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Disclosery

ARDX ARDELYX INC

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COM (common), issuer CIK 1437402

219 managers (223 13F filers) reported a position in ARDX shares at 2025-09-30, 162,516,164 shares in all. 38 filers opened a position and 20 filers sold out during the quarter.

Managers
219
13F filers
223
New
38
Added
78
Reduced
73
Sold out
20
Shares held by filers
162,516,164

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
BlackRock, Inc.in group BlackRock, Inc.20,823,580$115M<0.01%+75,72713F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC18,369,321$101M<0.01%+2,337,67213F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson13,824,093$76.1M0.03%-1,233,84713F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources756,131$70.9M0.02%+669,01713F-HRTimelineGroup
MACQUARIE GROUP LTDin group MACQUARIE GROUP LTD10,455,588$57.6M0.07%-1,001,96913F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP9,718,690$53.5M<0.01%-123,18113F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP8,943,042$49.3M0.05%-2,307,61013F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC7,641,987$42.1M0.03%-4,021,24213F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC5,756,786$31.7M<0.01%+90,69813F-HRTimelineGroup
Nuveen, LLCin group TIAA5,174,953$28.5M0.01%+1,685,00913F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding4,105,448$22.6M+847,485Timeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.3,313,050$18.3M0.01%+854,38413F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY2,885,340$15.9M<0.01%+541,73513F-HR/ATimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/2,654,197$14.6M<0.01%-2,873,79113F-HR/ATimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC2,584,877$14.2M<0.01%-1,418,65913F-HRTimelineGroup
Rock Springs Capital Management LP2,286,273$12.6M0.74%013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co2,194,754$12.1M<0.01%-2,09413F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC2,193,725$12.1M0.01%+1,425,53313F-HRTimelineGroup
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC2,144,124$11.8M0.01%-168,23913F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP2,117,992$11.7M<0.01%-3,18013F-HRTimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP1,873,903$10.4M0.01%+30,71613F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC1,690,093$9.31M0.01%+388,90013F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC1,528,532$8.42M0.01%-682,72813F-HRTimelineGroup
ORACLE INVESTMENT MANAGEMENT INC1,503,826$8.29M5.78%+73,09813F-HRTimeline
Eversept Partners, LP1,429,377$7.88M0.6%new13F-HRTimeline
Walleye Capital LLCin group Walleye Capital LLC1,211,071$6.67M0.05%+1,197,47813F-HRTimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO1,003,289$5.53M<0.01%+754,36213F-HR/ATimelineGroup
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA914,329$5.04M<0.01%+848,36013F-HRTimelineGroup
Aberdeen Group plcin group Aberdeen Group plc865,596$4.77M0.01%-246,88013F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS865,258$4.77M<0.01%+823,81013F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding831,429$4.58M-690,744Timeline
Hennion & Walsh Asset Management, Inc.780,348$4.3M0.16%+9,99113F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp739,388$4.07M<0.01%+14,22313F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC728,642$4.01M<0.01%-164,06513F-HR/ATimelineGroup
HRT FINANCIAL LP667,082$3.67M0.01%new13F-HRTimeline
PANAGORA ASSET MANAGEMENT INC659,687$3.63M0.01%-69213F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…620,005$3.42M<0.01%-325,27913F-HRTimelineGroup
ARROWSTREET CAPITAL, LIMITED PARTNERSHIPin group ARROWSTREET CAPITAL, LIMITED …579,023$3.19M<0.01%new13F-HRTimelineGroup
Cubist Systematic Strategies, LLC569,831$3.14M0.04%new13F-HRTimeline
