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Disclosery

CSTL CASTLE BIOSCIENCES INC

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COMMON STOCK (common), issuer CIK 1447362

192 managers (195 13F filers) reported a position in CSTL shares at 2025-12-31, 27,310,174 shares in all. 37 filers opened a position and 17 filers sold out during the quarter.

Managers
192
13F filers
195
New
37
Added
64
Reduced
69
Sold out
17
Shares held by filers
27,310,174

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

The latest Form 4 transactions, non-derivative.
OwnerDateSharesPriceFiling
MAETZOLD DEREK Jdirector, officer (Pres. & Chief Exec. Officer)2026-10-05-2,718 S$35.566Form 4
MAETZOLD DEREK Jdirector, officer (Pres. & Chief Exec. Officer)2026-10-05-3,198 S$35.566Form 4
MAETZOLD DEREK Jdirector, officer (Pres. & Chief Exec. Officer)2026-10-05-8,580 S$35.566Form 4
MAETZOLD DEREK Jdirector, officer (Pres. & Chief Exec. Officer)2026-10-05+8,165 M$2.39Form 4

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
BlackRock, Inc.in group BlackRock, Inc.3,105,246$121M<0.01%-84,65013F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC2,199,829$85.6M<0.01%+27,51113F-HRTimelineGroup
RTW INVESTMENTS, LP2,115,237$82.3M0.82%new13F-HRTimeline
PRINCIPAL FINANCIAL GROUP INCgroup of 2 filers holding1,807,644$70.3M+13,213Timeline
Portolan Capital Management, LLCin group Portolan Capital Management, …1,729,463$67.3M3.6%+214,35213F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP1,143,799$44.5M0.01%-330,29013F-HRTimelineGroup
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT…in group SUMMIT PARTNERS PUBLIC ASSET …1,058,725$41.2M1.16%+658,72513F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP736,454$28.6M<0.01%+12,37413F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC714,913$27.8M<0.01%+16,30313F-HRTimelineGroup
AIGH Capital Management LLC624,719$24.3M7.18%-82,56813F-HRTimeline
Allianz Asset Management GmbHin group Allianz SE622,299$24.2M0.03%-26,05213F-HRTimelineGroup
PALISADE CAPITAL MANAGEMENT, LP567,777$22.1M0.65%-70,87913F-HRTimeline
WASATCH ADVISORS LP537,241$20.9M0.12%-131,87913F-HRTimeline
Nuveen, LLCin group TIAA524,681$20.4M0.01%-432,40013F-HRTimelineGroup
SCHRODER INVESTMENT MANAGEMENT GROUP492,161$19.3M0.01%-2,78913F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC493,100$19.2M0.03%-69,50013F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC390,406$15.2M0.02%-61,24613F-HRTimelineGroup
Connor, Clark & Lunn Investment Managem…388,491$15.1M0.04%+52,60013F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC366,356$14.3M0.01%+115,44113F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC308,914$12M0.01%-266,17513F-HRTimelineGroup
EVENTIDE ASSET MANAGEMENT, LLC305,000$11.9M0.19%new13F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC287,235$11.2M<0.01%-57,86413F-HR/ATimelineGroup
KORNITZER CAPITAL MANAGEMENT INC /KS267,733$10.4M0.22%-10,58113F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/263,019$10.2M<0.01%-52,35113F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP262,243$10.2M<0.01%-20,02413F-HRTimelineGroup
