RA CAPITAL MANAGEMENT, L.P. in group RA CAPITAL MANAGEMENT, L.P. More: the full row for RA CAPITAL MANAGEMENT, L.P. 20,064,545 $35.5M 0.38% 0 13F-HR Timeline Group Commodore Capital LP in group Commodore Capital LP More: the full row for Commodore Capital LP 4,475,000 $7.92M 0.46% +1,075,000 13F-HR Timeline Group VIKING GLOBAL INVESTORS LP in group VIKING GLOBAL INVESTORS LP More: the full row for VIKING GLOBAL INVESTORS LP 3,482,434 $6.16M 0.02% 0 13F-HR Timeline Group Laurion Capital Management LP More: the full row for Laurion Capital Management LP 2,750,855 $4.87M 0.46% +698,722 13F-HR Timeline Vivo Capital, LLC More: the full row for Vivo Capital, LLC 2,325,000 $4.12M 0.34% 0 13F-HR/A Timeline VANGUARD GROUP INC group of 3 filers holding More: the full row for VANGUARD GROUP INC 2,215,119 $3.92M new Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 2,079,143 $3.68M <0.01% +1,881,200 13F-HR Timeline Group AWM Investment Company, Inc. More: the full row for AWM Investment Company, Inc. 1,830,925 $3.24M 0.36% +530,925 13F-HR Timeline ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 1,607,638 $2.85M 0.17% +1,570,796 13F-HR Timeline Group Woodline Partners LP More: the full row for Woodline Partners LP 1,311,021 $2.32M 0.01% 0 13F-HR/A Timeline Pictet Asset Management Holding SA in group Pictet Asset Management Holdi… More: the full row for Pictet Asset Management Holding SA 1,306,783 $2.31M <0.01% -45,641 13F-HR Timeline Group BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 1,277,784 $2.26M <0.01% +43,370 13F-HR Timeline Group Kalehua Capital Management LLC More: the full row for Kalehua Capital Management LLC 1,000,000 $1.77M 1.25% new 13F-HR/A Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 998,987 $1.77M <0.01% -85,413 13F-HR Timeline Group Qube Research & Technologies Ltd More: the full row for Qube Research & Technologies Ltd 706,472 $1.25M <0.01% +675,238 13F-HR Timeline Nantahala Capital Management, LLC in group Nantahala Capital Management,… More: the full row for Nantahala Capital Management, LLC 681,158 $1.21M 0.08% -866,071 13F-HR Timeline Group MONIMUS CAPITAL MANAGEMENT, LP More: the full row for MONIMUS CAPITAL MANAGEMENT, LP 598,663 $1.06M 0.29% +460,265 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 535,999 $949K <0.01% -6,110 13F-HR Timeline Group Creek Drive Management Group LLC More: the full row for Creek Drive Management Group LLC 450,000 $796K 0.5% new 13F-HR Timeline Ikarian Capital, LLC in group Ikarian Capital, LLC More: the full row for Ikarian Capital, LLC 447,165 $791K 0.11% 0 13F-HR Timeline Group SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 442,168 $783K <0.01% +316,670 13F-HR Timeline Group BOOTHBAY FUND MANAGEMENT, LLC More: the full row for BOOTHBAY FUND MANAGEMENT, LLC 351,374 $622K 0.01% -66,622 13F-HR Timeline MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 298,568 $528K <0.01% +7,979 13F-HR Timeline Group Driehaus Capital Management LLC More: the full row for Driehaus Capital Management LLC 279,909 $495K <0.01% -35,091 13F-HR Timeline Boxer Capital Management, LLC in group Boxer Capital Management, LLC More: the full row for Boxer Capital Management, LLC 272,892 $483K 0.06% -101,000 13F-HR Timeline Group STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 229,390 $406K <0.01% +11,900 13F-HR Timeline Group DIMENSIONAL FUND ADVISORS LP in group DIMENSIONAL FUND ADVISORS LP More: the full row for DIMENSIONAL FUND ADVISORS LP 216,824 $394K <0.01% +81,608 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 207,922 $368K <0.01% -59,867 13F-HR Timeline Group Artia Global Partners LP More: the full row for Artia Global Partners LP 205,324 $363K 0.08% 0 13F-HR Timeline JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 197,391 $349K <0.01% +4,658 13F-HR Timeline Group TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 