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Disclosery

ARDX ARDELYX INC

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COM (common), issuer CIK 1437402

226 managers (229 13F filers) reported a position in ARDX shares at 2025-12-31, 166,857,855 shares in all. 32 filers opened a position and 26 filers sold out during the quarter.

Managers
226
13F filers
229
New
32
Added
79
Reduced
84
Sold out
26
Shares held by filers
166,857,855

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
BlackRock, Inc.in group BlackRock, Inc.21,139,105$123M<0.01%+315,52513F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC18,979,483$111M<0.01%+610,16213F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson14,514,692$84.6M0.04%+690,59913F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP11,912,339$69.4M<0.01%+2,193,64913F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC11,909,511$69.4M0.05%+4,267,52413F-HRTimelineGroup
NOMURA ASSET MANAGEMENT CO LTDgroup of 2 filers holding9,328,744$54.4M+9,162,752Timeline
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC5,827,618$34M<0.01%+70,83213F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP5,188,639$30.2M0.03%-3,754,40313F-HRTimelineGroup
Nuveen, LLCin group TIAA5,164,549$30.1M0.01%-10,40413F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding4,222,669$24.6M+117,221Timeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC3,064,746$17.9M<0.01%+479,86913F-HR/ATimelineGroup
MORGAN STANLEYin group MORGAN STANLEY2,358,806$13.8M<0.01%-526,53413F-HR/ATimelineGroup
Rock Springs Capital Management LP2,299,473$13.4M0.69%+13,20013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/2,208,693$12.9M<0.01%-445,50413F-HRTimelineGroup
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co2,117,293$12.3M<0.01%-77,46113F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC2,060,667$12M0.01%-133,05813F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC2,025,083$11.8M0.01%-119,04113F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP2,019,285$11.8M<0.01%-98,70713F-HRTimelineGroup
ORACLE INVESTMENT MANAGEMENT INC1,872,624$10.9M7.15%+368,79813F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP1,854,755$10.8M0.01%-19,14813F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC1,794,793$10.5M0.02%+104,70013F-HRTimeline
Eversept Partners, LP1,715,129$10M0.56%+285,75213F-HRTimeline
J. Goldman & Co LP1,622,736$9.46M0.37%+1,532,23613F-HRTimeline
ARROWSTREET CAPITAL, LIMITED PARTNERSHIPin group ARROWSTREET CAPITAL, LIMITED …1,424,878$8.31M<0.01%+845,85513F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.1,411,267$8.23M0.01%-1,901,78313F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC1,327,453$7.74M0.01%-201,07913F-HRTimelineGroup
AIGH Capital Management LLC1,150,000$6.7M1.98%+951,50013F-HRTimeline
Qube Research & Technologies Ltd1,096,117$6.39M0.01%new13F-HRTimeline
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP1,036,492$6.04M<0.01%+853,89213F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding1,009,591$5.89M+178,162Timeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS1,000,926$5.84M<0.01%+135,66813F-HRTimelineGroup
Hennion & Walsh Asset Management, Inc.959,540$5.59M0.19%+179,19213F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.958,690$5.59M0.01%new13F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…776,205$4.53M0.01%+156,20013F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC763,364$4.45M<0.01%+34,72213F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO736,190$4.29M<0.01%-267,09913F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp723,158$4.22M<0.01%-16,23013F-HRTimelineGroup
Freestone Grove Partners LP699,133$4.08M0.03%+297,37813F-HRTimeline
FMR LLCin group FMR LLC677,436$3.95M<0.01%+656,04513F-HRTimelineGroup
PANAGORA ASSET MANAGEMENT INC659,160$3.84M0.01%-52713F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\500,195$2.92M<0.01%+306,19913F-HRTimelineGroup
