ADAGE CAPITAL PARTNERS GP, L.L.C.
Follow13F filer, CIK 1165408, Boston, MA
ADAGE CAPITAL PARTNERS GP, L.L.C. reported $66,075,303,576 across 905 holdings for the quarter ended 2025-12-31, in a 13F-HR filed 2026-02-17. Its ten largest share positions make up 31.48% of the portfolio.
Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001172661-26-000912
- Period
- 2025-12-31
- Reported value
- $66.1B
- Holdings
- 905
- Top 10 weight
- 31.48%
- New
- 183
- Sold out
- 150
Part of the filer group ADAGE CAPITAL PARTNERS GP, L.L.C.
How groups are builtLargest buys vs the previous quarter
| Security | Shares change | Approx. value |
|---|---|---|
| NFLXadded | +3,665,697 | $344M |
| MRKadded | +1,634,216 | $172M |
| BAadded | +729,708 | $158M |
| Dnew | +2,141,911 | $125M |
| RVMDadded | +1,463,155 | $117M |
Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.
Largest sells vs the previous quarter
| Security | Shares change | Approx. value |
|---|---|---|
| PRAXreduced | -1,408,772 | -$415M |
| CVXreduced | -1,504,675 | -$229M |
| INSMreduced | -952,503 | -$166M |
| PGreduced | -962,853 | -$138M |
| 89BIO INCexited | -9,097,587 | -$134M |
Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.
Back to all 902 share positions
Options
Puts and calls, as filed. The amount and value describe the underlying shares, not the option premium, so they stay out of % of portfolio (H5).
| Security | Type | Amount | Value | Change |
|---|---|---|---|---|
| CNCCENTENE CORP DEL Stock | call | 250,000 | $10.3M | new |
Principal amounts
Notes and convertibles filed as a face amount (PRN). A face amount is never added to a share count (H6).
| Security | Type | Amount | Value | Change |
|---|---|---|---|---|
| KOSMOS ENERGY LTDKOSMOS ENERGY LTD NOTE 3.125% 3/1 | principal | 38,392,000 | $16M | +20,892,000 |
| T1 ENERGY INCT1 ENERGY INC NOTE 5.250%12/0 | principal | 10,000,000 | $12.8M | new |
Sold out in Q4 2025
Positions in the previous quarter's report that this quarter's report no longer lists.
| Security | Shares before | Value before | Type |
|---|---|---|---|
| 89BIO INC89BIO INC | 9,097,587 | $134M | shares |
| SLNOSOLENO THERAPEUTICS INC | 1,401,576 | $94.7M | shares |
| DUKDUKE ENERGY CORP NEW | 707,113 | $87.5M | shares |
| KKELLANOVA | 1,053,460 | $86.4M | shares |
| SRRKSCHOLAR ROCK HLDG CORP | 1,951,866 | $72.7M | shares |
| MERUS N VMERUS N V | 600,000 | $56.5M | shares |
| SPRSPIRIT AEROSYSTEMS HLDGS INC | 1,440,641 | $55.6M | shares |
| SNDXSYNDAX PHARMACEUTICALS INC | 3,311,963 | $51M | shares |
| RGAREINSURANCE GROUP AMER INC | 250,000 | $48M | shares |
| CNXCNX RES CORP | 1,400,000 | $45M | shares |
| RSGREPUBLIC SVCS INC | 183,968 | $42.2M | shares |
