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Disclosery

DNLI DENALI THERAPEUTICS INC

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Stock (common), issuer CIK 1714899

237 managers (241 13F filers) reported a position in DNLI shares at 2025-09-30, 135,496,792 shares in all. 33 filers opened a position and 23 filers sold out during the quarter.

Managers
237
13F filers
241
New
33
Added
91
Reduced
67
Sold out
23
Shares held by filers
135,496,792

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
BlackRock, Inc.in group BlackRock, Inc.12,289,626$178M<0.01%+236,28113F-HRTimelineGroup
VANGUARD GROUP INCgroup of 2 filers holding12,005,444$174M+179,380Timeline
BAILLIE GIFFORD & COin group BAILLIE GIFFORD & CO11,591,585$168M0.12%-363,73813F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding7,477,390$109M+264,349Timeline
FMR LLCin group FMR LLC6,340,316$92.1M<0.01%-1,198,15213F-HRTimelineGroup
T. Rowe Price Investment Management, In…5,638,567$81.9M0.05%+2,391,63313F-HRTimeline
STATE STREET CORPin group STATE STREET CORP5,464,261$79.3M<0.01%+946,26713F-HRTimelineGroup
Temasek Holdings (Private) Ltdin group Temasek Holdings (Private) Ltd5,355,832$77.8M0.27%013F-HRTimelineGroup
Capital Research Global Investorsin group Capital Research Global Inves…4,760,858$69.1M0.01%+10,27913F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/4,568,368$66.3M0.01%-2,013,92713F-HRTimeline
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP3,731,695$54.2M0.39%013F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.3,520,414$51.1M0.02%+383,27413F-HRTimeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC3,466,057$50.3M<0.01%+293,75213F-HRTimelineGroup
Crestline Management, L.P.3,410,732$49.5M85.26%-450,00013F-HRTimeline
Holocene Advisors, LP3,135,712$45.5M0.1%+2,732,54013F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.2,519,535$36.6M0.08%+305,58813F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP2,357,214$34.2M0.01%-55,71413F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC2,163,705$31.4M<0.01%+298,38113F-HRTimelineGroup
STEMPOINT CAPITAL LP1,734,659$25.2M5.08%+1,026,74413F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY1,689,492$24.5M<0.01%+377,47613F-HR/ATimelineGroup
Fisher Asset Management, LLC1,631,496$23.7M0.01%+115,50513F-HRTimeline
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC1,307,171$19M0.01%+406,67013F-HRTimelineGroup
PRINCIPAL FINANCIAL GROUP INCin group PRINCIPAL FINANCIAL GROUP INC1,271,190$18.5M0.01%+198,20713F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP1,234,179$17.9M<0.01%+32,47013F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co1,151,384$16.7M<0.01%+95,36513F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc1,113,586$16.2M0.03%+210,83513F-HRTimelineGroup
Foresite Capital Management VI LLCin group Foresite Capital Management V…1,000,000$14.5M5.61%new13F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/961,138$14M<0.01%+310,91613F-HR/ATimelineGroup
VOLORIDGE INVESTMENT MANAGEMENT, LLC936,230$13.6M0.05%+165,70313F-HRTimeline
Casdin Capital, LLC890,000$12.9M1.08%013F-HRTimeline
Candriam S.C.A.833,582$12.1M0.06%-10,66713F-HRTimeline
Siren, L.L.C.in group Siren, L.L.C.821,513$11.9M0.47%013F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp800,747$11.6M<0.01%+9,99113F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP787,029$11.4M0.01%-618,22113F-HRTimelineGroup
MASTERS CAPITAL MANAGEMENT LLC750,000$10.9M1.75%+150,00013F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC688,224$9.99M0.01%-560,72913F-HRTimelineGroup
Cercano Management LLC625,000$9.07M0.35%013F-HRTimeline
Ensign Peak Advisors, Inc534,071$7.75M0.01%+60,37613F-HR/ATimeline
SEGALL BRYANT & HAMILL, LLC512,958$7.45M0.1%+12,39913F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…499,162$7.25M0.01%+84,05013F-HRTimelineGroup
Yiheng Capital Management, L.P.469,981$6.82M2.26%013F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC437,001$6.35M<0.01%+11,02013F-HR/ATimelineGroup