Trexquant Investment LP504,328$2.78M0.03%-271,85913F-HRTimeline
CAPITAL FUND MANAGEMENT S.A.495,353$2.73M0.03%-220,76913F-HRTimeline
Swiss National Bank463,900$2.56M<0.01%+5,00013F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC449,215$2.48M<0.01%+74,51513F-HRTimelineGroup
Pekin Hardy Strauss, Inc.402,230$2.22M0.22%-61,20013F-HRTimeline
Freestone Grove Partners LP401,755$2.21M0.02%+244,36413F-HRTimeline
DIADEMA PARTNERS LP400,000$2.2M1.54%new13F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC396,820$2.19M<0.01%+216,10913F-HRTimelineGroup
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …345,077$1.9M<0.01%+22,55713F-HRTimelineGroup
RHUMBLINE ADVISERS340,888$1.88M<0.01%-8,24513F-HRTimeline
Clay Northam Wealth Management, LLC323,465$1.78M1.02%-18,25013F-HRTimeline
Balyasny Asset Management L.P.in group Balyasny Asset Management318,445$1.75M<0.01%-751,41113F-HRTimelineGroup
Rafferty Asset Management, LLC314,781$1.73M0.01%-44,71813F-HRTimeline
Y-Intercept (Hong Kong) Ltd306,547$1.69M0.04%+254,41713F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc269,141$1.48M<0.01%-6,20313F-HRTimelineGroup
ALLIANCEBERNSTEIN L.P.267,340$1.47M<0.01%+3,50013F-HRTimeline
Invesco Ltd.in group Invesco Ltd.257,813$1.42M<0.01%+28,13713F-HRTimelineGroup
IEQ CAPITAL, LLC254,401$1.4M<0.01%+58,29013F-HRTimeline
STATE OF WISCONSIN INVESTMENT BOARD245,138$1.35M<0.01%-115,08113F-HRTimeline
Engineers Gate Manager LP240,390$1.32M0.02%+149,15613F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/227,320$1.25M<0.01%+20,06913F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…217,643$1.2M<0.01%+1113F-HRTimeline
SIMPLEX TRADING, LLC209,233$1.15M0.03%+79,55213F-HRTimeline
MONIMUS CAPITAL MANAGEMENT, LP202,311$1.11M0.83%013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN201,237$1.11M<0.01%+24,88313F-HRTimelineGroup
Stonepine Capital Management, LLC200,000$1.1M0.9%-355,00013F-HRTimeline
AIGH Capital Management LLC198,500$1.09M0.38%new13F-HRTimeline
Man Group plcin group Man Group plc194,932$1.07M<0.01%-32,76613F-HRTimelineGroup
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\193,996$1.07M<0.01%+23,43013F-HRTimelineGroup
FIRST TRUST ADVISORS LPin group FIRST TRUST ADVISORS LP182,600$1.01M<0.01%-152,99713F-HRTimelineGroup
MACKENZIE FINANCIAL CORP176,835$974K<0.01%-44,04513F-HRTimeline
Arax Advisory Partners167,299$922K0.01%new13F-HRTimeline
NOMURA HOLDINGS INCin group NOMURA ASSET MANAGEMENT CO LTD165,992$915K<0.01%new13F-HRTimelineGroup
Schonfeld Strategic Advisors LLC162,800$897K0.01%-155,91313F-HRTimeline
Lion Point Capital, LP162,750$897K5.09%-172,65013F-HRTimeline
LPL Financial LLC162,064$893K<0.01%+35,42313F-HRTimeline
Dynamic Technology Lab Private Ltd160,336$883K0.15%+30,01513F-HRTimeline
Thrivent Financial for Lutheransin group Thrivent Financial for Luther…156,428$862K<0.01%-49,01613F-HRTimelineGroup
OXFORD ASSET MANAGEMENT LLP151,782$836K0.28%+130,91813F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
PFG Investments, LLC138,295$762K0.04%+5,00013F-HRTimeline
MetLife Investment Management, LLCin group MetLife Investment Management…137,302$757K<0.01%new13F-HRTimelineGroup
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding135,043$746K-21,293Timeline
ExodusPoint Capital Management, LP134,856$743K0.01%-109,33513F-HRTimeline
SG Americas Securities, LLC131,925$727K<0.01%+110,45913F-HRTimeline
TUDOR INVESTMENT CORP ET AL124,939$688K<0.01%new13F-HR/ATimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…119,461$658K0.19%013F-HRTimelineGroup
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …116,696$643K<0.01%-4,38613F-HRTimelineGroup
CAPSTONE INVESTMENT ADVISORS, LLCin group CAPSTONE INVESTMENT ADVISORS,…115,814$638K0.01%new13F-HRTimelineGroup
