Skip to content
Disclosery

OPK OPKO HEALTH INC

Follow

COM (common), issuer CIK 944809

219 managers (223 13F filers) reported a position in OPK shares at 2025-06-30, 205,191,598 shares in all. 13 filers opened a position and 48 filers sold out during the quarter.

Managers
219
13F filers
223
New
13
Added
56
Reduced
66
Sold out
48
Shares held by filers
205,191,598

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2025

Filers in the available 13F reports with a share position at 2025-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Rubric Capital Management LP47,791,243$63.1M1.01%-915,39713F-HRTimeline
VANGUARD GROUP INCin group VANGUARD GROUP INC38,238,714$50.5M<0.01%+8,738,64313F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.31,449,482$41.5M<0.01%+3,844,50813F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC10,424,473$13.8M<0.01%+1,995,63313F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP8,581,840$11.3M<0.01%+442,34413F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding6,847,108$9.04M+3,648,421Timeline
Weiss Asset Management LPin group Weiss Asset Management LP4,756,992$6.28M0.1%-6,435,80813F-HRTimelineGroupThe filing omitted confidential holdings, a later amendment may add them.
NORTHERN TRUST CORPin group NORTHERN TRUST CORP3,482,272$4.6M<0.01%-47,12013F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co3,350,376$4.42M<0.01%+608,39013F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP3,348,166$4.42M0.01%-1,548,26213F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC2,820,055$3.72M<0.01%-1,181,15913F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding2,485,044$3.28M+287,572Timeline
MORGAN STANLEYin group MORGAN STANLEY2,059,054$2.72M<0.01%-2,049,43413F-HRTimelineGroup
AWM Investment Company, Inc.2,000,000$2.64M0.3%+150,00013F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP1,929,683$2.55M<0.01%-292,82913F-HRTimelineGroup
Graham Capital Management, L.P.1,911,131$2.52M0.08%+100,73913F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/1,906,839$2.52M<0.01%-2,252,04313F-HRTimelineGroup
Whitefort Capital Management, LP1,774,200$2.34M0.91%new13F-HR/ATimeline
Y.D. More Investments Ltdin group Y.D. More Investments Ltd1,528,899$2.01M0.14%-244,04813F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC1,384,552$1.83M<0.01%+835,21413F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.1,371,045$1.81M<0.01%-252,55513F-HRTimelineGroup
WASHINGTON GROWTH STRATEGIES LLC1,356,124$1.79M1.37%+1,356,12213F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC1,319,561$1.74M<0.01%+509,68513F-HRTimelineGroup
PFG Investments, LLC1,265,125$1.67M0.1%+47,76513F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp1,148,906$1.52M<0.01%+128,38513F-HRTimelineGroup
Nuveen, LLCin group TIAA1,126,557$1.49M<0.01%-250,32413F-HRTimelineGroup
Tejara Capital Ltd946,090$1.25M0.58%+85,74613F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC935,900$1.24M<0.01%-673,00613F-HRTimelineGroup
Assenagon Asset Management S.A.935,100$1.23M<0.01%013F-HRTimeline
Clearstead Advisors, LLC883,042$1.17M0.02%013F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC695,780$918K<0.01%-5,691,13113F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC664,407$877K<0.01%+272,41613F-HR/ATimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…644,670$851K<0.01%-111,47613F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO630,355$832K<0.01%-1,870,97713F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS581,671$768K<0.01%-309,47413F-HRTimelineGroup
Swiss National Bank577,355$762K<0.01%-83,80013F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC554,398$732K<0.01%+74,56813F-HRTimeline
RHUMBLINE ADVISERS529,553$699K<0.01%+39,27413F-HRTimeline
