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Disclosery

TNYA TENAYA THERAPEUTICS INC

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COM (common), issuer CIK 1858848

96 managers (98 13F filers) reported a position in TNYA shares at 2025-12-31, 68,610,982 shares in all. 22 filers opened a position and 18 filers sold out during the quarter.

Managers
96
13F filers
98
New
22
Added
30
Reduced
20
Sold out
18
Shares held by filers
68,610,982

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
Column Group LLC9,400,290$6.69M8.08%013F-HRTimeline
VANGUARD GROUP INCgroup of 2 filers holding8,606,083$6.13M+3,495,400Timeline
Empery Asset Management, LPin group Empery Asset Management, LP5,414,101$3.85M3.4%13F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC4,615,746$3.28M<0.01%+111,15413F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC4,200,000$2.99M<0.01%new13F-HRTimelineGroup
Anson Funds Management LPin group Anson Funds Management LP4,152,966$2.95M0.4%new13F-HRTimelineGroup
Alyeska Investment Group, L.P.in group Alyeska Investment Group, L.P.4,000,000$2.85M0.01%new13F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.3,948,586$2.81M<0.01%+1,621,38513F-HRTimelineGroup
Burkehill Global Management, LP2,000,000$1.42M0.09%new13F-HRTimeline
Kalehua Capital Management LLC2,000,000$1.42M1.41%13F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC1,850,867$1.32M<0.01%+172,66513F-HRTimeline
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding1,660,575$1.18M+536,507Timeline
ADAR1 Capital Management, LLCin group ADAR1 Capital Management, LLC1,505,300$1.07M0.08%new13F-HR/ATimelineGroup
SPHERA FUNDS MANAGEMENT LTD.in group SPHERA FUNDS MANAGEMENT LTD.1,500,000$1.07M0.22%new13F-HRTimelineGroup
GSA CAPITAL PARTNERS LLP1,478,612$1.05M0.09%+1,016,80813F-HRTimeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP1,406,035$998K<0.01%+1,388,75013F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC1,193,355$849K<0.01%+17,82013F-HRTimelineGroup
Euclidean Capital LLC1,015,705$723K0.2%013F-HRTimeline
Alphabet Inc.in group Alphabet Inc.915,705$650K0.03%013F-HRTimelineGroup
Raiffeisen Bank International AGin group Raiffeisen Bank International…900,000$630K0.01%+550,00013F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC678,460$483K<0.01%+522,20513F-HRTimelineGroup
Mirador Capital Partners LP582,524$414K0.06%+559,02413F-HRTimeline
UBS Group AGin group UBS Group AG579,601$413K<0.01%+382,87413F-HRTimelineGroup
StepStone Group LP462,163$328K0.18%013F-HRTimeline
STATE STREET CORPin group STATE STREET CORP445,821$317K<0.01%013F-HRTimelineGroup
Casdin Capital, LLC361,969$258K0.02%013F-HRTimeline
Stonepine Capital Management, LLC352,001$250K0.2%new13F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…284,587$202K<0.01%-70,15213F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP241,580$172K<0.01%+2,09113F-HRTimelineGroup
OMERS ADMINISTRATION Corp236,400$168K<0.01%new13F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY208,431$148K<0.01%+41,34213F-HR/ATimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC194,800$139K<0.01%+175,00013F-HRTimeline
Marex Group Ltdin group Marex Group Ltd185,011$132K<0.01%-117,48913F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC185,001$132K<0.01%+185,00013F-HRTimelineGroup
Graham Capital Management, L.P.178,764$127K<0.01%new13F-HRTimeline
Cetera Investment Advisers106,425$75.7K<0.01%+55,00013F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd105,692$75.2K<0.01%+7,85413F-HRTimelineGroup
Corient Private Wealth LPin group Corient Private Wealth LP100,800$71.7K<0.01%new13F-HR/ATimelineGroup
Lighthouse Investment Partners, LLCin group Lighthouse Investment Partner…87,600$62.3K<0.01%new13F-HRTimelineGroup
JACOBS LEVY EQUITY MANAGEMENT, INC75,927$54K<0.01%new13F-HRTimeline
Deeter Investments LLP75,000$53.4K0.01%13F-HRTimeline
