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Nextech Invest Ltd.

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13F filer, CIK 1595430, Zurich, Switzerland

Nextech Invest Ltd. reported $1,034,422,154 across 16 holdings for the quarter ended 2025-12-31, in a 13F-HR filed 2026-02-17. Its ten largest share positions make up 95.46% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001595430-26-000002

Period
2025-12-31
Reported value
$1.03B
Holdings
16
Top 10 weight
95.46%
New
2
Sold out
1

Largest buys vs the previous quarter

SecurityShares changeApprox. value
ENGNnew+2,124,943$19.2M
TNGXadded+1,732,101$15.3M
RLAYadded+855,097$7.23M
GLUEnew+279,237$4.38M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
ARVNreduced-869,000-$10.3M
KYMRreduced-62,013-$4.83M
BOLDexited-1,228,069-$1.51M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q4 2025

Share positions as resolved from 13F-HR 0001595430-26-000002, largest first. % of portfolio is the value over $1,034,422,154, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
RVMDREVOLUTION MEDICINES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not loaded; 2025Q1: 7,601,087 shares; 2025Q2: 7,601,087 shares; 2025Q3: 7,601,087 shares; 2025Q4: 7,601,087 shares 7,601,087$605M58.53%0Timeline
TYRATYRA BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not loaded; 2025Q1: 4,055,861 shares; 2025Q2: 4,055,861 shares; 2025Q3: 4,055,861 shares; 2025Q4: 4,055,861 shares 4,055,861$107M10.31%0Timeline
TNGXTANGO THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not loaded; 2025Q1: 5,533,980 shares; 2025Q2: 5,533,980 shares; 2025Q3: 5,533,980 shares; 2025Q4: 7,266,081 shares 7,266,081$64.4M6.22%+1,732,101Timeline
ORICORIC PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not loaded; 2025Q1: 5,285,714 shares; 2025Q2: 7,162,637 shares; 2025Q3: 7,162,637 shares; 2025Q4: 7,162,637 shares 7,162,637$58.6M5.66%0Timeline
RLAYRELAY THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not loaded; 2025Q1: 3,846,409 shares; 2025Q2: 3,846,409 shares; 2025Q3: 3,846,409 shares; 2025Q4: 4,701,506 shares 4,701,506$39.8M3.85%+855,097Timeline
ZYMEZYMEWORKS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not loaded; 2025Q1: 1,113,946 shares; 2025Q2: 1,113,946 shares; 2025Q3: 1,113,946 shares; 2025Q4: 1,113,946 shares 1,113,946$29.3M2.84%0Timeline
ALMSALUMIS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not loaded; 2025Q1: 1,476,998 shares; 2025Q2: 2,915,998 shares; 2025Q3: 2,915,998 shares; 2025Q4: 2,915,998 shares 2,915,998$28.5M2.75%0Timeline
KYMRKYMERA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not loaded; 2025Q1: not reported; 2025Q2: 340,909 shares; 2025Q3: 340,909 shares; 2025Q4: 278,896 shares 278,896$21.7M2.1%-62,013Timeline
ENGNENGENE HOLDINGS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not loaded; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 2,124,943 shares 2,124,943$19.2M1.85%newTimeline
MERSANA THERAPEUTICS INCMERSANA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not loaded; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: 482,689 shares; 2025Q4: 482,689 shares 482,689$14M1.35%0
CGEMCULLINAN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not loaded; 2025Q1: 1,141,145 shares; 2025Q2: 1,141,145 shares; 2025Q3: 1,141,145 shares; 2025Q4: 1,141,145 shares 1,141,145$11.8M1.14%0Timeline
CNTXCONTEXT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not loaded; 2025Q1: 7,419,355 shares; 2025Q2: 7,419,355 shares; 2025Q3: 7,419,355 shares; 2025Q4: 7,419,355 shares 7,419,355$10.9M1.05%0Timeline
SPRYARS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not loaded; 2025Q1: 936,729 shares; 2025Q2: 741,729 shares; 2025Q3: 660,703 shares; 2025Q4: 660,703 shares 660,703$7.7M0.74%0Timeline
ARVNARVINAS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not loaded; 2025Q1: 1,408,394 shares; 2025Q2: 1,408,394 shares; 2025Q3: 1,408,394 shares; 2025Q4: 539,394 shares 539,394$6.4M0.62%-869,000Timeline
SLNSILENCE THERAPEUTICS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not loaded; 2025Q1: 952,400 shares; 2025Q2: 952,400 shares; 2025Q3: 952,400 shares; 2025Q4: 952,400 shares 952,400$5.79M0.56%0Timeline
GLUEMONTE ROSA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2024Q1: restricted; 2024Q2: restricted; 2024Q3: not loaded; 2024Q4: not loaded; 2025Q1: not reported; 2025Q2: not reported; 2025Q3: not reported; 2025Q4: 279,237 shares 279,237$4.38M0.42%newTimeline

Sold out in Q4 2025

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
BOLDBOUNDLESS BIO INC1,228,069$1.51Mshares

How Q4 2025 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001595430-26-000002 base2026-02-17acceptance time not in the bulk data set