Advisors Capital Management, LLC250,677$9.75M0.11%-3,52313F-HRTimeline
BRIDGEWAY CAPITAL MANAGEMENT, LLC246,920$9.61M0.2%+69,74013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co242,535$9.43M<0.01%+4,38113F-HRTimelineGroup
Qube Research & Technologies Ltd235,518$9.16M0.01%+14,55713F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND233,046$9.07M0.01%+3,00013F-HRTimeline
WELLINGTON MANAGEMENT GROUP LLPin group WELLINGTON MANAGEMENT GROUP L…218,560$8.5M<0.01%new13F-HRTimelineGroup
UBS Group AGgroup of 2 filers holding211,501$8.23M-137,321Timeline
SILVERCREST ASSET MANAGEMENT GROUP LLC205,002$7.97M0.05%-162,88613F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY203,577$7.92M<0.01%-66,05413F-HR/ATimelineGroup
BRAIDWELL LP177,183$6.89M0.22%-645,55213F-HRTimeline
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC168,646$6.56M0.01%+145,76213F-HRTimelineGroup
TUDOR INVESTMENT CORP ET AL167,178$6.5M0.04%+81,74313F-HRTimeline
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.159,709$6.21M<0.01%+67,09513F-HRTimelineGroup
Allspring Global Investments Holdings, …in group Allspring Global Investments …159,171$6.13M0.01%+2,65813F-HRTimelineGroup
Parkman Healthcare Partners LLC150,558$5.86M0.56%-325,01013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS150,011$5.84M<0.01%+10,09713F-HRTimelineGroup
Invesco Ltd.in group Invesco Ltd.135,461$5.27M<0.01%+79,62113F-HRTimelineGroup
Empowered Funds, LLC121,920$4.74M0.08%+23,74013F-HR/ATimeline
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.119,458$4.65M0.01%-217,50013F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding113,965$4.43M+78,365Timeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO90,032$3.5M<0.01%+62,25413F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp86,984$3.38M<0.01%-7,03213F-HRTimelineGroup
FRANKLIN RESOURCES INCin group Franklin Resources80,603$3.14M<0.01%-19,18413F-HRTimelineGroup
Birchview Capital, LP80,600$3.14M1.84%-30,00013F-HRTimeline
AMERICAN CENTURY COMPANIES INCin group AMERICAN CENTURY COMPANIES INC77,768$3.03M<0.01%-4,74413F-HRTimelineGroup
Orion Porfolio Solutions, LLC74,653$2.9M0.02%-1,69113F-HRTimeline
Informed Momentum Co LLC74,138$2.88M0.32%new13F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC72,149$2.81M<0.01%-91913F-HRTimelineGroup
Trexquant Investment LP64,605$2.51M0.02%-113,83713F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC63,881$2.48M<0.01%+13,03913F-HRTimelineGroup
ENVESTNET ASSET MANAGEMENT INCin group ENVESTNET ASSET MANAGEMENT INC61,966$2.41M<0.01%-4,96213F-HRTimelineGroup
Swiss National Bank57,300$2.23M<0.01%+1,30013F-HRTimeline
Squarepoint Ops LLCin group Squarepoint Ops LLC55,118$2.14M<0.01%new13F-HRTimelineGroup
HRT FINANCIAL LP47,654$1.85M0.01%+41513F-HRTimeline
PANAGORA ASSET MANAGEMENT INC45,995$1.79M0.01%+24,59713F-HRTimeline
FMR LLCin group FMR LLC42,286$1.64M<0.01%+13,74413F-HRTimelineGroup
SEI INVESTMENTS COin group SEI INVESTMENTS CO39,727$1.55M<0.01%+12,95613F-HRTimelineGroup
RHUMBLINE ADVISERS38,468$1.5M<0.01%-5,29013F-HRTimeline