| KFYKORN FERRY | 575,000 | $40.2M | shares |
| TTMITTM TECHNOLOGIES INC | 654,174 | $37.7M | shares |
| EHCENCOMPASS HEALTH CORP | 284,169 | $36.1M | shares |
| HNIHNI CORP | 720,000 | $33.7M | shares |
| WECWEC ENERGY GROUP INC | 293,008 | $33.6M | shares |
| MRSHMARSH & MCLENNAN COS INC | 165,061 | $33.3M | shares |
| LGNLEGENCE CORP | 1,047,148 | $32.3M | shares |
| AGIOAGIOS PHARMACEUTICALS INC | 800,000 | $32.1M | shares |
| BCSSUBAIN CAP GSS INVT CORP | 3,000,000 | $30.3M | shares |
| IRONDISC MEDICINE INC | 450,000 | $29.7M | shares |
| LENZLENZ THERAPEUTICS INC | 627,618 | $29.2M | shares |
| SOSOUTHERN CO | 300,300 | $28.5M | shares |
| DOCUDOCUSIGN INC | 365,000 | $26.3M | shares |
| AEEAMEREN CORP | 246,190 | $25.7M | shares |
| LLYVKLIBERTY MEDIA CORP DEL | 253,816 | $24.6M | shares |
| VOYAVOYA FINANCIAL INC | 325,000 | $24.3M | shares |
| BTSGBRIGHTSPRING HEALTH SVCS INC | 820,518 | $24.3M | shares |
| PRIMPRIMORIS SVCS CORP | 175,000 | $24M | shares |
| INTERPUBLIC GROUP COSINTERPUBLIC GROUP COS | 855,288 | $23.9M | shares |
| FNVFRANCO NEV CORP | 100,000 | $22.3M | shares |
| FITBFIFTH THIRD BANCORP | 497,597 | $22.2M | shares |
| MASIMASIMO CORP | 150,000 | $22.1M | shares |
| CNMCORE & MAIN INC | 404,000 | $21.7M | shares |
| SOLVSOLVENTUM CORP | 292,622 | $21.4M | shares |
| VCVISTEON CORP | 175,000 | $21M | shares |
| MASMASCO CORP | 293,100 | $20.6M | shares |
| TLNCUTALON CAP CORP | 2,025,000 | $20.3M | shares |
| CMSCMS ENERGY CORP | 272,461 | $20M | shares |
| MHKMOHAWK INDS INC | 147,470 | $19M | shares |
| HVMCUHIGHVIEW MERGER CORP | 1,800,000 | $18.2M | shares |
| OTGAUOTG ACQUISITION CORP. I | 1,800,000 | $18.1M | shares |
| MLMMARTIN MARIETTA MATLS INC | 27,987 | $17.6M | shares |
| WBIWATERBRIDGE INFRASTRUCTURE L | 669,663 | $16.9M | shares |
| AEMAGNICO EAGLE MINES LTD | 100,000 | $16.9M | shares |
| PLYMPLYMOUTH INDUSTRIAL REIT INC | 734,500 | $16.4M | shares |
| PLGOPELAGOS INS CAP LTD | 900,000 | $16.3M | shares |
| ABEOABEONA THERAPEUTICS INC | 3,047,985 | $16.1M | shares |
| VALEVALE S A | 1,400,000 | $15.2M | shares |
| ACVAACV AUCTIONS INC | 1,500,000 | $14.9M | shares |
| LXPLXP INDUSTRIAL TRUST | 1,650,000 | $14.8M | shares |
| MGAMAGNA INTL INC | 311,576 | $14.8M | shares |
| ALEALLETE INC | 211,555 | $14M | shares |
| IVERSIFIED ENERGY COMPANY PIVERSIFIED ENERGY COMPANY P | 1,000,000 | $14M | shares |
| LATAUGALATA ACQUISITION CORP II | 1,350,000 | $13.5M | shares |
| ACHCACADIA HEALTHCARE COMPANY IN | 538,087 | $13.3M | shares |
| SPLVINVESCO EXCH TRADED FD TR II | 180,000 | $13.2M | shares |
| RNSTRENASANT CORP | 334,836 | $12.4M | shares |
| MTBM & T BK CORP | 62,307 | $12.3M | shares |
