PERCEPTIVE ADVISORS LLC in group PERCEPTIVE ADVISORS LLC More: the full row for PERCEPTIVE ADVISORS LLC 1,452,707 $115M 2.1% +125,000 13F-HR Timeline Group VIKING GLOBAL INVESTORS LP in group VIKING GLOBAL INVESTORS LP More: the full row for VIKING GLOBAL INVESTORS LP 1,437,705 $114M 0.3% -350,000 13F-HR Timeline Group MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 1,167,728 $92.3M 0.01% +724,872 13F-HR/A Timeline Group Sanofi More: the full row for Sanofi 1,157,926 $91.5M 29.47% 0 13F-HR Timeline HighTower Advisors, LLC More: the full row for HighTower Advisors, LLC 870,507 $68.8M 0.08% -1,252 13F-HR Timeline BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 777,383 $61.4M <0.01% +92,637 13F-HR Timeline Group VANGUARD GROUP INC in group VANGUARD GROUP INC More: the full row for VANGUARD GROUP INC 623,084 $49.2M <0.01% +28,166 13F-HR Timeline Group Sofinnova Investments, Inc. More: the full row for Sofinnova Investments, Inc. 454,657 $35.9M 1.55% +14,565 13F-HR Timeline Capital Research Global Investors in group Capital Research Global Inves… More: the full row for Capital Research Global Investors 421,575 $33.3M 0.01% new 13F-HR Timeline Group STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 374,961 $29.6M <0.01% +171,038 13F-HR Timeline Group Caligan Partners LP More: the full row for Caligan Partners LP 323,565 $25.6M 2.34% +87,182 13F-HR Timeline SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 297,116 $23.5M 0.03% new 13F-HR Timeline Group MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 275,917 $21.8M 0.02% -21,903 13F-HR Timeline Group PFM Health Sciences, LP More: the full row for PFM Health Sciences, LP 265,517 $21M 2.12% +25,873 13F-HR Timeline HEALTHCARE OF ONTARIO PENSION PLAN TRUS… More: the full row for HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 264,000 $20.9M 0.04% new 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 226,009 $17.9M <0.01% +4,089 13F-HR Timeline Group Schonfeld Strategic Advisors LLC More: the full row for Schonfeld Strategic Advisors LLC 214,725 $17M 0.09% +117,343 13F-HR Timeline Woodline Partners LP More: the full row for Woodline Partners LP 139,479 $11M 0.04% -197,111 13F-HR Timeline NORGES BANK More: the full row for NORGES BANK 133,300 $10.5M <0.01% new 13F-HR Timeline D. E. Shaw & Co., Inc. in group D. E. Shaw & Co., Inc. More: the full row for D. E. Shaw & Co., Inc. 122,101 $9.65M 0.01% +110,548 13F-HR Timeline Group Invesco Ltd. in group Invesco Ltd. More: the full row for Invesco Ltd. 112,396 $8.88M <0.01% +94,822 13F-HR Timeline Group CDC Financial, Inc. More: the full row for CDC Financial, Inc. 110,810 $8.75M 7.68% 13F-HR Timeline GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 100,617 $7.95M <0.01% +74,651 13F-HR/A Timeline Group BOOTHBAY FUND MANAGEMENT, LLC More: the full row for BOOTHBAY FUND MANAGEMENT, LLC 92,009 $7.27M 0.19% +13,197 13F-HR Timeline NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 88,509 $6.99M <0.01% -4,148 13F-HR Timeline Group SummitTX Capital, L.P. More: the full row for SummitTX Capital, L.P. 82,885 $6.55M 0.2% +28,742 13F-HR Timeline UBS Group AG group of 2 filers holding More: the full row for UBS Group AG 73,709 $5.82M +64,173 Timeline KENNEDY CAPITAL MANAGEMENT LLC More: the full row for KENNEDY CAPITAL