ALLIANCEBERNSTEIN L.P.468,290$618K<0.01%-36,10013F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/437,506$578K<0.01%-64,16213F-HRTimeline
Connor, Clark & Lunn Investment Managem…391,664$517K<0.01%+190,31913F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc355,682$469K<0.01%+5,58413F-HRTimelineGroup
GAMCO Investors (Gabelli)group of 2 filers holding345,000$455K0Timeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…324,117$428K<0.01%013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN271,094$358K<0.01%+41,07913F-HRTimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA267,448$352K<0.01%+30,83913F-HR/ATimelineGroup
TUDOR INVESTMENT CORP ET AL244,821$323K<0.01%013F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\239,018$316K<0.01%-42,62913F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…218,272$288K<0.01%+54,04213F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC217,395$287K<0.01%-1,639,13113F-HRTimelineGroup
ZAZOVE ASSOCIATES LLC207,600$274K0.02%013F-HR/ATimeline
SG Americas Securities, LLC206,375$272K<0.01%-145,90113F-HRTimeline
JANUS HENDERSON GROUP PLCin group Janus Henderson206,314$271K<0.01%013F-HRTimelineGroup
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…198,148$262K<0.01%+8,95413F-HRTimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…176,260$233K<0.01%013F-HRTimeline
CITIGROUP INCin group CITIGROUP INC167,111$221K<0.01%-96,79013F-HRTimelineGroup
Teton Advisors, Inc.142,000$187K0.11%-2,50013F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC141,624$187K<0.01%-62,69313F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …138,643$183K<0.01%+13,91213F-HRTimelineGroup
Cubist Systematic Strategies, LLC133,659$176K<0.01%+14,43613F-HRTimeline
Csenge Advisory Group117,000$159K0.01%013F-HRTimeline
VAN ECK ASSOCIATES CORPin group VAN ECK ASSOCIATES CORP119,041$157K<0.01%+5,53513F-HRTimelineGroup
HIGHLINE WEALTH PARTNERS LLC116,680$154K0.05%013F-HRTimeline
Glenmede Investment Management, LP112,750$149K<0.01%13F-HRTimeline
COMERICA BANK112,000$148K<0.01%013F-HRTimeline
Humankind Investments LLC109,299$144K0.04%+62,88613F-HRTimeline
IEQ CAPITAL, LLC109,219$144K<0.01%-74,14413F-HRTimeline
Cambridge Investment Research Advisors,…103,111$136K<0.01%+113F-HRTimeline
Phoenix Financial Ltd.in group Phoenix Financial Ltd.100,000$133K<0.01%013F-HRTimelineGroup
INTREPID CAPITAL MANAGEMENT INC100,000$132K0.05%013F-HRTimeline
Kestra Advisory Services, LLCgroup of 2 filers holding97,257$128K-11,500Timeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC94,760$125K<0.01%+66913F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.94,476$125K<0.01%-557,33313F-HR/ATimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC92,434$122K<0.01%-209,42713F-HR/ATimelineGroup
HOLLENCREST CAPITAL MANAGEMENT90,000$119K0.01%013F-HRTimeline
360 Financial, Inc.88,800$117K0.04%+9,50013F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM88,194$116K<0.01%-9,68913F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd84,907$112K<0.01%-224,38313F-HRTimelineGroup
State of Wyoming82,007$108K0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…77,449$102K<0.01%013F-HRTimeline
ProShare Advisors LLC74,184$97.9K<0.01%+5,13913F-HRTimeline
KLP KAPITALFORVALTNING AS74,000$97.7K<0.01%013F-HRTimeline
SIH Partners, LLLPin group SIH Partners, LLLP69,419$91.6K0.01%new13F-HRTimelineGroup
Cascade Financial Partners, LLC66,490$87.8K0.01%013F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC66,170$87.3K<0.01%-19,20013F-HRTimelineGroup
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…65,495$86.5K<0.01%013F-HRTimelineGroup
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…61,502$81K<0.01%013F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND60,801$80.3K<0.01%013F-HR/ATimeline
