Nantahala Capital Management, LLC in group Nantahala Capital Management,… More: the full row for Nantahala Capital Management, LLC 6,376,857 $26.2M 1.64% +556,208 13F-HR Timeline Group BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 4,290,383 $17.6M <0.01% +195,083 13F-HR Timeline Group VANGUARD GROUP INC group of 4 filers holding More: the full row for VANGUARD GROUP INC 3,399,069 $14M new Timeline BRAIDWELL LP More: the full row for BRAIDWELL LP 3,105,209 $12.8M 0.43% 0 13F-HR Timeline Frazier Life Sciences Management, L.P. More: the full row for Frazier Life Sciences Management, L.P. 2,630,665 $10.8M 0.28% 0 13F-HR Timeline Soleus Capital Management, L.P. More: the full row for Soleus Capital Management, L.P. 2,245,360 $9.23M 0.37% +1,175,360 13F-HR Timeline Stonepine Capital Management, LLC More: the full row for Stonepine Capital Management, LLC 1,759,091 $7.23M 6.36% +127,503 13F-HR Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 1,461,159 $6.01M <0.01% -631,878 13F-HR Timeline Group ARMISTICE CAPITAL, LLC More: the full row for ARMISTICE CAPITAL, LLC 1,396,000 $5.74M 0.19% +420,000 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 1,381,338 $5.68M <0.01% -4,910 13F-HR Timeline Group STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 1,320,790 $5.43M <0.01% -254,061 13F-HR Timeline Group PERCEPTIVE ADVISORS LLC in group PERCEPTIVE ADVISORS LLC More: the full row for PERCEPTIVE ADVISORS LLC 1,286,862 $5.29M 0.1% new 13F-HR/A Timeline Group RICE HALL JAMES & ASSOCIATES, LLC More: the full row for RICE HALL JAMES & ASSOCIATES, LLC 1,254,819 $5.16M 0.29% +101,375 13F-HR Timeline PINNACLE ASSOCIATES LTD More: the full row for PINNACLE ASSOCIATES LTD 1,158,895 $4.76M 0.06% +376,530 13F-HR Timeline GOLDMAN SACHS GROUP INC in group GOLDMAN SACHS GROUP INC More: the full row for GOLDMAN SACHS GROUP INC 1,086,398 $4.47M <0.01% +735,656 13F-HR Timeline Group UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 752,881 $3.09M <0.01% -128,488 13F-HR Timeline Group CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 696,629 $2.86M <0.01% -682,502 13F-HR Timeline Group Soviero Asset Management, LP More: the full row for Soviero Asset Management, LP 680,373 $2.8M 1.57% +25,373 13F-HR Timeline AWH Capital, L.P. More: the full row for AWH Capital, L.P. 625,000 $2.57M 2.33% 0 13F-HR Timeline Assenagon Asset Management S.A. More: the full row for Assenagon Asset Management S.A. 598,145 $2.46M <0.01% +327,926 13F-HR Timeline D. E. Shaw & Co., Inc. in group D. E. Shaw & Co., Inc. More: the full row for D. E. Shaw & Co., Inc. 559,050 $2.3M <0.01% -982,046 13F-HR Timeline Group CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 515,516 $2.12M <0.01% -1,613 13F-HR Timeline Group TANG CAPITAL MANAGEMENT LLC in group TANG CAPITAL MANAGEMENT LLC More: the full row for TANG CAPITAL MANAGEMENT LLC 483,021 $1.99M 0.1% -762,671 13F-HR Timeline Group NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 472,343 $1.94M <0.01% +27,177 13F-HR Timeline Group STIFEL FINANCIAL CORP in group STIFEL FINANCIAL CORP More: the full row for STIFEL FINANCIAL CORP 458,396 $1.88M <0.01% +195,267 13F-HR Timeline Group DEUTSCHE BANK AG\ in group DEUTSCHE BANK AG\ More: the full row for DEUTSCHE BANK AG\ 441,655 $1.82M <0.01% +4,908 13F-HR Timeline Group CM Management, LLC More: the full row for CM Management, LLC 400,000 $1.64M 1.37% +150,000 13F-HR Timeline Trexquant Investment LP More: the full row for Trexquant Investment LP 375,210 $1.54M 0.01% +356,372 13F-HR Timeline RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 339,025 $1.39M <0.01% -460,875 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 