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Disclosery

OPK OPKO HEALTH INC

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COM (common), issuer CIK 944809

228 managers (233 13F filers) reported a position in OPK shares at 2025-09-30, 196,305,908 shares in all. 27 filers opened a position and 15 filers sold out during the quarter.

Managers
228
13F filers
233
New
27
Added
77
Reduced
53
Sold out
15
Shares held by filers
196,305,908

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Rubric Capital Management LP47,791,243$74.1M0.99%013F-HRTimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC37,535,897$58.2M<0.01%-702,81713F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.33,172,384$51.4M<0.01%+1,722,90213F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC10,993,345$17M<0.01%+568,87213F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP8,997,940$13.9M<0.01%+416,10013F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding5,449,101$8.45M-1,398,007Timeline
Whitefort Capital Management, LP4,900,000$7.59M2.51%+3,125,80013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co3,768,934$5.84M<0.01%+418,55813F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP3,657,846$5.67M<0.01%+175,57413F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC2,873,416$4.45M<0.01%+1,937,51613F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC2,386,535$3.7M<0.01%-433,52013F-HRTimelineGroup
AWM Investment Company, Inc.2,200,000$3.41M0.32%+200,00013F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP1,667,368$2.58M<0.01%-262,31513F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding1,599,744$2.48M-885,300Timeline
Y.D. More Investments Ltdin group Y.D. More Investments Ltd1,499,118$2.24M0.13%-29,78113F-HRTimelineGroup
WASHINGTON GROWTH STRATEGIES LLC1,356,124$2.1M1.5%013F-HRTimeline
PFG Investments, LLC1,337,375$2.07M0.11%+72,25013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/1,313,882$2.04M<0.01%-592,95713F-HR/ATimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp1,276,868$1.98M<0.01%+127,96213F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC1,218,002$1.89M<0.01%-101,55913F-HRTimelineGroup
Weiss Asset Management LPin group Weiss Asset Management LP1,130,771$1.75M0.03%-3,626,22113F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
Invesco Ltd.in group Invesco Ltd.1,017,561$1.58M<0.01%-353,48413F-HRTimelineGroup
Tejara Capital Ltd877,941$1.36M0.75%-68,14913F-HRTimeline
Swiss National Bank845,755$1.31M<0.01%+268,40013F-HRTimeline
Nuveen, LLCin group TIAA841,836$1.3M<0.01%-284,72113F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY837,601$1.3M<0.01%-1,221,45313F-HR/ATimelineGroup
Assenagon Asset Management S.A.690,200$1.03M<0.01%-244,90013F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC592,330$918K<0.01%+37,93213F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC587,753$911K<0.01%-76,65413F-HR/ATimelineGroup
RHUMBLINE ADVISERS555,382$861K<0.01%+25,82913F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO527,411$817K<0.01%-102,94413F-HR/ATimelineGroup
ALLIANCEBERNSTEIN L.P.475,190$737K<0.01%+6,90013F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…415,386$644K<0.01%+91,26913F-HRTimeline
Connor, Clark & Lunn Investment Managem…392,761$609K<0.01%+1,09713F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc386,837$598K<0.01%+31,15513F-HRTimelineGroup
GAMCO Investors (Gabelli)group of 2 filers holding345,000$535K0Timeline
PRICE T ROWE ASSOCIATES INC /MD/343,286$533K<0.01%-94,22013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN342,486$531K<0.01%+71,39213F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…297,835$462K<0.01%-346,83513F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC279,875$434K<0.01%+62,48013F-HRTimelineGroup
