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Disclosery

PRME PRIME MEDICINE INC

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COM (common), issuer CIK 1894562

120 managers (122 13F filers) reported a position in PRME shares at 2025-06-30, 58,686,348 shares in all. 28 filers opened a position and 33 filers sold out during the quarter.

Managers
120
13F filers
122
New
28
Added
36
Reduced
35
Sold out
33
Shares held by filers
58,686,348

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2025

Filers in the available 13F reports with a share position at 2025-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Alphabet Inc.in group Alphabet Inc.15,062,498$37.2M1.74%013F-HRTimelineGroup
T. Rowe Price Investment Management, In…6,484,787$16M0.01%+2,341,69113F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.4,485,828$11.1M<0.01%+179,61713F-HRTimelineGroup
FMR LLCin group FMR LLC3,744,427$9.25M<0.01%-2,80813F-HRTimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding3,650,701$9.02M-5,884Timeline
ARK Investment Management LLCin group ARK Investment Management LLC2,322,669$5.74M0.04%-772,50313F-HRTimelineGroup
Redmile Group, LLCin group Redmile Group, LLC2,074,350$5.12M0.55%013F-HRTimelineGroup
MWG Management Ltd.1,792,210$4.43M8.53%013F-HRTimeline
Sumitomo Mitsui Trust Group, Inc.in group Sumitomo Mitsui Trust Group, …1,594,518$3.94M<0.01%-1,331,50513F-HRTimelineGroup
Amova Asset Management Americas, Inc.in group Amova Asset Management Americ…1,589,117$3.89M0.04%-1,336,90613F-HRTimelineGroup
Casdin Capital, LLC1,567,175$3.87M0.35%+1,200,00013F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,510,749$3.73M<0.01%-15,78113F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP1,239,337$3.06M<0.01%+94,03213F-HRTimelineGroup
Greenwich Wealth Management LLC846,201$2.09M0.1%+27,20013F-HRTimeline
Schonfeld Strategic Advisors LLC818,518$2.02M0.02%new13F-HRTimeline
FARALLON CAPITAL MANAGEMENT, L.L.C.750,000$1.85M0.01%013F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
MORGAN STANLEYin group MORGAN STANLEY587,676$1.45M<0.01%+232,50013F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC521,508$1.29M<0.01%new13F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co518,628$1.28M<0.01%+14,93113F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP512,234$1.27M<0.01%-15,07513F-HRTimelineGroup
MOORE CAPITAL MANAGEMENT, LP500,000$1.24M0.02%013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…482,728$1.19M<0.01%+340,10913F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC424,355$1.05M<0.01%+180,56013F-HRTimelineGroup
FRED ALGER MANAGEMENT, LLCin group FRED ALGER MANAGEMENT, LLC383,194$946K<0.01%new13F-HRTimelineGroup
Bollard Group LLC361,136$892K0.02%013F-HRTimeline
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding258,423$638K-54,247Timeline
RENAISSANCE TECHNOLOGIES LLC223,400$552K<0.01%-224,20013F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC214,800$531K0.01%new13F-HRTimeline
CHELSEA COUNSEL CO208,210$514K0.26%013F-HRTimeline
Nuveen, LLCin group TIAA207,894$513K<0.01%+148,49213F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC207,008$511K<0.01%-44,39113F-HRTimelineGroup
UBS Group AGin group UBS Group AG195,327$482K<0.01%+77,64713F-HRTimelineGroup
SIMPLEX TRADING, LLC193,615$478K0.01%+185,23913F-HRTimeline
Palumbo Wealth Management LLC183,358$453K0.14%+87,89613F-HRTimeline
ALLIANCEBERNSTEIN L.P.167,420$414K<0.01%+91,42013F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp162,052$400K<0.01%+6,06013F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC147,996$366K<0.01%-1,631,94913F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/144,511$357K<0.01%+31,58513F-HRTimelineGroup
LEVIN CAPITAL STRATEGIES, L.P.140,000$346K0.03%+105,00013F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd133,490$330K0.01%new13F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\125,445$310K<0.01%-1,40113F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding124,928$309K+86,621Timeline
FIL Ltdin group FIL Ltd117,270$290K<0.01%-3,74713F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC114,802$284K<0.01%+43,37813F-HR/ATimelineGroup
Diametric Capital, LP105,530$261K0.14%new13F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN101,151$250K<0.01%+10,33213F-HRTimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/98,807$244K<0.01%new13F-HR/ATimelineGroup
RHUMBLINE ADVISERS97,972$242K<0.01%+16,07213F-HRTimeline
Green Alpha Advisors, LLC78,994$195K0.19%-4,47313F-HRTimeline
Mutual Advisors, LLC45,200$190K<0.01%new13F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/65,320$162K<0.01%-1,501,87213F-HRTimeline
HRT FINANCIAL LP64,167$158K<0.01%new13F-HRTimeline