| BLZRUTRAILBLAZER ACQUISITION CORP | 1,200,000 | $12.3M | shares |
| SLGNSILGAN HLDGS INC | 284,526 | $12.2M | shares |
| ESSESSEX PPTY TR INC | 43,600 | $11.7M | shares |
| MCHPMICROCHIP TECHNOLOGY INC. | 181,300 | $11.6M | shares |
| RMDRESMED INC | 42,531 | $11.6M | shares |
| ROLROLLINS INC | 189,342 | $11.1M | shares |
| MLTXMOONLAKE IMMUNOTHERAPEUTICS | 1,500,000 | $10.8M | shares |
| PCRXPACIRA BIOSCIENCES INC | 409,997 | $10.6M | shares |
| SWKSSKYWORKS SOLUTIONS INC | 135,150 | $10.4M | shares |
| MBVIUM3-BRIGADE ACQUISITION VI CO | 1,000,000 | $10.1M | shares |
| BDCIUBTC DEV CORP | 1,000,000 | $10.1M | shares |
| RVTYREVVITY INC | 105,688 | $9.26M | shares |
| SCISERVICE CORP INTL | 110,603 | $9.2M | shares |
| VVVVALVOLINE INC | 250,000 | $8.98M | shares |
| CPRICAPRI HOLDINGS LIMITED | 447,693 | $8.92M | shares |
| ZTSZOETIS INC | 60,097 | $8.79M | shares |
| OSKOSHKOSH CORP | 67,000 | $8.69M | shares |
| CBSHCOMMERCE BANCSHARES INC | 143,215 | $8.56M | shares |
| TLNTALEN ENERGY CORP | 20,000 | $8.51M | shares |
| WCNWASTE CONNECTIONS INC | 46,696 | $8.21M | shares |
| KNTKKINETIK HOLDINGS INC | 187,500 | $8.01M | shares |
| AAOIAPPLIED OPTOELECTRONICS INC | 300,000 | $7.78M | shares |
| CNCCENTENE CORP DEL | 216,712 | $7.73M | shares |
| LKQLKQ CORP | 234,200 | $7.15M | shares |
| DOCNDIGITALOCEAN HLDGS INC | 200,000 | $6.83M | shares |
| ENGNENGENE HOLDINGS INC | 1,000,000 | $6.83M | shares |
| EMNEASTMAN CHEM CO | 104,543 | $6.59M | shares |
| TET1 ENERGY INC | 3,000,000 | $6.54M | shares |
| SLVISHARES SILVER TR | 150,000 | $6.36M | shares |
| KGCKINROSS GOLD CORP | 250,000 | $6.21M | shares |
| LRMRLARIMAR THERAPEUTICS INC | 1,900,000 | $6.14M | shares |
| SYBTSTOCK YDS BANCORP INC | 87,500 | $6.12M | shares |
| BDXBECTON DICKINSON & CO | 32,695 | $6.12M | shares |
| XRAYDENTSPLY SIRONA INC | 397,775 | $5.05M | shares |
| FLYFIREFLY AEROSPACE INC | 169,879 | $4.98M | shares |
| HTOH2O AMERICA | 100,000 | $4.87M | shares |
| HAYWHAYWARD HLDGS INC | 311,379 | $4.71M | shares |
| AARDAARDVARK THERAPEUTICS INC | 350,000 | $4.65M | shares |
| EVREVERCORE INC | 13,000 | $4.39M | shares |
| VISTVISTA ENERGY S.A.B. DE C.V. | 125,000 | $4.3M | shares |
| PRMEPRIME MEDICINE INC | 771,361 | $4.27M | shares |
| BEAMBEAM THERAPEUTICS INC | 175,000 | $4.25M | shares |
| CTRICENTURI HOLDINGS INC | 200,000 | $4.23M | shares |
| CDRECADRE HLDGS INC | 115,326 | $4.21M | shares |
| ASPEN INSURANCE HOLDINGS-AASPEN INSURANCE HOLDINGS-A | 112,500 | $4.13M | shares |
| ATRAPTARGROUP INC | 29,948 | $4M | shares |
| MLYSMINERALYS THERAPEUTICS INC | 105,000 | $3.98M | shares |
| ALAIR LEASE CORP | 61,990 | $3.95M | shares |