MANAGEMENT LLC 71,488 $5.65M 0.12% -90,421 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 69,119 $5.46M <0.01% +51,287 13F-HR Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 55,759 $4.4M <0.01% +50,788 13F-HR Timeline Group RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 52,600 $4.16M 0.01% +44,200 13F-HR Timeline FMR LLC in group FMR LLC More: the full row for FMR LLC 46,269 $3.66M <0.01% +6,942 13F-HR Timeline Group Laird Norton Wetherby Trust Company, LLC in group Laird Norton Wetherby Trust C… More: the full row for Laird Norton Wetherby Trust Company, LLC 40,382 $3.19M 0.07% new 13F-HR Timeline Group ArrowMark Colorado Holdings LLC More: the full row for ArrowMark Colorado Holdings LLC 35,176 $2.78M 0.06% 0 13F-HR Timeline JANE STREET GROUP, LLC in group JANE STREET GROUP, LLC More: the full row for JANE STREET GROUP, LLC 33,019 $2.61M <0.01% -29,922 13F-HR Timeline Group MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 29,310 $2.32M <0.01% +2,068 13F-HR Timeline Group FRANKLIN RESOURCES INC in group Franklin Resources More: the full row for FRANKLIN RESOURCES INC 29,308 $2.32M <0.01% +12,144 13F-HR Timeline Group WELLINGTON MANAGEMENT GROUP LLP in group WELLINGTON MANAGEMENT GROUP L… More: the full row for WELLINGTON MANAGEMENT GROUP LLP 28,393 $2.24M <0.01% -1,366 13F-HR Timeline Group CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 27,341 $2.16M <0.01% -452 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 26,900 $2.13M <0.01% -30,294 13F-HR Timeline Group Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 26,748 $2.11M <0.01% -23,377 13F-HR Timeline Group ACADIAN ASSET MANAGEMENT LLC in group ACADIAN ASSET MANAGEMENT LLC More: the full row for ACADIAN ASSET MANAGEMENT LLC 25,390 $2M <0.01% -3,055 13F-HR Timeline Group Soleus Capital Management, L.P. More: the full row for Soleus Capital Management, L.P. 25,000 $1.98M 0.08% new 13F-HR Timeline Empirical Financial Services, LLC d.b.a… More: the full row for Empirical Financial Services, LLC d.b.a. Empirical Wealth Management 22,883 $1.81M 0.03% +299 13F-HR Timeline BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 21,879 $1.73M <0.01% +8,411 13F-HR Timeline Group Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 20,778 $1.64M <0.01% -17,356 13F-HR Timeline Group Corient Private Wealth LP in group Corient Private Wealth LP More: the full row for Corient Private Wealth LP 20,443 $1.61M <0.01% new 13F-HR/A Timeline Group Nuveen, LLC in group TIAA More: the full row for Nuveen, LLC 17,090 $1.35M <0.01% -494 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 17,059 $1.35M <0.01% +12,230 13F-HR Timeline Group ACUTA CAPITAL PARTNERS, LLC More: the full row for ACUTA CAPITAL PARTNERS, LLC 16,377 $1.29M 0.88% 0 13F-HR Timeline SG Americas Securities, LLC More: the full row for SG Americas Securities, LLC 16,088 $1.27M <0.01% new 13F-HR Timeline Groupe la Francaise in group Groupe la Francaise More: the full row for Groupe la Francaise 15,636 $1.24M 0.02% -31,698 13F-HR Timeline Group Voleon Capital Management LP More: the full row for Voleon Capital Management LP 15,008 $1.19M 0.03% new 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 14,850 $1.17M <0.01% +12,964 13F-HR Timeline Group Ethic Inc. More: the full row for Ethic Inc. 12,971 $1.02M 