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Disclosery

OPRX OPTIMIZERX CORP

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COM NEW (common), issuer CIK 1448431

128 managers (129 13F filers) reported a position in OPRX shares at 2025-12-31, 13,344,527 shares in all. 25 filers opened a position and 22 filers sold out during the quarter.

Managers
128
13F filers
129
New
25
Added
39
Reduced
39
Sold out
22
Shares held by filers
13,344,527

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Whetstone Capital Advisors, LLC1,508,303$18.5M5.77%013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.1,194,711$14.6M<0.01%+6,87013F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC1,136,933$13.9M<0.01%+77,82413F-HRTimelineGroup
ROYCE & ASSOCIATES LP682,030$8.36M0.08%+4,70013F-HRTimeline
KENNEDY CAPITAL MANAGEMENT LLC673,920$8.26M0.17%-99813F-HRTimeline
RICE HALL JAMES & ASSOCIATES, LLC590,674$7.24M0.4%+44,85813F-HRTimeline
BLAIR WILLIAM & CO/IL582,585$7.14M0.02%-8,55413F-HRTimeline
Parkman Healthcare Partners LLC538,649$6.6M0.63%+29,03813F-HRTimeline
NEXT CENTURY GROWTH INVESTORS LLC505,407$6.2M0.43%+294,68813F-HRTimeline
STATE STREET CORPin group STATE STREET CORP477,531$5.85M<0.01%+84,80813F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP460,909$5.65M<0.01%+63,60713F-HRTimelineGroup
Manatuck Hill Partners, LLC422,107$5.18M1.81%-50,20013F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC396,468$4.86M<0.01%+13,29113F-HRTimelineGroup
G2 Investment Partners Management LLC310,000$3.8M0.9%+130,26413F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…289,060$3.54M<0.01%+75,76213F-HRTimelineGroup
AWM Investment Company, Inc.230,421$2.82M0.27%013F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC206,961$2.54M0.01%+67,88413F-HRTimelineGroup
Bullseye Asset Management LLC206,527$2.53M1.36%013F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY164,592$2.02M<0.01%-17,68613F-HR/ATimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP156,927$1.92M<0.01%-5,23613F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC127,014$1.56M<0.01%-9,45013F-HR/ATimelineGroup
Granahan Investment Management, LLC117,122$1.44M0.06%+46,07613F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp114,258$1.4M<0.01%+26,30113F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.112,867$1.38M<0.01%-208,18413F-HRTimelineGroup
Schonfeld Strategic Advisors LLC98,170$1.2M0.01%+36,52213F-HRTimeline
Calamos Advisors LLCin group Calamos Advisors LLC97,118$1.19M<0.01%+20,11613F-HRTimelineGroup
Inspire Investing, LLCin group Inspire Investing, LLC95,880$1.18M0.11%new13F-HRTimelineGroup
CREDIT AGRICOLE S Ain group CREDIT AGRICOLE S A89,200$1.09M<0.01%new13F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC87,481$1.07M<0.01%new13F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC82,414$1.01M<0.01%-2,35813F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co81,318$997K<0.01%+6,19113F-HRTimelineGroup
AVENIR CORP77,260$947K0.1%013F-HRTimeline
BOOTHBAY FUND MANAGEMENT, LLC73,488$901K0.02%+25,50213F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC44,577$874K<0.01%-3,91313F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC69,029$846K0.02%+10,00013F-HRTimeline
Qube Research & Technologies Ltd59,161$725K<0.01%+40,57813F-HRTimeline
P.A.W. CAPITAL CORP55,000$674K1.53%+5,00013F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO53,789$659K<0.01%new13F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD53,094$651K<0.01%+25,53313F-HRTimeline
TWO SIGMA INVESTMENTS, LPin group TWO SIGMA INVESTMENTS, LP46,181$566K<0.01%-17,52313F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC43,669$535K<0.01%new13F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/42,576$522K<0.01%-42,18413F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.39,850$489K<0.01%013F-HRTimeline
Nuveen, LLCin group TIAA38,786$476K<0.01%-5,33713F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding35,599$436K+1,513Timeline
Diametric Capital, LP33,263$408K0.11%new13F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC31,495$386K<0.01%-54,99013F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…29,741$365K<0.01%new13F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC29,578$363K<0.01%-78,32213F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN28,903$354K<0.01%+7,57613F-HRTimelineGroup
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC27,531$338K<0.01%+8,70513F-HRTimelineGroup
RHUMBLINE ADVISERS27,451$337K<0.01%-4,96313F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC27,441$336K<0.01%+4,31713F-HRTimelineGroup
LPL Financial LLC26,698$327K<0.01%-1,67713F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC25,351$311K<0.01%-44,05513F-HRTimelineGroup
CenterBook Partners LP25,224$309K0.02%-283,58513F-HRTimeline