240,133 $987K <0.01% -490,532 13F-HR Timeline Group Caption Management, LLC More: the full row for Caption Management, LLC 216,316 $889K 0.04% new 13F-HR Timeline AMERICAN ASSETS INC in group American Assets Investment Ma… More: the full row for AMERICAN ASSETS INC 110,000 $883K 0.3% -15,000 13F-HR Timeline Group National Philanthropic Trust More: the full row for National Philanthropic Trust 200,000 $822K 0.01% 0 13F-HR Timeline Squarepoint Ops LLC in group Squarepoint Ops LLC More: the full row for Squarepoint Ops LLC 158,392 $651K <0.01% -15,954 13F-HR Timeline Group Krensavage Asset Management, LLC More: the full row for Krensavage Asset Management, LLC 157,985 $649K 0.25% +57,985 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 155,248 $638K <0.01% -202,798 13F-HR Timeline Group Bank of New York Mellon Corp in group Bank of New York Mellon Corp More: the full row for Bank of New York Mellon Corp 143,164 $588K <0.01% +5,367 13F-HR Timeline Group Potomac Capital Management, Inc. More: the full row for Potomac Capital Management, Inc. 141,500 $582K 0.51% +328 13F-HR Timeline NATIXIS in group Natixis Investment Managers More: the full row for NATIXIS 141,437 $581K <0.01% +140,000 13F-HR Timeline Group Quantinno Capital Management LP More: the full row for Quantinno Capital Management LP 124,761 $513K <0.01% +35,773 13F-HR Timeline Nuveen, LLC in group TIAA More: the full row for Nuveen, LLC 111,602 $459K <0.01% +23,233 13F-HR Timeline Group Campbell & CO Investment Adviser LLC More: the full row for Campbell & CO Investment Adviser LLC 101,867 $419K 0.02% -238,321 13F-HR Timeline ALLIANCEBERNSTEIN L.P. More: the full row for ALLIANCEBERNSTEIN L.P. 62,340 $415K <0.01% 0 13F-HR Timeline Knott David M Jr More: the full row for Knott David M Jr 99,338 $408K 0.24% 0 13F-HR Timeline STATE OF WISCONSIN INVESTMENT BOARD More: the full row for STATE OF WISCONSIN INVESTMENT BOARD 98,285 $404K <0.01% +33,189 13F-HR Timeline PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 97,964 $403K <0.01% +12,600 13F-HR Timeline SUSQUEHANNA INTERNATIONAL GROUP, LLP in group SUSQUEHANNA INTERNATIONAL GRO… More: the full row for SUSQUEHANNA INTERNATIONAL GROUP, LLP 91,509 $376K <0.01% +11,358 13F-HR Timeline Group Corient Private Wealth LP in group Corient Private Wealth LP More: the full row for Corient Private Wealth LP 79,939 $329K <0.01% new 13F-HR Timeline Group Seven Fleet Capital Management LP More: the full row for Seven Fleet Capital Management LP 78,057 $321K 0.1% -3,943 13F-HR/A Timeline WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 74,497 $306K <0.01% -1,471 13F-HR/A Timeline Group XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 69,110 $284K <0.01% +1,119 13F-HR Timeline Group RHUMBLINE ADVISERS More: the full row for RHUMBLINE ADVISERS 68,726 $282K <0.01% -1,323 13F-HR Timeline Russell Investments Group, Ltd. in group Russell Investments Group, Lt… More: the full row for Russell Investments Group, Ltd. 67,366 $277K <0.01% +1,795 13F-HR Timeline Group Man Group plc in group Man Group plc More: the full row for Man Group plc 66,243 $272K <0.01% +22,839 13F-HR Timeline Group Aquatic Capital Management LLC More: the full row for Aquatic Capital Management LLC 59,796 $246K 0.01% +31,413 13F-HR Timeline ADAR1 Capital Management, LLC in group ADAR1 Capital Management, LLC More: the full row for ADAR1 Capital Management, LLC 55,859 $230K 0.01% +20,000 13F-HR Timeline Group FULLER & THALER ASSET MANAGEMENT, INC. More: the full row for FULLER & THALER ASSET MANAGEMENT, INC. 55,513 $228K <0.01% new 13F-HR Timeline LPL Financial LLC More: the full row