MACKENZIE FINANCIAL CORP37,317$1.46M<0.01%+13,11313F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.36,404$1.42M<0.01%+35,99613F-HRTimelineGroup
AMERIPRISE FINANCIAL INCin group AMERIPRISE FINANCIAL INC35,368$1.38M<0.01%-220,86513F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN34,212$1.33M<0.01%+10,23313F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/34,138$1.33M<0.01%+1,54513F-HRTimeline
CITIGROUP INCin group CITIGROUP INC32,422$1.26M<0.01%+28,17213F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc29,735$1.16M<0.01%-5,17313F-HRTimelineGroup
Universal- Beteiligungs- und Serviceges…in group Universal- Beteiligungs- und …29,357$1.14M<0.01%-52613F-HRTimelineGroup
PERKINS CAPITAL MANAGEMENT INC28,045$1.09M0.87%-10013F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…27,725$1.08M<0.01%+3,10313F-HRTimeline
ALLIANCEBERNSTEIN L.P.25,270$983K<0.01%-8,10013F-HRTimeline
TRUIST FINANCIAL CORPin group TRUIST FINANCIAL CORP23,628$919K<0.01%+25713F-HRTimelineGroup
Engineers Gate Manager LP22,949$893K0.01%-23,55713F-HRTimeline
CAXTON ASSOCIATES LLP22,464$874K0.02%new13F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\22,384$871K<0.01%+5,74213F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd22,125$861K0.02%new13F-HRTimelineGroup
FOX RUN MANAGEMENT, L.L.C.21,884$851K0.13%+8,06413F-HRTimeline
Schonfeld Strategic Advisors LLC21,476$835K<0.01%-66,21513F-HRTimeline
SG Americas Securities, LLC21,262$827K<0.01%+8,20113F-HRTimeline
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC19,486$760K<0.01%-13,74713F-HR/ATimelineGroup
ALGERT GLOBAL LLC18,978$738K0.01%-38,91713F-HR/ATimeline
SummitTX Capital, L.P.17,410$677K0.02%-27,59013F-HRTimeline
AlphaQuest LLC17,116$666K0.04%+2,57213F-HRTimeline
Verition Fund Management LLC16,811$654K<0.01%+1,16913F-HRTimeline
First Bank & Trust16,706$650K0.11%-3,09313F-HRTimeline
Creative Planningin group Creative Planning16,141$628K<0.01%-13513F-HRTimelineGroup
MetLife Investment Management, LLCin group MetLife Investment Management…15,881$618K<0.01%013F-HRTimelineGroup
JANUS HENDERSON GROUP PLCin group Janus Henderson15,037$585K<0.01%+5,90013F-HRTimelineGroup
LOS ANGELES CAPITAL MANAGEMENT LLC23,631$572K<0.01%-49013F-HRTimeline
Mirae Asset Global Investments Co., Ltd.group of 2 filers holding14,641$570K+247Timeline
Parallel Advisors, LLC13,986$544K0.01%-3,80013F-HRTimeline
Oak Harvest Investment Services13,485$525K0.06%-3,39813F-HRTimeline
HARBOR CAPITAL ADVISORS, INC.13,432$523K0.04%+26113F-HRTimeline
Y-Intercept (Hong Kong) Ltd13,246$515K0.01%new13F-HRTimeline
Counterpoint Mutual Funds LLC12,952$504K0.04%new13F-HRTimeline
STRS OHIO12,600$490K<0.01%+2,80013F-HRTimeline
Summit Global Investmentsin group Summit Global Investments12,365$481K0.03%+1313F-HRTimelineGroup
Inspire Investing, LLCin group Inspire Investing, LLC12,011$467K0.04%-7,87613F-HRTimelineGroup
Zurcher Kantonalbank (Zurich Cantonalba…11,810$459K<0.01%-39713F-HRTimeline
DIVERSIFY WEALTH MANAGEMENT, LLCin group Diversify Advisory Services, …11,588$459K0.02%-15913F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC11,718$456K<0.01%-67413F-HRTimeline