181,705 $322K <0.01% -85,720 13F-HR Timeline Group Quadrature Capital Ltd in group Quadrature Capital Ltd More: the full row for Quadrature Capital Ltd 158,826 $281K <0.01% new 13F-HR Timeline Group DIADEMA PARTNERS LP More: the full row for DIADEMA PARTNERS LP 150,925 $267K 0.11% new 13F-HR Timeline LUMINUS MANAGEMENT LLC More: the full row for LUMINUS MANAGEMENT LLC 150,000 $266K 0.16% new 13F-HR Timeline Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 146,596 $259K <0.01% +115,383 13F-HR Timeline Group GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 138,653 $245K <0.01% -102,965 13F-HR Timeline Group XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 131,151 $232K <0.01% +33,115 13F-HR Timeline Group WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 121,974 $216K <0.01% new 13F-HR Timeline Group READYSTATE ASSET MANAGEMENT LP More: the full row for READYSTATE ASSET MANAGEMENT LP 115,116 $204K 0.01% +1,614 13F-HR Timeline NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 104,899 $186K <0.01% -13,358 13F-HR Timeline Group RBF Capital, LLC More: the full row for RBF Capital, LLC 95,042 $168K 0.01% 0 13F-HR/A Timeline UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 94,030 $166K <0.01% +85,962 13F-HR Timeline Group ExodusPoint Capital Management, LP More: the full row for ExodusPoint Capital Management, LP 79,581 $141K <0.01% -41,147 13F-HR Timeline Hudson Bay Capital Management LP in group Hudson Bay Capital Management… More: the full row for Hudson Bay Capital Management LP 69,593 $123K <0.01% +202 13F-HR Timeline Group Connor, Clark & Lunn Investment Managem… More: the full row for Connor, Clark & Lunn Investment Management Ltd. 69,123 $122K <0.01% -4,183 13F-HR Timeline Rangeley Capital, LLC More: the full row for Rangeley Capital, LLC 68,096 $121K 0.13% +31,896 13F-HR Timeline Brevan Howard Capital Management LP in group Brevan Howard Capital Managem… More: the full row for Brevan Howard Capital Management LP 66,402 $118K <0.01% new 13F-HR Timeline Group Point72 Asset Management, L.P. in group Point72 Asset Management, L.P. More: the full row for Point72 Asset Management, L.P. 65,972 $117K <0.01% -2,208,444 13F-HR Timeline Group BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 63,732 $113K <0.01% -25,843 13F-HR Timeline Group ACADIAN ASSET MANAGEMENT LLC in group ACADIAN ASSET MANAGEMENT LLC More: the full row for ACADIAN ASSET MANAGEMENT LLC 64,607 $112K <0.01% +43,769 13F-HR Timeline Group LANDSCAPE CAPITAL MANAGEMENT, L.L.C. in group LANDSCAPE CAPITAL MANAGEMENT,… More: the full row for LANDSCAPE CAPITAL MANAGEMENT, L.L.C. 61,073 $108K 0.01% +24,948 13F-HR Timeline Group Seven Fleet Capital Management LP More: the full row for Seven Fleet Capital Management LP 59,500 $105K 0.03% new 13F-HR/A Timeline RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 56,800 $101K <0.01% -91,100 13F-HR Timeline Verdad Advisers, LP More: the full row for Verdad Advisers, LP 54,380 $96.3K 0.11% new 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 53,316 $94.4K <0.01% -297,825 13F-HR Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 45,130 $79.9K <0.01% -10,587 13F-HR Timeline Group BRIDGEWAY CAPITAL MANAGEMENT, LLC More: the full row for BRIDGEWAY CAPITAL MANAGEMENT, LLC 43,700 $77.3K <0.01% -19,300 13F-HR Timeline GROUP ONE TRADING LLC More: the full row for GROUP ONE TRADING LLC 43,537 $77.1K <0.01% new 13F-HR Timeline AMERICAN CENTURY COMPANIES INC in group AMERICAN CENTURY COMPANIES INC More: the full row for AMERICAN CENTURY COMPANIES INC 42,601 $75.4K <0.01% +26,851 13F-HR Timeline Group Scientech Research LLC More: the full row for Scientech Research LLC 42,073 $74.5K 0.06% new 13F-HR Timeline GSA CAPITAL PARTNERS LLP More: the full row for GSA CAPITAL PARTNERS LLP 38,286 $68K <0.01% -5,154 13F-HR Timeline Persistent Asset Partners