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Disclosery

PRME PRIME MEDICINE INC

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COM (common), issuer CIK 1894562

183 managers (192 13F filers) reported a position in PRME shares at 2026-03-31, 98,565,813 shares in all. 30 filers opened a position and 25 filers sold out during the quarter.

Managers
183
13F filers
192
New
30
Added
74
Reduced
49
Sold out
25
Shares held by filers
98,565,813

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q1 2026

Filers in the available 13F reports with a share position at 2026-03-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Alphabet Inc.in group Alphabet Inc.16,562,498$57.6M1.44%013F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.8,501,708$29.6M<0.01%+232,86513F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP6,345,125$22.1M<0.01%+1,249,61513F-HRTimelineGroup
ARK Investment Management LLCin group ARK Investment Management LLC6,246,827$21.7M0.17%+878,30113F-HRTimelineGroup
VANGUARD GROUP INCgroup of 8 filers holding6,205,070$21.6M+6,181,419Timeline
T. Rowe Price Investment Management, In…5,481,893$19.1M0.01%-513,29013F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management4,123,365$14.3M0.03%+999,00313F-HRTimelineGroup
Casdin Capital, LLC3,167,175$11M0.83%013F-HRTimeline
Woodline Partners LP3,003,313$10.5M0.04%+46913F-HR/ATimeline
UBS Group AGgroup of 2 filers holding2,973,718$10.3M+434,035Timeline
Sumitomo Mitsui Trust Group, Inc.in group Sumitomo Mitsui Trust Group, …2,940,793$10.2M0.01%-304,71313F-HRTimelineGroup
Amova Asset Management Americas, Inc.in group Amova Asset Management Americ…2,940,793$10.2M0.14%-304,71313F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC2,743,700$9.55M<0.01%+115,27113F-HRTimelineGroup
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC1,973,282$6.87M0.41%new13F-HRTimelineGroup
FMR LLCin group FMR LLC1,769,476$6.16M<0.01%-407,17013F-HRTimelineGroup
Redmile Group, LLCin group Redmile Group, LLC1,590,832$5.54M0.37%new13F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP1,572,811$5.47M<0.01%-56,51313F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.1,393,621$4.85M<0.01%-157,74813F-HRTimelineGroup
FARALLON CAPITAL MANAGEMENT, L.L.C.1,240,843$4.32M0.03%013F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC970,425$3.38M<0.01%-785,34313F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co917,212$3.19M<0.01%-19,60313F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP886,716$3.09M<0.01%+44,56313F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO844,154$2.66M<0.01%+408,44413F-HR/ATimelineGroup
Greenwich Wealth Management LLC750,001$2.61M0.11%+10,00013F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC741,039$2.58M<0.01%-408,12013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…715,829$2.49M<0.01%-460,89813F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY639,457$2.23M<0.01%-530,44113F-HRTimelineGroup
HRT FINANCIAL LP612,769$2.13M0.01%-42,58213F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/577,004$2.01M<0.01%-71,00813F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC554,935$1.93M<0.01%+139,11413F-HRTimelineGroup
MOORE CAPITAL MANAGEMENT, LP500,000$1.74M0.06%013F-HRTimeline
CHELSEA COUNSEL CO462,340$1.61M0.72%+235,34013F-HR/ATimeline
Alessandra Capital Management, LLC425,510$1.48M1.26%new13F-HRTimeline
Bollard Group LLC361,136$1.26M0.04%013F-HRTimeline