PRELUDE CAPITAL MANAGEMENT, LLC41,288$102K0.01%new13F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…39,014$96.4K<0.01%new13F-HRTimelineGroup
Jaffetilchin Investment Partners, LLC37,744$93.2K0.01%new13F-HRTimeline
AXQ CAPITAL, LP37,587$92.8K0.03%new13F-HRTimeline
IEQ CAPITAL, LLC35,830$88.5K<0.01%+94813F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC35,826$88.5K<0.01%new13F-HR/ATimelineGroup
CWM, LLCin group CWM, LLC35,761$88K<0.01%+15,29513F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC34,759$85.9K<0.01%-7,54313F-HRTimelineGroup
IQ EQ FUND MANAGEMENT (IRELAND) Ltd33,660$83.1K0.01%-56,21013F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO33,035$81.6K<0.01%-2,62813F-HRTimelineGroup
WEALTH ENHANCEMENT ADVISORY SERVICES, L…26,007$80.9K<0.01%+13,77713F-HRTimeline
Crestwood Advisors Group, LLC31,687$78.3K<0.01%013F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC30,810$76.1K<0.01%-24,13613F-HRTimeline
SG Americas Securities, LLC27,919$69K<0.01%-23,53713F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC27,145$67K<0.01%new13F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS26,735$66K<0.01%-4,58713F-HRTimelineGroup
China Universal Asset Management Co., L…26,370$65.1K0.01%+6113F-HRTimeline
Kingsview Wealth Management, LLC25,000$61.8K<0.01%new13F-HRTimeline
TD Asset Management Inc22,910$56.6K<0.01%-23,52413F-HRTimeline
HighTower Advisors, LLC21,354$52.7K<0.01%-29213F-HRTimeline
Federation des caisses Desjardins du Qu…21,200$52.4K<0.01%new13F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …20,979$51.8K<0.01%-3,94513F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC17,222$42.5K<0.01%013F-HRTimelineGroup
Police & Firemen's Retirement System of…17,092$42.2K<0.01%013F-HRTimeline
ProShare Advisors LLC16,871$41.7K<0.01%-1,32313F-HRTimeline
Clarius Group, LLC16,080$39.7K<0.01%013F-HRTimeline
Prime Capital Investment Advisors, LLC16,031$39.6K<0.01%-8,23013F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC14,942$37K<0.01%new13F-HRTimeline
CIBC WORLD MARKET INC.14,326$35.4K<0.01%-2,68913F-HRTimeline
Invesco Ltd.in group Invesco Ltd.13,662$33.7K<0.01%-1,17413F-HRTimelineGroup
JTC Employer Solutions Trustee Ltd13,249$33K<0.01%new13F-HRTimeline
Virtu Financial LLCin group Virtu Financial LLC12,545$31K<0.01%new13F-HRTimelineGroup
R Squared Ltd12,519$30.9K0.02%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…12,246$30.2K<0.01%+2,33713F-HRTimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…11,420$28.2K<0.01%013F-HRTimeline
Freedom Investment Management, Inc.10,432$25.8K<0.01%new13F-HRTimeline
Creative Planningin group Creative Planning10,145$25.1K<0.01%new13F-HRTimelineGroup
FOGEL CAPITAL MANAGEMENT, INC.10,000$24.7K0.01%new13F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND8,434$20.8K<0.01%013F-HR/ATimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA5,145$13K<0.01%+3,50513F-HR/ATimelineGroup
Legal & General Group Plcin group Legal & General Group Plc4,899$12.1K<0.01%-1,01613F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC4,236$10.5K<0.01%+3,92113F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…3,901$9.63K<0.01%013F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.3,358$8.29K<0.01%013F-HRTimeline
AMALGAMATED BANK1,957$5K<0.01%013F-HRTimeline
Sterling Capital Management LLC1,576$3.89K<0.01%+1,51813F-HR/ATimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC1,564$3.86K<0.01%new13F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…1,362$3.36K<0.01%+35013F-HRTimelineGroup
SIGNATUREFD, LLC1,000$2.47K<0.01%-1,64913F-HRTimeline
Leonteq Securities AG915$2.26K<0.01%013F-HRTimeline
SBI Securities Co., Ltd.727$1.8K<0.01%+15313F-HRTimeline
MAI Capital Management615$1.52K<0.01%new13F-HRTimeline
Fairman Group, LLC500$1.24K<0.01%013F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…482$1.19K<0.01%+43013F-HRTimelineGroup
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.398$1K<0.01%013F-HRTimelineGroup
ROTHSCHILD INVESTMENT LLC345$852<0.01%+3013F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…319$788<0.01%-513F-HRTimelineGroup
Fortitude Family Office, LLC296$731<0.01%new13F-HRTimeline
Parkside Financial Bank & Trust285$700<0.01%new13F-HRTimeline
PRINCIPAL SECURITIES, INC.in group PRINCIPAL FINANCIAL GROUP INC280$692<0.01%013F-HRTimelineGroup
Essential Partners LLC210$519<0.01%13F-HRTimeline
Larson Financial Group LLC200$494<0.01%013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.128$315<0.01%-3613F-HR/ATimelineGroup
True Wealth Design, LLC115$285<0.01%+6513F-HRTimeline
Farther Finance Advisors, LLC26$64<0.01%-10,73713F-HRTimeline
IFP Advisors, Inc8$20<0.01%-1613F-HRTimeline
Covestor Ltd31$00%-213F-HRTimelineValue filed as zero, left out of ratios.
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.