Ltd More: the full row for Persistent Asset Partners Ltd 38,152 $67.5K 0.03% new 13F-HR Timeline Rathbones Group PLC More: the full row for Rathbones Group PLC 32,003 $56.6K <0.01% 0 13F-HR/A Timeline CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 27,012 $47.8K <0.01% new 13F-HR Timeline Group OMERS ADMINISTRATION Corp More: the full row for OMERS ADMINISTRATION Corp 24,900 $44.1K <0.01% -2,700 13F-HR Timeline MANGROVE PARTNERS IM, LLC More: the full row for MANGROVE PARTNERS IM, LLC 19,774 $35K <0.01% new 13F-HR Timeline Virtu Financial LLC in group Virtu Financial LLC More: the full row for Virtu Financial LLC 18,974 $34K <0.01% new 13F-HR Timeline Group Schonfeld Strategic Advisors LLC More: the full row for Schonfeld Strategic Advisors LLC 17,400 $30.8K <0.01% new 13F-HR Timeline Catalyst Funds Management Pty Ltd More: the full row for Catalyst Funds Management Pty Ltd 15,300 $27.1K <0.01% new 13F-HR Timeline Diametric Capital, LP More: the full row for Diametric Capital, LP 15,221 $26.9K 0.01% new 13F-HR Timeline Balyasny Asset Management L.P. in group Balyasny Asset Management More: the full row for Balyasny Asset Management L.P. 14,293 $25.3K <0.01% -851,976 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 5,185 $21.9K <0.01% -56 13F-HR/A Timeline Group China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 12,200 $21.6K <0.01% +998 13F-HR Timeline Jefferies Financial Group Inc. in group Jefferies Financial Group Inc. More: the full row for Jefferies Financial Group Inc. 10,289 $18.2K <0.01% -3,440 13F-HR Timeline Group PRELUDE CAPITAL MANAGEMENT, LLC More: the full row for PRELUDE CAPITAL MANAGEMENT, LLC 10,153 $18K <0.01% new 13F-HR Timeline Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 5,540 $9.81K <0.01% -3,949 13F-HR Timeline Group Mirae Asset Global Investments Co., Ltd. in group Mirae Asset Global Investment… More: the full row for Mirae Asset Global Investments Co., Ltd. 3,586 $6.35K <0.01% +245 13F-HR/A Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 2,506 $4.44K <0.01% -28,831 13F-HR Timeline Group Zurcher Kantonalbank (Zurich Cantonalba… More: the full row for Zurcher Kantonalbank (Zurich Cantonalbank) 2,006 $3.55K <0.01% new 13F-HR Timeline FMR LLC in group FMR LLC More: the full row for FMR LLC 1,664 $2.94K <0.01% 0 13F-HR Timeline Group GF FUND MANAGEMENT CO. LTD. More: the full row for GF FUND MANAGEMENT CO. LTD. 1,533 $2.71K <0.01% +183 13F-HR Timeline ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 982 $2K <0.01% +599 13F-HR Timeline Group JONES FINANCIAL COMPANIES LLLP in group JONES FINANCIAL COMPANIES LLLP More: the full row for JONES FINANCIAL COMPANIES LLLP 326 $1.47K <0.01% new 13F-HR Timeline Group Accent Capital Management, LLC More: the full row for Accent Capital Management, LLC 718 $1.27K <0.01% new 13F-HR/A Timeline NISA INVESTMENT ADVISORS, LLC More: the full row for NISA INVESTMENT ADVISORS, LLC 195 $345 <0.01% 0 13F-HR Timeline Parallel Advisors, LLC More: the full row for Parallel Advisors, LLC 135 $239 <0.01% 0 13F-HR/A Timeline Cornerstone Financial Management LLC More: the full row for Cornerstone Financial Management LLC 121 $214 <0.01% 0 13F-HR/A Timeline Fortitude Family Office, LLC More: the full row for Fortitude Family Office, LLC 112 $198 <0.01% new 13F-HR Timeline Bare Financial Services, Inc More: the full row for Bare Financial Services, Inc 102 $181 <0.01% new 13F-HR Timeline Allworth Financial LP More: the full row for Allworth Financial LP 68 $121 <0.01% +40 13F-HR Timeline CWM, LLC in group CWM, LLC More: the full row for CWM, LLC 5 $9 <0.01% 0 13F-HR Timeline Group NOMURA ASSET MANAGEMENT CO LTD in group NOMURA ASSET MANAGEMENT CO LTD More: the full row for NOMURA ASSET MANAGEMENT CO LTD 0 $0 0% 0 13F-HR Timeline Group Value filed as zero, left out of ratios. Amount filed as zero, left out of ratios.