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Omega Fund Management, LLC

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13F filer, CIK 1637359, Boston, MA

Omega Fund Management, LLC reported $163,149,229 across 10 holdings for the quarter ended 2026-03-31, in a 13F-HR filed 2026-05-15.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001193125-26-225480

Period
2026-03-31
Reported value
$163M
Holdings
10
Top 10 weight
100%
New
0
Sold out
1

Largest buys vs the previous quarter

SecurityShares changeApprox. value
BCAXadded+187,500$3.73M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
UPBexited-1,326,293-$36M
ALMSreduced-411,968-$9.08M
KMTSreduced-351,442-$7M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q1 2026

Share positions as resolved from 13F-HR 0001193125-26-225480, largest first. % of portfolio is the value over $163,149,231, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
BCAXBICARA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 2,204,650 shares; 2024Q4: 2,204,650 shares; 2025Q1: 2,204,650 shares; 2025Q2: 2,204,650 shares; 2025Q3: 2,204,650 shares; 2025Q4: 2,204,650 shares; 2026Q1: 2,392,150 shares 2,392,150$47.6M29.16%+187,500Timeline
NUVBNUVATION BIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 13,072,340 shares; 2024Q4: 13,072,340 shares; 2025Q1: 13,072,340 shares; 2025Q2: 11,042,728 shares; 2025Q3: 8,831,089 shares; 2025Q4: 8,081,089 shares; 2026Q1: 8,081,089 shares 8,081,089$34.7M21.25%0Timeline
BBOTBRIDGEBIO ONCOLOGY THERAPEUTQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 3,289,661 shares; 2025Q4: 3,289,661 shares; 2026Q1: 3,289,661 shares 3,289,661$29.4M18.05%0Timeline
KMTSKESTRA MED TECHNOLOGIES LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 1,795,893 shares; 2025Q2: 1,645,893 shares; 2025Q3: 1,645,893 shares; 2025Q4: 1,373,591 shares; 2026Q1: 1,022,149 shares 1,022,149$20.4M12.49%-351,442Timeline
BBNXBETA BIONICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 1,988,287 shares; 2025Q2: 1,988,287 shares; 2025Q3: 1,920,125 shares; 2025Q4: 1,316,183 shares; 2026Q1: 1,316,183 shares 1,316,183$13.2M8.08%0Timeline
ENGNENGENE HOLDINGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 1,076,357 shares; 2024Q4: 526,357 shares; 2025Q1: 526,357 shares; 2025Q2: 526,357 shares; 2025Q3: 526,357 shares; 2025Q4: 876,357 shares; 2026Q1: 876,357 shares 876,357$5.97M3.66%0Timeline
ALMSALUMIS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 653,223 shares; 2024Q4: 653,223 shares; 2025Q1: 653,223 shares; 2025Q2: 653,223 shares; 2025Q3: 653,223 shares; 2025Q4: 653,223 shares; 2026Q1: 241,255 shares 241,255$5.31M3.26%-411,968Timeline
SANASANA BIOTECHNOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 843,750 shares; 2024Q4: 843,750 shares; 2025Q1: 843,750 shares; 2025Q2: 843,750 shares; 2025Q3: 843,750 shares; 2025Q4: 843,750 shares; 2026Q1: 843,750 shares 843,750$2.43M1.49%0Timeline
IMAIMAGENEBIO INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 455,361 shares; 2025Q4: 455,361 shares; 2026Q1: 455,361 shares 455,361$2.28M1.4%0Timeline
REPLREPLIMUNE GROUP INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q2: restricted; 2024Q3: 2,461,319 shares; 2024Q4: 1,975,203 shares; 2025Q1: 1,975,203 shares; 2025Q2: 1,975,203 shares; 2025Q3: 248,672 shares; 2025Q4: 248,672 shares; 2026Q1: 248,672 shares 248,672$1.91M1.17%0Timeline

Sold out in Q1 2026

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
UPBUPSTREAM BIO INC1,326,293$36Mshares

How Q1 2026 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001193125-26-225480 base2026-05-15acceptance time not in the bulk data set