Y-Intercept (Hong Kong) Ltd499,668$2.91M0.07%+193,12113F-HRTimeline
Swiss National Bank475,200$2.77M<0.01%+11,30013F-HRTimeline
Rafferty Asset Management, LLC390,214$2.27M0.01%+75,43313F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC388,840$2.27M<0.01%-60,37513F-HRTimelineGroup
SCHRODER INVESTMENT MANAGEMENT GROUP368,448$2.14M<0.01%new13F-HRTimeline
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …347,609$2.03M<0.01%+2,53213F-HRTimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC346,142$2.02M<0.01%-50,67813F-HRTimelineGroup
Trexquant Investment LP327,159$1.91M0.02%-177,16913F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN318,413$1.86M<0.01%+117,17613F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.317,410$1.85M<0.01%+59,59713F-HRTimelineGroup
Clay Northam Wealth Management, LLC315,015$1.84M1.02%-8,45013F-HRTimeline
Pekin Hardy Strauss, Inc.305,230$1.78M0.16%-97,00013F-HRTimeline
RHUMBLINE ADVISERS297,924$1.74M<0.01%-42,96413F-HRTimeline
CAPITAL FUND MANAGEMENT S.A.283,892$1.66M0.02%-211,46113F-HRTimeline
Raiffeisen Bank International AGin group Raiffeisen Bank International…270,000$1.57M0.02%new13F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc268,263$1.56M<0.01%-87813F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.267,340$1.56M<0.01%013F-HRTimeline
DIADEMA PARTNERS LP252,198$1.47M0.88%-147,80213F-HRTimeline
IEQ CAPITAL, LLC246,434$1.44M<0.01%-7,96713F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/234,466$1.37M<0.01%+7,14613F-HRTimeline
Walleye Capital LLCin group Walleye Capital LLC221,308$1.29M0.01%-989,76313F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…217,662$1.27M<0.01%+1913F-HRTimeline
Jump Financial, LLCin group Jump Financial, LLC199,470$1.16M0.01%+161,87013F-HRTimelineGroup
Headlands Technologies LLC199,280$1.16M0.1%+108,11313F-HRTimeline
MACKENZIE FINANCIAL CORP199,550$1.16M<0.01%+22,71513F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD195,944$1.14M<0.01%-49,19413F-HRTimeline
MONIMUS CAPITAL MANAGEMENT, LP194,734$1.14M0.75%-7,57713F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC193,769$1.13M<0.01%+103,78713F-HRTimelineGroup
SG Americas Securities, LLC171,580$1M<0.01%+39,65513F-HRTimeline
Thrivent Financial for Lutheransin group Thrivent Financial for Luther…162,786$949K<0.01%+6,35813F-HRTimelineGroup
LPL Financial LLC159,932$932K<0.01%-2,13213F-HRTimeline
FRANKLIN RESOURCES INCin group Franklin Resources154,698$902K<0.01%-601,43313F-HRTimelineGroup
HARBOR CAPITAL ADVISORS, INC.153,825$897K0.07%+53,71713F-HRTimeline
GROUP ONE TRADING LLC153,811$897K0.03%+60,54013F-HRTimeline
SIMPLEX TRADING, LLC151,934$886K0.02%-57,29913F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding145,836$850K+10,793Timeline
PROFUND ADVISORS LLC145,333$847K0.03%+76,07113F-HRTimeline
DekaBank Deutsche Girozentrale100,000$806K<0.01%013F-HRTimeline
PFG Investments, LLC137,860$804K0.04%-43513F-HRTimeline
Engineers Gate Manager LP137,582$802K0.01%-102,80813F-HRTimeline
ALGERT GLOBAL LLC134,206$782K0.01%+48,47013F-HR/ATimeline
CANADA PENSION PLAN INVESTMENT BOARD131,900$769K<0.01%new13F-HRTimeline
Lion Point Capital, LP128,650$750K3.88%-34,10013F-HRTimeline
INTECH INVESTMENT MANAGEMENT LLC124,381$725K0.01%+11,07413F-HRTimeline
Man Group plcin group Man Group plc124,211$724K<0.01%-70,72113F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL123,410$719K<0.01%-1,52913F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd119,643$698K0.02%new13F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…119,103$694K<0.01%-18,19913F-HRTimelineGroup
Caption Management, LLC115,000$670K0.03%new13F-HRTimeline
Pavaki Capital Management LLC115,000$670K0.47%13F-HR/ATimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC113,270$656K<0.01%+87,32813F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …110,220$643K<0.01%-6,47613F-HRTimelineGroup
