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Disclosery

OPK OPKO HEALTH INC

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COM (common), issuer CIK 944809

217 managers (221 13F filers) reported a position in OPK shares at 2025-12-31, 199,586,691 shares in all. 24 filers opened a position and 33 filers sold out during the quarter.

Managers
217
13F filers
221
New
24
Added
43
Reduced
77
Sold out
33
Shares held by filers
199,586,691

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Rubric Capital Management LP47,791,243$60.2M0.72%013F-HRTimeline
BlackRock, Inc.in group BlackRock, Inc.34,852,030$43.9M<0.01%+1,679,64613F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC32,457,788$40.9M<0.01%-5,078,10913F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC11,061,318$13.9M<0.01%+67,97313F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP8,951,762$11.3M<0.01%-46,17813F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding6,026,349$7.59M+577,248Timeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC5,986,913$7.54M<0.01%+3,600,37813F-HR/ATimelineGroup
Whitefort Capital Management, LP4,253,340$5.36M1.62%-646,66013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co3,692,650$4.65M<0.01%-76,28413F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP3,438,312$4.33M<0.01%-219,53413F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC2,857,433$3.6M<0.01%+2,577,55813F-HRTimelineGroup
AWM Investment Company, Inc.2,100,000$2.65M0.26%-100,00013F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC2,026,957$2.55M<0.01%-846,45913F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC1,775,336$2.24M<0.01%+1,512,49813F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP1,611,318$2.03M<0.01%-56,05013F-HRTimelineGroup
WASHINGTON GROWTH STRATEGIES LLC1,356,124$1.71M1.1%013F-HRTimeline
Y.D. More Investments Ltdin group Y.D. More Investments Ltd1,306,452$1.67M0.08%-192,66613F-HRTimelineGroup
PFG Investments, LLC1,320,391$1.66M0.08%-16,98413F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp1,310,094$1.65M<0.01%+33,22613F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC1,102,174$1.39M<0.01%-115,82813F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding925,948$1.17M-673,796Timeline
MORGAN STANLEYin group MORGAN STANLEY917,353$1.16M<0.01%+79,75213F-HR/ATimelineGroup
Clearstead Advisors, LLC882,367$1.11M0.01%new13F-HRTimeline
Tejara Capital Ltd877,941$1.11M0.46%013F-HRTimeline
Swiss National Bank845,755$1.07M<0.01%013F-HRTimeline
Nuveen, LLCin group TIAA841,836$1.06M<0.01%013F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.781,672$985K<0.01%-235,88913F-HRTimelineGroup
HRT FINANCIAL LP675,483$851K<0.01%new13F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC663,236$836K<0.01%+75,48313F-HRTimelineGroup
Assenagon Asset Management S.A.652,066$835K<0.01%-38,13413F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC641,456$808K<0.01%+49,12613F-HRTimeline
GSA CAPITAL PARTNERS LLP621,328$783K0.07%new13F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/618,259$779K<0.01%-695,62313F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO579,778$731K<0.01%+52,36713F-HRTimelineGroup
RHUMBLINE ADVISERS511,479$644K<0.01%-43,90313F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN468,518$590K<0.01%+126,03213F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc453,265$571K<0.01%+66,42813F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.448,190$565K<0.01%-27,00013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…437,287$551K<0.01%+139,45213F-HRTimelineGroup
Connor, Clark & Lunn Investment Managem…430,630$543K<0.01%+37,86913F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…417,088$526K<0.01%+1,70213F-HRTimeline
