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ORACLE INVESTMENT MANAGEMENT INC

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13F filer, CIK 1012622, GREENWICH, CT

ORACLE INVESTMENT MANAGEMENT INC reported $160,065,372 across 20 holdings for the quarter ended 2025-09-30, in a 13F-HR filed 2025-11-19. Its ten largest share positions make up 97.84% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001012622-25-000003

Period
2025-09-30
Reported value
$160M
Holdings
20
Top 10 weight
97.84%
New
8
Sold out
2

Largest buys vs the previous quarter

SecurityShares changeApprox. value
CNCnew+110,300$3.94M
TDOCadded+324,416$2.51M
NVAXnew+243,000$2.11M
PSNLnew+229,435$1.5M
BHVNadded+66,820$1M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
WGSreduced-32,500-$3.5M
CAVAreduced-1,500-$90.6K

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q3 2025

Share positions as resolved from 13F-HR 0001012622-25-000003, largest first. % of portfolio is the value over $143,308,479, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
WGSGENEDX HOLDINGS CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: 1,126,607 shares; 2024Q2: 1,105,768 shares; 2024Q3: 1,045,768 shares; 2024Q4: 1,023,468 shares; 2025Q1: 969,954 shares; 2025Q2: 922,454 shares; 2025Q3: 889,954 shares 889,954$95.9M66.91%-32,500Timeline
BHVNBIOHAVEN LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: 804,850 shares; 2024Q2: 700,450 shares; 2024Q3: 705,250 shares; 2024Q4: 851,770 shares; 2025Q1: 665,945 shares; 2025Q2: 673,166 shares; 2025Q3: 739,986 shares 739,986$11.1M7.75%+66,820Timeline
ARDXARDELYX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: 2,039,700 shares; 2024Q2: 1,488,131 shares; 2024Q3: 1,369,200 shares; 2024Q4: 2,089,431 shares; 2025Q1: 2,404,438 shares; 2025Q2: 1,430,728 shares; 2025Q3: 1,503,826 shares 1,503,826$8.29M5.78%+73,098Timeline
TDOCTELADOC HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: not reported; 2024Q2: not reported; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 565,900 shares; 2025Q2: 381,000 shares; 2025Q3: 705,416 shares 705,416$5.45M3.8%+324,416Timeline
PLTRPALANTIR TECHNOLOGIES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: not reported; 2024Q2: not reported; 2024Q3: 27,500 shares; 2024Q4: 28,500 shares; 2025Q1: 29,500 shares; 2025Q2: 29,500 shares; 2025Q3: 29,500 shares 29,500$5.38M3.76%0Timeline
CNCCENTENE CORP DELQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: not reported; 2024Q2: not reported; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 110,300 shares 110,300$3.94M2.75%newTimeline
QDELQUIDELORTHO CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: 157,201 shares; 2024Q2: 118,291 shares; 2024Q3: 118,291 shares; 2024Q4: 118,291 shares; 2025Q1: 118,291 shares; 2025Q2: 118,291 shares; 2025Q3: 118,291 shares 118,291$3.48M2.43%0Timeline
FORAFORIAN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: 1,355,807 shares; 2024Q2: 1,356,107 shares; 2024Q3: 1,356,107 shares; 2024Q4: 1,366,107 shares; 2025Q1: 1,366,107 shares; 2025Q2: 1,366,107 shares; 2025Q3: 1,366,107 shares 1,366,107$3.07M2.14%0Timeline
NVAXNOVAVAX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: not reported; 2024Q2: not reported; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 243,000 shares 243,000$2.11M1.47%newTimeline
PSNLPERSONALIS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: not reported; 2024Q2: not reported; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 229,435 shares 229,435$1.5M1.04%newTimeline
CAVACAVA GROUP INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: 17,600 shares; 2024Q2: 18,600 shares; 2024Q3: 18,600 shares; 2024Q4: 18,600 shares; 2025Q1: 18,600 shares; 2025Q2: 18,600 shares; 2025Q3: 17,100 shares 17,100$1.03M0.72%-1,500Timeline
KOIDKRANESHARES TRUSTQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: not reported; 2024Q2: not reported; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 22,400 shares 22,400$719K0.5%newTimeline
SGMOQSANGAMO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: not reported; 2024Q2: not reported; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 1,004,724 shares 1,004,724$677K0.47%newTimeline
BIIBBIOGEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: 2,412 shares; 2024Q2: 2,412 shares; 2024Q3: 2,412 shares; 2024Q4: 2,412 shares; 2025Q1: 2,412 shares; 2025Q2: 2,412 shares; 2025Q3: 2,412 shares 2,412$338K0.24%0Timeline
TSLATESLA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: not reported; 2024Q2: not reported; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 500 shares 500$222K0.16%newTimeline
BDSXBIODESIX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q4: restricted; 2024Q1: not reported; 2024Q2: not reported; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 15,000 shares 15,000$113K0.08%newTimeline

Options

Puts and calls, as filed. The amount and value describe the underlying shares, not the option premium, so they stay out of % of portfolio (H5).

SecurityTypeAmountValueChange
NOVAVAX INCNOVAVAX INC COM NEWcall635,000$5.51Mnew
BIOHAVEN LTDBIOHAVEN LTD COMcall275,000$4.13M+75,000
TELADOC HEALTH INCTELADOC HEALTH INC OPTIONcall470,500$3.64M-279,600
ARDELYX INCARDELYX INC COMcall632,800$3.49M-547,000

Sold out in Q3 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
GENEDX HOLDINGS CORPGENEDX HOLDINGS CORP100,000$9.23Mcall
SPRINGWORKS THERAPEUTICS INCSPRINGWORKS THERAPEUTICS INC150,000$7.05Mcall

How Q3 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001012622-25-000003 base2025-11-19acceptance time not in the bulk data set