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…110,048$642K0.17%-9,41313F-HRTimelineGroup
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…100,087$584K<0.01%-2,47913F-HRTimelineGroup
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC98,815$582K<0.01%+11,31713F-HR/ATimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO98,424$574K<0.01%-2,98413F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…95,934$559K<0.01%+11,98713F-HRTimeline
CWM, LLCin group CWM, LLC92,449$539K<0.01%-21,78213F-HRTimelineGroup
Dynamic Technology Lab Private Ltd81,845$477K0.11%-78,49113F-HRTimeline
Inspire Investing, LLCin group Inspire Investing, LLC79,809$465K0.04%-1,78913F-HRTimelineGroup
GK Wealth Management LLC74,568$435K0.32%new13F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC81,128$406K<0.01%new13F-HRTimeline
Brevan Howard Capital Management LPin group Brevan Howard Capital Managem…69,423$405K0.01%new13F-HRTimelineGroup
ARIZONA STATE RETIREMENT SYSTEM67,989$396K<0.01%-2,75113F-HRTimeline
WEALTH ENHANCEMENT ADVISORY SERVICES, L…69,447$386K<0.01%-2,97813F-HRTimeline
Police & Firemen's Retirement System of…65,211$380K<0.01%013F-HRTimeline
Quadrature Capital Ltdin group Quadrature Capital Ltd63,566$371K<0.01%new13F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC61,816$360K<0.01%+10,53713F-HRTimelineGroup
GSA CAPITAL PARTNERS LLP61,148$356K0.03%-32,11213F-HRTimeline
STATE BOARD OF ADMINISTRATION OF FLORID…60,780$354K<0.01%013F-HRTimeline
Persistent Asset Partners Ltd60,490$353K0.17%-31,55613F-HRTimeline
Cerity Partners LLCin group Cerity Partners LLC59,359$346K<0.01%+2,97213F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND59,144$345K<0.01%-16,60013F-HRTimeline
Vise Technologies, Inc.57,638$336K0.01%new13F-HRTimeline
Root Financial Partners, LLC57,539$335K0.02%013F-HRTimeline
ExodusPoint Capital Management, LP55,731$325K<0.01%-79,12513F-HRTimeline
ProShare Advisors LLC54,531$318K<0.01%+5,59513F-HRTimeline
Campbell & CO Investment Adviser LLC53,289$311K0.01%new13F-HRTimeline
Lighthouse Investment Partners, LLCin group Lighthouse Investment Partner…53,006$309K0.01%new13F-HRTimelineGroup
KLP KAPITALFORVALTNING AS51,600$301K<0.01%+1,50013F-HRTimeline
LAZARD ASSET MANAGEMENT LLCin group LAZARD ASSET MANAGEMENT LLC45,257$264K<0.01%+24,67613F-HRTimelineGroup
VARCOV Co.45,004$262K0.1%13F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC42,860$250K<0.01%013F-HRTimelineGroup
VIRGINIA RETIREMENT SYSTEMS ET Al41,750$243K<0.01%+16,55013F-HRTimeline
AXQ CAPITAL, LP40,139$234K0.05%new13F-HRTimeline
China Universal Asset Management Co., L…39,593$231K0.02%-2,64813F-HRTimeline
MERCER GLOBAL ADVISORS INC /ADV38,512$225K<0.01%+1,72213F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS35,686$208K<0.01%-22,93213F-HRTimeline
Mariner, LLCin group Mariner, LLC35,442$206K<0.01%-3,05813F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC33,350$194K<0.01%-5,68213F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…32,479$189K<0.01%013F-HRTimelineGroup
SIG BROKERAGE, LP31,891$186K0.06%013F-HRTimeline
CRUX WEALTH ADVISORS30,973$181K0.07%+3,03513F-HRTimeline
FOX RUN MANAGEMENT, L.L.C.29,362$171K0.03%-19,54213F-HRTimeline
OXFORD ASSET MANAGEMENT LLP29,225$170K0.06%-122,55713F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
Creative Planningin group Creative Planning28,436$166K<0.01%+3,17113F-HRTimelineGroup
Pallas Capital Advisors LLC27,884$163K0.01%-4013F-HRTimeline
STRS OHIO27,500$160K<0.01%013F-HRTimeline
STIFEL FINANCIAL CORPin group STIFEL FINANCIAL CORP27,455$160K<0.01%new13F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…27,116$158K<0.01%-8813F-HRTimelineGroup
VICTORY CAPITAL MANAGEMENT INC26,883$157K<0.01%+14113F-HRTimeline
CreativeOne Wealth, LLCin group CreativeOne Wealth, LLC25,793$150K<0.01%-3,55013F-HRTimelineGroup
Focus Partners Wealthin group Focus Partners Wealth24,692$144K<0.01%+4,60013F-HRTimelineGroup
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…24,496$143K<0.01%013F-HRTimeline