Cetera Investment Advisers60,557$79.9K<0.01%+113F-HRTimeline
Headlands Technologies LLC57,724$76.2K0.01%+5,57513F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…56,800$75K<0.01%013F-HRTimelineGroup
CIM INVESTMENT MANAGEMENT INC53,591$74.8K0.01%+26,89413F-HRTimeline
Private Advisor Group, LLC55,301$73K<0.01%013F-HRTimeline
Zurcher Kantonalbank (Zurich Cantonalba…55,140$72.8K<0.01%013F-HRTimeline
Engineers Gate Manager LP55,124$72.8K<0.01%-161,23313F-HRTimeline
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co54,068$71K<0.01%013F-HRTimelineGroup
FIRST MANHATTAN CO. LLC.51,750$68.3K<0.01%013F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS51,277$67.7K<0.01%-32,48913F-HRTimeline
TRANSCEND CAPITAL ADVISORS, LLC50,851$67.1K0.01%+113F-HRTimeline
Verition Fund Management LLC50,650$66.9K<0.01%-267,29613F-HRTimeline
Farmers National Bank50,300$66.4K0.02%013F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC46,842$61.8K<0.01%+20,07613F-HRTimelineGroup
CIBC WORLD MARKETS CORP44,575$58.8K<0.01%-26,19413F-HRTimeline
Atom Investors LP43,282$57.1K0.01%+2,52213F-HRTimeline
CAPTRUST FINANCIAL ADVISORS41,927$55.3K<0.01%-6,55513F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC41,761$55.1K<0.01%+5,14513F-HRTimeline
World Investment Advisors40,618$53.6K<0.01%013F-HRTimeline
RK Asset Management, LLC40,485$53K0.05%013F-HRTimeline
MERCER GLOBAL ADVISORS INC /ADV39,534$52.2K<0.01%-15,42313F-HRTimeline
NORGES BANK39,477$52.1K<0.01%-454,78013F-HRTimeline
BRIGHTON JONES LLC38,916$51.4K<0.01%+8,77513F-HRTimeline
HighTower Advisors, LLC38,906$51.4K<0.01%013F-HRTimeline
WEALTH ENHANCEMENT ADVISORY SERVICES, L…36,994$50.3K<0.01%-37,71213F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC38,100$50.3K<0.01%new13F-HRTimeline
SHELL ASSET MANAGEMENT CO37,028$49K<0.01%-3,96913F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC34,939$46.3K<0.01%-1,91313F-HRTimelineGroup
CHOREO, LLC33,757$44.6K<0.01%013F-HRTimeline
NORRIS PERNE & FRENCH LLP/MI32,000$42.2K<0.01%013F-HRTimeline
Operose Advisors LLC32,000$42.2K0.01%013F-HRTimeline
STRS OHIO31,900$42.1K<0.01%013F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…31,889$42.1K<0.01%013F-HRTimelineGroup
Kapitalo Investimentos Ltda31,347$41.4K0.01%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…30,713$40.5K<0.01%-11,73713F-HRTimelineGroup
Fisher Asset Management, LLC30,301$40K<0.01%new13F-HRTimeline
Orion Porfolio Solutions, LLC30,000$39.6K<0.01%013F-HR/ATimeline
IPG Investment Advisors LLC30,000$39.6K0.01%013F-HRTimeline
DIVERSIFY WEALTH MANAGEMENT, LLCin group Diversify Advisory Services, …30,000$39.6K<0.01%013F-HRTimelineGroup
CIBC WORLD MARKET INC.29,928$39.5K<0.01%013F-HRTimeline
CAPITAL ADVISORS INC/OK370,000$38.4K<0.01%+20,00013F-HRTimeline
Equitable Holdings, Inc.in group Equitable Holdings, Inc.28,931$38.2K<0.01%013F-HRTimelineGroup
EP Wealth Advisors, LLC28,900$38.1K<0.01%-33813F-HRTimeline
XPONANCE LLC27,949$36.9K<0.01%+4,19113F-HRTimeline
PBMares Wealth Management LLC27,021$35.7K0.01%013F-HRTimeline
MACKENZIE FINANCIAL CORP25,843$34.1K<0.01%013F-HRTimeline
SlateStone Wealth, LLC25,770$34K<0.01%013F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC24,773$32.7K<0.01%+3,64813F-HRTimelineGroup
Creative Planningin group Creative Planning24,492$32.3K<0.01%-3,60513F-HRTimelineGroup
MOSELEY INVESTMENT MANAGEMENT INC24,153$31.9K0.01%013F-HRTimeline
Mariner, LLCin group Mariner, LLC24,092$31.8K<0.01%+6,62913F-HRTimelineGroup
CWM, LLCin group CWM, LLC22,590$30K<0.01%-51,91313F-HRTimelineGroup
Altshuler Shaham Ltd22,471$29.6K<0.01%-1,431,75013F-HRTimeline
CIBC Asset Management Inc21,918$28.9K<0.01%013F-HRTimeline
SHUFRO ROSE & CO LLC17,000$28.2K<0.01%013F-HRTimeline