Man Group plcin group Man Group plc11,585$451K<0.01%new13F-HRTimelineGroup
Jackson Creek Investment Advisors LLC11,235$437K0.13%new13F-HRTimeline
STEPHENS INC /AR/in group Stephens Investment Managemen…11,122$433K0.01%013F-HRTimelineGroup
Graham Capital Management, L.P.10,928$425K0.01%-10,20513F-HRTimeline
LPL Financial LLC10,877$423K<0.01%+1,48013F-HRTimeline
TritonPoint Partners, LLCgroup of 2 filers holding10,777$419K-30,000Timeline
Aquatic Capital Management LLC10,570$411K0.01%+8,23513F-HRTimeline
Green Alpha Advisors, LLC10,236$398K0.36%+69813F-HRTimeline
Quantinno Capital Management LP9,332$363K<0.01%new13F-HRTimeline
Cetera Investment Advisers8,935$348K<0.01%new13F-HRTimeline
SIMON QUICK ADVISORS, LLC8,561$333K0.01%-5,00113F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …8,487$330K<0.01%-1,05213F-HRTimelineGroup
GLENMEDE TRUST CO NAin group GLENMEDE TRUST CO NA8,190$319K<0.01%13F-HRTimelineGroup
ARIZONA STATE RETIREMENT SYSTEM8,071$314K<0.01%new13F-HRTimeline
Police & Firemen's Retirement System of…7,829$305K<0.01%013F-HRTimeline
INTRUST BANK NA7,378$287K0.02%new13F-HRTimeline
STATE BOARD OF ADMINISTRATION OF FLORID…7,154$278K<0.01%new13F-HRTimeline
Verdad Advisers, LP7,085$276K0.32%13F-HRTimeline
ARROWSTREET CAPITAL, LIMITED PARTNERSHIPin group ARROWSTREET CAPITAL, LIMITED …7,029$273K<0.01%new13F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC6,591$256K<0.01%new13F-HRTimeline
ProShare Advisors LLC6,478$252K<0.01%new13F-HRTimeline
Blueshift Asset Management, LLC6,458$251K0.07%new13F-HRTimeline
Capstone Capital Management Ltd6,446$251K0.24%13F-HRTimeline
CANADA PENSION PLAN INVESTMENT BOARD6,300$245K<0.01%+3,90013F-HRTimeline
KLP KAPITALFORVALTNING AS6,200$241K<0.01%-2,70013F-HRTimeline
Cornerstone Investment Partners, LLC6,078$236K0.01%new13F-HRTimeline
Portside Wealth Group, LLC5,942$231K0.03%new13F-HRTimeline
Pictet Asset Management Holding SAin group Pictet Asset Management Holdi…5,899$229K<0.01%new13F-HRTimelineGroup
Lido Advisors, LLCin group Lido Advisors, LLC10,036$229K<0.01%013F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC5,500$214K<0.01%new13F-HRTimelineGroup
ASSETMARK, INCin group ASSETMARK, INC5,287$206K<0.01%-41813F-HRTimelineGroup
VOYA INVESTMENT MANAGEMENT LLCin group VOYA INVESTMENT MANAGEMENT LLC5,246$204K<0.01%new13F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC5,238$204K<0.01%new13F-HRTimelineGroup
China Universal Asset Management Co., L…4,756$185K0.01%-32913F-HRTimeline
GLOBEFLEX CAPITAL L P3,759$146K0.02%new13F-HRTimeline
Farther Finance Advisors, LLC3,337$130K<0.01%+1,94513F-HRTimeline
CANADA LIFE ASSURANCE Coin group CANADA LIFE ASSURANCE Co3,244$126K<0.01%-7,46913F-HRTimelineGroup
HARBOUR INVESTMENTS, INC.3,137$122K<0.01%013F-HRTimeline
State of Wyoming3,014$117K0.01%new13F-HRTimeline
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…2,488$96.8K<0.01%-2013F-HRTimelineGroup
Persistent Asset Partners Ltd2,463$95.8K0.05%new13F-HRTimeline
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…2,373$92.3K<0.01%013F-HRTimelineGroup
CWM, LLCin group CWM, LLC2,302$90K<0.01%+39113F-HRTimelineGroup
