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CHI Advisors LLC

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13F filer, CIK 1791468, NEW YORK, NY

CHI Advisors LLC reported $376,700,182 across 24 holdings for the quarter ended 2023-03-31, in a 13F-HR filed 2023-05-11. Its ten largest share positions make up 89.71% of the portfolio.

Filed (acceptance time not in the bulk data set), ingested 13F-HR 0001085146-23-002240

Period
2023-03-31
Reported value
$377M
Holdings
24
Top 10 weight
89.71%
New
5
Sold out
4

Largest buys vs the previous quarter

SecurityShares changeApprox. value
2SEVENTY BIO INC COMMON STO…added+521,748$5.32M
ORCHARD THERAPEUTICS PLCnew+785,738$4.22M
CHINOOK THERAPEUTICS INCnew+135,000$3.13M
SYRSnew+767,445$2.05M
KROSadded+46,000$1.96M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Largest sells vs the previous quarter

SecurityShares changeApprox. value
INOZYME PHARMA INCreduced-862,685-$4.94M
PLRXreduced-168,057-$4.47M
KEZAR LIFE SCIENCES INCreduced-1,200,000-$3.76M
LRMRreduced-727,101-$3.29M
ORCHARD THERAPEUTICS PLCexited-7,987,396-$2.96M

Ranked by the share change valued at this quarter's implied price (value over shares in the 13F). A position sold out is valued at the previous quarter's price, its last report.

Holdings, Q1 2023

Share positions as resolved from 13F-HR 0001085146-23-002240, largest first. % of portfolio is the value over $376,592,057, the sum of the share positions whose value is usable for ratios (method).