HARBOR CAPITAL ADVISORS, INC.24,876$305K0.02%+2,70813F-HRTimeline
STRS OHIO24,500$300K<0.01%013F-HRTimeline
GWN SECURITIES INC.22,358$274K0.06%new13F-HRTimeline
Hillsdale Investment Management Inc.20,300$249K0.01%+2,00013F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP19,825$243K<0.01%-15,58213F-HRTimelineGroup
Engineers Gate Manager LP18,634$228K<0.01%new13F-HRTimeline
Quantinno Capital Management LP17,504$215K<0.01%+3,15713F-HRTimeline
PERKINS CAPITAL MANAGEMENT INC17,408$213K0.17%-20,18813F-HRTimeline
HRT FINANCIAL LP17,295$212K<0.01%new13F-HRTimeline
INDEPENDENT FINANCIAL GROUP, LLC16,500$202K<0.01%new13F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources16,284$200K<0.01%-12,34613F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC14,514$178K<0.01%+2,25613F-HRTimelineGroup
CANADA PENSION PLAN INVESTMENT BOARD13,900$170K<0.01%new13F-HRTimeline
Campbell & CO Investment Adviser LLC12,908$158K0.01%new13F-HRTimeline
GSA CAPITAL PARTNERS LLP12,604$155K0.01%new13F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\12,397$152K<0.01%+73313F-HRTimelineGroup
ExodusPoint Capital Management, LP12,252$150K<0.01%new13F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC11,976$147K<0.01%-96,81513F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.11,965$147K<0.01%new13F-HRTimelineGroup
PRELUDE CAPITAL MANAGEMENT, LLC11,063$136K0.01%new13F-HRTimeline
Worth Venture Partners, LLC10,750$132K0.95%013F-HRTimeline
State of Wyoming10,535$129K0.01%-11,29813F-HRTimeline
Quantbot Technologies LP9,847$121K<0.01%new13F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…9,844$121K<0.01%-1,53513F-HRTimelineGroup
VIRTUS ADVISERS, LLCin group Virtus Investment Advisers, L…9,687$119K0.06%-15,50013F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO8,173$100K<0.01%+1,60913F-HRTimelineGroup
GROUP ONE TRADING LLC8,051$98.7K<0.01%-1,62313F-HRTimeline
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…7,356$90.2K<0.01%+12613F-HRTimelineGroup
MAI Capital Management5,700$69.9K<0.01%013F-HRTimeline
FMR LLCin group FMR LLC5,591$68.5K<0.01%-27713F-HRTimelineGroup
State of Alaska, Department of Revenue5,067$62K<0.01%new13F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND5,034$61.7K<0.01%013F-HRTimeline
Police & Firemen's Retirement System of…4,583$56.2K<0.01%013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS4,257$52.2K<0.01%+33113F-HRTimelineGroup
SIMPLEX TRADING, LLC4,091$50.2K<0.01%+3,39713F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…2,147$26.3K<0.01%+1,15613F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC2,121$26K<0.01%013F-HRTimeline
Avalon Trust Co2,000$24.5K<0.01%013F-HRTimeline
Covestor Ltd1,914$23K0.01%013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA1,851$23K<0.01%-1,11213F-HRTimelineGroup
Versant Capital Management, Inc1,793$22K<0.01%013F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc1,580$19.4K<0.01%-7813F-HRTimelineGroup
BARD ASSOCIATES INC1,480$18.1K<0.01%new13F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…1,258$15.4K<0.01%013F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.1,227$15K<0.01%-1,44513F-HRTimelineGroup
Steward Partners Investment Advisory, L…1,000$12.3K<0.01%013F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…972$11.9K<0.01%-30213F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP760$9.32K<0.01%013F-HRTimelineGroup
CWM, LLCin group CWM, LLC683$8K<0.01%-1813F-HRTimelineGroup
MCF Advisors LLC631$7.74K<0.01%+36113F-HRTimeline
GAMMA Investing LLC565$6.93K<0.01%+913F-HRTimeline
AMALGAMATED BANK496$6K<0.01%-9613F-HRTimeline
Compagnie Lombard Odier SCmA410$5.03K<0.01%013F-HRTimeline
CITIGROUP INCin group CITIGROUP INC358$4.39K<0.01%-62413F-HRTimelineGroup
SBI Securities Co., Ltd.253$3.1K<0.01%-2013F-HRTimeline
Leonteq Securities AG139$1.7K<0.01%013F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.132$1.62K<0.01%013F-HRTimelineGroup
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.112$1.37K<0.01%-24013F-HRTimelineGroup
Sterling Capital Management LLC103$1.26K<0.01%+6513F-HRTimeline
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…100$1.23K<0.01%new13F-HR/ATimelineGroup
AdvisorNet Financial, Inc100$1.23K<0.01%013F-HRTimeline
HighMark Wealth Management LLC100$1.23K<0.01%013F-HRTimeline
Torren Management, LLC97$1.19K<0.01%13F-HRTimeline
Arax Advisory Partners90$1.1K<0.01%-23513F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…62$760<0.01%-19713F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…29$355<0.01%-213F-HRTimelineGroup
True Wealth Design, LLC14$172<0.01%013F-HRTimeline
Sunbelt Securities, Inc.11$135<0.01%013F-HRTimeline
Farther Finance Advisors, LLC10$123<0.01%013F-HRTimeline
ROTHSCHILD INVESTMENT LLC5$61<0.01%new13F-HRTimeline
IFP Advisors, Inc2$25<0.01%new13F-HRTimeline
Pinnacle Wealth Planning Services, Inc.1$12<0.01%new13F-HRTimeline