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Disclosery

PLX PROTALIX BIOTHERAPEUTICS INC

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COMMON STOCK (common), issuer CIK 1006281

77 managers (77 13F filers) reported a position in PLX shares at 2025-09-30, 13,927,516 shares in all. 17 filers opened a position and 3 filers sold out during the quarter.

Managers
77
13F filers
77
New
17
Added
17
Reduced
21
Sold out
3
Shares held by filers
13,927,516

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q3 2025

Filers in the available 13F reports with a share position at 2025-09-30, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
BlackRock, Inc.in group BlackRock, Inc.3,551,028$7.88M<0.01%+181,35813F-HRTimelineGroup
Opaleye Management Inc.2,580,556$5.73M0.81%new13F-HRTimeline
RENAISSANCE TECHNOLOGIES LLC1,315,400$2.92M<0.01%-299,60313F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP902,459$2M<0.01%-177,26413F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC819,777$1.82M<0.01%-6,55613F-HRTimelineGroup
Stratos Wealth Partners, LTD.in group Stratos Wealth Partners, LTD.500,000$1.11M0.01%+150,00013F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP498,547$1.11M<0.01%+54,30813F-HRTimelineGroup
VANGUARD GROUP INCin group VANGUARD GROUP INC464,421$1.03M<0.01%-20,37713F-HRTimelineGroup
Connor, Clark & Lunn Investment Managem…400,398$889K<0.01%-95,81813F-HRTimeline
UBS Group AGin group UBS Group AG190,276$422K<0.01%+115,12613F-HRTimelineGroup
BRIDGEWAY CAPITAL MANAGEMENT, LLC189,100$420K0.01%013F-HRTimeline
Diametric Capital, LP179,984$400K0.15%+36,71213F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co175,070$389K<0.01%013F-HRTimelineGroup
COMMONWEALTH EQUITY SERVICES, LLC171,772$381K<0.01%-25,02513F-HRTimeline
EVERGREEN CAPITAL MANAGEMENT LLC171,338$380K0.01%013F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC150,829$335K<0.01%+48,65113F-HRTimelineGroup
Bank of New York Mellon Corpin group Bank of New York Mellon Corp138,548$308K<0.01%+4,26113F-HRTimelineGroup
Main Street Financial Solutions, LLC129,100$287K0.02%new13F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC101,798$226K<0.01%-25,16513F-HR/ATimelineGroup
Nuveen, LLCin group TIAA90,188$200K<0.01%013F-HRTimelineGroup
XTX Topco Ltdin group XTX Topco Ltd85,841$191K0.01%+12,16613F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPin group SUSQUEHANNA INTERNATIONAL GRO…72,922$162K<0.01%-225,64513F-HRTimelineGroup
MORGAN STANLEYin group MORGAN STANLEY71,037$158K<0.01%-391,00613F-HR/ATimelineGroup
WOLVERINE TRADING, LLC70,394$152K<0.01%+45,88613F-HRTimeline
DEUTSCHE BANK AG\in group DEUTSCHE BANK AG\65,617$146K<0.01%new13F-HRTimelineGroup
RHUMBLINE ADVISERS65,194$145K<0.01%-4,60213F-HRTimeline
Orin Green Financial, LLC61,200$136K0.05%013F-HRTimeline
PRELUDE CAPITAL MANAGEMENT, LLC49,791$111K0.01%-6,26413F-HRTimeline
Invesco Ltd.in group Invesco Ltd.45,003$99.9K<0.01%-13813F-HRTimelineGroup
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN42,831$95.1K<0.01%+6,79713F-HRTimelineGroup
NEW YORK STATE COMMON RETIREMENT FUND41,300$91.7K<0.01%-27,70013F-HRTimeline
State of Wyoming39,018$86.6K0.01%new13F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC37,306$82.8K<0.01%new13F-HRTimelineGroup
PRICE T ROWE ASSOCIATES INC /MD/35,278$79K<0.01%013F-HRTimeline