SecurityHistorySharesValue% of portfolioChangeLatest eventTimeline
PROMETHEUS BIOSCIENCES INCPROMETHEUS BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: 1,752,243 shares; 2022Q1: 1,585,096 shares; 2022Q2: 1,671,976 shares; 2022Q3: 1,601,785 shares; 2022Q4: 923,800 shares; 2023Q1: 934,135 shares 934,135$100M26.62%+10,335
PLRXPLIANT THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: 2,569,479 shares; 2022Q1: 2,657,457 shares; 2022Q2: 3,106,807 shares; 2022Q3: 3,409,758 shares; 2022Q4: 3,169,892 shares; 2023Q1: 3,001,835 shares 3,001,835$79.8M21.2%-168,057Timeline
VECTIVBIO HLDG AGVECTIVBIO HLDG AGQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: 2,675,408 shares; 2022Q1: 3,084,310 shares; 2022Q2: 3,782,199 shares; 2022Q3: 4,119,572 shares; 2022Q4: 5,492,893 shares; 2023Q1: 5,255,484 shares 5,255,484$44.7M11.88%-237,409
CGEMCULLINAN THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: 2,476,720 shares; 2022Q1: 2,753,047 shares; 2022Q2: 3,047,609 shares; 2022Q3: 3,243,185 shares; 2022Q4: 3,317,544 shares; 2023Q1: 3,349,460 shares 3,349,460$34.3M9.1%+31,916Timeline
REPARE THERAPEUTICS INCREPARE THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: 2,212,256 shares; 2022Q1: 2,581,097 shares; 2022Q2: 2,646,781 shares; 2022Q3: 3,069,847 shares; 2022Q4: 2,800,126 shares; 2023Q1: 2,997,939 shares 2,997,939$29.5M7.83%+197,813
LRMRLARIMAR THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: 1,515,148 shares; 2022Q1: 1,515,148 shares; 2022Q2: 1,515,148 shares; 2022Q3: 3,415,148 shares; 2022Q4: 3,473,366 shares; 2023Q1: 2,746,265 shares 2,746,265$12.4M3.3%-727,101Timeline
KROSKEROS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: 17,518 shares; 2022Q1: 62,229 shares; 2022Q2: 103,429 shares; 2022Q3: 200,229 shares; 2022Q4: 215,059 shares; 2023Q1: 261,059 shares 261,059$11.1M2.96%+46,000Timeline
CMPXCOMPASS THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: 3,023,692 shares; 2022Q1: 2,829,712 shares; 2022Q2: 2,829,712 shares; 2022Q3: 2,829,712 shares; 2022Q4: 2,829,712 shares; 2023Q1: 2,829,712 shares 2,829,712$9.25M2.46%0Timeline
2SEVENTY BIO INC COMMON STO…2SEVENTY BIO INC COMMON STOCKQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: not reported; 2022Q1: 819,672 shares; 2022Q2: 819,672 shares; 2022Q3: 530,223 shares; 2022Q4: 333,252 shares; 2023Q1: 855,000 shares 855,000$8.72M2.32%+521,748
INOZYME PHARMA INCINOZYME PHARMA INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: 892,057 shares; 2022Q1: 892,057 shares; 2022Q2: 2,033,802 shares; 2022Q3: 1,996,277 shares; 2022Q4: 2,204,876 shares; 2023Q1: 1,342,191 shares 1,342,191$7.69M2.04%-862,685
OMEGA THERAPEUTICS INCOMEGA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: 1,055,882 shares; 2022Q1: 1,055,882 shares; 2022Q2: 1,055,882 shares; 2022Q3: 1,055,882 shares; 2022Q4: 1,055,882 shares; 2023Q1: 1,055,882 shares 1,055,882$6.37M1.69%0
IKENA ONCOLOGY INCIKENA ONCOLOGY INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: 814,756 shares; 2022Q1: 814,755 shares; 2022Q2: 1,090,937 shares; 2022Q3: 1,214,304 shares; 2022Q4: 1,637,372 shares; 2023Q1: 1,660,872 shares 1,660,872$5.73M1.52%+23,500
RALLYBIO CORPRALLYBIO CORPQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: not reported; 2022Q1: not reported; 2022Q2: not reported; 2022Q3: 194,297 shares; 2022Q4: 726,109 shares; 2023Q1: 760,543 shares 760,543$4.34M1.15%+34,434
ORCHARD THERAPEUTICS PLCORCHARD THERAPEUTICS PLCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: not reported; 2022Q1: not reported; 2022Q2: not reported; 2022Q3: not reported; 2022Q4: not reported; 2023Q1: 785,738 shares 785,738$4.22M1.12%new
CHINOOK THERAPEUTICS INCCHINOOK THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: not reported; 2022Q1: not reported; 2022Q2: not reported; 2022Q3: not reported; 2022Q4: not reported; 2023Q1: 135,000 shares 135,000$3.13M0.83%new
PRECISION BIOSCIENCES INCPRECISION BIOSCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: 606,629 shares; 2022Q1: 606,629 shares; 2022Q2: 3,003,751 shares; 2022Q3: 3,674,820 shares; 2022Q4: 3,549,820 shares; 2023Q1: 3,469,820 shares 3,469,820$2.61M0.69%-80,000
OVIDOVID THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: 400,000 shares; 2022Q1: 852,888 shares; 2022Q2: 864,822 shares; 2022Q3: 864,822 shares; 2022Q4: 864,822 shares; 2023Q1: 864,822 shares 864,822$2.23M0.59%0Timeline
KEZAR LIFE SCIENCES INCKEZAR LIFE SCIENCES INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: 272,250 shares; 2022Q1: 314,612 shares; 2022Q2: 1,840,793 shares; 2022Q3: 1,762,793 shares; 2022Q4: 1,889,451 shares; 2023Q1: 689,451 shares 689,451$2.16M0.57%-1,200,000
FREELINE THERAPEUTICS HLDGSFREELINE THERAPEUTICS HLDGSQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: 1,876,389 shares; 2022Q1: 4,862,319 shares; 2022Q2: 4,862,319 shares; 2022Q3: 4,814,419 shares; 2022Q4: 4,814,419 shares; 2023Q1: 4,729,419 shares 4,729,419$2.15M0.57%-85,000
CRVSCORVUS PHARMACEUTICALS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: 400,000 shares; 2022Q1: 1,703,137 shares; 2022Q2: 2,214,184 shares; 2022Q3: 2,384,402 shares; 2022Q4: 2,384,402 shares; 2023Q1: 2,339,402 shares 2,339,402$2.13M0.57%-45,000Timeline
SYRSSYROS PHARMACEUTICALS INC COMQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: not reported; 2022Q1: not reported; 2022Q2: not reported; 2022Q3: not reported; 2022Q4: not reported; 2023Q1: 767,445 shares 767,445$2.05M0.54%newTimeline
TRDAENTRADA THERAPEUTICS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: not reported; 2022Q1: not reported; 2022Q2: 163,496 shares; 2022Q3: not reported; 2022Q4: not reported; 2023Q1: 56,374 shares 56,374$817K0.22%newTimeline
ONCORUS INCONCORUS INCQuarterly shares; oldest to newest; scale is this security's eight-quarter maximum; 2021Q2: restricted; 2021Q3: restricted; 2021Q4: 2,106,903 shares; 2022Q1: 2,417,436 shares; 2022Q2: 2,367,436 shares; 2022Q3: 2,367,436 shares; 2022Q4: 2,367,436 shares; 2023Q1: 2,367,436 shares 2,367,436$815K0.22%0

Options

Puts and calls, as filed. The amount and value describe the underlying shares, not the option premium, so they stay out of % of portfolio (H5).

SecurityTypeAmountValueChange
PROMETHEUS BIOSCIENCES INCPROMETHEUS BIOSCIENCES INC COMcall25,000$108Knew

Sold out in Q1 2023

Positions in the previous quarter's report that this quarter's report no longer lists.

SecurityShares beforeValue beforeType
ORCHARD THERAPEUTICS PLCORCHARD THERAPEUTICS PLC7,987,396$2.96Mshares
G1 THERAPEUTICS INCG1 THERAPEUTICS INC333,945$1.81Mshares
DIREXION SHS ETF TRDIREXION SHS ETF TR25,000$431Kshares
PLRXPLIANT THERAPEUTICS INC30,000$29.2Kcall

How Q1 2023 was built

Available 13F filings of this filer for the quarter and their roles: the base report is the latest original or restatement, NEW HOLDINGS amendments filed after it are added (method).

FilingRoleAmendmentFiledAcceptedIngested
13F-HR 0001085146-23-002240 base2023-05-11acceptance time not in the bulk data set