Skip to content
Disclosery

PLX PROTALIX BIOTHERAPEUTICS INC

Follow

COMMON STOCK (common), issuer CIK 1006281

83 managers (83 13F filers) reported a position in PLX shares at 2025-12-31, 14,904,487 shares in all. 12 filers opened a position and 5 filers sold out during the quarter.

Managers
83
13F filers
83
New
12
Added
29
Reduced
22
Sold out
5
Shares held by filers
14,904,487

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
BlackRock, Inc.in group BlackRock, Inc.3,647,106$6.56M<0.01%+96,07813F-HRTimelineGroup
Opaleye Management Inc.2,478,176$4.46M0.59%-102,38013F-HR/ATimeline
RENAISSANCE TECHNOLOGIES LLC1,263,300$2.27M<0.01%-52,10013F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP865,708$1.56M<0.01%-36,75113F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC830,054$1.49M<0.01%+10,27713F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP585,261$1.05M<0.01%+86,71413F-HRTimelineGroup
Stratos Wealth Partners, LTD.in group Stratos Wealth Partners, LTD.500,000$900K0.01%013F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC488,552$879K<0.01%+24,13113F-HRTimelineGroup
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC317,628$572K<0.01%+280,32213F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC289,917$522K<0.01%new13F-HRTimelineGroup
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC262,809$473K<0.01%+111,98013F-HR/ATimelineGroup
UBS Group AGin group UBS Group AG262,520$473K<0.01%+72,24413F-HRTimelineGroup
Connor, Clark & Lunn Investment Managem…232,093$418K<0.01%-168,30513F-HRTimeline
Main Street Financial Solutions, LLC214,100$385K0.03%+85,00013F-HRTimeline
Bank of New York Mellon Corpin group Bank of New York Mellon Corp210,867$380K<0.01%+72,31913F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC189,100$340K0.01%013F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co175,070$315K<0.01%013F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC171,772$309K<0.01%013F-HRTimeline
EVERGREEN CAPITAL MANAGEMENT LLC171,338$308K0.01%013F-HRTimeline
Round Rock Advisors LLC155,102$279K0.04%new13F-HR/ATimeline
Diametric Capital, LP138,929$250K0.07%-41,05513F-HRTimeline
MORGAN STANLEYin group MORGAN STANLEY131,987$238K<0.01%+60,95013F-HR/ATimelineGroup
BARCLAYS PLCin group BARCLAYS PLC112,849$203K<0.01%+11,05113F-HRTimelineGroup
Nuveen, LLCin group TIAA90,188$162K<0.01%013F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN79,002$142K<0.01%+36,17113F-HRTimelineGroup
LAZARD ASSET MANAGEMENT LLCin group LAZARD ASSET MANAGEMENT LLC71,393$129K<0.01%new13F-HRTimelineGroup
HRT FINANCIAL LP64,610$116K<0.01%new13F-HRTimeline
Orin Green Financial, LLC61,433$111K0.04%+23313F-HRTimeline
Invesco Ltd.in group Invesco Ltd.50,563$91K<0.01%+5,56013F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/46,352$83.4K<0.01%+26,23313F-HRTimelineGroup
RHUMBLINE ADVISERS44,369$79.9K<0.01%-20,82513F-HRTimeline
TWO SIGMA SECURITIES, LLC39,811$71.7K0.01%new13F-HRTimeline
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…38,518$69.3K<0.01%-34,40413F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/35,278$64K<0.01%013F-HRTimeline
XTX Topco Ltdin group XTX Topco Ltd34,296$61.7K<0.01%-51,54513F-HRTimelineGroup
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…33,246$59.8K<0.01%+99313F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC31,133$56K<0.01%-11513F-HRTimeline