Pathstone Holdings, LLCin group Pathstone Holdings, LLC75,000$53.4K<0.01%013F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP70,478$50.1K<0.01%-2,93013F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC67,977$48.4K<0.01%-159,52013F-HR/ATimelineGroup
Jefferies Financial Group Inc.in group Jefferies Financial Group Inc.58,235$41.4K<0.01%-3,06513F-HRTimelineGroup
Callan Family Office, LLC50,061$35.6K<0.01%+13,79213F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co50,000$35.6K<0.01%013F-HRTimelineGroup
ATTICUS WEALTH MANAGEMENT, LLC43,237$30.8K0.01%-1,62513F-HRTimeline
SIMPLEX TRADING, LLC38,543$27.4K<0.01%-73,38913F-HRTimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.38,475$27.4K<0.01%new13F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.34,400$24.4K<0.01%+40013F-HRTimelineGroup
Virtu Financial LLCin group Virtu Financial LLC32,725$23K<0.01%-11,52413F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/31,453$23K<0.01%013F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/32,075$22.8K<0.01%-9,92313F-HRTimelineGroup
EWA, LLC31,422$22.4K0.01%+1,67513F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC28,748$20.5K<0.01%-130,87113F-HRTimelineGroup
China Universal Asset Management Co., L…27,132$19.3K<0.01%new13F-HRTimeline
CITIGROUP INCin group CITIGROUP INC23,475$16.7K<0.01%+22,63413F-HRTimelineGroup
Mariner, LLCin group Mariner, LLC22,071$15.7K<0.01%+1,67813F-HRTimelineGroup
KESTRA PRIVATE WEALTH SERVICES, LLCin group Kestra Advisory Services, LLC22,000$15.7K<0.01%013F-HRTimelineGroup
Integrated Wealth Concepts LLC21,940$15.6K<0.01%-9213F-HRTimeline
HighPoint Advisor Group LLC21,300$15.2K<0.01%-30,20013F-HRTimeline
World Investment Advisors18,787$13.4K<0.01%+5,00013F-HR/ATimeline
CITIZENS FINANCIAL GROUP INC/RIin group CITIZENS FINANCIAL GROUP INC/…18,000$12.8K<0.01%new13F-HRTimelineGroup
VICTORY CAPITAL MANAGEMENT INC17,648$12.6K<0.01%new13F-HRTimeline
Parkwoods Wealth Partners, LLC17,000$12.1K<0.01%+2,00013F-HRTimeline
PRUDENTIAL FINANCIAL INCin group PRUDENTIAL FINANCIAL INC16,200$11.5K<0.01%new13F-HRTimelineGroup
COMMERCE BANKin group COMMERCE BANK15,000$10.7K<0.01%-10,00013F-HRTimelineGroup
Northern Lights Advisors, Inc.14,953$10.6K0.01%13F-HRTimeline
LPL Financial LLC14,823$10.5K<0.01%-7,53013F-HRTimeline
Federation des caisses Desjardins du Qu…14,500$10.3K<0.01%013F-HRTimeline
Legacy Wealth Partners, LLC14,084$10K<0.01%13F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO13,827$9.84K<0.01%+13,30813F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS12,344$8.78K<0.01%+11,50413F-HRTimelineGroup
Aptus Capital Advisors, LLC12,065$8.58K<0.01%013F-HRTimeline
Galvin, Gaustad & Stein, LLC11,000$7.83K<0.01%013F-HRTimeline
Sequoia Financial Advisors, LLC10,725$7.63K<0.01%new13F-HRTimeline
Jasper Ridge Partners, L.P.10,250$7.29K<0.01%013F-HRTimeline
Quadcap Wealth Management, LLC10,000$7.12K<0.01%new13F-HRTimeline
X-Square Capital, LLC10,000$7K<0.01%013F-HRTimeline
GROUP ONE TRADING LLC9,508$6.76K<0.01%-23,19813F-HRTimeline
Mirae Asset Global Investments Co., Ltd.in group Mirae Asset Global Investment…8,091$5.76K<0.01%new13F-HRTimelineGroup
VSM Wealth Advisory, LLC5,000$3.56K<0.01%new13F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA3,705$3K<0.01%-260,65713F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN4,000$2.85K<0.01%+3,00013F-HRTimelineGroup
Torren Management, LLC3,673$2.61K<0.01%13F-HRTimeline
FMR LLCin group FMR LLC2,764$1.97K<0.01%013F-HRTimelineGroup
TFC Financial Management, Inc.2,500$1.78K<0.01%013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC2,252$1.6K<0.01%013F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…1,541$1.1K<0.01%-1,08813F-HRTimelineGroup
CWM, LLCin group CWM, LLC1,559$1K<0.01%-13,08013F-HRTimelineGroup
Farther Finance Advisors, LLC1,000$712<0.01%013F-HRTimeline
SBI Securities Co., Ltd.783$557<0.01%-70113F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP100$71<0.01%new13F-HRTimelineGroup
Optiver Holding B.V.in group Optiver Holding B.V.54$38<0.01%013F-HRTimelineGroup
IFP Advisors, Inc16$11<0.01%-49013F-HRTimeline