IEQ CAPITAL, LLC277,594$430K<0.01%+168,37513F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\275,188$427K<0.01%+36,17013F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA272,866$423K<0.01%+5,41813F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC262,838$407K<0.01%-1,121,71413F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL244,821$379K<0.01%013F-HR/ATimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …236,722$367K<0.01%+98,07913F-HRTimelineGroup
ZAZOVE ASSOCIATES LLC207,600$322K0.03%013F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…207,175$321K<0.01%-11,09713F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson206,314$319K<0.01%013F-HRTimelineGroup
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…191,186$296K<0.01%-6,96213F-HRTimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…176,260$273K<0.01%013F-HRTimeline
SIMPLEX TRADING, LLC150,566$233K0.01%new13F-HRTimeline
SIH Partners, LLLPin group SIH Partners, LLLP150,125$233K0.02%+80,70613F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC143,323$222K<0.01%+1,69913F-HRTimeline
Teton Advisors, LLC142,000$220K0.14%13F-HRTimeline
State of Wyoming135,954$211K0.02%+53,94713F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND130,901$203K<0.01%+70,10013F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM128,608$199K<0.01%+40,41413F-HRTimeline
CWM, LLCin group CWM, LLC124,774$193K<0.01%+102,18413F-HRTimelineGroup
TWO SIGMA SECURITIES, LLC121,094$188K0.03%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS118,309$183K<0.01%-463,36213F-HRTimelineGroup
Csenge Advisory Group117,001$181K0.01%+113F-HRTimeline
HIGHLINE WEALTH PARTNERS LLC116,681$181K0.05%+113F-HRTimeline
Humankind Investments LLC114,644$178K0.04%+5,34513F-HRTimeline
Glenmede Investment Management, LP113,413$176K<0.01%+66313F-HRTimeline
COMERICA BANK112,000$174K<0.01%013F-HRTimeline
VAN ECK ASSOCIATES CORPin group VAN ECK ASSOCIATES CORP111,826$173K<0.01%-7,21513F-HRTimelineGroup
Police & Firemen's Retirement System of…102,397$159K<0.01%+24,94813F-HRTimeline
Phoenix Financial Ltd.in group Phoenix Financial Ltd.100,000$156K<0.01%013F-HR/ATimelineGroup
RPg Family Wealth Advisory, LLC98,990$153K0.03%new13F-HRTimeline
Graham Capital Management, L.P.98,368$152K0.01%-1,812,76313F-HRTimeline
Kestra Advisory Services, LLCgroup of 2 filers holding97,257$151K0Timeline
Cambridge Investment Research Advisors,…96,511$150K<0.01%-6,60013F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC95,241$148K<0.01%+48113F-HRTimelineGroup
360 Financial, Inc.91,300$142K0.05%+2,50013F-HRTimeline
HOLLENCREST CAPITAL MANAGEMENT90,000$140K0.01%013F-HRTimeline
SG Americas Securities, LLC87,017$135K<0.01%-119,35813F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS81,525$126K<0.01%+30,24813F-HRTimeline
Creative Planningin group Creative Planning80,796$125K<0.01%+56,30413F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.86,775$124K<0.01%-7,70113F-HRTimelineGroup
Verition Fund Management LLC79,534$123K<0.01%+28,88413F-HRTimeline
MERCER GLOBAL ADVISORS INC /ADV77,886$121K<0.01%+38,35213F-HRTimeline
WEALTH ENHANCEMENT ADVISORY SERVICES, L…75,749$117K<0.01%+38,75513F-HRTimeline
KLP KAPITALFORVALTNING AS74,000$115K<0.01%013F-HRTimeline
Cubist Systematic Strategies, LLC72,127$112K<0.01%-61,53213F-HRTimeline
ProShare Advisors LLC70,369$109K<0.01%-3,81513F-HRTimeline
Mariner, LLCin group Mariner, LLC69,006$107K<0.01%+44,91413F-HRTimelineGroup
CAPTRUST FINANCIAL ADVISORS68,026$105K<0.01%+26,09913F-HRTimeline
Cascade Financial Partners, LLC66,490$103K0.01%013F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…65,495$102K<0.01%013F-HRTimelineGroup
