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TWO SIGMA INVESTMENTS, LP: OPK position timeline

Available 13F reports, 13D and 13G stakes and each Form 3, 4 and 5 line of TWO SIGMA INVESTMENTS, LP on OPK, newest first. How the timeline and the estimate are built.

TWO SIGMA INVESTMENTS, LP held 175,801 OPK shares at 2026-06-30 per its 13F-HR filed 2026-08-14.

the latest 13F is the newest step

  1. period ended2026-06-30
    13F 175,801 shares
    Change vs previous 13F +5,801 shares

    <0.01% of the 13F portfolio, value $263,702.

    13F-HR 0000899140-26-000855 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  2. period ended2026-03-31
    13F 170,000 shares
    Share basis changed not comparable

    Membership change: TWO SIGMA ADVISERS, LP left the group. <0.01% of the 13F portfolio, value $193,800.

    13F-HR 0000899140-26-000547 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  3. period ended2025-12-31
    13F 925,948 shares
    Change vs previous 13F -673,796 shares

    <0.01% of the 13F portfolio, value $1,166,694.

    13F-HR 0000899140-26-000232 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 734,747 shares
    • TWO SIGMA ADVISERS, LP: 191,201 shares

    Acceptance time not in the bulk data set (spec §4.2).

  4. period ended2025-09-30
    13F 1,599,744 shares
    Change vs previous 13F -885,300 shares

    <0.01% of the 13F portfolio, value $2,479,603.

    13F-HR 0000899140-25-001286 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 1,255,647 shares
    • TWO SIGMA ADVISERS, LP: 344,097 shares

    Acceptance time not in the bulk data set (spec §4.2).

  5. period ended2025-06-30
    13F 2,485,044 shares
    Change vs previous 13F +287,572 shares

    <0.01% of the 13F portfolio, value $3,280,258.

    13F-HR 0000899140-25-000964 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 1,836,747 shares
    • TWO SIGMA ADVISERS, LP: 648,297 shares

    Acceptance time not in the bulk data set (spec §4.2).

  6. period ended2025-03-31
    13F 2,197,472 shares
    Change vs previous 13F +168,708 shares

    <0.01% of the 13F portfolio, value $3,647,803.

    13F-HR 0000899140-25-000680 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 1,645,775 shares
    • TWO SIGMA ADVISERS, LP: 551,697 shares

    Acceptance time not in the bulk data set (spec §4.2).

  7. period ended2024-12-31
    13F 2,028,764 shares
    Change vs previous 13F +958,067 shares

    <0.01% of the 13F portfolio, value $2,982,283.

    13F-HR 0000899140-25-000265 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 1,647,567 shares
    • TWO SIGMA ADVISERS, LP: 381,197 shares

    Acceptance time not in the bulk data set (spec §4.2).

  8. period ended2024-09-30
    13F 1,070,697 shares
    Change vs previous 13F not available

    <0.01% of the 13F portfolio, value $1,595,338.

    13F-HR 0000919574-24-006611 filed by TWO SIGMA INVESTMENTS, LP
    Filed (acceptance time not in the bulk data set), ingested

    • TWO SIGMA INVESTMENTS, LP: 697,896 shares
    • TWO SIGMA ADVISERS, LP: 372,801 shares

    Acceptance time not in the bulk data set (spec §4.2).