SAMSARA BIOCAPITAL, LLC More: the full row for SAMSARA BIOCAPITAL, LLC 5,194,805 $28.8M 2.8% 0 13F-HR Timeline Caligan Partners LP More: the full row for Caligan Partners LP 4,974,906 $27.6M 1.95% +2,974,906 13F-HR Timeline Paradigm Biocapital Advisors LP in group Paradigm Biocapital Advisors … More: the full row for Paradigm Biocapital Advisors LP 4,000,000 $22.2M 0.45% 0 13F-HR Timeline Group MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 2,987,613 $16.6M 0.01% +335,043 13F-HR Timeline Group Trails Edge Capital Partners, LP More: the full row for Trails Edge Capital Partners, LP 2,657,997 $14.8M 3.47% 0 13F-HR Timeline FRANKLIN RESOURCES INC in group Franklin Resources More: the full row for FRANKLIN RESOURCES INC 2,461,565 $13.7M <0.01% -38,576 13F-HR Timeline Group SymBiosis Capital Partners, LLC More: the full row for SymBiosis Capital Partners, LLC 2,354,000 $13.1M 24.76% -246,000 13F-HR Timeline UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 2,318,693 $12.9M <0.01% -325,009 13F-HR Timeline Group ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 2,174,398 $12.1M 0.73% -535,448 13F-HR Timeline Group Polar Capital Holdings Plc in group Polar Capital Holdings Plc More: the full row for Polar Capital Holdings Plc 2,132,138 $11.8M 0.05% +133,258 13F-HR Timeline Group ANDERA PARTNERS More: the full row for ANDERA PARTNERS 1,818,181 $10.1M 5.7% 0 13F-HR Timeline Yu Fan More: the full row for Yu Fan 1,500,000 $8.32M 8.58% 0 13F-HR Timeline BOOTHBAY FUND MANAGEMENT, LLC More: the full row for BOOTHBAY FUND MANAGEMENT, LLC 1,470,407 $8.16M 0.19% +811,436 13F-HR Timeline NEA Management Company, LLC More: the full row for NEA Management Company, LLC 1,462,586 $8.03M 0.46% 0 13F-HR Timeline Ikarian Capital, LLC in group Ikarian Capital, LLC More: the full row for Ikarian Capital, LLC 1,429,101 $7.84M 1.12% +926,500 13F-HR Timeline Group NEXTBio Capital Management LP More: the full row for NEXTBio Capital Management LP 1,333,484 $7.4M 3.44% +34,783 13F-HR Timeline RTW INVESTMENTS, LP More: the full row for RTW INVESTMENTS, LP 1,298,702 $7.21M 0.07% +1 13F-HR Timeline Deep Track Capital, LP More: the full row for Deep Track Capital, LP 1,222,453 $6.78M 0.14% +732,453 13F-HR Timeline Point72 Asset Management, L.P. in group Point72 Asset Management, L.P. More: the full row for Point72 Asset Management, L.P. 956,221 $5.31M 0.01% new 13F-HR Timeline Group AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 844,215 $4.69M <0.01% +228,742 13F-HR/A Timeline Group Ally Bridge Group (NY) LLC More: the full row for Ally Bridge Group (NY) LLC 745,300 $4.14M 4.11% -754,700 13F-HR Timeline Propel Bio Management, LLC More: the full row for Propel Bio Management, LLC 724,678 $3.99M 2.52% -275,322 13F-HR Timeline BVF INC/IL in group BVF INC/IL More: the full row for BVF INC/IL 686,040 $3.81M 0.12% 0 13F-HR Timeline Group MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 654,211 $3.63M <0.01% +482,118 13F-HR Timeline Group HighVista Strategies LLC More: the full row for HighVista Strategies LLC 615,666 $3.42M 0.94% new 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 613,357 $3.4M <0.01% +105,656 13F-HR Timeline Group Squadron Capital Management LLC More: the full row for Squadron Capital Management LLC 535,000 $2.97M 1.19% +235,000 13F-HR Timeline Integral Health Asset Management, LLC More: the full row for Integral Health Asset Management, LLC 400,000 $2.22M 0.12% new 13F-HR Timeline DIADEMA PARTNERS LP More: the full row for DIADEMA PARTNERS LP 352,399 $1.94M 0.8% +18,148 13F-HR Timeline Artisan Partners Limited Partnership More: the full row for Artisan Partners Limited Partnership 323,006 $1.79M <0.01% new 13F-HR Timeline Simplify Asset Management Inc. More: the full row for Simplify Asset Management Inc. 227,923 $1.26M 0.02% -109,739 13F-HR Timeline TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 226,406 $1.26M <0.01% +168,989 13F-HR Timeline