FMR LLC in group FMR LLC More: the full row for FMR LLC 8,787,052 $61.5M <0.01% +8,566,052 13F-HR Timeline Group Sanofi More: the full row for Sanofi 2,708,559 $19M 7.28% new 13F-HR Timeline VANGUARD GROUP INC in group VANGUARD GROUP INC More: the full row for VANGUARD GROUP INC 2,415,244 $16.9M <0.01% +1,358,322 13F-HR Timeline Group PRICE T ROWE ASSOCIATES INC /MD/ More: the full row for PRICE T ROWE ASSOCIATES INC /MD/ 1,798,782 $12.6M <0.01% new 13F-HR Timeline ExodusPoint Capital Management, LP More: the full row for ExodusPoint Capital Management, LP 1,516,833 $10.6M 0.15% new 13F-HR Timeline Logos Global Management LP More: the full row for Logos Global Management LP 950,000 $6.65M 0.66% new 13F-HR Timeline CITADEL ADVISORS LLC in group CITADEL ADVISORS LLC More: the full row for CITADEL ADVISORS LLC 943,144 $6.6M 0.01% new 13F-HR Timeline Group BlackRock, Inc. in group BlackRock, Inc. More: the full row for BlackRock, Inc. 681,185 $4.77M <0.01% +258,427 13F-HR Timeline Group Blue Owl Capital Holdings LP More: the full row for Blue Owl Capital Holdings LP 550,000 $3.85M 1.2% new 13F-HR Timeline GEODE CAPITAL MANAGEMENT, LLC in group GEODE CAPITAL MANAGEMENT, LLC More: the full row for GEODE CAPITAL MANAGEMENT, LLC 513,665 $3.6M <0.01% +283,390 13F-HR Timeline Group Occam Crest Management LP More: the full row for Occam Crest Management LP 498,498 $3.49M 2.37% 13F-HR Timeline Monashee Investment Management LLC More: the full row for Monashee Investment Management LLC 300,000 $2.1M 1.05% new 13F-HR Timeline Burkehill Global Management, LP More: the full row for Burkehill Global Management, LP 300,000 $2.1M 0.12% new 13F-HR Timeline MORGAN STANLEY in group MORGAN STANLEY More: the full row for MORGAN STANLEY 294,857 $2.06M <0.01% +93,763 13F-HR/A Timeline Group IRIDIAN ASSET MANAGEMENT LLC/CT More: the full row for IRIDIAN ASSET MANAGEMENT LLC/CT 275,086 $1.93M 0.76% new 13F-HR Timeline SOUTHPORT MANAGEMENT, L.L.C. in group SOUTHPORT MANAGEMENT, L.L.C. More: the full row for SOUTHPORT MANAGEMENT, L.L.C. 272,501 $1.91M 7.87% +27,501 13F-HR Timeline Group MARSHALL WACE, LLP in group MARSHALL WACE, LLP More: the full row for MARSHALL WACE, LLP 271,304 $1.9M <0.01% -302,560 13F-HR Timeline Group Diametric Capital, LP More: the full row for Diametric Capital, LP 252,193 $1.77M 0.65% new 13F-HR Timeline MILLENNIUM MANAGEMENT LLC in group MILLENNIUM MANAGEMENT LLC More: the full row for MILLENNIUM MANAGEMENT LLC 236,781 $1.66M <0.01% +174,532 13F-HR Timeline Group STATE STREET CORP in group STATE STREET CORP More: the full row for STATE STREET CORP 172,864 $1.21M <0.01% +75,529 13F-HR Timeline Group AWM Investment Company, Inc. More: the full row for AWM Investment Company, Inc. 150,000 $1.05M 0.1% new 13F-HR Timeline Woodline Partners LP More: the full row for Woodline Partners LP 150,000 $1.05M <0.01% new 13F-HR Timeline TD Asset Management Inc More: the full row for TD Asset Management Inc 145,180 $1.02M <0.01% new 13F-HR Timeline HighTower Advisors, LLC More: the full row for HighTower Advisors, LLC 132,459 $927K <0.01% -3,501 13F-HR