0.02% -1,516 13F-HR Timeline Mariner, LLC in group Mariner, LLC More: the full row for Mariner, LLC 12,746 $1.01M <0.01% -4,596 13F-HR Timeline Group Jain Global LLC More: the full row for Jain Global LLC 12,098 $956K 0.01% new 13F-HR Timeline VICTORY CAPITAL MANAGEMENT INC More: the full row for VICTORY CAPITAL MANAGEMENT INC 11,963 $945K <0.01% new 13F-HR Timeline RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 11,435 $903K <0.01% -2,300 13F-HR Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 10,813 $854K <0.01% +3,214 13F-HR Timeline Group Meridian Wealth Advisors, LLC More: the full row for Meridian Wealth Advisors, LLC 10,500 $830K 0.11% -14,500 13F-HR Timeline JACOBS LEVY EQUITY MANAGEMENT, INC More: the full row for JACOBS LEVY EQUITY MANAGEMENT, INC 10,141 $801K <0.01% -3,578 13F-HR Timeline Quantinno Capital Management LP More: the full row for Quantinno Capital Management LP 10,038 $793K <0.01% -1,789 13F-HR Timeline XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 9,021 $713K 0.02% new 13F-HR Timeline Group BRIDGEWAY CAPITAL MANAGEMENT, LLC More: the full row for BRIDGEWAY CAPITAL MANAGEMENT, LLC 9,000 $711K 0.01% -7,500 13F-HR Timeline ALLIANCEBERNSTEIN L.P. More: the full row for ALLIANCEBERNSTEIN L.P. 8,950 $707K <0.01% -10,280 13F-HR Timeline Jefferies Financial Group Inc. in group Jefferies Financial Group Inc. More: the full row for Jefferies Financial Group Inc. 8,901 $703K 0.01% new 13F-HR Timeline Group CREDIT INDUSTRIEL ET COMMERCIAL More: the full row for CREDIT INDUSTRIEL ET COMMERCIAL 8,656 $684K 0.1% -20,302 13F-HR Timeline Rafferty Asset Management, LLC More: the full row for Rafferty Asset Management, LLC 8,582 $678K <0.01% new 13F-HR Timeline AQR CAPITAL MANAGEMENT LLC in group AQR CAPITAL MANAGEMENT LLC More: the full row for AQR CAPITAL MANAGEMENT LLC 7,501 $593K <0.01% +1,503 13F-HR Timeline Group Belvedere Trading LLC More: the full row for Belvedere Trading LLC 7,402 $585K 0.11% +1,125 13F-HR Timeline DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 6,638 $524K <0.01% new 13F-HR Timeline Group PSP Research LLC More: the full row for PSP Research LLC 6,389 $505K 0.44% 13F-HR Timeline Creative Planning in group Creative Planning More: the full row for Creative Planning 5,708 $451K <0.01% new 13F-HR Timeline Group VOYA INVESTMENT MANAGEMENT LLC in group VOYA INVESTMENT MANAGEMENT LLC More: the full row for VOYA INVESTMENT MANAGEMENT LLC 5,564 $440K <0.01% new 13F-HR Timeline Group Janney Montgomery Scott LLC More: the full row for Janney Montgomery Scott LLC 5,495 $434K <0.01% new 13F-HR Timeline Mirae Asset Global Investments Co., Ltd. group of 2 filers holding More: the full row for Mirae Asset Global Investments Co., Ltd. 5,419 $428K +729 Timeline GROUP ONE TRADING LLC More: the full row for GROUP ONE TRADING LLC 5,358 $423K 0.01% new 13F-HR Timeline PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 5,334 $422K <0.01% new 13F-HR Timeline MetLife Investment Management, LLC in group MetLife Investment Management… More: the full row for MetLife Investment Management, LLC 5,320 $420K <0.01% -2,105 13F-HR Timeline Group Harvest Investment Services, LLC More: the full row for Harvest Investment Services, LLC 5,049 $399K 0.08% new 13F-HR Timeline TUDOR INVESTMENT CORP ET AL More: the full row