CWM, LLCin group CWM, LLC114,231$629K<0.01%+33,97313F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC113,307$624K0.01%-53,22213F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…102,566$565K<0.01%+4,96713F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO101,408$559K<0.01%+81,73013F-HRTimelineGroup
DekaBank Deutsche Girozentrale100,000$558K<0.01%013F-HRTimeline
HARBOR CAPITAL ADVISORS, INC.100,108$552K0.04%-133,14013F-HRTimeline
GSA CAPITAL PARTNERS LLP93,260$514K0.04%-47,69713F-HRTimeline
GROUP ONE TRADING LLC93,271$514K0.02%-195,69013F-HRTimeline
Persistent Asset Partners Ltd92,046$507K0.37%new13F-HR/ATimeline
Headlands Technologies LLC91,167$502K0.04%new13F-HRTimeline
J. Goldman & Co LP90,500$499K0.02%-155,41713F-HRTimeline
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC89,982$496K<0.01%-115,47413F-HRTimelineGroup
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC87,498$489K<0.01%-17,85113F-HRTimelineGroup
ALGERT GLOBAL LLC85,736$472K0.01%-1,252,70213F-HR/ATimeline
Zurcher Kantonalbank (Zurich Cantonalba…83,947$463K<0.01%013F-HRTimeline
Inspire Investing, LLCin group Inspire Investing, LLC81,598$450K0.04%-16,93113F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND75,744$417K<0.01%-172,80013F-HRTimeline
ARIZONA STATE RETIREMENT SYSTEM70,740$390K<0.01%+1,17813F-HRTimeline
PROFUND ADVISORS LLC69,262$382K0.01%-6,58913F-HRTimeline
WEALTH ENHANCEMENT ADVISORY SERVICES, L…72,425$374K<0.01%+7,39513F-HRTimeline
Henshaw Capital LLC65,757$362K0.01%-24,50313F-HRTimeline
Police & Firemen's Retirement System of…65,211$359K<0.01%+13,33713F-HRTimeline
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co61,922$349K<0.01%013F-HRTimelineGroup
STATE BOARD OF ADMINISTRATION OF FLORID…60,780$335K<0.01%013F-HRTimeline
WOLVERINE TRADING, LLC59,274$334K0.01%new13F-HRTimeline
IMC-Chicago, LLC58,759$324K0.01%new13F-HRTimeline
TEACHER RETIREMENT SYSTEM OF TEXAS58,618$323K<0.01%-5,61813F-HRTimeline
Root Financial Partners, LLC57,539$317K0.02%013F-HRTimeline
Cerity Partners LLCin group Cerity Partners LLC56,387$311K<0.01%-49,13913F-HRTimelineGroup
Ensign Peak Advisors, Inc55,650$307K<0.01%-27,15013F-HR/ATimeline
CITIGROUP INCin group CITIGROUP INC51,279$283K<0.01%-113,96613F-HRTimelineGroup
KLP KAPITALFORVALTNING AS50,100$276K<0.01%013F-HRTimeline
ProShare Advisors LLC48,936$270K<0.01%-8,38813F-HRTimeline
FOX RUN MANAGEMENT, L.L.C.48,904$269K0.04%new13F-HRTimeline
V. M. MANNING & CO., INC.41,558$262K0.24%new13F-HRTimeline
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC42,860$236K<0.01%-22,02913F-HRTimelineGroup
Voleon Capital Management LP42,259$233K0.01%new13F-HRTimeline
China Universal Asset Management Co., L…42,241$233K0.02%-5,81213F-HRTimeline
COMMONWEALTH EQUITY SERVICES, LLC39,032$215K<0.01%+1,00013F-HRTimeline
Mariner, LLCin group Mariner, LLC38,500$212K<0.01%+19,54713F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC37,600$207K<0.01%new13F-HR/ATimelineGroup
MERCER GLOBAL ADVISORS INC /ADV36,790$203K<0.01%+22,82713F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…32,479$179K<0.01%013F-HRTimelineGroup
SIG BROKERAGE, LP31,891$176K0.04%013F-HRTimeline
CreativeOne Wealth, LLCin group CreativeOne Wealth, LLC29,343$162K<0.01%-8,17513F-HRTimelineGroup
CRUX WEALTH ADVISORS27,938$154K0.06%+54513F-HRTimeline
Pallas Capital Advisors LLC27,924$154K0.01%+96213F-HRTimeline
STRS OHIO27,500$152K<0.01%013F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…27,204$150K<0.01%-117,31213F-HRTimelineGroup
VICTORY CAPITAL MANAGEMENT INC26,742$147K<0.01%-44,40813F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC25,942$141K<0.01%new13F-HRTimelineGroup
Creative Planningin group Creative Planning25,265$139K<0.01%+12,92313F-HRTimelineGroup
VIRGINIA RETIREMENT SYSTEMS ET Al25,200$139K<0.01%new13F-HRTimeline
CIBC Bancorp USA Inc.in group CIBC Bancorp USA Inc.25,155$139K<0.01%13F-HR/ATimelineGroup
Focus Partners Wealthin group Focus Partners Wealth20,092$135K<0.01%+6,15713F-HRTimelineGroup
