RA CAPITAL MANAGEMENT, L.P. in group RA CAPITAL MANAGEMENT, L.P. More: the full row for RA CAPITAL MANAGEMENT, L.P. 1,982,301 $96.6M 1.19% new 13F-HR Timeline Group Venrock Adviser, LLC More: the full row for Venrock Adviser, LLC 499,966 $24.4M 1.37% new 13F-HR Timeline FCPM III SERVICES B.V. in group FCPM III SERVICES B.V. More: the full row for FCPM III SERVICES B.V. 379,640 $18.5M 3.7% new 13F-HR Timeline Group FMR LLC in group FMR LLC More: the full row for FMR LLC 236,508 $11.5M <0.01% new 13F-HR Timeline Group Ariose Capital Management Ltd More: the full row for Ariose Capital Management Ltd 110,173 $5.37M 1.8% new 13F-HR Timeline VANGUARD GROUP INC in group VANGUARD GROUP INC More: the full row for VANGUARD GROUP INC 105,190 $5.12M <0.01% new 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 75,909 $3.7M <0.01% new 13F-HR Timeline Group TANG CAPITAL MANAGEMENT LLC in group TANG CAPITAL MANAGEMENT LLC More: the full row for TANG CAPITAL MANAGEMENT LLC 50,000 $2.44M 0.09% new 13F-HR Timeline Group BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 34,530 $1.68M <0.01% new 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 27,392 $1.33M <0.01% new 13F-HR Timeline Group Woodline Partners LP More: the full row for Woodline Partners LP 27,363 $1.33M 0.01% new 13F-HR Timeline Sarissa Capital Management LP More: the full row for Sarissa Capital Management LP 25,399 $1.24M 0.69% new 13F-HR Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 24,764 $1.21M <0.01% new 13F-HR Timeline Group Polymer Capital Management (HK) LTD More: the full row for Polymer Capital Management (HK) LTD 21,248 $1.04M 0.14% new 13F-HR Timeline JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 16,753 $816K <0.01% new 13F-HR Timeline Group GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 15,786 $769K <0.01% new 13F-HR Timeline Group RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 14,600 $711K <0.01% new 13F-HR Timeline STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 9,054 $441K <0.01% new 13F-HR Timeline Group Virtu Financial LLC in group Virtu Financial LLC More: the full row for Virtu Financial LLC 8,104 $395K 0.02% new 13F-HR Timeline Group BRIDGEWAY CAPITAL MANAGEMENT, LLC More: the full row for BRIDGEWAY CAPITAL MANAGEMENT, LLC 6,250 $304K 0.01% new 13F-HR Timeline Scientech Research LLC More: the full row for Scientech Research LLC 6,097 $297K 0.1% new 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 6,075 $296K <0.01% new 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 5,686 $277K <0.01% new 13F-HR Timeline Group BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 4,754 $232K <0.01% new 13F-HR/A Timeline Group Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 4,729 $230K <0.01% new 13F-HR Timeline Group Trustees of Columbia University in the … More: the full row for Trustees of Columbia University in the City of New York 4,595 $224K 0.03% new 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 4,456 $217K <0.01% new 13F-HR/A Timeline Group Bollard Group LLC More: the full row for Bollard Group LLC 2,777 $135K <0.01% new 13F-HR Timeline Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 110 $5.36K <0.01% new 13F-HR Timeline JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 78 $3.8K <0.01% new 13F-HR/A Timeline Group MAI Capital Management More: the full row for MAI Capital Management 40 $1.95K <0.01% new 13F-HR Timeline Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 4 $195 <0.01% new 13F-HR Timeline Group Allworth Financial LP More: the full row for Allworth Financial LP 3 $147 <0.01% new 13F-HR Timeline SBI Securities Co., Ltd. More: the full row for SBI Securities Co., Ltd. 3 $146 <0.01% new 13F-HR Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 1 $49 <0.01% new 13F-HR Timeline Group ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 2 $0 0% new 13F-HR Timeline Group Value filed as zero, left out of ratios.