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Disclosery

PTGX PROTAGONIST THERAPEUTICS INC

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COM (common), issuer CIK 1377121

311 managers (317 13F filers) reported a position in PTGX shares at 2025-12-31, 71,028,771 shares in all. 65 filers opened a position and 39 filers sold out during the quarter.

Managers
311
13F filers
317
New
65
Added
97
Reduced
103
Sold out
39
Shares held by filers
71,028,771

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
XPONANCE LLC4,588$401K<0.01%+5413F-HRTimeline
Ensign Peak Advisors, Inc4,486$392K<0.01%-6,50013F-HR/ATimeline
Orion Porfolio Solutions, LLC4,396$384K<0.01%-2,53213F-HRTimeline
US BANCORP \DE\in group US BANCORP \DE\4,395$384K<0.01%-1,45713F-HRTimelineGroup
O'SHAUGHNESSY ASSET MANAGEMENT, LLC4,369$382K<0.01%new13F-HRTimeline
Brooklyn Investment Group4,331$381K0.02%new13F-HRTimeline
LOS ANGELES CAPITAL MANAGEMENT LLC4,727$368K<0.01%new13F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.4,201$367K<0.01%+2,81013F-HRTimelineGroup
Vident Advisory, LLCin group Vident Advisory, LLC4,191$366K<0.01%-87913F-HRTimelineGroup
New Vernon Capital Holdings II LLCin group New Vernon Capital Holdings I…4,137$361K0.17%-3,06113F-HRTimelineGroup
King Wealth Management Group4,000$349K0.04%-2,00013F-HRTimeline
Allspring Global Investments Holdings, …in group Allspring Global Investments …3,985$347K<0.01%new13F-HRTimelineGroup
Crossmark Global Holdings, Inc.3,960$346K<0.01%-613F-HRTimeline
CIBC Bancorp USA Inc.group of 2 filers holding3,864$337KnewTimeline
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/3,808$332K<0.01%-5613F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC3,780$330K<0.01%-20513F-HRTimeline
Vestcor Inc3,765$329K0.01%-1,25713F-HRTimeline
Abacus Wealth Partners, LLC3,763$329K0.03%new13F-HRTimeline
M&T Bank Corpin group M&T Bank Corp3,753$328K<0.01%new13F-HR/ATimelineGroup
Velan Capital Investment Management LP3,700$323K0.19%013F-HRTimeline
BURNEY CO/3,680$321K0.01%-1,38413F-HRTimeline
MACKENZIE FINANCIAL CORP3,648$318K<0.01%-41613F-HRTimeline
WEALTH ENHANCEMENT ADVISORY SERVICES, L…3,554$292K<0.01%+4313F-HRTimeline
Rockefeller Capital Management L.P.in group Rockefeller Capital Managemen…3,292$288K<0.01%+31213F-HR/ATimelineGroup
LPL Financial LLC3,265$285K<0.01%-1,72913F-HRTimeline
CERTUITY, LLC3,251$284K0.02%-1,28413F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA3,183$278K<0.01%-66,81313F-HRTimelineGroup
AlphaGrep UK Ltd3,070$268K0.09%13F-HRTimeline
Vise Technologies, Inc.2,996$262K0.01%new13F-HRTimeline
LANARK FINANCIAL, INC.2,977$260K0.02%+1913F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…2,959$258K<0.01%+22113F-HRTimelineGroup
Pinnacle Wealth Planning Services, Inc.2,864$250K0.03%new13F-HRTimeline
EVERGREEN CAPITAL MANAGEMENT LLC2,812$246K0.01%new13F-HRTimeline
Virtus Investment Advisers, LLCin group Virtus Investment Advisers, L…2,790$244K0.07%+77013F-HRTimelineGroup
New Age Alpha Advisors, LLC2,784$243K0.01%new13F-HRTimeline
CAPTRUST FINANCIAL ADVISORS2,732$239K<0.01%-58013F-HRTimeline
GAMMA Investing LLC2,672$233K0.01%+1,02413F-HRTimeline
CIBC Asset Management Inc2,667$233K<0.01%new13F-HRTimeline
Sumitomo Mitsui Trust Group, Inc.in group Sumitomo Mitsui Trust Group, …2,560$224K<0.01%new13F-HRTimelineGroup
HIGHLAND CAPITAL MANAGEMENT, LLC2,462$215K0.01%new13F-HRTimeline
Swiss Life Asset Management Ltdin group Swiss Life Asset Management L…2,431$212K<0.01%new13F-HRTimelineGroup
State of Wyoming2,070$181K0.02%new13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…2,047$179K<0.01%-1,75413F-HRTimelineGroup
Smartleaf Asset Management LLC1,727$151K0.01%+32413F-HRTimeline
AlphaQuest LLC1,617$141K0.01%-113F-HRTimeline
KBC Group NVin group KBC Group NV1,574$137K<0.01%013F-HRTimelineGroup
QUADRANT CAPITAL GROUP LLC1,467$128K<0.01%+11513F-HRTimeline
Covestor Ltd1,437$125K0.07%+44713F-HRTimeline