Caitong International Asset Management …2,099$81.7K0.02%+1,37113F-HR/ATimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…2,013$78.3K<0.01%-1,65313F-HRTimelineGroup
BNP PARIBAS ASSET MANAGEMENT Holding S.…in group BNP PARIBAS ASSET MANAGEMENT …1,839$72K<0.01%+1,37813F-HRTimelineGroup
Sterling Capital Management LLC1,637$63.7K<0.01%-32313F-HRTimeline
State of Alaska, Department of Revenue1,553$60K<0.01%013F-HRTimeline
Global Retirement Partners, LLC1,100$42.8K<0.01%013F-HRTimeline
Covestor Ltd998$39K0.02%-1,07113F-HRTimeline
AMALGAMATED BANK892$35K<0.01%-113F-HRTimeline
Kemnay Advisory Services Inc.889$34.6K0.01%new13F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA865$33K<0.01%-3213F-HRTimelineGroup
FIRST HORIZON CORP678$26.4K<0.01%+23113F-HRTimeline
FEDERATED HERMES, INC.in group FEDERATED HERMES, INC.660$25.7K<0.01%new13F-HRTimelineGroup
GF FUND MANAGEMENT CO. LTD.573$22.3K<0.01%-5113F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…546$21.2K<0.01%+43113F-HRTimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP515$20K<0.01%+49013F-HRTimelineGroup
Hughes Financial Services, LLC436$17K<0.01%+113F-HRTimeline
Rossby Financial, LCC429$16.7K0.01%+4713F-HRTimeline
QUADRANT CAPITAL GROUP LLC336$13.1K<0.01%013F-HRTimeline
NISA INVESTMENT ADVISORS, LLC281$10.9K<0.01%-8313F-HRTimeline
Versant Capital Management, Inc181$7.04K<0.01%013F-HRTimeline
Aster Capital Management (DIFC) Ltd151$5.87K<0.01%new13F-HRTimeline
HUNTINGTON NATIONAL BANKin group HUNTINGTON NATIONAL BANK139$5.41K<0.01%013F-HRTimelineGroup
Essential Partners LLC134$5.21K<0.01%+1113F-HRTimeline
BFSG, LLC90$3.5K<0.01%013F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…87$3.38K<0.01%new13F-HR/ATimelineGroup
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.86$3K<0.01%013F-HRTimelineGroup
ROTHSCHILD INVESTMENT LLC53$2.06K<0.01%-213F-HRTimeline
IFP Advisors, Inc52$2.02K<0.01%013F-HRTimeline
SBI Securities Co., Ltd.52$2.02K<0.01%-113F-HRTimeline
GAMMA Investing LLC52$2.02K<0.01%013F-HRTimeline
Spire Wealth Managementin group Spire Wealth Management50$1.95K<0.01%013F-HRTimelineGroup
US BANCORP \DE\in group US BANCORP \DE\48$1.87K<0.01%+2213F-HRTimelineGroup
Quantbot Technologies LP47$1.83K<0.01%new13F-HRTimeline
SIGNATUREFD, LLC45$1.75K<0.01%013F-HRTimeline
Arax Advisory Partners37$1.44K<0.01%-53713F-HRTimeline
Allworth Financial LP30$1.17K<0.01%+1113F-HRTimeline
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…28$1.09K<0.01%new13F-HR/ATimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…28$1.09K<0.01%+813F-HRTimelineGroup
Parkside Financial Bank & Trust25$973<0.01%new13F-HRTimeline
Torren Management, LLC21$817<0.01%13F-HRTimeline
Missouri Trust & Investment Co19$739<0.01%013F-HRTimeline
Signature Equity Partners, LLC16$622<0.01%13F-HRTimeline
True Wealth Design, LLC5$195<0.01%+413F-HRTimeline
Sunbelt Securities, Inc.1$39<0.01%new13F-HRTimeline
Larson Financial Group LLC1$39<0.01%013F-HRTimeline

Events

  • MAETZOLD DEREK J disposed of 6,331 CSTL shares on 2026-10-05, Form 4 filed 2026-10-07. 0001628280-26-065327

    Accepted , ingested