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.in group Mirae Asset Global Investment…32,253$71.6K<0.01%-5,82213F-HRTimelineGroup
INTECH INVESTMENT MANAGEMENT LLC31,248$69.4K<0.01%-5,24213F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO29,991$66.6K<0.01%-4,55413F-HR/ATimelineGroup
EARNED WEALTH ADVISORS, LLC25,975$57.7K0.01%-113F-HRTimeline
Aptus Capital Advisors, LLC25,727$57.1K<0.01%+87413F-HRTimeline
MANUFACTURERS LIFE INSURANCE COMPANY, T…in group MANUFACTURERS LIFE INSURANCE …24,054$53.4K<0.01%new13F-HRTimelineGroup
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/20,119$44.7K<0.01%-1,77313F-HR/ATimelineGroup
Police & Firemen's Retirement System of…18,554$41.2K<0.01%013F-HRTimeline
Cascade Financial Partners, LLC17,000$37.7K<0.01%013F-HRTimeline
DIMENSIONAL FUND ADVISORS LPin group DIMENSIONAL FUND ADVISORS LP17,028$37.5K<0.01%-28,54313F-HRTimelineGroup
Virtu Financial LLCin group Virtu Financial LLC16,530$37K<0.01%new13F-HRTimelineGroup
Lido Advisors, LLCin group Lido Advisors, LLC15,554$34.5K<0.01%013F-HRTimelineGroup
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS15,215$33.8K<0.01%+8,49813F-HRTimelineGroup
Altshuler Shaham Ltd12,142$27K<0.01%013F-HRTimeline
ProShare Advisors LLC11,922$26.5K<0.01%-2,37513F-HRTimeline
ALLIANCEBERNSTEIN L.P.11,720$26K<0.01%013F-HRTimeline
Kestra Advisory Services, LLCin group Kestra Advisory Services, LLC11,000$24.4K<0.01%new13F-HRTimelineGroup
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding10,300$22.9K-61,237Timeline
LPL Financial LLC10,291$22.8K<0.01%new13F-HRTimeline
HARBOUR INVESTMENT MANAGEMENT LLC10,100$22.4K0.01%013F-HRTimeline
Legal & General Group Plcin group Legal & General Group Plc7,757$17.2K<0.01%013F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…7,465$16.6K<0.01%new13F-HRTimelineGroup
Ameritas Investment Partners, Inc.in group Ameritas Investment Partners,…7,119$15.8K<0.01%013F-HRTimelineGroup
CITIGROUP INCin group CITIGROUP INC6,614$14.7K<0.01%-18,14213F-HRTimelineGroup
TD Waterhouse Canada Inc.6,000$14K<0.01%013F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…5,513$12.2K<0.01%+5,38613F-HRTimelineGroup
CALIFORNIA STATE TEACHERS RETIREMENT SY…4,353$9.66K<0.01%+313F-HRTimeline
SIMPLEX TRADING, LLC2,942$6K<0.01%new13F-HRTimeline
Truvestments Capital LLC2,458$5.46K<0.01%013F-HRTimeline
AMALGAMATED BANK2,381$5K<0.01%013F-HRTimeline
Investment Research & Advisory Group, I…1,000$2.22K<0.01%013F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA1,073$2K<0.01%+78013F-HRTimelineGroup
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.700$1.29K<0.01%013F-HRTimelineGroup
FMR LLCin group FMR LLC438$972<0.01%new13F-HRTimelineGroup
Activest Wealth Management300$666<0.01%013F-HRTimeline
Arax Advisory Partners296$658<0.01%new13F-HRTimeline
Federation des caisses Desjardins du Qu…250$555<0.01%013F-HRTimeline
Y.D. More Investments Ltdin group Y.D. More Investments Ltd220$488<0.01%013F-HRTimelineGroup
SBI Securities Co., Ltd.201$446<0.01%+113F-HRTimeline
Sterling Capital Management LLC169$375<0.01%+113F-HRTimeline
PNC Financial Services Group, Inc.in group PNC Financial Services Group,…35$78<0.01%new13F-HRTimelineGroup
Steward Partners Investment Advisory, L…25$56<0.01%new13F-HRTimeline
CWM, LLCin group CWM, LLC163$00%new13F-HRTimelineGroupValue filed as zero, left out of ratios.