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Disclosery

PRLD PRELUDE THERAPEUTICS INC

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CMN (common), issuer CIK 1678660

50 managers (51 13F filers) reported a position in PRLD shares at 2025-06-30, 27,188,088 shares in all. 7 filers opened a position and 16 filers sold out during the quarter.

Managers
50
13F filers
51
New
7
Added
12
Reduced
23
Sold out
16
Shares held by filers
27,188,088

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q2 2025

Filers in the available 13F reports with a share position at 2025-06-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
ORBIMED ADVISORS LLCin group ORBIMED ADVISORS LLC10,909,256$8.83M0.22%013F-HRTimelineGroup
BAKER BROS. ADVISORS LPin group BAKER BROS. ADVISORS LP10,123,824$8.19M0.08%013F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC932,570$754K<0.01%-76,63413F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/927,608$743K<0.01%-48,53913F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC581,800$471K<0.01%-74,90013F-HRTimeline
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC540,565$436K<0.01%+11,23813F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.432,559$350K<0.01%-615,16613F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding379,977$308K-64,090Timeline
MORGAN STANLEYin group MORGAN STANLEY284,382$230K<0.01%-18,39713F-HRTimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC248,423$201K<0.01%+101,65313F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC217,568$176K<0.01%-187,38713F-HRTimelineGroup
CANTOR FITZGERALD, L. P.in group CANTOR FITZGERALD, L. P.211,859$171K<0.01%new13F-HRTimelineGroup
TD Asset Management Inc160,652$130K<0.01%013F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC149,178$121K<0.01%-6,03713F-HRTimelineGroup
UBS Group AGin group UBS Group AG104,204$84.3K<0.01%+8,04813F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP97,592$79K<0.01%-188,45413F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC91,753$74.3K<0.01%new13F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC88,500$71.6K<0.01%013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co80,845$65.4K<0.01%-33,20513F-HRTimelineGroup
Shay Capital LLC75,000$60.7K0.01%new13F-HRTimeline
GSA CAPITAL PARTNERS LLP71,378$58K<0.01%new13F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …69,252$56.1K<0.01%013F-HRTimelineGroup
Y-Intercept (Hong Kong) Ltd47,788$38.7K<0.01%new13F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC43,647$35.3K<0.01%+9,82413F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd42,573$34.5K<0.01%+17,87313F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP41,747$33.8K<0.01%new13F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…39,977$32.4K<0.01%-37,89313F-HRTimelineGroup
NORTHERN TRUST CORPin group NORTHERN TRUST CORP38,127$30.9K<0.01%-78,78013F-HRTimelineGroup
Cerity Partners LLCin group Cerity Partners LLC36,393$29.5K<0.01%+1,82813F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC33,625$27.2K<0.01%+33,59113F-HRTimelineGroup
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC17,411$13.9K<0.01%-3,21913F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…16,799$13.6K<0.01%+3,21313F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/11,293$9.14K<0.01%-4,15313F-HRTimelineGroup
FMR LLCin group FMR LLC11,167$9.04K<0.01%-9,07113F-HRTimelineGroup
BARCLAYS PLCin group BARCLAYS PLC8,602$6.96K<0.01%-14,54313F-HR/ATimelineGroup
CITIGROUP INCin group CITIGROUP INC4,718$3.82K<0.01%-4,58213F-HRTimelineGroup
CWM, LLCin group CWM, LLC4,014$3K<0.01%+66813F-HRTimelineGroup
SBI Securities Co., Ltd.2,741$2.22K<0.01%013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA2,827$2K<0.01%-51713F-HR/ATimelineGroup
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO1,949$1.58K<0.01%-21,83113F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC1,634$1.32K<0.01%+1,23413F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…1,180$956<0.01%-1213F-HRTimelineGroup
GROUP ONE TRADING LLC500$405<0.01%013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN297$240<0.01%-7,61513F-HRTimelineGroup
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…148$120<0.01%+13913F-HRTimelineGroup
Essential Partners LLC87$70<0.01%13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS52$42<0.01%-19,61613F-HRTimelineGroup
IFP Advisors, Inc34$28<0.01%new13F-HRTimeline
True Wealth Design, LLC13$11<0.01%+313F-HRTimeline
CONCOURSE FINANCIAL GROUP SECURITIES, I…0$0013F-HRTimelineValue filed as zero, left out of ratios. Amount filed as zero, left out of ratios.