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ORACLE INVESTMENT MANAGEMENT INC

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13F filer, CIK 1012622, GREENWICH, CT

ORACLE INVESTMENT MANAGEMENT INC reported $198,208,397 across 17 holdings for the quarter ended 2025-03-31, in a 13F-HR filed 2025-05-15. Its ten largest share positions make up 99.79% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001085146-25-003330

Period
2025-03-31
Reported value
$198M
Holdings
17
Top 10 weight
99.79%
New
5
Sold out
7

Largest buys vs the previous quarter

SecurityShares changeApprox. value
SPRINGWORKS THERAPEUTICS INCadded+276,578$12.2M
TDOCnew+565,900$4.5M
ARDXadded+315,007$1.55M
RXRXnew+120,000$635K
PLTRadded+1,000$84.4K

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
WGSreduced-53,514-$4.74M
BHVNreduced-185,825-$4.47M
BCRXexited-535,558-$4.03M
PHATexited-145,064-$1.18M
PACBexited-279,638-$512K

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q1 2025

Share positions as resolved from 13F-HR 0001085146-25-003330, largest first. % of portfolio is the value over $153,602,903, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
WGSGENEDX HOLDINGS CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: 1,126,607 shares; 2024Q2: 1,105,768 shares; 2024Q3: 1,045,768 shares; 2024Q4: 1,023,468 shares; 2025Q1: 969,954 shares 969,954$85.9M55.93%-53,514Timeline
SPRINGWORKS THERAPEUTICS INCSPRINGWORKS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: 421,583 shares; 2024Q2: 233,200 shares; 2024Q3: 34,200 shares; 2024Q4: 254,773 shares; 2025Q1: 531,351 shares 531,351$23.4M15.27%+276,578
BHVNBIOHAVEN LTDQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: 804,850 shares; 2024Q2: 700,450 shares; 2024Q3: 705,250 shares; 2024Q4: 851,770 shares; 2025Q1: 665,945 shares 665,945$16M10.42%-185,825Timeline
ARDXARDELYX INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: 2,039,700 shares; 2024Q2: 1,488,131 shares; 2024Q3: 1,369,200 shares; 2024Q4: 2,089,431 shares; 2025Q1: 2,404,438 shares 2,404,438$11.8M7.69%+315,007Timeline
TDOCTELADOC HEALTH INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: not reported; 2024Q2: not reported; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 565,900 shares 565,900$4.5M2.93%newTimeline
QDELQUIDELORTHO CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: 157,201 shares; 2024Q2: 118,291 shares; 2024Q3: 118,291 shares; 2024Q4: 118,291 shares; 2025Q1: 118,291 shares 118,291$4.14M2.69%0Timeline
FORAFORIAN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: 1,355,807 shares; 2024Q2: 1,356,107 shares; 2024Q3: 1,356,107 shares; 2024Q4: 1,366,107 shares; 2025Q1: 1,366,107 shares 1,366,107$2.73M1.78%0Timeline
PLTRPALANTIR TECHNOLOGIES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: not reported; 2024Q2: not reported; 2024Q3: 27,500 shares; 2024Q4: 28,500 shares; 2025Q1: 29,500 shares 29,500$2.49M1.62%+1,000Timeline
CAVACAVA GROUP INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: 17,600 shares; 2024Q2: 18,600 shares; 2024Q3: 18,600 shares; 2024Q4: 18,600 shares; 2025Q1: 18,600 shares 18,600$1.61M1.05%0Timeline
RXRXRECURSION PHARMACEUTICALS INQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: not reported; 2024Q2: not reported; 2024Q3: not reported; 2024Q4: not reported; 2025Q1: 120,000 shares 120,000$635K0.41%newTimeline
BIIBBIOGEN INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2023Q2: restricted; 2023Q3: restricted; 2023Q4: restricted; 2024Q1: 2,412 shares; 2024Q2: 2,412 shares; 2024Q3: 2,412 shares; 2024Q4: 2,412 shares; 2025Q1: 2,412 shares 2,412$330K0.21%0Timeline

Options

Puts and calls, as filed. The amount and value describe the underlying shares, not the option premium, so they stay out of % of portfolio (H5).

SecurityTypeAmountValueChange
SPDR SERIES TRUSTSPDR SERIES TRUST ST STR SP BIOTcall280,000$22.7Mnew
VIKING THERAPEUTICS INCVIKING THERAPEUTICS INC CALLcall336,700$8.13Mnew
ARDELYX INCARDELYX INC COMcall1,133,500$5.57M+548,800
BIOHAVEN LTDBIOHAVEN LTD COMcall161,900$3.89M-38,100
PELOTON INTERACTIVE INCPELOTON INTERACTIVE INC CALLcall500,000$3.16Mnew
TELADOC HEALTH INCTELADOC HEALTH INC OPTIONcall144,300$1.15M-153,400

Sold out in Q1 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
SELECT SECTOR SPDR TRSELECT SECTOR SPDR TR115,000$15.8Mput
BCRXBIOCRYST PHARMACEUTICALS INC535,558$4.03Mshares
NOVAVAX INCNOVAVAX INC466,000$3.75Mcall
SPRINGWORKS THERAPEUTICS INCSPRINGWORKS THERAPEUTICS INC55,800$2.02Mcall
PHATPHATHOM PHARMACEUTICALS INC145,064$1.18Mshares
PACBPACIFIC BIOSCIENCES CALIF IN279,638$512Kshares
EYPTEYEPOINT INC32,500$242Kshares

How Q1 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001085146-25-003330 base2025-05-15acceptance time not in the bulk data set