for LPL Financial LLC 54,651 $225K <0.01% -6,324 13F-HR Timeline PRELUDE CAPITAL MANAGEMENT, LLC More: the full row for PRELUDE CAPITAL MANAGEMENT, LLC 51,303 $211K 0.02% +12,000 13F-HR Timeline Headlands Technologies LLC More: the full row for Headlands Technologies LLC 48,823 $201K 0.02% new 13F-HR Timeline AXQ CAPITAL, LP More: the full row for AXQ CAPITAL, LP 47,670 $196K 0.03% new 13F-HR Timeline Pathstone Holdings, LLC in group Pathstone Holdings, LLC More: the full row for Pathstone Holdings, LLC 45,259 $186K <0.01% +4,200 13F-HR Timeline Group Invesco Ltd. in group Invesco Ltd. More: the full row for Invesco Ltd. 36,335 $149K <0.01% +2,216 13F-HR Timeline Group HSBC HOLDINGS PLC in group HSBC HOLDINGS PLC More: the full row for HSBC HOLDINGS PLC 34,288 $142K <0.01% new 13F-HR Timeline Group State of Wyoming More: the full row for State of Wyoming 31,016 $127K 0.02% +21,519 13F-HR Timeline AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 30,635 $126K <0.01% -23,635 13F-HR/A Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 31,476 $124K <0.01% -194,126 13F-HR/A Timeline Group Mirae Asset Global Investments Co., Ltd. group of 2 filers holding More: the full row for Mirae Asset Global Investments Co., Ltd. 29,705 $122K +2,429 Timeline Creative Planning in group Creative Planning More: the full row for Creative Planning 28,737 $118K <0.01% +4,677 13F-HR Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 27,878 $115K <0.01% -102,860 13F-HR Timeline Group SEI INVESTMENTS CO in group SEI INVESTMENTS CO More: the full row for SEI INVESTMENTS CO 25,947 $107K <0.01% -19,554 13F-HR Timeline Group AQR CAPITAL MANAGEMENT LLC in group AQR CAPITAL MANAGEMENT LLC More: the full row for AQR CAPITAL MANAGEMENT LLC 25,677 $106K <0.01% +2,700 13F-HR Timeline Group BENDER ROBERT & ASSOCIATES More: the full row for BENDER ROBERT & ASSOCIATES 25,070 $103K 0.02% new 13F-HR Timeline Chicago Partners Investment Group LLC More: the full row for Chicago Partners Investment Group LLC 19,291 $100K <0.01% new 13F-HR Timeline Quadrature Capital Ltd in group Quadrature Capital Ltd More: the full row for Quadrature Capital Ltd 24,068 $98.9K <0.01% +5,973 13F-HR Timeline Group MetLife Investment Management, LLC in group MetLife Investment Management… More: the full row for MetLife Investment Management, LLC 18,307 $75.2K <0.01% -10,081 13F-HR Timeline Group Pure Financial Advisors, LLC More: the full row for Pure Financial Advisors, LLC 17,995 $74K <0.01% +195 13F-HR Timeline MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 17,900 $73.6K <0.01% new 13F-HR Timeline Group SG Americas Securities, LLC More: the full row for SG Americas Securities, LLC 16,763 $69K <0.01% -11,064 13F-HR Timeline Federation des caisses Desjardins du Qu… More: the full row for Federation des caisses Desjardins du Quebec 16,680 $68.6K <0.01% +10,483 13F-HR Timeline MANUFACTURERS LIFE INSURANCE COMPANY, T… in group MANUFACTURERS LIFE INSURANCE … More: the full row for MANUFACTURERS LIFE INSURANCE COMPANY, THE 16,219 $66.7K <0.01% -13 13F-HR Timeline Group Police & Firemen's Retirement System of… More: the full row for Police & Firemen's Retirement System of New Jersey 15,833 $65.1K <0.01% 0 13F-HR Timeline INTECH INVESTMENT MANAGEMENT LLC More: the full row for INTECH INVESTMENT MANAGEMENT LLC 15,449 $63.5K <0.01% -17,240 13F-HR Timeline OneDigital Investment Advisors LLC More: the full row for OneDigital Investment Advisors LLC 15,000 $61.7K <0.01% new 13F-HR Timeline BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 14,185 $58.3K <0.01% -550,803 13F-HR Timeline Group NEW YORK STATE COMMON RETIREMENT FUND