BLAIR WILLIAM & CO/IL24,507$143K<0.01%+713F-HRTimeline
Merit Financial Group, LLC24,250$141K<0.01%+57013F-HRTimeline
FARALLON CAPITAL MANAGEMENT, L.L.C.23,000$134K<0.01%013F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
DCF Advisers, LLC20,000$117K0.04%+10,00013F-HRTimeline
CAPTRUST FINANCIAL ADVISORS19,947$116K<0.01%-1,89613F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…19,715$115K<0.01%013F-HRTimelineGroup
XPONANCE LLC18,947$110K<0.01%+46813F-HRTimeline
NewEdge Advisors, LLC17,909$104K<0.01%+16,90913F-HRTimeline
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co17,670$103K<0.01%-44,25213F-HRTimelineGroup
Ensign Peak Advisors, Inc17,500$102K<0.01%-38,15013F-HR/ATimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management17,222$100K<0.01%-301,22313F-HRTimelineGroup
Orion Porfolio Solutions, LLC16,305$95.1K<0.01%-25713F-HRTimeline
CIBC WORLD MARKETS CORPin group CIBC Bancorp USA Inc.15,854$92.4K<0.01%13F-HRTimelineGroup
Abel Hall, LLC15,847$92.4K0.02%new13F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCgroup of 2 filers holding14,317$83.5K-4,151Timeline
Steward Partners Investment Advisory, L…14,021$81.7K<0.01%+6,29313F-HRTimeline
Sargent Investment Group, LLC14,000$81.6K0.01%new13F-HRTimeline
WINTON GROUP Ltdin group WINTON GROUP Ltd13,500$78.7K<0.01%new13F-HRTimelineGroup
CHICAGO TRUST Co NA13,200$77K0.01%013F-HRTimeline
State of Wyoming12,701$74K0.01%new13F-HRTimeline
Integrated Wealth Concepts LLC12,061$70.3K<0.01%-3,20213F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.11,805$68.8K<0.01%-4,81013F-HRTimelineGroup
Swiss Life Asset Management Ltdin group Swiss Life Asset Management L…11,579$67.5K<0.01%+1,25113F-HRTimelineGroup
Vontobel Holding Ltd.in group Vontobel Holding Ltd.11,470$66.9K<0.01%013F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC11,128$64.9K<0.01%+83013F-HRTimelineGroup
TWO SIGMA SECURITIES, LLC11,001$64.1K0.01%new13F-HRTimeline
Cambridge Investment Research Advisors,…10,930$64K<0.01%new13F-HRTimeline
R Squared Ltd10,788$62.9K0.03%-55213F-HRTimeline
Sumitomo Mitsui Trust Group, Inc.in group Sumitomo Mitsui Trust Group, …10,320$60.2K<0.01%new13F-HRTimelineGroup
KBC Group NVin group KBC Group NV10,361$60K<0.01%013F-HRTimelineGroup
Quantinno Capital Management LP10,282$59.9K<0.01%new13F-HRTimeline
SBI Securities Co., Ltd.10,275$59.9K<0.01%+2213F-HRTimeline
Palisades Investment Partners, LLC10,147$59.2K0.02%013F-HRTimeline
Cyndeo Wealth Partners, LLC10,000$58.3K<0.01%013F-HRTimeline
FIRST HORIZON CORP7,906$46.1K<0.01%+4,31913F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA7,831$46K<0.01%-906,49813F-HRTimelineGroup
AMALGAMATED BANK7,529$44K<0.01%-59313F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…6,677$38.9K<0.01%-3,00413F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…5,436$31.7K<0.01%-35413F-HRTimelineGroup
HighMark Wealth Management LLC4,985$29.1K0.01%013F-HRTimeline
GF FUND MANAGEMENT CO. LTD.4,774$27.8K<0.01%-41113F-HRTimeline
MAI Capital Management3,047$17.8K<0.01%new13F-HRTimeline
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …2,970$17K<0.01%+84213F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC2,846$16.6K<0.01%-75313F-HRTimeline
Allworth Financial LP2,815$16.4K<0.01%-45713F-HRTimeline
Kemnay Advisory Services Inc.2,621$15.3K<0.01%new13F-HRTimeline
Essential Partners LLC2,568$15K<0.01%-17413F-HRTimeline
WEBSTER BANK, N. A.2,000$11.7K<0.01%013F-HRTimeline
IFP Advisors, Inc1,798$10.5K<0.01%-1413F-HRTimeline
Sterling Capital Management LLC1,568$9.14K<0.01%+99613F-HRTimeline
Truvestments Capital LLC1,530$8.92K<0.01%013F-HRTimeline
Torren Management, LLC1,419$8.27K<0.01%13F-HRTimeline
Sound Income Strategies, LLC1,193$8.05K<0.01%new13F-HRTimeline
BROWN BROTHERS HARRIMAN & COin group BROWN BROTHERS HARRIMAN & CO1,147$6.69K<0.01%+75313F-HRTimelineGroup
Garner Asset Management Corp1,000$5.83K<0.01%new13F-HRTimeline