HighTower Advisors, LLC340,255$1.18M<0.01%-59,85513F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC336,358$1.17M<0.01%+223,48813F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN319,550$1.11M<0.01%+25,05413F-HR/ATimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP304,522$1.06M<0.01%+220,46813F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…278,120$968K<0.01%+29,89313F-HRTimelineGroup
Nuveen, LLCin group TIAA275,931$960K<0.01%+24,29513F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp267,219$930K<0.01%+20,44913F-HRTimelineGroup
Rafferty Asset Management, LLC215,582$750K<0.01%+27,87113F-HRTimeline
IQ EQ FUND MANAGEMENT (IRELAND) Ltd205,389$715K0.05%+26,87013F-HRTimeline
Green Alpha Advisors, LLC191,171$665K0.66%+28813F-HRTimeline
Swiss National Bank178,600$622K<0.01%+8,50013F-HRTimeline
Keystone Financial Group166,010$578K0.04%+36,34513F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\157,440$548K<0.01%+9,49713F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd157,282$547K0.01%+84,34713F-HRTimelineGroup
Elevate Capital Advisors, LLC151,069$526K0.34%+108,40313F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP141,957$494K<0.01%new13F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC134,800$469K0.01%013F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/133,755$466K<0.01%+29,20213F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding131,878$454K+8,046Timeline
ALLIANCEBERNSTEIN L.P.122,460$425K<0.01%+13,77013F-HRTimeline
Steward Partners Investment Advisory, L…117,456$409K<0.01%-95013F-HRTimeline
FIL Ltdin group FIL Ltd115,206$401K<0.01%-39613F-HRTimelineGroup
RHUMBLINE ADVISERS114,269$398K<0.01%+5,86013F-HRTimeline
Engineers Gate Manager LP110,348$384K<0.01%+49,85813F-HRTimeline
Palumbo Wealth Management LLC102,246$356K0.09%+16,70713F-HRTimeline
Invesco Ltd.in group Invesco Ltd.96,875$337K<0.01%+40,09613F-HRTimelineGroup
PROFUND ADVISORS LLC95,806$333K0.01%+26,20113F-HRTimeline
TD Asset Management Inc94,148$328K<0.01%013F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC94,066$327K<0.01%-123,97613F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…91,401$318K<0.01%-29,99013F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…86,473$301K<0.01%-45613F-HRTimeline
Mariner, LLCin group Mariner, LLC78,398$273K<0.01%+42,10813F-HRTimelineGroup
Concurrent Investment Advisors, LLCin group Concurrent Investment Advisor…74,177$258K<0.01%new13F-HRTimelineGroup
IEQ CAPITAL, LLC74,013$258K<0.01%+36,87713F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…66,508$231K0.06%+1,62213F-HRTimelineGroup
LPL Financial LLC66,424$231K<0.01%+33,50013F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc66,444$231K<0.01%-14,30513F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…64,273$224K<0.01%+57,44613F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC63,773$222K<0.01%-300,05313F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL61,546$214K<0.01%new13F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson60,900$212K<0.01%013F-HR/ATimelineGroup
&PARTNERS59,470$207K<0.01%-88213F-HRTimeline
Aquatic Capital Management LLC54,230$189K0.01%new13F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC52,615$183K<0.01%new13F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC49,584$173K<0.01%-4,49813F-HR/ATimelineGroup
CITIGROUP INCin group CITIGROUP INC47,232$164K<0.01%-3,99713F-HRTimelineGroup
Quadrature Capital Ltdin group Quadrature Capital Ltd46,893$163K<0.01%-5,97313F-HRTimelineGroup
Mutual Advisors, LLC45,200$157K<0.01%013F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…44,208$154K<0.01%-13,36213F-HRTimelineGroup