Trexquant Investment LP430,566$6.25M0.06%+321,32413F-HRTimeline
Palo Alto Investors LP408,006$5.92M1.1%+168,19713F-HRTimeline
TD Asset Management Inc394,600$5.73M<0.01%-101,69013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA372,176$5.4M<0.01%-17,97913F-HRTimelineGroup
Clarius Group, LLC359,745$5.22M0.31%-9,25013F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC357,341$5.19M<0.01%+39,14813F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding356,292$5.17M+309,392Timeline
Hudson Bay Capital Management LPin group Hudson Bay Capital Management…305,000$4.43M0.03%+15,00013F-HR/ATimelineGroup
Pier Capital, LLC301,171$4.37M0.68%-13,62513F-HRTimeline
AXA Investment Managers S.A.294,732$4.28M0.01%13F-HRTimeline
Marex Group Ltdin group Marex Group Ltd291,000$4.23M0.05%+29,00013F-HRTimelineGroup
Nuveen, LLCin group TIAA284,777$4.13M<0.01%-310,44013F-HRTimelineGroup
Swiss National Bank267,500$3.88M<0.01%+16,60013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS264,061$3.83M<0.01%+244,97913F-HRTimelineGroup
Lynx1 Capital Management LPin group Lynx1 Capital Management LP261,687$3.8M0.77%new13F-HRTimelineGroup
Boxer Capital Management, LLCin group Boxer Capital Management, LLC250,000$3.63M1.16%new13F-HR/ATimelineGroup
Invesco Ltd.in group Invesco Ltd.249,467$3.62M<0.01%+29,67213F-HRTimelineGroup
Cubist Systematic Strategies, LLC230,968$3.35M0.05%-165,61813F-HRTimeline
Qube Research & Technologies Ltd227,990$3.31M<0.01%new13F-HRTimeline
Schonfeld Strategic Advisors LLC226,203$3.28M0.02%new13F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC224,903$3.27M<0.01%+139,57113F-HRTimelineGroup
Campbell & CO Investment Adviser LLC216,774$3.15M0.24%+74,06613F-HRTimeline
SCHRODER INVESTMENT MANAGEMENT GROUP209,595$3.04M<0.01%-176,94413F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\207,594$3.01M<0.01%+71,62513F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …205,845$2.99M<0.01%-109,25713F-HRTimelineGroup
EDMOND DE ROTHSCHILD HOLDING S.A.in group EDMOND DE ROTHSCHILD HOLDING …205,680$2.99M0.05%013F-HRTimelineGroup
RHUMBLINE ADVISERS201,565$2.93M<0.01%-10,93813F-HRTimeline
SCS Capital Management LLC197,998$2.87M0.03%013F-HRTimeline
Rafferty Asset Management, LLC182,886$2.66M0.01%+60,62413F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO175,021$2.54M<0.01%-16,59213F-HR/ATimelineGroup
TEACHERS RETIREMENT SYSTEM OF THE STATE…171,553$2.49M0.02%013F-HRTimeline
DAFNA Capital Management LLC168,500$2.45M0.6%013F-HRTimeline
Jump Financial, LLCin group Jump Financial, LLC166,399$2.42M0.03%new13F-HR/ATimelineGroup
Legal & General Group Plcin group Legal & General Group Plc143,952$2.09M<0.01%+12,19713F-HRTimelineGroup
State of New Jersey Common Pension Fund…in group State of New Jersey Common Pe…139,663$2.03M0.01%+1,78313F-HRTimelineGroup
GROUPAMA ASSET MANAGMENT135,758$1.97M0.03%-39,77313F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding135,540$1.97M-4,775Timeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…129,526$1.88M<0.01%+10,19913F-HRTimeline
Edgestream Partners, L.P.123,819$1.8M0.05%-219,10413F-HRTimeline
Woodline Partners LP113,517$1.65M0.01%013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN104,179$1.51M<0.01%+14,54013F-HRTimelineGroup
ALGERT GLOBAL LLC101,260$1.47M0.02%+15,42013F-HR/ATimeline
Rhenman & Partners Asset Management AB100,000$1.45M0.16%013F-HRTimeline
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC99,561$1.45M<0.01%-2,47213F-HRTimelineGroup
Integrated Wealth Concepts LLC91,074$1.32M0.01%-4,97213F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC80,518$1.17M<0.01%new13F-HRTimelineGroup
STATE OF WISCONSIN INVESTMENT BOARD80,126$1.16M<0.01%+49913F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…79,075$1.15M0.01%013F-HRTimelineGroup
Savvy Advisors, Inc.77,093$1.12M0.05%-20,70013F-HRTimeline
AlphaQuest LLC74,422$1.08M0.07%+51,45813F-HRTimeline
