Essex Woodlands Management, Inc. More: the full row for Essex Woodlands Management, Inc. 4,110,709 $5.02M 1.45% 0 13F-HR Timeline Nantahala Capital Management, LLC in group Nantahala Capital Management,… More: the full row for Nantahala Capital Management, LLC 3,877,965 $4.73M 0.39% +198,239 13F-HR Timeline Group SILVERARC CAPITAL MANAGEMENT, LLC in group SILVERARC CAPITAL MANAGEMENT,… More: the full row for SILVERARC CAPITAL MANAGEMENT, LLC 2,771,288 $3.38M 0.71% -294,361 13F-HR Timeline Group Stonepine Capital Management, LLC More: the full row for Stonepine Capital Management, LLC 2,055,225 $2.51M 2.44% -297,874 13F-HR Timeline VANGUARD GROUP INC in group VANGUARD GROUP INC More: the full row for VANGUARD GROUP INC 1,928,173 $2.35M <0.01% +52,594 13F-HR Timeline Group DAFNA Capital Management LLC More: the full row for DAFNA Capital Management LLC 1,441,029 $1.76M 0.5% 0 13F-HR Timeline AIGH Capital Management LLC More: the full row for AIGH Capital Management LLC 1,416,323 $1.73M 0.9% -1,246,462 13F-HR Timeline Pentwater Capital Management LP More: the full row for Pentwater Capital Management LP 998,755 $1.22M 0.02% -1,245 13F-HR Timeline PERKINS CAPITAL MANAGEMENT INC More: the full row for PERKINS CAPITAL MANAGEMENT INC 910,615 $1.11M 1.17% +2,750 13F-HR Timeline CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 750,000 $915K <0.01% 0 13F-HR Timeline Group Velan Capital Investment Management LP More: the full row for Velan Capital Investment Management LP 747,410 $912K 0.94% new 13F-HR Timeline Sio Capital Management, LLC More: the full row for Sio Capital Management, LLC 630,000 $769K 0.23% 0 13F-HR Timeline BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 425,866 $520K <0.01% -1,662 13F-HR Timeline Group Mink Brook Asset Management LLC in group Mink Brook Asset Management L… More: the full row for Mink Brook Asset Management LLC 357,092 $436K 0.46% 0 13F-HR Timeline Group GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 346,668 $423K <0.01% +35,263 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 330,683 $403K <0.01% -437,147 13F-HR Timeline Group RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 244,444 $298K <0.01% -180,696 13F-HR Timeline PARADIGM CAPITAL MANAGEMENT INC/NY More: the full row for PARADIGM CAPITAL MANAGEMENT INC/NY 200,000 $244K 0.01% new 13F-HR Timeline Birchview Capital, LP More: the full row for Birchview Capital, LP 155,000 $189K 0.16% +30,000 13F-HR Timeline JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 108,367 $132K <0.01% -25,299 13F-HR Timeline Group UP STRATEGIC WEALTH INVESTMENT ADVISORS… More: the full row for UP STRATEGIC WEALTH INVESTMENT ADVISORS LLC 99,888 $122K 0.11% 0 13F-HR Timeline SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 90,515 $110K <0.01% new 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 66,006 $80.5K <0.01% +9,496 13F-HR Timeline Group NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 64,799 $79.1K <0.01% +17,618 13F-HR Timeline Group STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 63,383 $77.3K <0.01% -2,100 13F-HR Timeline Group BRIDGEWAY CAPITAL MANAGEMENT, LLC More: the full row for BRIDGEWAY CAPITAL MANAGEMENT, LLC 57,500 $70.2K <0.01% +6,800 13F-HR Timeline PNC Financial Services Group, Inc. in group PNC Financial Services Group,… More: the full row for PNC Financial Services Group, Inc. 53,612 $65.4K <0.01% 0 13F-HR Timeline Group Atom Investors LP More: the full row for Atom Investors LP 48,110 $58.7K 0.01% new 13F-HR Timeline GSA CAPITAL PARTNERS LLP More: the full row for GSA CAPITAL PARTNERS LLP 40,664 $50K <0.01% -95,090 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 39,120 $47.7K <0.01% +21,298 13F-HR Timeline Group COMMONWEALTH EQUITY SERVICES, LLC More: the full row for COMMONWEALTH EQUITY SERVICES, LLC 28,441 $35K <0.01% 0 13F-HR Timeline OCCUDO QUANTITATIVE STRATEGIES LP More: the full row for OCCUDO QUANTITATIVE STRATEGIES LP 19,960 $24.7K <0.01% 0 13F-HR Timeline Rollins Financial Advisors, LLC More: the full row for Rollins Financial Advisors, LLC 18,656 $22.8K <0.01% new 13F-HR/A Timeline Walleye Capital LLC in group Walleye Capital LLC More: the full row for Walleye Capital LLC 15,301 $18.7K <0.01% -14,837 13F-HR Timeline Group Embree Financial Group More: the full row for Embree Financial Group 14,000 $17.1K <0.01% +1,500 13F-HR Timeline SG Americas Securities, LLC More: the full row for SG Americas Securities, LLC 12,769 $16K <0.01% new 13F-HR Timeline PRUDENTIAL FINANCIAL INC in group PRUDENTIAL FINANCIAL INC More: the full row for PRUDENTIAL FINANCIAL INC 12,200 $14.9K <0.01% -6,600 13F-HR Timeline Group JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 11,219 $13.7K <0.01% -19,486 13F-HR/A Timeline Group HighTower Advisors, LLC More: the full row for HighTower Advisors, LLC 10,352 $12.6K <0.01% new 13F-HR Timeline XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 10,156 $12.4K <0.01% new 13F-HR Timeline Group COLDSTREAM CAPITAL MANAGEMENT INC More: the full row for COLDSTREAM CAPITAL MANAGEMENT INC 3,667 $4.47K <0.01% new 13F-HR Timeline Steward Partners Investment Advisory, L… More: the full row for Steward Partners Investment Advisory, LLC 1,991 $2.43K <0.01% new 13F-HR Timeline FEDERATED HERMES, INC. in group FEDERATED HERMES, INC. More: the full row for FEDERATED HERMES, INC. 563 $687 <0.01% new 13F-HR Timeline Group SBI Securities Co., Ltd. More: the full row for SBI Securities Co., Ltd. 371 $453 <0.01% -330 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 252 $307 <0.01% +12 13F-HR Timeline Group BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 224 $273 <0.01% -90 13F-HR Timeline Group OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 100 $122 <0.01% new 13F-HR Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 4 $5 <0.01% new 13F-HR/A Timeline Group CWM, LLC in group CWM, LLC More: the full row for CWM, LLC 337 $0 0% 0 13F-HR Timeline Group Value filed as zero, left out of ratios. SIMPLEX TRADING, LLC More: the full row for SIMPLEX TRADING, LLC 310 $0 0% new 13F-HR Timeline Value filed as zero, left out of ratios. CONCOURSE FINANCIAL GROUP SECURITIES, I… More: the full row for CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0 $0 0 13F-HR Timeline Value filed as zero, left out of ratios. Amount filed as zero, left out of ratios.