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Disclosery

AGEN AGENUS INC

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COM NEW (common), issuer CIK 1098972

93 managers (96 13F filers) reported a position in AGEN shares at 2025-12-31, 10,124,300 shares in all. 20 filers opened a position and 10 filers sold out during the quarter.

Managers
93
13F filers
96
New
20
Added
24
Reduced
30
Sold out
10
Shares held by filers
10,124,300

Shares held by filers adds up every 13F filer's report, so a share reported by a parent and by its subsidiary counts twice (H9). Managers counts each filer group once.

13D and 13G filers

No 13D or 13G on this security in the data. Structured 13D/G data starts 2024-12-18.

Insider trades

No Form 4 transaction on this security in the data.

13F holders, Q4 2025

Filers in the available 13F reports with a share position at 2025-12-31, filer groups collapsed to one row (method), largest first. Options and principal amounts are left out. A group row states no % of portfolio, since each member reports its own portfolio: the members' percents are listed under it. A value about 1,000 times or 1/1,000 of the price other filers imply is shown as filed but neither ranks the row nor enters a sum.

HolderSharesValue% of portfolioChangeSource
VANGUARD GROUP INCgroup of 2 filers holding2,850,567$8.95M+260,885Timeline
Siren, L.L.C.in group Siren, L.L.C.1,064,250$3.34M0.1%013F-HRTimelineGroup
ACADIAN ASSET MANAGEMENT LLCin group ACADIAN ASSET MANAGEMENT LLC622,484$1.95M<0.01%+417,39313F-HRTimelineGroup
BlackRock, Inc.in group BlackRock, Inc.558,345$1.75M<0.01%+11,23313F-HRTimelineGroup
RENAISSANCE TECHNOLOGIES LLC543,546$1.71M<0.01%+477,34613F-HRTimeline
CITADEL ADVISORS LLCin group CITADEL ADVISORS LLC423,242$1.33M<0.01%new13F-HRTimelineGroup
GEODE CAPITAL MANAGEMENT, LLCin group GEODE CAPITAL MANAGEMENT, LLC372,748$1.17M<0.01%+25,75713F-HRTimelineGroup
SUSQUEHANNA INTERNATIONAL GROUP, LLPgroup of 2 filers holding293,087$920K-66,088Timeline
MORGAN STANLEYin group MORGAN STANLEY285,198$896K<0.01%-263,92813F-HR/ATimelineGroup
MILLENNIUM MANAGEMENT LLCin group MILLENNIUM MANAGEMENT LLC225,339$708K<0.01%-123,41513F-HRTimelineGroup
Jump Financial, LLCin group Jump Financial, LLC170,407$535K0.01%+28,91313F-HRTimelineGroup
PANAGORA ASSET MANAGEMENT INC163,148$512K<0.01%+36,96413F-HRTimeline
TWO SIGMA INVESTMENTS, LPgroup of 2 filers holding151,362$475K+49,009Timeline
MARSHALL WACE, LLPin group MARSHALL WACE, LLP146,800$461K<0.01%+33,48713F-HRTimelineGroup
RAYMOND JAMES FINANCIAL INCin group RAYMOND JAMES FINANCIAL INC141,653$445K<0.01%-4,10713F-HRTimelineGroup
STATE STREET CORPin group STATE STREET CORP137,383$431K<0.01%-13,20013F-HRTimelineGroup
D. E. Shaw & Co., Inc.in group D. E. Shaw & Co., Inc.127,638$401K<0.01%+13,30913F-HRTimelineGroup
Walleye Capital LLCin group Walleye Capital LLC123,458$388K<0.01%-187,33013F-HRTimelineGroup