Arax Advisory Partners63,780$98.9K<0.01%new13F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC62,205$96.4K<0.01%-3,96513F-HRTimelineGroup
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…61,502$95K<0.01%013F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC59,700$92.5K<0.01%+21,60013F-HRTimeline
BRIGHTON JONES LLC59,426$92.1K<0.01%+20,51013F-HRTimeline
Cetera Investment Advisers59,051$91.5K<0.01%-1,50613F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…57,050$88.4K<0.01%+25013F-HRTimelineGroup
Private Advisor Group, LLC55,301$85.7K<0.01%013F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…55,140$85.5K<0.01%013F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC54,772$84.9K<0.01%+7,93013F-HRTimelineGroup
TRANSCEND CAPITAL ADVISORS, LLC52,565$81.5K0.01%+1,71413F-HRTimeline
FIRST MANHATTAN CO. LLC.51,750$80.2K<0.01%013F-HRTimeline
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co54,068$79K<0.01%013F-HRTimelineGroup
Farmers National Bank50,300$78K0.02%013F-HRTimeline
Headlands Technologies LLC45,240$70.1K0.01%-12,48413F-HRTimeline
CIBC Bancorp USA Inc.in group CIBC Bancorp USA Inc.43,868$68K<0.01%13F-HR/ATimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC42,519$65.9K<0.01%-49,91513F-HRTimelineGroup
Atom Investors LP41,872$64.9K<0.01%-1,41013F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC41,304$64K<0.01%-45713F-HRTimeline
RK Asset Management, LLC40,485$63K0.06%013F-HRTimeline
World Investment Advisors40,618$63K<0.01%013F-HRTimeline
HighTower Advisors, LLC40,407$62.6K<0.01%+1,50113F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD39,097$60.6K<0.01%+17,90413F-HRTimeline
EntryPoint Capital, LLC38,828$60.2K0.02%new13F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…34,690$53.8K<0.01%+34,07013F-HRTimelineGroup
Cerity Partners LLCin group Cerity Partners LLC34,566$53.6K<0.01%new13F-HRTimelineGroup
CHOREO, LLC33,757$52.3K<0.01%013F-HRTimeline
CITIGROUP INCin group CITIGROUP INC32,748$50.8K<0.01%-134,36313F-HRTimelineGroup
Focus Partners Wealthgroup of 2 filers holding33,706$50.1KnewTimeline
XPONANCE LLC32,170$49.9K<0.01%+4,22113F-HRTimeline
NORRIS PERNE & FRENCH LLP/MI32,000$49.6K<0.01%013F-HRTimeline
Operose Advisors LLC32,000$49.6K0.01%013F-HRTimeline
STRS OHIO31,900$49.4K<0.01%013F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…31,889$49.4K<0.01%013F-HRTimelineGroup
LPL Financial LLC30,935$47.9K<0.01%+10,69913F-HRTimeline
Orion Porfolio Solutions, LLC30,096$46.6K<0.01%+9613F-HRTimeline
Fisher Asset Management, LLC30,000$46.5K<0.01%-30113F-HRTimeline
IPG Investment Advisors LLC30,000$46.5K0.01%013F-HRTimeline
CIBC WORLD MARKET INC.29,928$46.4K<0.01%013F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC28,737$44.5K<0.01%+3,96413F-HRTimelineGroup
Sterling Capital Management LLC28,396$44K<0.01%+18,62813F-HRTimeline
DIVERSIFY WEALTH MANAGEMENT, LLCin group Diversify Advisory Services, …30,000$42K<0.01%013F-HRTimelineGroup
PBMares Wealth Management LLC27,021$41.9K0.01%013F-HRTimeline
MACKENZIE FINANCIAL CORP25,843$40.1K<0.01%013F-HRTimeline
SlateStone Wealth, LLC25,770$40K<0.01%013F-HRTimeline
CIM INVESTMENT MANAGEMENT INC25,804$40K0.01%-27,78713F-HRTimeline
MOSELEY INVESTMENT MANAGEMENT INC25,153$39K0.01%+1,00013F-HRTimeline
Arrow Financial Corpin group Arrow Financial Corp25,000$38.8K<0.01%new13F-HRTimelineGroup
CAPITAL ADVISORS INC/OK370,000$36.6K<0.01%013F-HRTimeline
CIBC Asset Management Inc21,918$34K<0.01%013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…21,543$33.4K<0.01%-9,17013F-HRTimelineGroup
X-Square Capital, LLC20,933$32K0.01%-10713F-HRTimeline
SAX WEALTH ADVISORS, LLC20,380$31.6K<0.01%+22013F-HRTimeline
Sovereign Financial Group, Inc.20,078$31.1K0.01%013F-HRTimeline
CUMBERLAND ADVISORS INC19,500$30.2K0.01%013F-HRTimeline