ALPS ADVISORS INCin group ALPS ADVISORS INC70,230$1.02M0.01%-8,12613F-HRTimelineGroup
Engineers Gate Manager LP69,216$1.01M0.01%-46,88513F-HRTimeline
PIER 88 INVESTMENT PARTNERS LLC67,440$979K0.18%+10,29013F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd65,345$949K0.05%new13F-HRTimelineGroup
TT International Asset Management LTD65,000$944K0.18%013F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources64,634$938K<0.01%+10913F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson60,028$872K<0.01%013F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC59,800$868K<0.01%-135,90013F-HRTimeline
DekaBank Deutsche Girozentrale59,800$864K<0.01%013F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…59,234$860K<0.01%-5,605,49913F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL56,368$818K0.01%+92013F-HR/ATimeline
Aquatic Capital Management LLC56,237$817K0.02%new13F-HRTimeline
Creative Planningin group Creative Planning54,834$796K<0.01%-2,84413F-HRTimelineGroup
IRONWOOD INVESTMENT MANAGEMENT LLC52,786$766K0.33%-42613F-HRTimeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC51,516$748K0.07%+15,80013F-HRTimelineGroup
Dana Investment Advisors, Inc.50,716$736K0.02%+15,15513F-HRTimeline
Knights of Columbus Asset Advisors LLC50,190$729K0.04%+11,71113F-HRTimeline
GUGGENHEIM CAPITAL LLCin group GUGGENHEIM CAPITAL LLC49,525$719K0.01%-2,33513F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…47,459$689K<0.01%+3,87213F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC46,797$679K0.01%-25,06913F-HRTimeline
MAI Capital Management46,526$676K<0.01%013F-HRTimeline
JACOBS LEVY EQUITY MANAGEMENT, INC45,969$667K<0.01%new13F-HRTimeline
Pathstone Holdings, LLCin group Pathstone Holdings, LLC45,830$665K<0.01%+79013F-HRTimelineGroup
JENNISON ASSOCIATES LLC45,445$660K<0.01%new13F-HRTimeline
CANTOR FITZGERALD, L. P.in group CANTOR FITZGERALD, L. P.45,000$653K0.01%new13F-HR/ATimelineGroup
Employees Retirement System of Texas43,769$636K0.01%013F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…40,986$595K<0.01%-120,15013F-HRTimelineGroup
ARIZONA STATE RETIREMENT SYSTEM40,813$593K<0.01%+2,69913F-HRTimeline
PROFUND ADVISORS LLC40,156$583K0.02%+13,43313F-HRTimeline
Graham Capital Management, L.P.39,319$571K0.02%-25,48013F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND38,478$559K<0.01%013F-HRTimeline
Handelsbanken Fonder AB38,300$556K<0.01%013F-HRTimeline
SG Americas Securities, LLC38,201$555K<0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…36,663$532K<0.01%+6,26913F-HRTimeline
Thrivent Financial for Lutheransin group Thrivent Financial for Luther…35,619$517K<0.01%-32,29813F-HRTimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…34,168$496K<0.01%013F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS33,827$491K<0.01%-1,39413F-HRTimeline
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC32,415$471K<0.01%-1,12313F-HRTimelineGroup
KLP KAPITALFORVALTNING AS29,900$434K<0.01%+3,80013F-HRTimeline
ProShare Advisors LLC27,855$404K<0.01%-4,72713F-HRTimeline
Cinctive Capital Management LP27,792$404K0.02%+3,48213F-HRTimeline
Erste Asset Management GmbHin group Erste Asset Management GmbH26,900$391K<0.01%013F-HRTimelineGroup
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …26,223$381K<0.01%+4,73913F-HRTimelineGroup
China Universal Asset Management Co., L…25,629$372K0.03%-3,54913F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC25,326$368K<0.01%-1,27013F-HRTimelineGroup
Quantinno Capital Management LP24,707$359K<0.01%new13F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC24,139$350K<0.01%+2,92213F-HRTimelineGroup
EntryPoint Capital, LLC24,058$349K0.14%new13F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC23,805$346K<0.01%-12,10313F-HRTimelineGroup
OXFORD ASSET MANAGEMENT LLP22,231$323K0.11%new13F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
HighTower Advisors, LLC21,322$310K<0.01%-1,21113F-HRTimeline