Group Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 205,639 $1.14M <0.01% new 13F-HR Timeline Group Seven Fleet Capital Management LP More: the full row for Seven Fleet Capital Management LP 200,141 $1.11M 0.35% new 13F-HR/A Timeline GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 184,907 $1.03M <0.01% -244,688 13F-HR Timeline Group Hudson Bay Capital Management LP in group Hudson Bay Capital Management… More: the full row for Hudson Bay Capital Management LP 145,459 $807K <0.01% new 13F-HR Timeline Group Persistent Asset Partners Ltd More: the full row for Persistent Asset Partners Ltd 128,099 $711K 0.28% -1,612 13F-HR Timeline J. Goldman & Co LP More: the full row for J. Goldman & Co LP 103,518 $575K 0.03% -412,927 13F-HR Timeline Quadrature Capital Ltd in group Quadrature Capital Ltd More: the full row for Quadrature Capital Ltd 84,323 $468K 0.01% +17,394 13F-HR Timeline Group COMMONWEALTH EQUITY SERVICES, LLC More: the full row for COMMONWEALTH EQUITY SERVICES, LLC 77,561 $430K <0.01% 0 13F-HR Timeline JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 69,434 $385K <0.01% new 13F-HR Timeline Group XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 66,121 $367K 0.01% +48,068 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 64,950 $360K <0.01% +50,251 13F-HR Timeline Group PRELUDE CAPITAL MANAGEMENT, LLC More: the full row for PRELUDE CAPITAL MANAGEMENT, LLC 40,000 $222K 0.02% new 13F-HR Timeline ExodusPoint Capital Management, LP More: the full row for ExodusPoint Capital Management, LP 38,256 $212K <0.01% new 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 31,482 $175K <0.01% new 13F-HR Timeline Group Engineers Gate Manager LP More: the full row for Engineers Gate Manager LP 27,836 $154K <0.01% new 13F-HR Timeline WEALTH ENHANCEMENT ADVISORY SERVICES, L… More: the full row for WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 26,685 $146K <0.01% +915 13F-HR Timeline Quaker Wealth Management, LLC More: the full row for Quaker Wealth Management, LLC 24,960 $139K 0.04% new 13F-HR Timeline NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 24,467 $136K <0.01% new 13F-HR Timeline Cerity Partners LLC in group Cerity Partners LLC More: the full row for Cerity Partners LLC 20,000 $111K <0.01% 0 13F-HR Timeline Group NewEdge Advisors, LLC More: the full row for NewEdge Advisors, LLC 20,000 $111K <0.01% 0 13F-HR/A Timeline HRT FINANCIAL LP More: the full row for HRT FINANCIAL LP 18,854 $104K <0.01% new 13F-HR Timeline Virtu Financial LLC in group Virtu Financial LLC More: the full row for Virtu Financial LLC 18,729 $104K <0.01% +5,860 13F-HR Timeline Group China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 16,000 $88.8K 0.01% new 13F-HR Timeline BLAIR WILLIAM & CO/IL More: the full row for BLAIR WILLIAM & CO/IL 10,000 $55.5K <0.01% new 13F-HR Timeline Frec Markets, Inc. in group Frec Markets, Inc. More: the full row for Frec Markets, Inc. 10,000 $55.5K 0.01% new 13F-HR Timeline Group GAMMA Investing LLC More: the full row for GAMMA Investing LLC 4,515 $25.1K <0.01% +2,735 13F-HR Timeline RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 2,862 $15.9K <0.01% +230 13F-HR Timeline JONES FINANCIAL COMPANIES LLLP in group JONES FINANCIAL COMPANIES LLLP More: the full row for JONES FINANCIAL COMPANIES LLLP 881 $5.04K <0.01% new 13F-HR Timeline Group EverSource Wealth Advisors, LLC in group EverSource Wealth Advisors, L… More: the full row for EverSource Wealth Advisors, LLC 604 $3.35K <0.01% new 13F-HR/A Timeline Group Covestor Ltd More: the full row for Covestor Ltd 402 $2K <0.01% 0 13F-HR Timeline Atlantic Union Bankshares Corp in group Atlantic Union Bankshares Corp More: the full row for Atlantic Union Bankshares Corp 300 $1.67K <0.01% 0 13F-HR Timeline Group Bell Investment Advisors, Inc More: the full row for Bell Investment Advisors, Inc 76 $422 <0.01% new 13F-HR Timeline Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 2 $11 <0.01% new 13F-HR Timeline