1513F-HRTimeline
Cercano Management LLC780$354K0.01%013F-HRTimeline
Newman Dignan & Sheerar, Inc.779$353K0.07%-3713F-HRTimeline
SEVEN MILE ADVISORY778$353K0.06%-413F-HRTimeline
ATALANTA SOSNOFF CAPITAL, LLCin group ATALANTA SOSNOFF CAPITAL, LLC773$350K0.01%+213F-HRTimelineGroup
One Charles Private Wealth Services, LLC767$348K0.09%-6013F-HRTimeline
denkapparat Operations GmbH766$347K0.19%013F-HRTimeline
Income Insurance Ltd764$346K0.22%13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
SUMMIT SECURITIES GROUP LLC763$346K0.06%+67913F-HRTimeline
AlTi Global, Inc.in group AlTi Global, Inc.762$345K0.01%new13F-HRTimelineGroup
AlphaGrep UK Ltd760$345K0.12%13F-HRTimeline
CURA WEALTH ADVISORS, LLC760$344K0.13%+2613F-HRTimeline
Financial Symmetry Inc755$342K0.14%013F-HRTimeline
Baker Chad R750$340K0.06%-8,99013F-HRTimeline
NORTHSTAR ASSET MANAGEMENT Co750$340K0.07%013F-HRTimeline
FourThought Financial Partners, LLC748$339K0.03%+1813F-HRTimeline
BOSTON FAMILY OFFICE LLC746$338K0.02%013F-HRTimeline
Haverford Trust Co740$335K<0.01%new13F-HRTimeline
DRW Securities, LLC746$335K0.03%new13F-HRTimeline
WASHINGTON TRUST Co734$333K0.01%+613F-HRTimeline
CYBER HORNET ETFs LLC734$333K0.2%+3913F-HRTimeline
Nicholas Hoffman & Company, LLC.732$332K0.01%013F-HRTimeline
GK Wealth Management LLC732$332K0.24%-3513F-HRTimeline
CHILDRESS CAPITAL ADVISORS, LLC730$331K0.05%+2213F-HRTimeline
CASTLEARK MANAGEMENT LLC730$331K0.01%013F-HRTimeline
Turtle Creek Wealth Advisors, LLC723$328K0.03%+7013F-HRTimeline
Massachusetts Wealth Management722$327K0.15%013F-HRTimeline
WEDGEWOOD INVESTORS INC /PA/720$326K0.37%new13F-HRTimeline
Eagle Wealth Advisors LLC716$325K0.28%13F-HRTimeline
Physician Wealth Advisors, Inc.712$323K0.04%+1413F-HRTimeline
Nautilus Advisors LLC710$322K0.21%+5013F-HRTimeline
Quantbot Technologies LP709$321K0.01%-3,01813F-HRTimeline
Alpha Zero LLC708$321K0.18%-2713F-HRTimeline
DARK FOREST CAPITAL MANAGEMENT LP706$320K0.01%-1,30413F-HRTimeline
DAYMARK WEALTH PARTNERS, LLC697$316K0.01%-213F-HRTimeline
Versant Capital Management, Inc696$316K0.04%+47813F-HRTimeline
Ignite Planners, LLC667$313K0.05%new13F-HRTimeline
STOCK YARDS BANK & TRUST CO691$313K0.01%-9813F-HRTimeline
EFG International AGin group EFG International AG687$311K0.01%13F-HRTimelineGroup
William Mack & Associates, Inc.682$309K0.15%013F-HRTimeline
Sivia Capital Partners, LLC678$307K0.06%-213F-HRTimeline
Alvarez & Marsal Private Wealth Partner…678$307K0.06%13F-HRTimeline
Center For Asset Management LLC677$307K0.16%new13F-HRTimeline
TRUE Private Wealth Advisors676$306K0.03%-16413F-HRTimeline
May Hill Capital, LLC666$302K0.08%+2613F-HR/ATimeline
Mason & Associates Inc665$301K0.06%+1013F-HRTimeline
ICW Investment Advisors LLC664$301K0.11%+3213F-HRTimeline
Cromwell Holdings LLC663$301K0.16%013F-HRTimeline
Abundance Wealth Counselors663$301K0.05%+113F-HRTimeline
AlphaQuest LLC661$300K0.02%-35513F-HRTimeline
DIVERSIFIED TRUST CO661$300K0.01%+5013F-HRTimeline
Koss-Olinger Consulting, LLC659$299K0.02%-29813F-HRTimeline
Zullo Investment Group, Inc.659$299K0.11%-2013F-HRTimeline
Financial Engines Advisors L.L.C.653$296K<0.01%+2513F-HRTimeline
EARNED WEALTH ADVISORS, LLC650$295K0.02%+2113F-HR/ATimeline
SITTNER & NELSON, LLC615$294K0.1%013F-HRTimeline
Clarity Financial LLC645$292K0.03%013F-HRTimeline
One Capital Management, LLC641$291K0.01%-1513F-HRTimeline
SENTRY INVESTMENT MANAGEMENT LLC640$290K0.19%013F-HRTimeline
GRIMES & Co WEALTH MANAGEMENT, LLC636$288K0.01%+1513F-HRTimeline
Spectrum Asset Management, Inc. (NB/CA)634$287K0.1%new13F-HRTimeline
Wilmington Savings Fund Society, FSB629$285K0.01%013F-HRTimeline
CIM, LLC629$285K0.04%-213F-HRTimeline
Western Wealth Management, LLC628$285K0.01%+5213F-HRTimeline
FAIRFIELD, BUSH & CO.626$284K0.15%-4513F-HRTimeline
Urban Wealth Management, LLC626$284K0.26%13F-HRTimeline
Green Alpha Advisors, LLC625$283K0.26%new13F-HRTimeline
Park Place Capital Corp625$283K0.06%+7013F-HRTimeline
Financiere des Professionnels - Fonds d…625$283K0.02%new13F-HRTimeline
Fox Hill Wealth Management625$283K0.13%-2413F-HRTimeline
Interchange Capital Partners, LLC620$281K0.05%-16413F-HRTimeline
FIRST AMERICAN BANK614$278K0.02%013F-HRTimeline
KPP Advisory Services LLC613$278K0.04%-1313F-HRTimeline
Keudell/Morrison Wealth Management612$277K0.06%13F-HRTimeline
Tannin Capital LLC609$276K0.25%13F-HRTimeline
KRAEMATON INVESTMENT ADVISORS, INC608$275K0.22%-14013F-HRTimeline
Aries Wealth Management605$274K0.06%013F-HRTimeline
Centurion Wealth Management LLC603$273K0.06%+1813F-HRTimeline
Costello Asset Management, INC601$272K0.09%+1213F-HRTimeline
BARTLETT & CO. WEALTH MANAGEMENT LLC601$272K<0.01%+113F-HRTimeline
Strategic Blueprint, LLC600$272K0.02%-1,16413F-HRTimeline
Coastline Trust Co597$271K0.03%013F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
Midwest Trust Co596$270K<0.01%-2413F-HRTimeline
Trek Financial, LLC593$269K0.02%+3713F-HRTimeline
TBH Global Asset Management, LLC592$269K0.04%new13F-HRTimeline
Aprio Wealth Management, LLC592$268K0.02%new13F-HRTimeline
PURSUE WEALTH PARTNERS LLC591$268K0.13%013F-HRTimeline