TWO SIGMA SECURITIES, LLC374,468$472K0.06%+253,37413F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/367,191$463K<0.01%+23,90513F-HRTimeline
GAMCO Investors (Gabelli)group of 2 filers holding345,000$435K0Timeline
XTX Topco Ltdin group XTX Topco Ltd342,757$432K0.01%new13F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\325,889$411K<0.01%+50,70113F-HRTimelineGroup
EntryPoint Capital, LLC309,024$389K0.15%+270,19613F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC265,268$334K<0.01%new13F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA261,020$329K<0.01%-11,84613F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL244,821$308K<0.01%013F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …229,590$289K<0.01%-7,13213F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson206,314$259K<0.01%013F-HRTimelineGroup
Balyasny Asset Management L.P.in group Balyasny Asset Management198,821$251K<0.01%new13F-HRTimelineGroup
MIRABELLA FINANCIAL SERVICES LLP193,722$244K0.02%new13F-HRTimeline
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…191,104$241K<0.01%-8213F-HRTimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…176,260$222K<0.01%013F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…175,676$221K<0.01%-31,49913F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC159,652$201K<0.01%+16,32913F-HRTimeline
IEQ CAPITAL, LLC157,779$199K<0.01%-119,81513F-HRTimeline
ProShare Advisors LLC156,354$197K<0.01%+85,98513F-HRTimeline
ZAZOVE ASSOCIATES LLC150,000$189K0.02%-57,60013F-HRTimeline
Teton Advisors, LLC140,000$176K0.12%-2,00013F-HRTimeline
VAN ECK ASSOCIATES CORPin group VAN ECK ASSOCIATES CORP137,019$173K<0.01%+25,19313F-HRTimelineGroup
Quantbot Technologies LP122,747$155K0.01%new13F-HRTimeline
COMERICA BANK120,000$151K<0.01%+8,00013F-HRTimeline
Graham Capital Management, L.P.119,654$151K0.01%+21,28613F-HRTimeline
HIGHLINE WEALTH PARTNERS LLC116,681$147K0.04%013F-HRTimeline
Virtu Financial LLCin group Virtu Financial LLC115,298$145K0.01%new13F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND114,301$144K<0.01%-16,60013F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM113,834$143K<0.01%-14,77413F-HRTimeline
GLENMEDE TRUST CO NAin group GLENMEDE TRUST CO NA113,483$143K<0.01%13F-HRTimelineGroup
Y-Intercept (Hong Kong) Ltd112,930$142K<0.01%new13F-HRTimeline
SIH Partners, LLLPin group SIH Partners, LLLP104,334$131K0.01%-45,79113F-HRTimelineGroup
Qube Research & Technologies Ltd102,763$129K<0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…102,397$129K<0.01%013F-HRTimeline
RPg Family Wealth Advisory, LLC98,990$125K0.03%013F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC96,242$121K<0.01%+1,00113F-HRTimelineGroup
SIMPLEX TRADING, LLC93,881$118K<0.01%-56,68513F-HRTimeline
Quadrature Capital Ltdin group Quadrature Capital Ltd91,702$116K<0.01%new13F-HRTimelineGroup
KLP KAPITALFORVALTNING AS90,700$114K<0.01%+16,70013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS90,433$114K<0.01%-27,87613F-HRTimelineGroup
Cambridge Investment Research Advisors,…89,721$113K<0.01%-6,79013F-HRTimeline
Headlands Technologies LLC88,962$112K0.01%+43,72213F-HRTimeline
360 Financial, Inc.87,300$110K0.03%-4,00013F-HR/ATimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…85,348$108K<0.01%new13F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.75,315$94.9K<0.01%-11,46013F-HRTimelineGroup
CWM, LLCin group CWM, LLC69,147$87K<0.01%-55,62713F-HRTimelineGroup
World Investment Advisors66,520$83.8K<0.01%+25,90213F-HR/ATimeline
Cascade Financial Partners, LLC66,490$83.8K0.01%013F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…65,495$82.5K<0.01%013F-HRTimelineGroup
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…61,502$77K<0.01%013F-HRTimeline