More: the full row for NEW YORK STATE COMMON RETIREMENT FUND 14,154 $58.2K <0.01% 0 13F-HR Timeline Legato Capital Management LLC More: the full row for Legato Capital Management LLC 13,907 $57.2K 0.01% -1,223 13F-HR Timeline Tradition Wealth Management, LLC More: the full row for Tradition Wealth Management, LLC 12,700 $52.2K <0.01% +200 13F-HR Timeline NISA INVESTMENT ADVISORS, LLC More: the full row for NISA INVESTMENT ADVISORS, LLC 12,310 $50.6K <0.01% +5,487 13F-HR Timeline STATE BOARD OF ADMINISTRATION OF FLORID… More: the full row for STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 11,859 $48.7K <0.01% 0 13F-HR Timeline China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 11,503 $47.3K <0.01% +941 13F-HR Timeline Dynamic Technology Lab Private Ltd More: the full row for Dynamic Technology Lab Private Ltd 11,125 $45.7K 0.01% new 13F-HR Timeline ProShare Advisors LLC More: the full row for ProShare Advisors LLC 11,032 $45.3K <0.01% -1,297 13F-HR Timeline Accelerate Investment Advisors LLC More: the full row for Accelerate Investment Advisors LLC 10,670 $43.9K 0.03% new 13F-HR Timeline Tower Research Capital LLC (TRC) in group Tower Research Capital LLC (T… More: the full row for Tower Research Capital LLC (TRC) 10,216 $42K <0.01% +7,481 13F-HR Timeline Group LOS ANGELES CAPITAL MANAGEMENT LLC More: the full row for LOS ANGELES CAPITAL MANAGEMENT LLC 9,837 $40.4K <0.01% +9,521 13F-HR Timeline FMR LLC in group FMR LLC More: the full row for FMR LLC 8,881 $36.5K <0.01% +5,726 13F-HR Timeline Group SIMPLEX TRADING, LLC More: the full row for SIMPLEX TRADING, LLC 7,557 $31.1K <0.01% -17,127 13F-HR Timeline CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 6,406 $26.3K <0.01% -29,064 13F-HR Timeline Group Ameritas Investment Partners, Inc. in group Ameritas Investment Partners,… More: the full row for Ameritas Investment Partners, Inc. 5,415 $22.3K <0.01% 0 13F-HR Timeline Group Legal & General Group Plc in group Legal & General Group Plc More: the full row for Legal & General Group Plc 4,682 $19.2K <0.01% -772 13F-HR Timeline Group Caitong International Asset Management … More: the full row for Caitong International Asset Management Co., Ltd 4,404 $18.1K <0.01% +4,367 13F-HR Timeline State of Alaska, Department of Revenue More: the full row for State of Alaska, Department of Revenue 4,330 $17K <0.01% 0 13F-HR Timeline SUMMIT SECURITIES GROUP LLC More: the full row for SUMMIT SECURITIES GROUP LLC 3,429 $14.1K 0.01% +2,974 13F-HR Timeline MAI Capital Management More: the full row for MAI Capital Management 3,200 $13.2K <0.01% 0 13F-HR Timeline CALIFORNIA STATE TEACHERS RETIREMENT SY… More: the full row for CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 3,032 $12.5K <0.01% -164 13F-HR Timeline Quantbot Technologies LP More: the full row for Quantbot Technologies LP 2,677 $11K <0.01% new 13F-HR Timeline OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 1,906 $7.83K <0.01% -10,179 13F-HR Timeline Group PNC Financial Services Group, Inc. in group PNC Financial Services Group,… More: the full row for PNC Financial Services Group, Inc. 1,743 $7.16K <0.01% +1,331 13F-HR Timeline Group GAMMA Investing LLC More: the full row for GAMMA Investing LLC 1,656 $6.81K <0.01% -262 13F-HR Timeline GF FUND MANAGEMENT CO. LTD. More: the full row for GF FUND MANAGEMENT CO. LTD. 1,447 $5.95K <0.01% +174 13F-HR Timeline Parallel Advisors, LLC More: the full row for Parallel Advisors, LLC 1,272 $5.23K <0.01% -790 13F-HR/A Timeline Plante Moran Financial Advisors, LLC More: the full row for Plante Moran Financial Advisors, LLC 1,220 $5.01K <0.01% 0 13F-HR Timeline Aster