UBS Group AGin group UBS Group AG118,818$373K<0.01%+36,88113F-HRTimelineGroup
683 Capital Management, LLCin group 683 Capital Management, LLC114,336$359K0.03%new13F-HRTimelineGroup
Man Group plcin group Man Group plc114,204$359K<0.01%new13F-HRTimelineGroup
Point72 Asset Management, L.P.in group Point72 Asset Management, L.P.108,220$340K<0.01%new13F-HRTimelineGroup
OMERS ADMINISTRATION Corp100,500$316K<0.01%new13F-HRTimeline
NORTHERN TRUST CORPin group NORTHERN TRUST CORP89,586$281K<0.01%+7,88813F-HRTimelineGroup
JANE STREET GROUP, LLCin group JANE STREET GROUP, LLC73,572$231K<0.01%+20,79413F-HRTimelineGroup
Connor, Clark & Lunn Investment Managem…67,959$213K<0.01%new13F-HRTimeline
CANADA PENSION PLAN INVESTMENT BOARD66,100$208K<0.01%new13F-HRTimeline
GOLDMAN SACHS GROUP INCin group GOLDMAN SACHS GROUP INC61,749$194K<0.01%+16,03413F-HR/ATimelineGroup
Squarepoint Ops LLCin group Squarepoint Ops LLC55,142$173K<0.01%+41,17913F-HRTimelineGroup
ExodusPoint Capital Management, LP47,461$149K<0.01%new13F-HRTimeline
BARCLAYS PLCin group BARCLAYS PLC46,273$145K<0.01%+36,05313F-HRTimelineGroup
Avestar Capital, LLC41,000$129K0.01%013F-HRTimeline
Qube Research & Technologies Ltd39,895$125K<0.01%new13F-HRTimeline
Engineers Gate Manager LP35,279$111K<0.01%+2513F-HRTimeline
Virtu Financial LLCin group Virtu Financial LLC34,385$108K<0.01%new13F-HRTimelineGroup
Graham Capital Management, L.P.31,706$99.6K<0.01%-23,11413F-HRTimeline
Ovata Capital Management Ltdin group Ovata Capital Management Ltd30,800$96.7K0.01%new13F-HR/ATimelineGroup
CAPTRUST FINANCIAL ADVISORS30,087$94.5K<0.01%-59713F-HRTimeline
Key Client Fiduciary Advisors, LLC27,348$85.9K0.03%-11,88513F-HRTimeline
OSAIC HOLDINGS, INC.in group OSAIC HOLDINGS, INC.27,139$85.2K<0.01%-6,82613F-HRTimelineGroup
HighTower Advisors, LLC25,142$78.9K<0.01%-15013F-HRTimeline
PRICE T ROWE ASSOCIATES INC /MD/24,500$77K<0.01%new13F-HRTimeline
LPL Financial LLC23,326$73.2K<0.01%+3,94313F-HRTimeline
GROUP ONE TRADING LLC22,239$69.8K<0.01%new13F-HRTimeline
Lighthouse Investment Partners, LLCin group Lighthouse Investment Partner…18,720$58.8K<0.01%new13F-HRTimelineGroup
HSBC HOLDINGS PLCin group HSBC HOLDINGS PLC17,056$54.2K<0.01%013F-HR/ATimelineGroup
Quadrature Capital Ltdin group Quadrature Capital Ltd17,121$53.8K<0.01%new13F-HRTimelineGroup
BANK OF MONTREAL /CAN/in group BANK OF MONTREAL /CAN/16,207$50.9K<0.01%+213F-HRTimelineGroup
SHERBROOKE PARK ADVISERS LLC15,390$48.3K0.12%-1,16713F-HRTimeline
CHARLES SCHWAB INVESTMENT MANAGEMENT INCin group Charles Schwab Trust Co15,061$47.3K<0.01%-513F-HRTimelineGroup
PRELUDE CAPITAL MANAGEMENT, LLC14,500$45.5K<0.01%new13F-HRTimeline
Redwood Family Wealth LLC14,140$44.4K0.04%13F-HRTimeline
BANK OF AMERICA CORP /DE/in group BANK OF AMERICA CORP /DE/13,246$41.6K<0.01%-356,06813F-HRTimelineGroup