WEALTH ENHANCEMENT ADVISORY SERVICES, L…57,529$75.9K<0.01%-18,22013F-HRTimeline
Wellington Grp LLC60,000$75.6K0.03%13F-HR/ATimeline
Cetera Investment Advisers59,163$74.5K<0.01%+11213F-HRTimeline
MERCER GLOBAL ADVISORS INC /ADV59,026$74.4K<0.01%-18,86013F-HRTimeline
Kestra Advisory Services, LLCgroup of 2 filers holding58,450$73.6K-38,807Timeline
Creative Planningin group Creative Planning58,061$73.2K<0.01%-22,73513F-HRTimelineGroup
Private Advisor Group, LLC55,301$69.7K<0.01%013F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…55,140$69.5K<0.01%013F-HRTimeline
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co54,068$68K<0.01%013F-HRTimelineGroup
SG Americas Securities, LLC54,022$68K<0.01%-32,99513F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS52,815$66.5K<0.01%-28,71013F-HRTimeline
TRANSCEND CAPITAL ADVISORS, LLC52,741$66.5K0.01%+17613F-HRTimeline
FIRST MANHATTAN CO. LLC.51,750$65.2K<0.01%013F-HRTimeline
Verition Fund Management LLC50,650$63.8K<0.01%-28,88413F-HRTimeline
Farmers National Bank50,300$63.4K0.01%013F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC45,025$56.7K<0.01%+3,72113F-HRTimeline
Mariner, LLCin group Mariner, LLC42,225$53.3K<0.01%-26,78113F-HRTimelineGroup
RK Asset Management, LLC40,485$51K0.05%013F-HRTimeline
CAPTRUST FINANCIAL ADVISORS40,120$50.6K<0.01%-27,90613F-HRTimeline
HOLLENCREST CAPITAL MANAGEMENT40,000$50.4K<0.01%-50,00013F-HRTimeline
Caitong International Asset Management …39,232$49.4K0.01%+35,84113F-HR/ATimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC38,744$48.8K<0.01%-23,46113F-HRTimelineGroup
HighTower Advisors, LLC37,453$47.2K<0.01%-2,95413F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…37,000$46.6K<0.01%-20,05013F-HRTimelineGroup
CHOREO, LLC33,757$43.9K<0.01%013F-HRTimeline
Waverly Advisors, LLC34,727$43.8K<0.01%new13F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…34,690$43.7K<0.01%013F-HRTimelineGroup
XPONANCE LLC32,361$40.8K<0.01%+19113F-HRTimeline
CIBC Bancorp USA Inc.group of 2 filers holding32,225$40.6KnewTimeline
Operose Advisors LLC32,000$40.3K0.01%013F-HRTimeline
DIVERSIFY WEALTH MANAGEMENT, LLCin group Diversify Advisory Services, …30,000$40.2K<0.01%013F-HRTimelineGroup
STRS OHIO31,900$40.2K<0.01%013F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…31,889$40.2K<0.01%013F-HRTimelineGroup
Fisher Asset Management, LLC30,000$37.8K<0.01%013F-HRTimeline
Orion Porfolio Solutions, LLC30,000$37.8K<0.01%-9613F-HRTimeline
IPG Investment Advisors LLC30,000$37.8K0.01%013F-HRTimeline
EP Wealth Advisors, LLC29,446$37.1K<0.01%13F-HRTimeline
Atom Investors LP28,258$35.6K<0.01%-13,61413F-HRTimeline
MACKENZIE FINANCIAL CORP25,843$33.5K<0.01%013F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD26,437$33.3K<0.01%-12,66013F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC26,366$33.2K<0.01%-28,40613F-HRTimelineGroup
CIM INVESTMENT MANAGEMENT INC25,804$32.5K0.01%013F-HRTimeline
SlateStone Wealth, LLC25,770$32K<0.01%013F-HRTimeline
Arrow Financial Corpin group Arrow Financial Corp25,000$31.5K<0.01%013F-HRTimelineGroup
Sterling Capital Management LLC23,720$29.9K<0.01%-4,67613F-HRTimeline
LPL Financial LLC22,458$28.3K<0.01%-8,47713F-HRTimeline
CIBC Asset Management Inc21,918$27.6K<0.01%013F-HRTimeline
StoneX Group Inc.in group StoneX Group Inc.21,599$27.2K<0.01%new13F-HRTimelineGroup
ZACKS INVESTMENT MANAGEMENT21,322$26.9K<0.01%new13F-HRTimeline
SAX WEALTH ADVISORS, LLC20,298$25.6K<0.01%-8213F-HRTimeline
CAPITAL ADVISORS INC/OK370,000$25.3K<0.01%013F-HRTimeline
CUMBERLAND ADVISORS INC19,500$24.6K0.01%013F-HRTimeline
Swiss Life Asset Management Ltdin group Swiss Life Asset Management L…19,164$24.1K<0.01%013F-HRTimelineGroup