for TUDOR INVESTMENT CORP ET AL 4,642 $367K <0.01% new 13F-HR Timeline STATE BOARD OF ADMINISTRATION OF FLORID… More: the full row for STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 3,800 $300K <0.01% new 13F-HR Timeline Birchview Capital, LP More: the full row for Birchview Capital, LP 3,698 $292K 0.17% -28,000 13F-HR Timeline Jump Financial, LLC in group Jump Financial, LLC More: the full row for Jump Financial, LLC 3,504 $277K <0.01% new 13F-HR Timeline Group NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 3,472 $274K <0.01% 0 13F-HR Timeline Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 3,398 $268K <0.01% new 13F-HR Timeline Group Presidio Capital Management, LLC More: the full row for Presidio Capital Management, LLC 3,394 $268K 0.08% new 13F-HR Timeline Virtus Investment Advisers, LLC in group Virtus Investment Advisers, L… More: the full row for Virtus Investment Advisers, LLC 3,343 $264K 0.07% new 13F-HR Timeline Group PROFUND ADVISORS LLC More: the full row for PROFUND ADVISORS LLC 3,271 $258K 0.01% new 13F-HR Timeline INTECH INVESTMENT MANAGEMENT LLC More: the full row for INTECH INVESTMENT MANAGEMENT LLC 3,242 $256K <0.01% new 13F-HR Timeline AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 3,051 $241K <0.01% new 13F-HR Timeline Group LANARK FINANCIAL, INC. More: the full row for LANARK FINANCIAL, INC. 3,000 $237K 0.02% 0 13F-HR Timeline Mitsubishi UFJ Asset Management Co., Lt… in group Mitsubishi UFJ Trust & Bankin… More: the full row for Mitsubishi UFJ Asset Management Co., Ltd. 3,101 $233K <0.01% new 13F-HR Timeline Group MANUFACTURERS LIFE INSURANCE COMPANY, T… in group MANUFACTURERS LIFE INSURANCE … More: the full row for MANUFACTURERS LIFE INSURANCE COMPANY, THE 2,785 $220K <0.01% new 13F-HR Timeline Group Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 2,660 $210K <0.01% 0 13F-HR Timeline China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 2,370 $187K 0.01% -169 13F-HR Timeline AlphaQuest LLC More: the full row for AlphaQuest LLC 2,192 $173K 0.01% new 13F-HR Timeline Hurley Capital, LLC More: the full row for Hurley Capital, LLC 1,660 $131K 0.07% new 13F-HR Timeline DIADEMA PARTNERS LP More: the full row for DIADEMA PARTNERS LP 1,299 $103K 0.06% new 13F-HR Timeline PUBLIC EMPLOYEES RETIREMENT SYSTEM OF O… More: the full row for PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 1,200 $94.8K <0.01% 0 13F-HR Timeline SIMPLEX TRADING, LLC More: the full row for SIMPLEX TRADING, LLC 1,145 $90.5K <0.01% new 13F-HR Timeline Optiver Holding B.V. in group Optiver Holding B.V. More: the full row for Optiver Holding B.V. 932 $73.6K <0.01% +818 13F-HR Timeline Group NATIXIS in group Natixis Investment Managers More: the full row for NATIXIS 889 $70.2K <0.01% -1,111 13F-HR Timeline Group Daiwa Securities Group Inc. in group Daiwa Securities Group Inc. More: the full row for Daiwa Securities Group Inc. 841 $66K <0.01% new 13F-HR Timeline Group Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 794 $62.7K <0.01% +26 13F-HR Timeline Group Ameritas Investment Partners, Inc. in group Ameritas Investment Partners,… More: the full row for Ameritas Investment Partners, Inc. 736 $58.1K <0.01% -117 13F-HR Timeline Group Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 659 $52.1K <0.01% -384 13F-HR