R Squared Ltd13,129$41.2K0.02%new13F-HRTimeline
Post Resch Tallon Group Inc.12,750$40K0.03%-7,25013F-HRTimeline
AQR CAPITAL MANAGEMENT LLCin group AQR CAPITAL MANAGEMENT LLC11,576$36.3K<0.01%-15,70313F-HRTimelineGroup
Values First Advisors, Inc.11,065$34.7K0.02%-2,27013F-HRTimeline
NewEdge Advisors, LLC10,596$33.3K<0.01%-33,85013F-HRTimeline
WELLS FARGO & COMPANY/MNin group WELLS FARGO & COMPANY/MN10,184$32K<0.01%-3,13713F-HRTimelineGroup
MSA Advisors, LLC10,000$31.4K0.01%013F-HRTimeline
EP Wealth Advisors, LLC10,000$31.4K<0.01%13F-HRTimeline
Tower Research Capital LLC (TRC)in group Tower Research Capital LLC (T…8,402$26.4K<0.01%+2,85713F-HRTimelineGroup
FMR LLCin group FMR LLC5,429$17K<0.01%-26413F-HRTimelineGroup
First Command Advisory Services, Inc.3,530$11.1K<0.01%013F-HRTimeline
Pinnacle Wealth Planning Services, Inc.3,373$10.6K<0.01%new13F-HRTimeline
ROYAL BANK OF CANADAin group ROYAL BANK OF CANADA2,129$7K<0.01%-10,70813F-HRTimelineGroup
CoreCap Advisors, LLC2,000$6.28K<0.01%013F-HRTimeline
CWM, LLCin group CWM, LLC1,917$6K<0.01%-3,04413F-HRTimelineGroup
Optiver Holding B.V.in group Optiver Holding B.V.1,373$4.31K<0.01%+1,35313F-HRTimelineGroup
CHILTON CAPITAL MANAGEMENT LLC1,058$3.32K<0.01%013F-HRTimeline
Covestor Ltd1,011$3K<0.01%013F-HRTimeline
NORTHWESTERN MUTUAL WEALTH MANAGEMENT COin group NORTHWESTERN MUTUAL INVESTMEN…633$1.99K<0.01%-7513F-HR/ATimelineGroup
Physician Wealth Advisors, Inc.621$1.95K<0.01%013F-HRTimeline
Game Plan Financial Advisors, LLC585$1.84K<0.01%013F-HRTimeline
RHUMBLINE ADVISERS538$1.69K<0.01%013F-HRTimeline
HUNTINGTON NATIONAL BANKin group HUNTINGTON NATIONAL BANK500$1.57K<0.01%013F-HRTimelineGroup
Russell Investments Group, Ltd.in group Russell Investments Group, Lt…433$1.36K<0.01%-2,78413F-HRTimelineGroup
NISA INVESTMENT ADVISORS, LLC410$1.29K<0.01%013F-HRTimeline
JPMORGAN CHASE & COin group JPMORGAN CHASE & CO382$1.2K<0.01%-28,69813F-HRTimelineGroup
JONES FINANCIAL COMPANIES LLLPin group JONES FINANCIAL COMPANIES LLLP371$1.17K<0.01%013F-HRTimelineGroup
Rialto Wealth Management, LLC305$958<0.01%013F-HRTimeline
Fortitude Family Office, LLC296$929<0.01%013F-HRTimeline
EverSource Wealth Advisors, LLCin group EverSource Wealth Advisors, L…274$860<0.01%013F-HRTimelineGroup
Atlantic Union Bankshares Corpin group Atlantic Union Bankshares Corp250$785<0.01%013F-HRTimelineGroup
Federation des caisses Desjardins du Qu…100$314<0.01%013F-HRTimeline
BNP PARIBAS FINANCIAL MARKETSin group BNP PARIBAS FINANCIAL MARKETS96$301<0.01%+1913F-HRTimelineGroup
Allworth Financial LP58$183<0.01%+5013F-HRTimeline
Root Financial Partners, LLC25$79<0.01%013F-HRTimeline
IFP Advisors, Inc15$47<0.01%-113F-HRTimeline
HORIZON FINANCIAL SERVICES, LLC9$28<0.01%new13F-HRTimeline
Arax Advisory Partners5$16<0.01%-66213F-HRTimeline
Parallel Advisors, LLC5$16<0.01%-1913F-HRTimeline
SBI Securities Co., Ltd.5$16<0.01%-30113F-HRTimeline