Verition Fund Management LLC17,629$256K<0.01%-33,18013F-HRTimeline
Jain Global LLC17,414$253K<0.01%+2,92813F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC16,938$246K<0.01%+6013F-HRTimelineGroup
Breakwater Capital Group15,866$230K0.03%-1,23013F-HRTimeline
VICTORY CAPITAL MANAGEMENT INC15,064$219K<0.01%-30,55213F-HRTimeline
CITIGROUP INCin group CITIGROUP INC14,936$217K<0.01%-61,37913F-HRTimelineGroup
CIBC Bancorp USA Inc.group of 2 filers holding14,118$205K+14,083Timeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC14,004$201K<0.01%+3,95613F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…13,799$200K<0.01%+11,24113F-HRTimelineGroup
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co13,434$195K<0.01%013F-HRTimelineGroup
MONECO ADVISORS, LLC12,478$181K0.02%+2,00013F-HRTimeline
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…12,238$178K<0.01%013F-HRTimeline
Aigen Investment Management, LP12,075$175K0.03%+1,41313F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…11,065$161K<0.01%-2,45713F-HRTimelineGroup
Empowered Funds, LLC11,037$160K<0.01%-3,78313F-HRTimeline
LPL Financial LLC10,648$155K<0.01%new13F-HRTimeline
INTRUST BANK NA10,575$154K0.01%new13F-HRTimeline
XPONANCE LLC10,400$151K<0.01%+4813F-HRTimeline
Sterling Capital Management LLC8,654$126K<0.01%+5,26813F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…8,290$120K<0.01%+5413F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…7,624$111K0.03%+1,32413F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…7,376$107K<0.01%-6,29313F-HRTimelineGroup
Caption Management, LLC7,366$107K0.01%new13F-HRTimeline
KBC Group NVin group KBC Group NV4,495$65K<0.01%013F-HRTimelineGroup
Quarry LP4,375$63.5K0.02%new13F-HRTimeline
AMALGAMATED BANK4,305$63K<0.01%013F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC3,937$57.2K<0.01%+31713F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.3,146$45.7K<0.01%-53913F-HRTimeline
CWM, LLCin group CWM, LLC2,397$35K<0.01%+12213F-HRTimelineGroup
State of Wyoming2,154$31.3K<0.01%+5513F-HRTimeline
Johnson Financial Group, Inc.in group Johnson Financial Group, Inc.1,975$28.7K<0.01%new13F-HRTimelineGroup
Caitong International Asset Management …1,528$22.2K0.02%+1,32813F-HRTimeline
SHELL ASSET MANAGEMENT CO1,492$22K<0.01%-2,51713F-HRTimeline
BARTLETT & CO. WEALTH MANAGEMENT LLC1,500$21.8K<0.01%013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC1,483$21.5K<0.01%+26613F-HRTimeline
Versant Capital Management, Inc1,476$21.4K<0.01%+19013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.1,388$20.9K<0.01%-20713F-HRTimelineGroup
COMERICA BANK1,284$18.6K<0.01%013F-HRTimeline
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …1,271$18K<0.01%+13213F-HRTimelineGroup
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…1,083$15.7K<0.01%new13F-HRTimelineGroup
Mitsubishi UFJ Asset Management Co., Lt…in group Mitsubishi UFJ Trust & Bankin…1,001$14.5K<0.01%013F-HRTimelineGroup
Smartleaf Asset Management LLC954$13.9K<0.01%+50013F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.896$13K<0.01%+313F-HRTimelineGroup
QUADRANT CAPITAL GROUP LLC782$11.4K<0.01%new13F-HRTimeline
GAMMA Investing LLC729$10.6K<0.01%-2013F-HRTimeline
Nemes Rush Group LLC700$10.2K<0.01%013F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\696$10.1K<0.01%+25513F-HRTimelineGroup
Covestor Ltd579$8K<0.01%-113F-HRTimeline
LANARK FINANCIAL, INC.532$7.72K<0.01%013F-HRTimeline
Groupe la Francaisein group Groupe la Francaise620$7.67K<0.01%new13F-HRTimelineGroup
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.475$7K<0.01%013F-HRTimelineGroup
Parallel Advisors, LLC434$6.3K<0.01%-11113F-HRTimeline
NewEdge Advisors, LLC400$5.81K<0.01%013F-HRTimeline
HUNTINGTON NATIONAL BANKin group HUNTINGTON NATIONAL BANK308$4.47K<0.01%+3813F-HRTimelineGroup
Private Wealth Management Group, LLC296$4.3K<0.01%013F-HRTimeline
City State Bank250$3.63K<0.01%013F-HRTimeline
SIGNATUREFD, LLC230$3.34K<0.01%-9913F-HRTimeline