Timeline UBS Group AG in group UBS Group AG More: the full row for UBS Group AG 126,402 $885K <0.01% +121,329 13F-HR Timeline Group BRIDGEWAY CAPITAL MANAGEMENT, LLC More: the full row for BRIDGEWAY CAPITAL MANAGEMENT, LLC 120,449 $843K 0.02% +25,000 13F-HR Timeline TWO SIGMA INVESTMENTS, LP in group TWO SIGMA INVESTMENTS, LP More: the full row for TWO SIGMA INVESTMENTS, LP 107,871 $755K <0.01% +89,318 13F-HR Timeline Group Hudson Bay Capital Management LP in group Hudson Bay Capital Management… More: the full row for Hudson Bay Capital Management LP 102,448 $717K <0.01% new 13F-HR/A Timeline Group NORTHERN TRUST CORP in group NORTHERN TRUST CORP More: the full row for NORTHERN TRUST CORP 92,040 $644K <0.01% +52,311 13F-HR Timeline Group Avidity Partners Management LP More: the full row for Avidity Partners Management LP 90,900 $636K 0.14% new 13F-HR Timeline Kingsview Wealth Management, LLC More: the full row for Kingsview Wealth Management, LLC 90,000 $630K 0.01% +76,000 13F-HR Timeline PRELUDE CAPITAL MANAGEMENT, LLC More: the full row for PRELUDE CAPITAL MANAGEMENT, LLC 72,467 $507K 0.04% new 13F-HR Timeline ROYAL BANK OF CANADA in group ROYAL BANK OF CANADA More: the full row for ROYAL BANK OF CANADA 71,000 $497K <0.01% +50,040 13F-HR Timeline Group MANUFACTURERS LIFE INSURANCE COMPANY, T… in group MANUFACTURERS LIFE INSURANCE … More: the full row for MANUFACTURERS LIFE INSURANCE COMPANY, THE 69,274 $485K <0.01% new 13F-HR Timeline Group XTX Topco Ltd in group XTX Topco Ltd More: the full row for XTX Topco Ltd 64,040 $448K 0.02% +37,211 13F-HR Timeline Group CIBC Private Wealth Group LLC in group CIBC Bancorp USA Inc. More: the full row for CIBC Private Wealth Group LLC 50,051 $350K <0.01% +35,051 13F-HR Timeline Group Palumbo Wealth Management LLC More: the full row for Palumbo Wealth Management LLC 49,052 $343K 0.11% new 13F-HR Timeline AMERIPRISE FINANCIAL INC in group AMERIPRISE FINANCIAL INC More: the full row for AMERIPRISE FINANCIAL INC 47,299 $331K <0.01% new 13F-HR Timeline Group Tidemark, LLC More: the full row for Tidemark, LLC 44,400 $311K 0.09% 0 13F-HR Timeline BANK OF AMERICA CORP /DE/ in group BANK OF AMERICA CORP /DE/ More: the full row for BANK OF AMERICA CORP /DE/ 43,754 $306K <0.01% +15,262 13F-HR/A Timeline Group GSA CAPITAL PARTNERS LLP More: the full row for GSA CAPITAL PARTNERS LLP 37,836 $265K 0.02% new 13F-HR Timeline Corient Private Wealth LP in group Corient Private Wealth LP More: the full row for Corient Private Wealth LP 36,090 $253K <0.01% -27,650 13F-HR Timeline Group RENAISSANCE TECHNOLOGIES LLC More: the full row for RENAISSANCE TECHNOLOGIES LLC 35,000 $245K <0.01% +16,800 13F-HR Timeline Flower City Capital More: the full row for Flower City Capital 29,229 $205K 0.11% -2,800 13F-HR Timeline Berman McAleer LLC More: the full row for Berman McAleer LLC 25,000 $175K 0.02% 13F-HR Timeline FIRST MANHATTAN CO. LLC. More: the full row for FIRST MANHATTAN CO. LLC. 24,245 $170K <0.01% -8,080 13F-HR Timeline Quadrature Capital Ltd in group Quadrature Capital Ltd More: the full row for Quadrature Capital Ltd 