VARCOV Co.41,964$146K0.05%new13F-HRTimeline
IvyRock Asset Management (HK) Ltd41,800$145K0.08%013F-HRTimeline
DRW Securities, LLC40,964$143K0.01%new13F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP40,307$136K<0.01%-9613F-HRTimelineGroup
AXQ CAPITAL, LP36,742$128K0.02%+3,33713F-HRTimeline
WEALTH ENHANCEMENT ADVISORY SERVICES, L…37,681$125K<0.01%+11,58313F-HRTimeline
Kingsview Wealth Management, LLC35,000$122K<0.01%+20,00013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS34,413$120K<0.01%+24,59013F-HRTimelineGroup
CWM, LLCin group CWM, LLC33,811$118K<0.01%+8,38413F-HRTimelineGroup
OPPENHEIMER & CO INCin group OPPENHEIMER ASSET MANAGEMENT …33,656$117K<0.01%+21,22313F-HRTimelineGroup
Crestwood Advisors Group, LLC32,374$113K<0.01%+40113F-HRTimeline
China Universal Asset Management Co., L…32,033$111K0.01%+2,61913F-HRTimeline
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…30,845$107K<0.01%new13F-HRTimelineGroup
Police & Firemen's Retirement System of…30,751$107K<0.01%+9,58513F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC30,538$106K<0.01%-4,49813F-HRTimeline
TRANSCEND CAPITAL ADVISORS, LLC30,070$105K0.01%+3,57013F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO29,183$102K<0.01%new13F-HRTimelineGroup
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC29,040$101K<0.01%-3,53613F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …28,872$100K<0.01%-2,73013F-HRTimelineGroup
Creative Planningin group Creative Planning28,246$98.3K<0.01%+10,35413F-HRTimelineGroup
E Fund Management Co., Ltd.27,099$94.3K<0.01%13F-HRTimeline
BLUE BELL PRIVATE WEALTH MANAGEMENT, LLC27,015$94K0.01%new13F-HRTimeline
Abacus Planning Group, Inc.25,188$87.7K0.01%013F-HRTimeline
Turtle Creek Wealth Advisors, LLC25,000$87K0.01%new13F-HRTimeline
NOMURA HOLDINGS INCin group NOMURA ASSET MANAGEMENT CO LTD24,823$86.4K<0.01%+3413F-HRTimelineGroup
ARIZONA STATE RETIREMENT SYSTEM24,791$86.3K<0.01%+70613F-HRTimeline
GROUP ONE TRADING LLC24,766$86.2K<0.01%-78,44713F-HRTimeline
ProShare Advisors LLC22,968$79.9K<0.01%-3,19013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…21,814$75.9K<0.01%+21,00713F-HRTimelineGroup
SHELTON WEALTH MANAGEMENT, LLC20,066$69.8K0.03%013F-HRTimeline
KLP KAPITALFORVALTNING AS18,500$64.4K<0.01%013F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…18,225$63.4K<0.01%+9,41113F-HRTimeline
Scientech Research LLC17,931$62.4K0.05%-4,46213F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC17,345$60.4K<0.01%-14613F-HRTimelineGroup
THOMPSON DAVIS & CO., INC.17,240$60K0.04%-5,50013F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC16,437$57.2K<0.01%-17,96213F-HRTimeline
Graham Capital Management, L.P.16,015$55.7K<0.01%-98,66513F-HRTimeline
Magnetar Financial LLCin group Magnetar Financial LLC15,784$54.9K<0.01%new13F-HRTimelineGroup
LEVIN CAPITAL STRATEGIES, L.P.15,000$52.2K<0.01%013F-HRTimeline
MARTINGALE ASSET MANAGEMENT L P14,848$51.7K<0.01%+4013F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC14,755$51.3K<0.01%new13F-HRTimelineGroup
Sanctuary Advisors, LLC13,894$48.4K<0.01%-76513F-HRTimeline
BENJAMIN EDWARDS INCin group BENJAMIN EDWARDS INC13,852$48.2K<0.01%new13F-HRTimelineGroup
Sterling Investment Advisors, Ltd.13,400$46.6K0.01%013F-HRTimeline
JTC Employer Solutions Trustee Ltd13,249$46K<0.01%013F-HRTimeline
Prime Capital Investment Advisors, LLC12,945$45K<0.01%-1,11013F-HRTimeline
Cambridge Investment Research Advisors,…12,337$43K<0.01%new13F-HRTimeline