Swiss Life Asset Management Ltdin group Swiss Life Asset Management L…19,164$29.7K<0.01%new13F-HRTimelineGroup
SHUFRO ROSE & CO LLC17,000$28.2K<0.01%013F-HRTimeline
Integrated Wealth Concepts LLC17,698$27.4K<0.01%+3,37613F-HRTimeline
Equitable Holdings, Inc.in group Equitable Holdings, Inc.17,056$26.4K<0.01%-11,87513F-HRTimelineGroup
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP16,858$26.1K<0.01%+16913F-HRTimelineGroup
SHELL ASSET MANAGEMENT CO16,596$26K<0.01%-20,43213F-HRTimeline
FMR LLCin group FMR LLC16,564$25.7K<0.01%+44313F-HRTimelineGroup
Westmount Partners, LLC16,550$25.7K0.01%013F-HRTimeline
COMMONS CAPITAL, LLC16,300$25.3K0.02%013F-HRTimeline
Sigma Planning Corp15,807$24.5K<0.01%-2,16513F-HRTimeline
Sanctuary Advisors, LLC15,667$24.3K<0.01%+1,62713F-HR/ATimeline
Kovack Advisors, Inc.15,000$23.2K<0.01%013F-HRTimeline
Caprock Group, LLC16,770$23.1K<0.01%13F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …14,823$23K<0.01%new13F-HRTimelineGroup
Colony Family Offices, LLC14,729$22.8K0.01%013F-HRTimeline
MML INVESTORS SERVICES, LLC14,026$21.7K<0.01%new13F-HRTimeline
Merit Financial Group, LLC13,585$21.1K<0.01%new13F-HR/ATimeline
HBK Sorce Advisory LLC13,527$20.6K<0.01%+2,47013F-HR/ATimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP14,125$20.5K<0.01%+85013F-HRTimelineGroup
NorthCrest Asset Manangement, LLC12,470$19.2K<0.01%new13F-HRTimeline
Mill Creek Capital Advisors, LLC12,383$19.2K<0.01%013F-HRTimeline
Formidable Asset Management, LLC14,296$18.9K<0.01%-75013F-HRTimeline
Pallas Capital Advisors LLC11,710$18.2K<0.01%new13F-HRTimeline
TRAPHAGEN INVESTMENT ADVISORS LLC11,680$18.1K<0.01%013F-HRTimeline
Point72 (DIFC) Ltd11,450$17.7K<0.01%new13F-HRTimeline
Stillwater Capital Advisors, LLC11,380$17.6K<0.01%013F-HRTimeline
Key Financial Inc11,000$17.1K<0.01%013F-HRTimeline
AMALGAMATED BANK11,110$17K<0.01%013F-HRTimeline
DIVERSIFIED TRUST CO10,374$16.1K<0.01%+37413F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO10,163$15.8K<0.01%013F-HRTimelineGroup
KLCM Advisors, Inc.10,000$15.5K<0.01%013F-HRTimeline
Capital Square, LLC10,000$15.5K0.01%-1,00013F-HRTimeline
Simplicity Wealth,LLC10,000$15.5K<0.01%013F-HRTimeline
Greenbush Financial Group, LLC10,000$15.5K0.01%013F-HRTimeline
Point72 Asia (Singapore) Pte. Ltd.9,624$14.9K<0.01%new13F-HRTimeline
Krilogy Financial LLC10,910$14.6K<0.01%new13F-HRTimeline
MRP Capital Investments, LLC10,000$13.2K0.01%013F-HR/ATimeline
Aventura Private Wealth, LLC8,400$13K<0.01%013F-HRTimeline
Steward Partners Investment Advisory, L…7,110$11K<0.01%-3013F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…6,793$10.5K<0.01%+4,11613F-HRTimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/6,200$9.55K<0.01%+1,27813F-HRTimelineGroup
Allworth Financial LP5,985$9.28K<0.01%+4,17213F-HRTimeline
Essential Partners LLC5,382$8.34K<0.01%+4,35813F-HRTimeline
Aster Capital Management (DIFC) Ltd4,680$7.25K<0.01%+1,22713F-HRTimeline
NISA INVESTMENT ADVISORS, LLC4,472$6.93K<0.01%+16913F-HRTimeline
FSA Wealth Management LLC3,950$6.12K<0.01%013F-HRTimeline
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …3,777$6K<0.01%013F-HRTimelineGroup
Wealthspire Advisors, LLC3,700$5.74K<0.01%new13F-HRTimeline
Caitong International Asset Management …3,391$5.26K<0.01%new13F-HRTimeline
GABLES CAPITAL MANAGEMENT INC.3,000$4.65K<0.01%013F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.2,756$4.27K<0.01%new13F-HRTimelineGroup
Smartleaf Asset Management LLC2,757$4.05K<0.01%+2,28313F-HRTimeline
CoreCap Advisors, LLC1,600$2.48K<0.01%013F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…1,401$2.17K<0.01%new13F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\1,100$1.71K<0.01%+50013F-HRTimelineGroup