23,785 $166K <0.01% new 13F-HR Timeline Group ALETHEA CAPITAL MANAGEMENT, LLC More: the full row for ALETHEA CAPITAL MANAGEMENT, LLC 22,935 $161K 0.1% 0 13F-HR Timeline LPL Financial LLC More: the full row for LPL Financial LLC 22,400 $157K <0.01% new 13F-HR Timeline CHARLES SCHWAB INVESTMENT MANAGEMENT INC in group Charles Schwab Trust Co More: the full row for CHARLES SCHWAB INVESTMENT MANAGEMENT INC 22,344 $156K <0.01% +10,344 13F-HR Timeline Group BARCLAYS PLC in group BARCLAYS PLC More: the full row for BARCLAYS PLC 22,118 $155K <0.01% +12,194 13F-HR/A Timeline Group Vontobel Holding Ltd. in group Vontobel Holding Ltd. More: the full row for Vontobel Holding Ltd. 21,500 $150K <0.01% new 13F-HR Timeline Group PNC Financial Services Group, Inc. in group PNC Financial Services Group,… More: the full row for PNC Financial Services Group, Inc. 20,000 $140K <0.01% 0 13F-HR Timeline Group HEIGHTS CAPITAL MANAGEMENT, INC in group HEIGHTS CAPITAL MANAGEMENT, I… More: the full row for HEIGHTS CAPITAL MANAGEMENT, INC 20,000 $140K 0.04% new 13F-HR/A Timeline Group Resonant Capital Advisors, LLC More: the full row for Resonant Capital Advisors, LLC 20,000 $140K 0.01% new 13F-HR Timeline DIMENSIONAL FUND ADVISORS LP in group DIMENSIONAL FUND ADVISORS LP More: the full row for DIMENSIONAL FUND ADVISORS LP 19,562 $137K <0.01% +6,196 13F-HR Timeline Group WELLS FARGO & COMPANY/MN in group WELLS FARGO & COMPANY/MN More: the full row for WELLS FARGO & COMPANY/MN 15,000 $105K <0.01% +5,000 13F-HR Timeline Group WENDELL DAVID ASSOCIATES INC More: the full row for WENDELL DAVID ASSOCIATES INC 15,000 $105K 0.01% new 13F-HR Timeline Virtu Financial LLC in group Virtu Financial LLC More: the full row for Virtu Financial LLC 13,994 $98K 0.01% new 13F-HR Timeline Group Moors & Cabot, Inc. More: the full row for Moors & Cabot, Inc. 11,000 $77K <0.01% new 13F-HR Timeline MERCER GLOBAL ADVISORS INC /ADV More: the full row for MERCER GLOBAL ADVISORS INC /ADV 10,000 $70K <0.01% new 13F-HR Timeline Future Financial Wealth Managment LLC More: the full row for Future Financial Wealth Managment LLC 5,000 $35K 0.02% new 13F-HR Timeline The filing omitted confidential holdings, a later amendment may add them. China Universal Asset Management Co., L… More: the full row for China Universal Asset Management Co., Ltd. 5,000 $35K <0.01% new 13F-HR Timeline OSAIC HOLDINGS, INC. in group OSAIC HOLDINGS, INC. More: the full row for OSAIC HOLDINGS, INC. 4,300 $30.1K <0.01% 0 13F-HR Timeline Group JPMORGAN CHASE & CO in group JPMORGAN CHASE & CO More: the full row for JPMORGAN CHASE & CO 1,500 $10.5K <0.01% -474 13F-HR/A Timeline Group CITIGROUP INC in group CITIGROUP INC More: the full row for CITIGROUP INC 796 $5.57K <0.01% 0 13F-HR Timeline Group EverSource Wealth Advisors, LLC in group EverSource Wealth Advisors, L… More: the full row for EverSource Wealth Advisors, LLC 432 $3.02K <0.01% +87 13F-HR Timeline Group BNP PARIBAS FINANCIAL MARKETS in group BNP PARIBAS FINANCIAL MARKETS More: the full row for BNP PARIBAS FINANCIAL MARKETS 262 $1.83K <0.01% -25 13F-HR Timeline Group