| SFNCSIMMONS FIRST NATL CORP | 199,734 | $3.83M | shares |
| VTRSVIATRIS INC | 367,136 | $3.63M | shares |
| AOSSMITH A O CORP | 48,992 | $3.6M | shares |
| BNLBROADSTONE NET LEASE INC | 200,000 | $3.57M | shares |
| PNTGPENNANT GROUP INC | 139,613 | $3.52M | shares |
| DBVTDBV TECHNOLOGIES S A | 345,934 | $3.46M | shares |
| CRGYCRESCENT ENERGY COMPANY | 380,564 | $3.39M | shares |
| IEIVANHOE ELECTRIC INC | 258,323 | $3.24M | shares |
| COMPCOMPASS INC | 400,000 | $3.21M | shares |
| LBRXLB PHARMACEUTICALS INC | 200,000 | $3.16M | shares |
| DNTHDIANTHUS THERAPEUTICS INC | 77,000 | $3.03M | shares |
| ASICATEGRITY SPECIALTY IN CO HO | 150,000 | $2.97M | shares |
| Surmodics IncSurmodics Inc | 91,270 | $2.73M | shares |
| USPHU S PHYSICAL THERAPY | 32,000 | $2.72M | shares |
| LYBLYONDELLBASELL INDUSTRIES NV | 54,300 | $2.66M | shares |
| HOUSANYWHERE REAL ESTATE INC | 247,679 | $2.62M | shares |
| PSAPUBLIC STORAGE | 8,792 | $2.54M | shares |
| CBIOCRESCENT BIOPHARMA INC. | 200,005 | $2.38M | shares |
| KNSAKINIKSA PHARMACEUTICALS INTL | 59,000 | $2.29M | shares |
| CYTKCYTOKINETICS INC | 38,000 | $2.09M | shares |
| RCUSARCUS BIOSCIENCES INC | 152,000 | $2.07M | shares |
| REXRREXFORD INDL RLTY INC | 50,000 | $2.06M | shares |
| NEXTNEXTDECADE CORP | 300,000 | $2.04M | shares |
| VSTSVESTIS CORPORATION | 444,844 | $2.02M | shares |
| GOSSGOSSAMER BIO INC | 726,800 | $1.91M | shares |
| AAPADVANCE AUTO PARTS INC | 28,380 | $1.74M | shares |
| SUTRO BIOPHARMA INCSUTRO BIOPHARMA INC | 2,000,000 | $1.74M | shares |
| ANGOANGIODYNAMICS INC | 150,000 | $1.68M | shares |
| ELVNENLIVEN THERAPEUTICS INC | 73,000 | $1.49M | shares |
| SAICSCIENCE APPLICATIONS INTL CO | 15,000 | $1.49M | shares |
| OCOWENS CORNING NEW | 10,000 | $1.41M | shares |
| ALGSALIGOS THERAPEUTICS INC | 140,000 | $1.37M | shares |
| PCHPOTLATCHDELTIC CORP | 30,000 | $1.22M | shares |
| SITESITEONE LANDSCAPE SUPPLY INC | 8,773 | $1.13M | shares |
| CHECHEMED CORP NEW | 2,500 | $1.12M | shares |
| RALRALLIANT CORP | 19,151 | $837K | shares |
| RGENREPLIGEN CORP | 5,000 | $668K | shares |
| EPSNEPSILON ENERGY LTD | 101,835 | $513K | shares |
| IFRXINFLARX NV | 331,113 | $444K | shares |
| VERUVERU INC | 100,000 | $380K | shares |
| NUAINEW ERA ENERGY & DIGITAL INC | 200,000 | $368K | shares |
| PTENPATTERSON-UTI ENERGY INC | 60,000 | $311K | shares |
| DYNCWDYNAMIX CORP | 125,000 | $264K | shares |
How Q4 2025 was built
Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).
| Filing | Role | Amendment | Filed | Accepted | Ingested |
|---|---|---|---|---|---|
| 13F-HR 0001172661-26-000912 | base | 2026-02-17 | acceptance time not in the bulk data set |