NEW YORK STATE COMMON RETIREMENT FUND31,100$56K<0.01%-10,20013F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO30,874$55.6K<0.01%+88313F-HRTimelineGroup
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP28,744$51.5K<0.01%+11,71613F-HRTimelineGroup
Aptus Capital Advisors, LLC26,610$47.9K<0.01%+88313F-HRTimeline
EARNED WEALTH ADVISORS, LLC25,975$46.8K<0.01%013F-HR/ATimeline
Smartleaf Asset Management LLC25,975$45.2K<0.01%new13F-HRTimeline
PRELUDE CAPITAL MANAGEMENT, LLC22,243$40K<0.01%-27,54813F-HRTimeline
State of Alaska, Department of Revenue21,831$39K<0.01%new13F-HRTimeline
Lido Advisors, LLCin group Lido Advisors, LLC15,554$34.5K<0.01%013F-HRTimelineGroup
MARSHALL WACE, LLPin group MARSHALL WACE, LLP19,079$34.3K<0.01%new13F-HRTimelineGroup
Police & Firemen's Retirement System of…18,554$33.4K<0.01%013F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …18,498$33.3K<0.01%-5,55613F-HRTimelineGroup
SG Americas Securities, LLC17,155$31K<0.01%new13F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS17,021$30.6K<0.01%+1,80613F-HRTimelineGroup
R Squared Ltd14,632$26.3K0.01%new13F-HRTimeline
ProShare Advisors LLC13,137$23.6K<0.01%+1,21513F-HRTimeline
TWO SIGMA ADVISERS, LPin group TWO SIGMA INVESTMENTS, LP12,900$23.2K<0.01%+2,60013F-HRTimelineGroup
Altshuler Shaham Ltd12,142$21.9K<0.01%013F-HRTimeline
Cascade Financial Partners, LLC12,000$21.6K<0.01%-5,00013F-HRTimeline
ALLIANCEBERNSTEIN L.P.11,720$21.1K<0.01%013F-HRTimeline
Equitable Holdings, Inc.in group Equitable Holdings, Inc.11,150$20.1K<0.01%new13F-HRTimelineGroup
LPL Financial LLC10,291$18.5K<0.01%013F-HRTimeline
HARBOUR INVESTMENT MANAGEMENT LLC10,100$18.2K0.01%013F-HRTimeline
Kestra Advisory Services, LLCin group Kestra Advisory Services, LLC10,000$18K<0.01%-1,00013F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…7,267$13.1K<0.01%-19813F-HRTimelineGroup
Legal & General Group Plcin group Legal & General Group Plc7,201$13K<0.01%-55613F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…7,119$12.8K<0.01%013F-HRTimelineGroup
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…6,233$11.2K<0.01%+72013F-HRTimelineGroup
TD Waterhouse Canada Inc.6,000$10.7K<0.01%013F-HRTimeline
CALIFORNIA STATE TEACHERS RETIREMENT SY…4,443$8K<0.01%+9013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA3,404$6K<0.01%+2,33113F-HRTimelineGroup
FMR LLCin group FMR LLC2,315$4.17K<0.01%+1,87713F-HRTimelineGroup
AMALGAMATED BANK2,269$4K<0.01%-11213F-HRTimeline
CITIGROUP INCin group CITIGROUP INC1,634$2.94K<0.01%-4,98013F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.1,200$2.16K<0.01%+50013F-HRTimelineGroup
Investment Research & Advisory Group, I…1,000$1.8K<0.01%013F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\846$1.52K<0.01%-64,77113F-HRTimelineGroup
Sterling Capital Management LLC453$815<0.01%+28413F-HRTimeline
GAMMA Investing LLC355$639<0.01%new13F-HRTimeline
Activest Wealth Management300$540<0.01%013F-HRTimeline
Federation des caisses Desjardins du Qu…250$450<0.01%013F-HRTimeline
Y.D. More Investments Ltdin group Y.D. More Investments Ltd220$383<0.01%013F-HRTimelineGroup
Arax Advisory Partners39$71<0.01%-25713F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…20$36<0.01%-1513F-HRTimelineGroup
SBI Securities Co., Ltd.1$2<0.01%-20013F-HRTimeline
CWM, LLCin group CWM, LLC203$00%+4013F-HRTimelineGroupValue filed as zero, left out of ratios.