GF FUND MANAGEMENT CO. LTD.1,227$107K<0.01%-11113F-HRTimeline
Truvestments Capital LLC1,161$101K0.02%+43913F-HRTimeline
Canton Hathaway, LLC1,000$87.3K0.02%new13F-HRTimeline
HANTZ FINANCIAL SERVICES, INC.951$83K<0.01%+65613F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
CFG Wealth Management Services, Inc.602$52.6K0.05%13F-HRTimeline
CWM, LLCin group CWM, LLC556$49K<0.01%013F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…559$48.8K<0.01%+1913F-HRTimelineGroup
SUMMIT SECURITIES GROUP LLC500$43.7K0.01%new13F-HRTimeline
Salomon & Ludwin, LLC436$36.7K<0.01%-613F-HRTimeline
Sterling Capital Management LLC378$33K<0.01%+23713F-HRTimeline
UMB Bank, n.a.333$29.1K<0.01%+7513F-HRTimelineThe filing omitted confidential holdings, a later amendment may add them.
FIFTH THIRD BANCORPin group FIFTH THIRD BANK, NATIONAL AS…327$28.6K<0.01%+2013F-HRTimelineGroup
Greenline Wealth Management LLC304$26.5K0.03%13F-HRTimeline
Farther Finance Advisors, LLC297$25.9K<0.01%+15613F-HRTimeline
ASSETMARK, INCin group ASSETMARK, INC285$24.9K<0.01%+513F-HRTimelineGroup
Sound Income Strategies, LLC284$23.3K<0.01%new13F-HRTimeline
Clearstead Advisors, LLC222$19.4K<0.01%+2213F-HRTimeline
Daiwa Securities Group Inc.in group Daiwa Securities Group Inc.190$17K<0.01%013F-HRTimelineGroup
Kemnay Advisory Services Inc.181$15.8K<0.01%new13F-HRTimeline
Larson Financial Group LLC171$14.9K<0.01%+1713F-HRTimeline
SIGNATUREFD, LLC163$14.2K<0.01%+1413F-HRTimeline
Matrix Trust Co143$12K<0.01%new13F-HRTimeline
MassMutual Private Wealth & Trust, FSB119$10.4K<0.01%013F-HRTimeline
Bare Financial Services, Inc110$9.61K<0.01%+7613F-HRTimeline
Parallel Advisors, LLC109$9.52K<0.01%+713F-HRTimeline
SageView Advisory Group, LLC106$9.26K<0.01%new13F-HRTimeline
DANSKE BANK A/S100$8.73K<0.01%013F-HRTimeline
MAI Capital Management97$8.47K<0.01%+1113F-HRTimeline
WPG Advisers, LLC96$8.38K0.01%+1813F-HRTimeline
ROTHSCHILD INVESTMENT LLC86$7.51K<0.01%+113F-HRTimeline
Parkside Financial Bank & Trust84$7.34K<0.01%+3913F-HRTimeline
BROWN BROTHERS HARRIMAN & COin group BROWN BROTHERS HARRIMAN & CO81$7.08K<0.01%013F-HRTimelineGroup
Bell Investment Advisors, Inc81$7.08K<0.01%013F-HRTimeline
Annis Gardner Whiting Capital Advisors,…76$6.64K<0.01%013F-HRTimeline
SBI Securities Co., Ltd.70$6.11K<0.01%new13F-HRTimeline
Sankala Group LLC60$5.53K<0.01%13F-HRTimeline
RAFFA WEALTH MANAGEMENT, LLC60$5.24K<0.01%013F-HRTimeline
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP46$4.02K<0.01%+2613F-HRTimelineGroup
Torren Management, LLC39$3.41K<0.01%13F-HRTimeline
HUNTINGTON NATIONAL BANKin group HUNTINGTON NATIONAL BANK35$3.06K<0.01%-413F-HRTimelineGroup
FARMERS & MERCHANTS INVESTMENTS INCin group FARMERS & MERCHANTS INVESTMEN…35$3.06K<0.01%013F-HRTimelineGroup
WOLFF WIESE MAGANA LLC35$3.06K<0.01%013F-HRTimeline
Marquette Asset Management, LLC28$2.45K<0.01%013F-HRTimeline
Versant Capital Management, Inc27$2.36K<0.01%013F-HRTimeline
PICTON MAHONEY ASSET MANAGEMENT25$2.18K<0.01%013F-HRTimeline
Elyxium Wealth, LLC22$1.92K<0.01%new13F-HRTimeline
Physician Wealth Advisors, Inc.21$1.83K<0.01%+1213F-HRTimeline
ORG Partners LLC19$1.66K<0.01%new13F-HRTimeline
Triumph Capital Management18$1.57K<0.01%new13F-HRTimeline
Ankerstar Wealth, LLC12$1.05K<0.01%13F-HRTimeline
Arax Advisory Partners10$874<0.01%-8213F-HRTimeline
Trust Co7$611<0.01%new13F-HRTimeline
FLAGSHIP HARBOR ADVISORS, LLC6$524<0.01%new13F-HRTimeline
GILPIN WEALTH MANAGEMENT, LLC5$437<0.01%13F-HRTimeline
DecisionPoint Financial, LLC4$350<0.01%013F-HRTimeline
Abound Wealth Management4$350<0.01%013F-HRTimeline
Kilter Group LLC4$350<0.01%013F-HRTimeline
TD Capital Management LLC4$349<0.01%new13F-HRTimeline
Root Financial Partners, LLC3$262<0.01%new13F-HRTimeline
HARBOUR INVESTMENTS, INC.2$175<0.01%new13F-HRTimeline
Hughes Financial Services, LLC2$175<0.01%new13F-HRTimeline
Keating Financial Advisory Services, In…2$175<0.01%13F-HRTimeline
Avion Wealth6$00%new13F-HRTimelineValue filed as zero, left out of ratios.