MERCER GLOBAL ADVISORS INC /ADV12,305$42.8K<0.01%new13F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…12,107$42.1K<0.01%new13F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC12,044$41.9K<0.01%-15,00013F-HRTimelineGroup
Sequoia Financial Advisors, LLC11,673$40.6K<0.01%new13F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS11,058$38.5K<0.01%-1,17713F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC10,817$37.6K<0.01%+1613F-HRTimeline
Wealthfront Advisers LLC10,379$36.1K<0.01%new13F-HRTimeline
Polymer Capital Management (US) LLC10,317$35.9K0.01%-25,66413F-HRTimeline
Forum Financial Management, LPin group Forum Financial Management, LP10,000$34.8K<0.01%013F-HRTimelineGroup
Glen Eagle Advisors, LLC10,000$34.8K<0.01%013F-HRTimeline
Federation des caisses Desjardins du Qu…9,500$33.1K<0.01%-2,50013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC9,346$32.5K<0.01%+4,80013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA9,254$32K<0.01%+4,36513F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND8,434$29.4K<0.01%013F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…8,407$29.3K<0.01%+2,50613F-HRTimelineGroup
LANARK FINANCIAL, INC.5,000$17.4K<0.01%013F-HRTimeline
SIGNATUREFD, LLC5,000$17.4K<0.01%013F-HRTimeline
Allworth Financial LP4,405$15.3K<0.01%+1,29013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.4,097$14.3K<0.01%-4,33113F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.4,036$14K<0.01%+48913F-HRTimeline
Sterling Capital Management LLC3,462$12K<0.01%-2,27413F-HRTimeline
Financial Connections Group, Inc.3,712$12K<0.01%013F-HRTimeline
MTM Investment Management, LLC3,090$10.8K<0.01%013F-HRTimeline
Owl Creek Wealth Partners LLC2,615$9.1K<0.01%13F-HRTimeline
Corient Private Wealth LPin group Corient Private Wealth LP41,221$8.64K<0.01%+2,44413F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…2,000$6.96K<0.01%+23813F-HR/ATimelineGroup
Scarborough Advisors, LLC1,258$4.38K<0.01%+113F-HRTimeline
Essential Partners LLC1,008$3.51K<0.01%+78713F-HRTimeline
NewEdge Advisors, LLC1,000$3.48K<0.01%013F-HR/ATimeline
Optiver Holding B.V.in group Optiver Holding B.V.892$3.1K<0.01%+73213F-HR/ATimelineGroup
GAMMA Investing LLC647$2.25K<0.01%+53613F-HRTimeline
Fairman Group, LLC500$1.74K<0.01%013F-HRTimeline
Fortitude Family Office, LLC436$1.52K<0.01%+14013F-HRTimeline
SBI Securities Co., Ltd.391$1.36K<0.01%+8813F-HRTimeline
MAI Capital Management386$1.34K<0.01%+11213F-HRTimeline
Caitong International Asset Management …383$1.33K<0.01%-38,31313F-HRTimeline
ROTHSCHILD INVESTMENT LLC382$1.33K<0.01%+3713F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…319$1.11K<0.01%013F-HRTimelineGroup
Basecamp Wealth Advisors LLC287$999<0.01%013F-HRTimeline
Parkside Financial Bank & Trust285$992<0.01%013F-HRTimeline
Arax Advisory Partners230$800<0.01%new13F-HRTimeline
True Wealth Design, LLC152$529<0.01%+3713F-HRTimeline
Farther Finance Advisors, LLC154$522<0.01%+8313F-HRTimeline
Sunbelt Securities, Inc.80$278<0.01%013F-HRTimeline
HARBOUR INVESTMENTS, INC.74$258<0.01%new13F-HRTimeline
Keating Financial Advisory Services, In…59$205<0.01%new13F-HRTimeline
NFSG Corp45$157<0.01%new13F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\33$115<0.01%new13F-HRTimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/10$35<0.01%new13F-HRTimelineGroup
SJS Investment Consulting Inc.10$35<0.01%new13F-HRTimeline
TWIN PEAKS WEALTH ADVISORS, LLC3$10<0.01%new13F-HRTimeline
IFP Advisors, Inc2$7<0.01%-813F-HRTimeline
Covestor Ltd31$00%013F-HRTimelineValue filed as zero, left out of ratios.