PUBLIC EMPLOYEES RETIREMENT ASSOCIATION…24,496$135K<0.01%013F-HRTimeline
BLAIR WILLIAM & CO/IL24,500$135K<0.01%013F-HRTimeline
Quantbot Technologies LP24,148$133K<0.01%new13F-HRTimeline
Merit Financial Group, LLC23,680$130K<0.01%+2,53713F-HR/ATimeline
FARALLON CAPITAL MANAGEMENT, L.L.C.23,000$127K<0.01%013F-HR/ATimeline
CAPTRUST FINANCIAL ADVISORS21,843$120K<0.01%+9,94213F-HRTimeline
FMR LLCin group FMR LLC21,391$118K<0.01%-38,17113F-HRTimelineGroup
Aigen Investment Management, LP21,365$118K0.02%new13F-HRTimeline
LAZARD ASSET MANAGEMENT LLCin group LAZARD ASSET MANAGEMENT LLC20,581$113K<0.01%+15,92613F-HRTimelineGroup
Ameritas Investment Partners, Inc.group of 2 filers holding19,715$109K-15,404Timeline
EntryPoint Capital, LLC18,653$103K0.04%-76,46013F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.16,615$103K<0.01%-23913F-HRTimelineGroup
XPONANCE LLC18,479$102K<0.01%+20313F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCgroup of 2 filers holding18,468$102K+1,485Timeline
Orion Porfolio Solutions, LLC16,562$91.3K<0.01%+16813F-HRTimeline
Integrated Wealth Concepts LLC15,263$84.1K<0.01%+2,97513F-HRTimeline
Polymer Capital Management (US) LLC14,662$80.8K0.01%-10,44513F-HRTimeline
Jain Global LLC13,500$74.4K<0.01%new13F-HRTimeline
CHICAGO TRUST Co NA13,200$72.7K0.01%new13F-HRTimeline
Virtu Financial LLCin group Virtu Financial LLC12,998$72K<0.01%-99013F-HRTimelineGroup
BRIGHTON JONES LLC12,701$70K<0.01%+2,55013F-HRTimeline
Vontobel Holding Ltd.in group Vontobel Holding Ltd.11,470$63.2K<0.01%new13F-HRTimelineGroup
Sheets Smith Investment Management11,393$62.8K0.04%013F-HRTimeline
R Squared Ltd11,340$62.5K0.03%new13F-HRTimeline
KBC Group NVin group KBC Group NV10,361$57K<0.01%+5,43213F-HRTimelineGroup
Swiss Life Asset Management Ltdin group Swiss Life Asset Management L…10,328$56.9K<0.01%new13F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC10,298$56.7K<0.01%-18513F-HRTimelineGroup
SBI Securities Co., Ltd.10,253$56.5K<0.01%+6,10213F-HRTimeline
Palisades Investment Partners, LLC10,147$55.9K0.02%-511,09313F-HRTimeline
DCF Advisers, LLC10,000$55.1K0.02%013F-HRTimeline
Cyndeo Wealth Partners, LLC10,000$55.1K<0.01%013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…9,681$53.3K<0.01%-15,30813F-HRTimelineGroup
AMALGAMATED BANK8,122$45K<0.01%013F-HRTimeline
Steward Partners Investment Advisory, L…7,728$42.6K<0.01%-2,00013F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…5,790$31.9K<0.01%+1,01613F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.5,185$28.6K<0.01%-87913F-HRTimeline
HighMark Wealth Management LLC4,985$27.5K0.01%013F-HRTimeline
Point72 (DIFC) Ltd4,610$25.4K<0.01%new13F-HRTimeline
NISA INVESTMENT ADVISORS, LLC3,599$19.8K<0.01%+75513F-HRTimeline
FIRST HORIZON CORP3,587$19.8K<0.01%13F-HRTimeline
Allworth Financial LP3,272$18K<0.01%+1,68513F-HRTimeline
Essential Partners LLC2,742$15.1K<0.01%+67213F-HRTimeline
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …2,128$12K<0.01%+21213F-HRTimelineGroup
WEBSTER BANK, N. A.2,000$11K<0.01%013F-HRTimeline
IFP Advisors, Inc1,812$9.98K<0.01%013F-HR/ATimeline
Clearstead Advisors, LLC1,793$9.88K<0.01%+17713F-HRTimeline
Truvestments Capital LLC1,530$8.43K<0.01%-1,36113F-HRTimeline
Quarry LP1,433$7.9K<0.01%new13F-HRTimeline
Optiver Holding B.V.in group Optiver Holding B.V.1,272$7.01K<0.01%+713F-HRTimelineGroup
Wealthspire Advisors, LLC1,193$6.57K<0.01%new13F-HRTimeline
NewEdge Advisors, LLC1,000$5.51K<0.01%013F-HRTimeline
COMERICA BANK985$5.43K<0.01%-5113F-HRTimeline
Aster Capital Management (DIFC) Ltd966$5.32K<0.01%new13F-HRTimeline
Parallel Advisors, LLC835$4.6K<0.01%013F-HRTimeline
Larson Financial Group LLC819$4.51K<0.01%+52213F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.754$4K<0.01%013F-HRTimelineGroup
Aventura Private Wealth, LLC672$3.7K<0.01%013F-HRTimeline
Sterling Capital Management LLC572$3.15K<0.01%+2413F-HRTimeline