Westmount Partners, LLC18,550$23.4K0.01%+2,00013F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC17,752$22.4K<0.01%-10,98513F-HRTimelineGroup
Quantinno Capital Management LP17,716$22.3K<0.01%new13F-HRTimeline
Cerity Partners LLCin group Cerity Partners LLC17,382$21.9K<0.01%-17,18413F-HRTimelineGroup
CIBC WORLD MARKET INC.17,228$21.7K<0.01%-12,70013F-HRTimeline
SHUFRO ROSE & CO LLC17,000$21.4K<0.01%013F-HRTimeline
Caprock Group, LLC16,770$21.1K<0.01%013F-HRTimeline
CITIGROUP INCin group CITIGROUP INC16,542$20.8K<0.01%-16,20613F-HRTimelineGroup
COMMONS CAPITAL, LLC16,300$20.5K0.01%013F-HRTimeline
Sigma Planning Corp15,807$19.9K<0.01%013F-HRTimeline
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP15,358$19.4K<0.01%-1,50013F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC15,277$19.2K<0.01%new13F-HRTimelineGroup
Key Financial Inc15,250$19.2K<0.01%+4,25013F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …14,823$18.7K<0.01%013F-HRTimelineGroup
Sanctuary Advisors, LLC14,758$18.6K<0.01%-90913F-HRTimeline
Colony Family Offices, LLC14,729$18.6K<0.01%013F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP14,125$17.8K<0.01%013F-HRTimelineGroup
FMR LLCin group FMR LLC14,087$17.8K<0.01%-2,47713F-HRTimelineGroup
Formidable Asset Management, LLC11,296$17.5K<0.01%-3,00013F-HRTimeline
AMALGAMATED BANK12,929$16K<0.01%+1,81913F-HRTimeline
Mill Creek Capital Advisors, LLC12,383$15.6K<0.01%013F-HRTimeline
TRAPHAGEN INVESTMENT ADVISORS LLC11,680$14.7K<0.01%013F-HRTimeline
Focus Partners Wealthgroup of 2 filers holding11,664$14.7K-22,042Timeline
Compound Planning, Inc.11,500$14.5K<0.01%new13F-HRTimeline
HBK Sorce Advisory LLC11,057$13.7K<0.01%-2,47013F-HRTimeline
ExodusPoint Capital Management, LP10,637$13.4K<0.01%new13F-HRTimeline
DIVERSIFIED TRUST CO10,374$13.1K<0.01%013F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO10,163$12.8K<0.01%013F-HRTimelineGroup
KLCM Advisors, Inc.10,000$12.6K<0.01%013F-HRTimeline
MRP Capital Investments, LLC10,000$12.6K0.01%013F-HRTimeline
Greenbush Financial Group, LLC10,000$12.6K<0.01%013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…9,128$11.5K<0.01%-12,41513F-HRTimelineGroup
Aventura Private Wealth, LLC8,400$10.6K<0.01%013F-HRTimeline
Allworth Financial LP8,151$10.3K<0.01%+2,16613F-HRTimeline
Steward Partners Investment Advisory, L…7,110$8.96K<0.01%013F-HRTimeline
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …6,045$8K<0.01%+2,26813F-HRTimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/6,200$7.75K<0.01%013F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…5,625$7.09K<0.01%-1,16813F-HRTimelineGroup
Altshuler Shaham Ltd3,292$4.21K<0.01%+2,16013F-HRTimeline
GABLES CAPITAL MANAGEMENT INC.3,000$3.78K<0.01%013F-HRTimeline
Smartleaf Asset Management LLC2,757$3.58K<0.01%013F-HRTimeline
Essential Partners LLC1,716$2.16K<0.01%-3,66613F-HRTimeline
CoreCap Advisors, LLC1,600$2.02K<0.01%013F-HRTimeline
Aster Capital Management (DIFC) Ltd1,408$1.77K<0.01%-3,27213F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.1,393$1.75K<0.01%-1,36313F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC1,312$1.65K<0.01%-3,16013F-HRTimeline
Godfrey Financial Associates, Inc.1,250$1.57K<0.01%13F-HRTimeline
PFS Partners, LLC1,100$1.39K<0.01%013F-HRTimeline
Salomon & Ludwin, LLC921$1.18K<0.01%-3013F-HRTimeline
True Wealth Design, LLC872$1.1K<0.01%+613F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\500$630<0.01%-60013F-HRTimelineGroup
ROTHSCHILD INVESTMENT LLC449$566<0.01%-23013F-HRTimeline
IFP Advisors, Inc432$544<0.01%-17913F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…401$505<0.01%-1,00013F-HR/ATimelineGroup
PITTENGER & ANDERSON INC250$315<0.01%013F-HRTimeline
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…228$287<0.01%+113F-HR/ATimelineGroup