Capital Management (DIFC) Ltd More: the full row for Aster Capital Management (DIFC) Ltd 402 $4.84K <0.01% new 13F-HR Timeline CWM, LLC in group CWM, LLC More: the full row for CWM, LLC 944 $3.88K <0.01% +832 13F-HR Timeline Group IAG Wealth Partners, LLC More: the full row for IAG Wealth Partners, LLC 927 $3.81K <0.01% 0 13F-HR Timeline SBI Securities Co., Ltd. More: the full row for SBI Securities Co., Ltd. 657 $2.7K <0.01% +395 13F-HR Timeline Rockefeller Capital Management L.P. in group Rockefeller Capital Managemen… More: the full row for Rockefeller Capital Management L.P. 616 $2.53K <0.01% +492 13F-HR Timeline Group Farther Finance Advisors, LLC More: the full row for Farther Finance Advisors, LLC 539 $2.32K <0.01% -2,709 13F-HR Timeline Olistico Wealth, LLC More: the full row for Olistico Wealth, LLC 400 $1.64K <0.01% 0 13F-HR Timeline Essential Partners LLC More: the full row for Essential Partners LLC 395 $1.62K <0.01% new 13F-HR Timeline JONES FINANCIAL COMPANIES LLLP in group JONES FINANCIAL COMPANIES LLLP More: the full row for JONES FINANCIAL COMPANIES LLLP 390 $1.56K <0.01% 0 13F-HR Timeline Group Private Wealth Management Group, LLC More: the full row for Private Wealth Management Group, LLC 364 $1.5K <0.01% new 13F-HR Timeline Sterling Capital Management LLC More: the full row for Sterling Capital Management LLC 363 $1.49K <0.01% -18 13F-HR Timeline Optiver Holding B.V. in group Optiver Holding B.V. More: the full row for Optiver Holding B.V. 357 $1.47K <0.01% +80 13F-HR/A Timeline Group HUNTINGTON NATIONAL BANK in group HUNTINGTON NATIONAL BANK More: the full row for HUNTINGTON NATIONAL BANK 301 $1.24K <0.01% 0 13F-HR Timeline Group ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 394 $1K <0.01% -2,996 13F-HR Timeline Group Allworth Financial LP More: the full row for Allworth Financial LP 219 $901 <0.01% -19 13F-HR Timeline ROTHSCHILD INVESTMENT LLC More: the full row for ROTHSCHILD INVESTMENT LLC 185 $760 <0.01% +165 13F-HR Timeline Parkside Financial Bank & Trust More: the full row for Parkside Financial Bank & Trust 145 $597 <0.01% new 13F-HR Timeline Bare Financial Services, Inc More: the full row for Bare Financial Services, Inc 116 $477 <0.01% new 13F-HR Timeline BOKF, NA in group BOKF, NA More: the full row for BOKF, NA 100 $411 <0.01% new 13F-HR Timeline Group NFSG Corp More: the full row for NFSG Corp 100 $411 <0.01% 0 13F-HR Timeline Smartleaf Asset Management LLC More: the full row for Smartleaf Asset Management LLC 96 $378 <0.01% -252 13F-HR Timeline GHP Investment Advisors, Inc. More: the full row for GHP Investment Advisors, Inc. 80 $329 <0.01% 0 13F-HR Timeline Larson Financial Group LLC More: the full row for Larson Financial Group LLC 78 $321 <0.01% -4,836 13F-HR Timeline Clearstead Advisors, LLC More: the full row for Clearstead Advisors, LLC 34 $141 <0.01% 0 13F-HR Timeline IFP Advisors, Inc More: the full row for IFP Advisors, Inc 27 $111 <0.01% -4,700 13F-HR Timeline CoreCap Advisors, LLC More: the full row for CoreCap Advisors, LLC 19 $78 <0.01% 0 13F-HR Timeline EverSource Wealth Advisors, LLC in group EverSource Wealth Advisors, L… More: the full row for EverSource Wealth Advisors, LLC 16 $66 <0.01% new 13F-HR/A Timeline Group Transamerica Financial Advisors, LLC in group Transamerica Financial Adviso… More: the full row for Transamerica Financial Advisors, LLC 11 $45 <0.01% new 13F-HR Timeline Group Hughes Financial Services, LLC More: the full row for Hughes Financial Services, LLC 1 $4 <0.01% new 13F-HR Timeline Covestor Ltd More: the full row for Covestor Ltd 20 $0 0% +14 13F-HR Timeline Value filed as zero, left out of ratios.