Timeline Group CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 558 $44.1K <0.01% -10 13F-HR Timeline Sterling Capital Management LLC More: the full row for Sterling Capital Management LLC 528 $41.7K <0.01% -97 13F-HR Timeline Zurcher Kantonalbank (Zurich Cantonalba… More: the full row for Zurcher Kantonalbank (Zurich Cantonalbank) 498 $39.3K <0.01% 0 13F-HR Timeline ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 357 $29K <0.01% -109 13F-HR Timeline Group Persistent Asset Partners Ltd More: the full row for Persistent Asset Partners Ltd 346 $27.3K 0.01% new 13F-HR Timeline AMALGAMATED BANK More: the full row for AMALGAMATED BANK 285 $23K <0.01% -77 13F-HR Timeline GF FUND MANAGEMENT CO. LTD. More: the full row for GF FUND MANAGEMENT CO. LTD. 285 $22.5K <0.01% -22 13F-HR Timeline FNY Investment Advisers, LLC More: the full row for FNY Investment Advisers, LLC 250 $19K 0.01% 0 13F-HR Timeline US BANCORP \DE\ in group US BANCORP \DE\ More: the full row for US BANCORP \DE\ 203 $16K <0.01% -14 13F-HR Timeline Group Versant Capital Management, Inc More: the full row for Versant Capital Management, Inc 168 $13.3K <0.01% 0 13F-HR Timeline GAMMA Investing LLC More: the full row for GAMMA Investing LLC 165 $13K <0.01% +26 13F-HR Timeline EverSource Wealth Advisors, LLC in group EverSource Wealth Advisors, L… More: the full row for EverSource Wealth Advisors, LLC 162 $12.8K <0.01% +122 13F-HR Timeline Group CWM, LLC in group CWM, LLC More: the full row for CWM, LLC 155 $12K <0.01% +7 13F-HR Timeline Group Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 121 $9.56K <0.01% new 13F-HR/A Timeline Torren Management, LLC More: the full row for Torren Management, LLC 110 $8.69K <0.01% 13F-HR Timeline NISA INVESTMENT ADVISORS, LLC More: the full row for NISA INVESTMENT ADVISORS, LLC 104 $8.22K <0.01% +93 13F-HR Timeline OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 68 $5.37K <0.01% -51 13F-HR Timeline Group PNC Financial Services Group, Inc. in group PNC Financial Services Group,… More: the full row for PNC Financial Services Group, Inc. 41 $3.24K <0.01% 0 13F-HR Timeline Group Farther Finance Advisors, LLC More: the full row for Farther Finance Advisors, LLC 38 $3K <0.01% 0 13F-HR Timeline LOS ANGELES CAPITAL MANAGEMENT LLC More: the full row for LOS ANGELES CAPITAL MANAGEMENT LLC 38 $2.98K <0.01% new 13F-HR Timeline SageView Advisory Group, LLC More: the full row for SageView Advisory Group, LLC 28 $2.21K <0.01% new 13F-HR Timeline ROTHSCHILD INVESTMENT LLC More: the full row for ROTHSCHILD INVESTMENT LLC 22 $1.74K <0.01% +2 13F-HR Timeline Aster Capital Management (DIFC) Ltd More: the full row for Aster Capital Management (DIFC) Ltd 17 $1.34K <0.01% new 13F-HR Timeline Rockefeller Capital Management L.P. in group Rockefeller Capital Managemen… More: the full row for Rockefeller Capital Management L.P. 13 $1.03K <0.01% 0 13F-HR/A Timeline Group Sunbelt Securities, Inc. More: the full row for Sunbelt Securities, Inc. 8 $632 <0.01% 0 13F-HR Timeline True Wealth Design, LLC More: the full row for True Wealth Design, LLC 4 $316 <0.01% 0 13F-HR Timeline SIGNATUREFD, LLC More: the full row for SIGNATUREFD, LLC 2 $158 <0.01% 0 13F-HR Timeline Essential Partners LLC More: the full row for Essential Partners LLC 2 $158 <0.01% 0 13F-HR Timeline