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TWO SIGMA INVESTMENTS, LP: OPRX position timeline

Available 13F reports, 13D and 13G stakes and each Form 3, 4 and 5 line of TWO SIGMA INVESTMENTS, LP on OPRX, newest first. How the timeline and the estimate are built.

TWO SIGMA INVESTMENTS, LP held 0 OPRX shares at 2026-03-31 per its 13F-HR filed 2026-05-15.

the latest 13F is the newest step

  1. period ended2026-03-31
    13F 0 shares
    Change vs previous 13F -46,181 shares

    13F-HR 0000899140-26-000547 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

    Exited: the 13F for this period no longer lists the position.

  2. period ended2025-12-31
    13F 46,181 shares
    Change vs previous 13F -17,523 shares

    <0.01% of the 13F portfolio, value $566,179.

    13F-HR 0000899140-26-000232 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  3. period ended2025-09-30
    13F 63,704 shares
    Change vs previous 13F -62,064 shares

    <0.01% of the 13F portfolio, value $1,305,932.

    13F-HR 0000899140-25-001286 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 63,704 shares
    • TWO SIGMA ADVISERS, LP: 0 shares

    Acceptance time not in the bulk data set (spec §4.2).

  4. period ended2025-06-30
    13F 125,768 shares
    Change vs previous 13F +76,732 shares

    <0.01% of the 13F portfolio, value $1,697,869.

    13F-HR 0000899140-25-000964 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 102,745 shares
    • TWO SIGMA ADVISERS, LP: 23,023 shares

    Acceptance time not in the bulk data set (spec §4.2).

  5. period ended2025-03-31
    13F 49,036 shares
    Change vs previous 13F not available

    <0.01% of the 13F portfolio, value $424,652.

    13F-HR 0000899140-25-000680 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).