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Paradigm Biocapital Advisors LP: SYRE position timeline

Available 13F reports, 13D and 13G stakes and each Form 3, 4 and 5 line of Paradigm Biocapital Advisors LP on SYRE, newest first. How the timeline and the estimate are built.

Paradigm Biocapital Advisors LP held 3,840,778 SYRE shares at 2026-06-30 per its 13F-HR filed 2026-08-14, and reported 4,457,450 shares, 5.1%, in a 13G filed 2026-10-01.

Estimated current stake: 4,457,450 shares, 5.1% of the class

Estimated from 13G of 2026-10-01. As of 2026-09-24, 13G 0001104659-26-112828.

Shares are the reporting group's aggregate and may include entities that do not file a 13F.

The reporting persons may hold separate positions, so the group total can be higher than the largest row.

Percent of portfolio stays on the 13F for 2026-06-30.

  1. event date2026-09-24
    13G 4,457,450 shares
    Share basis changed not comparable

    5.1% of the class. Different basis (group aggregate from 13G).

    13G 0001104659-26-112828 filed by Paradigm Biocapital Advisors LP
    Accepted , ingested

    A 13D/G states the aggregate of its reporting persons, which may include entities that do not file a 13F.

    The reporting persons may hold separate positions, so the group total can be higher than the largest row.

  2. period ended2026-06-30
    13F 3,840,778 shares
    Change vs previous 13F +1,883,512 shares

    6.38% of the 13F portfolio, value $340,984,271.

    13F-HR 0001855655-26-000014 filed by Paradigm Biocapital Advisors LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  3. period ended2026-03-31
    13F 1,957,266 shares
    Change vs previous 13F +490,000 shares

    2.02% of the 13F portfolio, value $98,724,497.

    13F-HR 0001855655-26-000011 filed by Paradigm Biocapital Advisors LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  4. period ended2025-12-31
    13F 1,467,266 shares
    Change vs previous 13F 0 shares

    1.29% of the 13F portfolio, value $48,067,634.

    13F-HR 0001855655-26-000003 filed by Paradigm Biocapital Advisors LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  5. period ended2025-09-30
    13F 1,467,266 shares
    Change vs previous 13F -403,179 shares

    0.73% of the 13F portfolio, value $24,591,378.

    13F-HR 0001855655-25-000014 filed by Paradigm Biocapital Advisors LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  6. period ended2025-06-30
    13F 1,870,445 shares
    Change vs previous 13F -256,760 shares

    1.2% of the 13F portfolio, value $28,000,562.

    13F-HR 0001855655-25-000010 filed by Paradigm Biocapital Advisors LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  7. period ended2025-03-31
    13F 2,127,205 shares
    Change vs previous 13F +600,000 shares

    1.58% of the 13F portfolio, value $34,322,453.

    13F-HR 0001855655-25-000007 filed by Paradigm Biocapital Advisors LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  8. period ended2024-12-31
    13F 1,527,205 shares
    Change vs previous 13F +259,624 shares

    1.24% of the 13F portfolio, value $35,553,332.

    13F-HR 0001855655-25-000004 filed by Paradigm Biocapital Advisors LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).

  9. period ended2024-09-30
    13F 1,267,581 shares
    Change vs previous 13F not available

    1.3% of the 13F portfolio, value $37,279,557.

    13F-HR 0001855655-24-000014 filed by Paradigm Biocapital Advisors LP
    Filed (acceptance time not in the bulk data set), ingested

    Acceptance time not in the bulk data set (spec §4.2).