X-Square Capital, LLC21,040$28K0.01%-439,38513F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD21,193$28K<0.01%-8,57713F-HRTimeline
LPL Financial LLC20,236$26.7K<0.01%-9713F-HRTimeline
SAX WEALTH ADVISORS, LLC20,160$26.6K<0.01%+5013F-HRTimeline
Sovereign Financial Group, Inc.20,078$26.5K0.01%-613F-HRTimeline
CUMBERLAND ADVISORS INC19,500$25.7K0.01%013F-HRTimeline
Formidable Asset Management, LLC15,046$25K<0.01%013F-HRTimeline
Sigma Planning Corp17,972$23.7K<0.01%013F-HRTimeline
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP16,689$22K<0.01%-16013F-HRTimelineGroup
Westmount Partners, LLC16,550$21.8K0.01%013F-HRTimeline
COMMONS CAPITAL, LLC16,300$21.5K0.02%013F-HRTimeline
FMR LLCin group FMR LLC16,121$21.3K<0.01%-8,26713F-HRTimelineGroup
Kovack Advisors, Inc.15,000$19.8K<0.01%+5,00013F-HRTimeline
Colony Family Offices, LLC14,729$19.4K0.01%013F-HRTimeline
Integrated Wealth Concepts LLC14,322$18.9K<0.01%new13F-HRTimeline
Sanctuary Advisors, LLC14,040$18.5K<0.01%-15113F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP13,275$17.5K<0.01%+1,65013F-HRTimelineGroup
Mill Creek Capital Advisors, LLC12,383$16.3K<0.01%new13F-HRTimeline
Farther Finance Advisors, LLC12,219$16.1K<0.01%013F-HRTimeline
Janney Montgomery Scott LLC12,500$16K<0.01%new13F-HRTimeline
TRAPHAGEN INVESTMENT ADVISORS LLC11,680$15.4K<0.01%013F-HRTimeline
Stillwater Capital Advisors, LLC11,380$15K<0.01%013F-HRTimeline
AMALGAMATED BANK11,110$15K<0.01%013F-HRTimeline
Capital Square, LLC11,000$14.8K0.01%013F-HRTimeline
HBK Sorce Advisory LLC11,057$14.6K<0.01%-35213F-HRTimeline
Key Financial Inc11,000$14.5K<0.01%013F-HRTimeline
SEI INVESTMENTS COin group SEI INVESTMENTS CO10,163$13.4K<0.01%013F-HRTimelineGroup
KLCM Advisors, Inc.10,000$13.2K<0.01%013F-HRTimeline
DIVERSIFIED TRUST CO10,000$13.2K<0.01%-91413F-HRTimeline
Simplicity Wealth,LLC10,000$13.2K<0.01%new13F-HRTimeline
MRP Capital Investments, LLC10,000$13.2K0.01%013F-HRTimeline
Greenbush Financial Group, LLC10,000$13.2K0.01%013F-HRTimeline
Sterling Capital Management LLC9,768$12.9K<0.01%+4,26513F-HR/ATimeline
Aventura Private Wealth, LLC8,400$11.1K<0.01%013F-HRTimeline
Steward Partners Investment Advisory, L…7,140$9.43K<0.01%-3,09413F-HRTimeline
Raiffeisen Bank International AGin group Raiffeisen Bank International…6,521$8.61K<0.01%013F-HRTimelineGroup
NATIONAL BANK OF CANADA /FI/in group NATIONAL BANK OF CANADA /FI/4,922$6.43K<0.01%-67513F-HR/ATimelineGroup
NISA INVESTMENT ADVISORS, LLC4,303$5.68K<0.01%-16013F-HRTimeline
FSA Wealth Management LLC3,950$5.21K<0.01%013F-HRTimeline
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …3,777$5K<0.01%new13F-HRTimelineGroup
Aster Capital Management (DIFC) Ltd3,453$4.56K<0.01%-15,80913F-HRTimeline
Larson Financial Group LLC3,040$4.01K<0.01%+3,00013F-HRTimeline
GABLES CAPITAL MANAGEMENT INC.3,000$3.96K<0.01%013F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…2,677$3.53K<0.01%+39713F-HRTimelineGroup
Moser Wealth Advisors, LLC2,392$3.16K<0.01%013F-HRTimeline
Allworth Financial LP1,813$2.39K<0.01%+19013F-HRTimeline
CoreCap Advisors, LLC1,600$2.11K<0.01%-13413F-HRTimeline
PFS Partners, LLC1,100$1.45K<0.01%013F-HRTimeline
Essential Partners LLC1,024$1.35K<0.01%13F-HRTimeline
MAI Capital Management1,000$1.32K<0.01%013F-HRTimeline
Salomon & Ludwin, LLC976$1.31K<0.01%-1913F-HRTimeline
Transce3nd, LLC900$1.19K<0.01%013F-HRTimeline
CBIZ Investment Advisory Services, LLC698$921<0.01%013F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…620$818<0.01%013F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\600$792<0.01%-82813F-HRTimelineGroup
Smartleaf Asset Management LLC474$625<0.01%013F-HRTimeline
Physician Wealth Advisors, Inc.470$621<0.01%new13F-HRTimeline